(Q38167861)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24295327%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

title

Targeting the type III secretion system to treat bacterial infections (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24295327%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

1

1 reference

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2 March 2020

author name string

B Brett Finlay

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24295327%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

language of work or name

English

0 references

publication date

3 December 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24295327%20AND%20SRC:MED&resulttype=core&format=json

Expert Opinion on Therapeutic Targets

2 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24295327%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

volume

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24295327%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24295327%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

page(s)

137-152

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24295327%20AND%20SRC:MED&resulttype=core&format=json

Targeting virulence: a new paradigm for antimicrobial therapy

2 March 2020

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Virulence blockers as alternatives to antibiotics: type III secretion inhibitors against Gram-negative bacteria

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Decreased diversity of the fecal Microbiome in recurrent Clostridium difficile-associated diarrhea

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The Shigella flexneri effector OspG interferes with innate immune responses by targeting ubiquitin-conjugating enzymes

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Antibiotic treatment of Escherichia coli O157 infection and the risk of hemolytic uremic syndrome, Minnesota

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N-Hydroxybenzimidazole inhibitors of ExsA MAR transcription factor in Pseudomonas aeruginosa: In vitro anti-virulence activity and metabolic stability

21 January 2018

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The type III secretion injectisome, a complex nanomachine for intracellular 'toxin' delivery

21 January 2018

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Supermolecular structure of the enteropathogenic Escherichia coli type III secretion system and its direct interaction with the EspA-sheath-like structure

21 January 2018

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Molecular characterization and assembly of the needle complex of the Salmonella typhimurium type III protein secretion system

21 January 2018

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Modulation of virulence factor expression by pathogen target cell contact

21 January 2018

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YscU recognizes translocators as export substrates of the Yersinia injectisome

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2014.855199

Regulation of type III secretion hierarchy of translocators and effectors in attaching and effacing bacterial pathogens

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2014.855199

Identification of the bile salt binding site on IpaD from Shigella flexneri and the influence of ligand binding on IpaD structure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.855199

Chaperone release and unfolding of substrates in type III secretion

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2014.855199

Real-time imaging of type III secretion: Salmonella SipA injection into host cells

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2014.855199

YopH of Yersinia pseudotuberculosis interrupts early phosphotyrosine signalling associated with phagocytosis

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2014.855199

Control of effector export by the Pseudomonas aeruginosa type III secretion proteins PcrG and PcrV.

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2014.855199

The type III secretion system needle tip complex mediates host cell sensing and translocon insertion.

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2014.855199

Expression hierarchy in the Yersinia type III secretion system established through YopD recognition of RNA

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2014.855199

Yersinia enterocolitica type III secretion: yscM1 and yscM2 regulate yop gene expression by a posttranscriptional mechanism that targets the 5' untranslated region of yop mRNA.

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2014.855199

Targeting bacterial virulence: inhibitors of type III secretion in Yersinia

21 January 2018

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Targeting type III secretion in Yersinia pestis

21 January 2018

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An inhibitor of gram-negative bacterial virulence protein secretion

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2014.855199

Visible fluorescence detection of type III protein secretion from bacterial pathogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.855199

Imaging type-III secretion reveals dynamics and spatial segregation of Salmonella effectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.855199

Quantification of real-time Salmonella effector type III secretion kinetics reveals differential secretion rates for SopE2 and SptP.

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2014.855199

Secretion of type III effectors into host cells in real time

21 January 2018

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Small molecules aimed at type III secretion systems to inhibit bacterial virulence

21 January 2018

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Cytosporone B, an inhibitor of the type III secretion system of Salmonella enterica serovar Typhimurium

21 January 2018

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A small-molecule inhibitor of the bacterial type III secretion system protects against in vivo infection with Citrobacter rodentium.

21 January 2018

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Harvesting the biological potential of the human gut microbiome

21 January 2018

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Small Molecule Inhibitors of LcrF, a Yersinia pseudotuberculosis Transcription Factor, Attenuate Virulence and Limit Infection in a Murine Pneumonia Model

21 January 2018

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N-hydroxybenzimidazole inhibitors of the transcription factor LcrF in Yersinia: novel antivirulence agents

21 January 2018

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Design, synthesis, and multivariate quantitative structure-activity relationship of salicylanilides--potent inhibitors of type III secretion in Yersinia

21 January 2018

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ATPases as drug targets: learning from their structure

21 January 2018

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Inhibitors of Helicobacter pylori ATPase Cagalpha block CagA transport and cag virulence

21 January 2018

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A new pathway for the secretion of virulence factors by bacteria: the flagellar export apparatus functions as a protein-secretion system.

21 January 2018

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Metabolic syndrome and altered gut microbiota in mice lacking Toll-like receptor 5

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.855199

Substituted 2-imino-5-arylidenethiazolidin-4-one inhibitors of bacterial type III secretion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.855199

Small-molecule type III secretion system inhibitors block assembly of the Shigella type III secreton

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.855199

Designed coiled-coil peptides inhibit the type three secretion system of enteropathogenic Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.855199

Effect of coiled-coil peptides on the function of the type III secretion system-dependent activity of enterohemorragic Escherichia coli O157:H7 and Citrobacter rodentium

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.855199

Protective anti-V antibodies inhibit Pseudomonas and Yersinia translocon assembly within host membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.855199

Protection against experimental bubonic and pneumonic plague by a recombinant capsular F1-V antigen fusion protein vaccine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.855199

Active and passive immunization with the Pseudomonas V antigen protects against type III intoxication and lung injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.855199

A synthetic bivalent ligand of CXCR4 inhibits HIV infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.855199

Enteropathogenic E. coli (EPEC) transfers its receptor for intimate adherence into mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.855199

The role of the eae gene of enterohemorrhagic Escherichia coli in intimate attachment in vitro and in a porcine model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.855199

Identification and characterization of small-molecule inhibitors of Yop translocation in Yersinia pseudotuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.855199

Inhibition of type III secretion in Salmonella enterica serovar Typhimurium by small-molecule inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.855199

Salicylidene acylhydrazides that affect type III protein secretion in Salmonella enterica serovar typhimurium

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.855199

Small molecule inhibitors of the Yersinia type III secretion system impair the development of Chlamydia after entry into host cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.855199

Reversal of the antichlamydial activity of putative type III secretion inhibitors by iron

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.855199

Characterization of the effects of salicylidene acylhydrazide compounds on type III secretion in Escherichia coli O157:H7.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.855199

Small-molecule inhibitors specifically targeting type III secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.855199

Salicylidene acylhydrazide-mediated inhibition of type III secretion system-1 in Salmonella enterica serovar Typhimurium is associated with iron restriction and can be reversed by free iron

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.855199

Structural Characterisation of Tpx from Yersinia pseudotuberculosis Reveals Insights into the Binding of Salicylidene Acylhydrazide Compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.855199

Identification of bacterial target proteins for the salicylidene acylhydrazide class of virulence-blocking compounds.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.855199

Isolation of Salmonella mutants resistant to the inhibitory effect of Salicylidene acylhydrazides on flagella-mediated motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.855199

Treatment of Chlamydia trachomatis with a small molecule inhibitor of the Yersinia type III secretion system disrupts progression of the chlamydial developmental cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.855199

Protection of mice from a Chlamydia trachomatis vaginal infection using a Salicylidene acylhydrazide, a potential microbicide

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.855199

Mutations in hemG mediate resistance to salicylidene acylhydrazides, demonstrating a novel link between protoporphyrinogen oxidase (HemG) and Chlamydia trachomatis infectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.855199

Lactoferrin disruption of bacterial type III secretion systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.855199

Emerging resistance in Gram-negative pathogens and implications for clinical practice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.855199

A refined model of the prototypical Salmonella SPI-1 T3SS basal body reveals the molecular basis for its assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.855199

Structural insights into the assembly of the type III secretion needle complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.855199

Three-dimensional model of Salmonella's needle complex at subnanometer resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.855199

Regulation of the Yersinia type III secretion system: traffic control

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.855199

EspZ of enteropathogenic and enterohemorrhagic Escherichia coli regulates type III secretion system protein translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.855199

Structural insights into host GTPase isoform selection by a family of bacterial GEF mimics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.855199

Evaluation of immunogenicity and protective efficacy of orally delivered Shigella type III secretion system proteins IpaB and IpaD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.855199

Decreased shedding of Escherichia coli O157:H7 by cattle following vaccination with type III secreted proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.855199

10.1517/14728222.2014.855199

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24295327%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

1 reference