(Q38168708)

30 August 2017

title

BAG-6, a jack of all trades in health and disease (English)

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30 August 2017

Janina Binici

1

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30 August 2017

Joachim Koch

series ordinal

2

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30 August 2017

publication date

4 December 2013

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Cellular and Molecular Life Sciences

30 August 2017

published in

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30 August 2017

volume

71

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30 August 2017

issue

10

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30 August 2017

page(s)

1829-1837

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A gene pair from the human major histocompatibility complex encodes large proline-rich proteins with multiple repeated motifs and a single ubiquitin-like domain

30 August 2017

cites work

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21 January 2018

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Scythe regulates apoptosis through modulating ubiquitin-mediated proteolysis of the Xenopus elongation factor XEF1AO.

21 January 2018

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Unique proteasome subunit Xrpn10c is a specific receptor for the antiapoptotic ubiquitin-like protein Scythe

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Ricin triggers apoptotic morphological changes through caspase-3 cleavage of BAT3

21 January 2018

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Scythe cleavage during Fas (APO-1)-and staurosporine-mediated apoptosis

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Scythe regulates apoptosis-inducing factor stability during endoplasmic reticulum stress-induced apoptosis

21 January 2018

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The reaper-binding protein scythe modulates apoptosis and proliferation during mammalian development

21 January 2018

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HLA-B-associated transcript 3 (Bat3)/Scythe is essential for p300-mediated acetylation of p53

21 January 2018

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Human Scythe contains a functional nuclear localization sequence and remains in the nucleus during staurosporine-induced apoptosis

21 January 2018

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Regulation of apoptosis by Bat3-enhanced YWK-II/APLP2 protein stability.

21 January 2018

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Nuclear BAG6-UBL4A-GET4 complex mediates DNA damage signaling and cell death.

21 January 2018

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BAT3 and SET1A form a complex with CTCFL/BORIS to modulate H3K4 histone dimethylation and gene expression

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1522-Y

Bat3 facilitates H3K79 dimethylation by DOT1L and promotes DNA damage-induced 53BP1 foci at G1/G2 cell-cycle phases

21 January 2018

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A novel BAT3 sequence generated by alternative RNA splicing of exon 11B displays cell type-specific expression and impacts on subcellular localization

21 January 2018

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A ubiquitin ligase-associated chaperone holdase maintains polypeptides in soluble states for proteasome degradation

21 January 2018

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Human leukocyte antigen-B-associated transcript 3 is released from tumor cells and engages the NKp30 receptor on natural killer cells

21 January 2018

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Dendritic cells release HLA-B-associated transcript-3 positive exosomes to regulate natural killer function

21 January 2018

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Activating natural cytotoxicity receptors of natural killer cells in cancer and infection

21 January 2018

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Reversible inhibition of Hsp70 chaperone function by Scythe and Reaper

21 January 2018

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Sequential interplay between BAG6 and HSP70 upon heat shock

21 January 2018

1 reference

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Bat3 deficiency accelerates the degradation of Hsp70-2/HspA2 during spermatogenesis

21 January 2018

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Molecular chaperone targeting and regulation by BAG family proteins

21 January 2018

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What's in the 'BAG'?--A functional domain analysis of the BAG-family proteins.

21 January 2018

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BAG-1 accelerates cell motility of human gastric cancer cells

21 January 2018

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BAG3: a multifaceted protein that regulates major cell pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1522-Y

The anti-apoptotic protein BAG-3 is overexpressed in pancreatic cancer and induced by heat stress in pancreatic cancer cell lines

21 January 2018

1 reference

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Biogenesis of tail-anchored proteins: the beginning for the end?

21 January 2018

1 reference

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Identification of a targeting factor for posttranslational membrane protein insertion into the ER

21 January 2018

1 reference

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The GET complex mediates insertion of tail-anchored proteins into the ER membrane

21 January 2018

1 reference

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Crystal Structure of Get4-Get5 Complex and Its Interactions with Sgt2, Get3, and Ydj1

21 January 2018

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The mechanism of membrane-associated steps in tail-anchored protein insertion

21 January 2018

1 reference

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A ribosome-associating factor chaperones tail-anchored membrane proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1522-Y

Bat3 promotes the membrane integration of tail-anchored proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1522-Y

SGTA recognizes a noncanonical ubiquitin-like domain in the Bag6-Ubl4A-Trc35 complex to promote endoplasmic reticulum-associated degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1522-Y

BAG-6 is essential for selective elimination of defective proteasomal substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1522-Y

Degradation of a cytosolic protein requires endoplasmic reticulum-associated degradation machinery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1522-Y

The macromolecular peptide-loading complex in MHC class I-dependent antigen presentation

21 January 2018

1 reference

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Protein targeting and degradation are coupled for elimination of mislocalized proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1522-Y

The ubiquitylation machinery of the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1522-Y

BAT3 guides misfolded glycoproteins out of the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1522-Y

BAT3 interacts with transforming growth factor-beta (TGF-beta) receptors and enhances TGF-beta1-induced type I collagen expression in mesangial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1522-Y

E3 ubiquitin ligase activity and targeting of BAT3 by multiple Legionella pneumophila translocated substrates

21 January 2018

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Common 5p15.33 and 6p21.33 variants influence lung cancer risk

21 January 2018

1 reference

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Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1522-Y

Human lymphocyte antigen B-associated transcript 2, 3, and 5 polymorphisms and haplotypes are associated with susceptibility of Kawasaki disease and coronary artery aneurysm.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1522-Y

Pleiotropic effects of the 8.1 HLA haplotype in patients with autoimmune myasthenia gravis and thymus hyperplasia

21 January 2018

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Identifying candidate colon cancer tumor suppressor genes using inhibition of nonsense-mediated mRNA decay in colon cancer cells

21 January 2018

1 reference

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Bat3 promotes T cell responses and autoimmunity by repressing Tim-3–mediated cell death and exhaustion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1522-Y

γ-Interferon-regulated chaperone governs human lymphocyte antigen class II expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1522-Y

BAT3 regulates Mycobacterium tuberculosis protein ESAT-6-mediated apoptosis of macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1522-Y

The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1522-Y

The ESAT6 protein of Mycobacterium tuberculosis induces apoptosis of macrophages by activating caspase expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1522-Y

Loss of phospholipid asymmetry and surface exposure of phosphatidylserine is required for phagocytosis of apoptotic cells by macrophages and fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1522-Y

A role for oxidative stress in apoptosis: oxidation and externalization of phosphatidylserine is required for macrophage clearance of cells undergoing Fas-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1522-Y

AIF and Scythe (Bat3) regulate phosphatidylserine exposure and macrophage clearance of cells undergoing Fas (APO-1)-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1522-Y

Mechanisms of tumor and viral immune escape from natural killer cell-mediated surveillance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1522-Y

Soluble ligands for NK cell receptors promote evasion of chronic lymphocytic leukemia cells from NK cell anti-tumor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1522-Y

Rescue of impaired NK cell activity in hodgkin lymphoma with bispecific antibodies in vitro and in patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1522-Y

Differential mechanisms of shedding of the glycosylphosphatidylinositol (GPI)-anchored NKG2D ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1522-Y

Natural killer cell cytotoxicity is suppressed by exposure to the human NKG2D ligand MICA*008 that is shed by tumor cells in exosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1522-Y

Ceramide triggers budding of exosome vesicles into multivesicular endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1522-Y

New prospects on the NKG2D/NKG2DL system for oncology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1522-Y

A ubiquitin-like domain recruits an oligomeric chaperone to a retrotranslocation complex in endoplasmic reticulum-associated degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1522-Y

Fine mapping of the MHC Class III region demonstrates association of AIF1 and rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1522-Y

The major substrates for TAP in vivo are derived from newly synthesized proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1522-Y

Regulation of class II MHC expression in APCs: roles of types I, III, and IV class II transactivator

21 January 2018

1 reference

12 December 2020

A soluble fragment of the tumor antigen BCL2-associated athanogene 6 (BAG-6) is essential and sufficient for inhibition of NKp30 receptor-dependent cytotoxicity of natural killer cells

1 reference

12 December 2020

Ancestral haplotypes reveal the role of the central MHC in the immunogenetics of IDDM

1 reference

12 December 2020

Expression of BAG-1 in invasive breast carcinomas

1 reference

12 December 2020

Human SGT interacts with Bag-6/Bat-3/Scythe and cells with reduced levels of either protein display persistence of few misaligned chromosomes and mitotic arrest

1 reference

12 December 2020

The interaction between NK cells and dendritic cells in bacterial infections results in rapid induction of NK cell activation and in the lysis of uninfected dendritic cells

1 reference

12 December 2020

Cutting edge: neosynthesis is required for the presentation of a T cell epitope from a long-lived viral protein

1 reference

12 December 2020

10.1007/S00018-013-1522-Y

Identifiers

DOI

1 reference

30 August 2017

1 reference