(Q38157408)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24176765%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

title

The role of CYP11A1 in the production of vitamin D metabolites and their role in the regulation of epidermal functions (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24176765%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

0 references

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24176765%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Robert C Tuckey

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24176765%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

3

Wei Li

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24176765%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

author name string

Tae-Kang Kim

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24176765%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Ae-Kyung Yi

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24176765%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Arnold Postlethwaite

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24176765%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

language of work or name

1 reference

28 October 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24176765%20AND%20SRC:MED&resulttype=core&format=json

The Journal of Steroid Biochemistry and Molecular Biology

29 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24176765%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

volume

144 Pt A

1 reference

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29 February 2020

page(s)

28-39

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24176765%20AND%20SRC:MED&resulttype=core&format=json

Effects of sidechain length and composition on the kinetic conversion and product distribution of vitamin D analogs determined by real-time NMR.

29 February 2020

cites work

1 reference

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6 September 2017

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Vitamin D receptor inhibits nuclear factor κB activation by interacting with IκB kinase β protein

6 September 2017

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6 September 2017

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Hydroxylation of CYP11A1-derived products of vitamin D3 metabolism by human and mouse CYP27B1.

6 September 2017

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Steroidogenesis in the skin: implications for local immune functions

6 September 2017

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20S-hydroxyvitamin D3, noncalcemic product of CYP11A1 action on vitamin D3, exhibits potent antifibrogenic activity in vivo

6 September 2017

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Expression of the vitamin D-activating enzyme 1α-hydroxylase (CYP27B1) decreases during melanoma progression

6 September 2017

1 reference

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Novel vitamin D hydroxyderivatives inhibit melanoma growth and show differential effects on normal melanocytes

6 September 2017

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Sensing the environment: regulation of local and global homeostasis by the skin's neuroendocrine system

6 September 2017

1 reference

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Cytochrome P450scc-dependent metabolism of 7-dehydrocholesterol in placenta and epidermal keratinocytes

6 September 2017

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Epigenetic regulation of gene expression in keratinocytes

6 September 2017

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Epithelial antimicrobial defence of the skin and intestine

6 September 2017

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In vivo evidence for a novel pathway of vitamin D₃ metabolism initiated by P450scc and modified by CYP27B1.

6 September 2017

1 reference

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New vitamin D analogs as potential therapeutics in melanoma

6 September 2017

1 reference

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The multitasking organ: recent insights into skin immune function

6 September 2017

1 reference

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Human cytochrome P450scc (CYP11A1) catalyzes epoxide formation with ergosterol.

6 September 2017

1 reference

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L-tyrosine and L-dihydroxyphenylalanine as hormone-like regulators of melanocyte functions

6 September 2017

1 reference

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Production of 22-hydroxy metabolites of vitamin d3 by cytochrome p450scc (CYP11A1) and analysis of their biological activities on skin cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002668

Cutaneous hypothalamic-pituitary-adrenal axis homolog: regulation by ultraviolet radiation

6 September 2017

1 reference

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Vitamin D metabolism and function in the skin

6 September 2017

1 reference

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Structural basis for pregnenolone biosynthesis by the mitochondrial monooxygenase system

6 September 2017

1 reference

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Extra-adrenal glucocorticoids and mineralocorticoids: evidence for local synthesis, regulation, and function.

6 September 2017

1 reference

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Expression of vitamin D receptor decreases during progression of pigmented skin lesions.

6 September 2017

1 reference

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Vitamin D analogs 17,20S(OH)2pD and 17,20R(OH)2pD are noncalcemic and exhibit antifibrotic activity.

6 September 2017

1 reference

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Vitamin D: an ancient hormone

6 September 2017

1 reference

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20-Hydroxyvitamin D2 is a noncalcemic analog of vitamin D with potent antiproliferative and prodifferentiation activities in normal and malignant cells

6 September 2017

1 reference

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The molecular biology, biochemistry, and physiology of human steroidogenesis and its disorders

6 September 2017

1 reference

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Purified mouse CYP27B1 can hydroxylate 20,23-dihydroxyvitamin D3, producing 1alpha,20,23-trihydroxyvitamin D3, which has altered biological activity

6 September 2017

1 reference

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Products of vitamin D3 or 7-dehydrocholesterol metabolism by cytochrome P450scc show anti-leukemia effects, having low or absent calcemic activity.

6 September 2017

1 reference

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20-Hydroxycholecalciferol, product of vitamin D3 hydroxylation by P450scc, decreases NF-kappaB activity by increasing IkappaB alpha levels in human keratinocytes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002668

The osteogenic transcription factor runx2 controls genes involved in sterol/steroid metabolism, including CYP11A1 in osteoblasts

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002668

Sequential metabolism of 7-dehydrocholesterol to steroidal 5,7-dienes in adrenal glands and its biological implication in the skin

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002668

Synthesis and photo-conversion of androsta- and pregna-5,7-dienes to vitamin D3-like derivatives

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002668

Photo-conversion of two epimers (20R and 20S) of pregna-5,7-diene-3beta, 17alpha, 20-triol and their bioactivity in melanoma cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002668

Metabolism of 1alpha-hydroxyvitamin D3 by cytochrome P450scc to biologically active 1alpha,20-dihydroxyvitamin D3.

6 September 2017

1 reference

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Pathways and products for the metabolism of vitamin D3 by cytochrome P450scc

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002668

20-Hydroxyvitamin D3, a product of vitamin D3 hydroxylation by cytochrome P450scc, stimulates keratinocyte differentiation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002668

Sunlight, UV-radiation, vitamin D and skin cancer: how much sunlight do we need?

6 September 2017

1 reference

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The CCHCR1 (HCR) gene is relevant for skin steroidogenesis and downregulated in cultured psoriatic keratinocytes

6 September 2017

1 reference

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Differential expression of HPA axis homolog in the skin

6 September 2017

1 reference

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Extra precision glide: docking and scoring incorporating a model of hydrophobic enclosure for protein-ligand complexes

6 September 2017

1 reference

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Characterization of a ultraviolet B-induced corticotropin-releasing hormone-proopiomelanocortin system in human melanocytes

6 September 2017

1 reference

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Progesterone synthesis by the human placenta

6 September 2017

1 reference

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A novel pathway for sequential transformation of 7-dehydrocholesterol and expression of the P450scc system in mammalian skin

6 September 2017

1 reference

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Melanin pigmentation in mammalian skin and its hormonal regulation

6 September 2017

1 reference

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The implications of 7-dehydrosterol-7-reductase deficiency (Smith-Lemli-Opitz syndrome) to neurosteroid production

6 September 2017

1 reference

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A pathway for the metabolism of vitamin D3: unique hydroxylated metabolites formed during catalysis with cytochrome P450scc (CYP11A1).

6 September 2017

1 reference

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Human skin is a steroidogenic tissue: steroidogenic enzymes and cofactors are expressed in epidermis, normal sebocytes, and an immortalized sebocyte cell line (SEB-1)

6 September 2017

1 reference

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Cutaneous expression of corticotropin-releasing hormone (CRH), urocortin, and CRH receptors

6 September 2017

1 reference

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Neuroendocrinology of the skin

6 September 2017

1 reference

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Corticotropin releasing hormone and proopiomelanocortin involvement in the cutaneous response to stress

6 September 2017

1 reference

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The crystal structure of the nuclear receptor for vitamin D bound to its natural ligand

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002668

20-hydroxyvitamin D₃ inhibits proliferation of cancer cells with high efficacy while being non-toxic.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002668

High basal NF-κB activity in nonpigmented melanoma cells is associated with an enhanced sensitivity to vitamin D3 derivatives.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002668

Synthesis and photochemical transformation of 3β,21-dihydroxypregna-5,7-dien-20-one to novel secosteroids that show anti-melanoma activity.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002668

Chemical synthesis of 20S-hydroxyvitamin D3, which shows antiproliferative activity.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002668

Molecular biology of steroid hormone synthesis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002668

A new steroidal 5,7-diene derivative, 3beta-hydroxyandrosta-5,7-diene-17beta-carboxylic acid, shows potent anti-proliferative activity

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002668

Enzymatic metabolism of ergosterol by cytochrome p450scc to biologically active 17alpha,24-dihydroxyergosterol

14 September 2017

1 reference

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Gene expression profiling of Caco-2 BBe cells suggests a role for specific signaling pathways during intestinal differentiation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002668

Lipopolysaccharide and CpG DNA synergize for tumor necrosis factor-alpha production through activation of NF-kappaB.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002668

The epidermal keratinocyte as a model for the study of gene regulation and cell differentiation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002668

Rat CYP24A1 acts on 20-hydroxyvitamin D(3) producing hydroxylated products with increased biological activity

28 September 2017

1 reference

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Structure and function of the stratum corneum extracellular matrix

23 June 2018

1 reference

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Correlation between secosteroid-induced vitamin D receptor activity in melanoma cells and computer-modeled receptor binding strength

23 June 2018

1 reference

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Design, synthesis, and biological action of 20R-hydroxyvitamin D3.

23 June 2018

1 reference

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Metabolism of cholesterol, vitamin D3 and 20-hydroxyvitamin D3 incorporated into phospholipid vesicles by human CYP27A1

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002668

The potential role of vitamin D in the progression of benign and malignant melanocytic neoplasms

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002668

20,23-dihydroxyvitamin D3, novel P450scc product, stimulates differentiation and inhibits proliferation and NF-kappaB activity in human keratinocytes

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002668

Metabolism of vitamin d2 to 17,20,24-trihydroxyvitamin d2 by cytochrome p450scc (CYP11A1).

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002668

Role of bacterial DNA in macrophage activation by group B streptococci

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002668

T cell responses to a non-glycosylated epitope predominate in type II collagen-immunised HLA-DRB1*0101 transgenic mice

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002668

An alternative pathway of vitamin D metabolism. Cytochrome P450scc (CYP11A1)-mediated conversion to 20-hydroxyvitamin D2 and 17,20-dihydroxyvitamin D2.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002668

The cytochrome P450scc system opens an alternate pathway of vitamin D3 metabolism.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002668

The targets of vitamin D depend on the differentiation and activation status of CD4 positive T cells

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002668

Potential mechanism of skin response to stress.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002668

Lamellar bodies: the key to cutaneous barrier function

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002668

1,25-Dihydroxyvitamin D3 acts directly on the T lymphocyte vitamin D receptor to inhibit experimental autoimmune encephalomyelitis.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002668

Colon cancer cells produce immunoregulatory glucocorticoids.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002668

Human hair follicles display a functional equivalent of the hypothalamic-pituitary-adrenal axis and synthesize cortisol

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002668

CRH stimulation of corticosteroids production in melanocytes is mediated by ACTH.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002668

Identification of 7(8) and 8(9) unsaturated adrenal steroid metabolites produced by patients with 7-dehydrosterol-delta7-reductase deficiency (Smith-Lemli-Opitz syndrome).

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002668

The importance of lipids in cutaneous function

31 August 2018

1 reference

12 December 2020

Relationship of 25-hydroxyvitamin D3 side chain structure to biological activity

1 reference

12 December 2020

Sex steroid synthesis in human skin in situ: the roles of aromatase and steroidogenic acute regulatory protein in the homeostasis of human skin

1 reference

12 December 2020

ACTH receptor, CYP11A1, CYP17 and CYP21A2 genes are expressed in skin

1 reference

12 December 2020

Ultraviolet B stimulates production of corticotropin releasing factor (CRF) by human melanocytes

1 reference

12 December 2020

Side-chain specificities of human and bovine cytochromes P-450scc

1 reference

12 December 2020

10.1016/J.JSBMB.2013.10.012

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24176765%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24176765%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24176765%20AND%20SRC:MED&resulttype=core&format=json