(Q38169563)

30 August 2017

The EGFR signalling system in the liver: from hepatoprotection to hepatocarcinogenesis (English)

1 reference

30 August 2017

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24318021%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Matias Avila

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24318021%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

author name string

Carmen Berasain

series ordinal

1

1 reference

30 August 2017

Matías A Avila

series ordinal

2

1 reference

30 August 2017

language of work or name

1 reference

10 December 2013

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Journal of Gastroenterology

30 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24318021%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

volume

49

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24318021%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24318021%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

page(s)

9-23

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New agents on the horizon in hepatocellular carcinoma

10 June 2020

cites work

1 reference

12 December 2020

Effects of platelet-derived growth factor and other polypeptide mitogens on DNA synthesis and growth of cultured rat liver fat-storing cells

1 reference

12 December 2020

Mutant epidermal growth factor receptor (EGFRvIII) contributes to head and neck cancer growth and resistance to EGFR targeting

1 reference

12 December 2020

Transforming growth factor-alpha and epidermal growth factor receptor in chronic liver disease and hepatocellular carcinoma

1 reference

12 December 2020

Secreted ERBB3 isoforms are serum markers for early hepatoma in patients with chronic hepatitis and cirrhosis.

1 reference

12 December 2020

Mouse model of carbon tetrachloride induced liver fibrosis: Histopathological changes and expression of CD133 and epidermal growth factor

1 reference

12 December 2020

Amphiregulin, an epidermal growth factor receptor ligand, plays an essential role in the pathogenesis of transforming growth factor-β-induced pulmonary fibrosis

1 reference

12 December 2020

Connective tissue growth factor autocriny in human hepatocellular carcinoma: oncogenic role and regulation by epidermal growth factor receptor/yes-associated protein-mediated activation

1 reference

12 December 2020

Phase 2 study of erlotinib in patients with unresectable hepatocellular carcinoma

1 reference

12 December 2020

Dysregulation of growth factor signaling in human hepatocellular carcinoma.

1 reference

12 December 2020

Association between nonalcoholic fatty liver disease and risk for hepatocellular cancer, based on systematic review

1 reference

12 December 2020

EGFR: A Master Piece in G1/S Phase Transition of Liver Regeneration

1 reference

12 December 2020

Molecular mechanisms of resistance to the EGFR monoclonal antibody cetuximab

1 reference

12 December 2020

Cytokines and cellular crosstalk involved in the activation of fat-storing cells.

1 reference

12 December 2020

Gemcitabine plus oxaliplatin (GEMOX) combined with cetuximab in patients with progressive advanced stage hepatocellular carcinoma: results of a multicenter phase 2 study

1 reference

12 December 2020

ZD1839, a selective epidermal growth factor receptor tyrosine kinase inhibitor, shows antimetastatic activity using a hepatocellular carcinoma model.

1 reference

12 December 2020

The epidermal growth factor receptor ligand amphiregulin is a negative regulator of hepatic acute-phase gene expression.

1 reference

12 December 2020

A phase II study of lapatinib in patients with advanced biliary tree and hepatocellular cancer

1 reference

12 December 2020

Targeting EGFR resistance networks in head and neck cancer.

1 reference

12 December 2020

Pivotal role of mTOR signaling in hepatocellular carcinoma

1 reference

12 December 2020

Prevention of hepatocellular carcinoma: potential targets, experimental models, and clinical challenges

1 reference

12 December 2020

Role of the microenvironment in the pathogenesis and treatment of hepatocellular carcinoma

1 reference

12 December 2020

Gene expression in fixed tissues and outcome in hepatocellular carcinoma.

1 reference

12 December 2020

Rethinking future development of molecular therapies in hepatocellular carcinoma: a bottom-up approach.

1 reference

12 December 2020

Emerging targeted strategies in advanced hepatocellular carcinoma

1 reference

12 December 2020

GH Receptor Plays a Major Role in Liver Regeneration through the Control of EGFR and ERK1/2 Activation

1 reference

12 December 2020

Amphiregulin: a new growth factor in hepatocarcinogenesis.

1 reference

12 December 2020

Understanding resistance to EGFR inhibitors-impact on future treatment strategies

1 reference

12 December 2020

Heparin-binding epidermal growth factor-like growth factor links hepatocyte priming with cell cycle progression during liver regeneration

1 reference

12 December 2020

Targeting MET as a strategy to overcome crosstalk-related resistance to EGFR inhibitors

1 reference

12 December 2020

The major vault protein mediates resistance to epidermal growth factor receptor inhibition in human hepatoma cells

1 reference

12 December 2020

Amphiregulin contributes to the transformed phenotype of human hepatocellular carcinoma cells.

1 reference

12 December 2020

Landscape of EGFR signaling network in human cancers: biology and therapeutic response in relation to receptor subcellular locations

1 reference

12 December 2020

New molecular targets for hepatocellular carcinoma: the ErbB1 signaling system

1 reference

12 December 2020

Nuclear EGFR as a molecular target in cancer

1 reference

12 December 2020

Increased expression of epidermal growth factor receptor (EGF-R) in patients with different forms of lung fibrosis

1 reference

12 December 2020

Mitogen-inducible gene-6 is a negative regulator of epidermal growth factor receptor signaling in hepatocytes and human hepatocellular carcinoma

1 reference

12 December 2020

Inhibition of CIP2A determines erlotinib-induced apoptosis in hepatocellular carcinoma

1 reference

12 December 2020

The epidermal growth factor receptor ligand amphiregulin participates in the development of mouse liver fibrosis.

1 reference

12 December 2020

Sex bias occurrence of hepatocellular carcinoma in Poly7 molecular subclass is associated with EGFR.

1 reference

12 December 2020

The multiple roles of amphiregulin in human cancer.

1 reference

12 December 2020

Expression of transforming growth factor alpha and epidermal growth factor receptor in human hepatocellular carcinoma

1 reference

12 December 2020

Integrin-linked kinase overexpression and its oncogenic role in promoting tumorigenicity of hepatocellular carcinoma

1 reference

12 December 2020

Expression of epidermal growth factor and its receptor in cirrhotic liver disease

1 reference

12 December 2020

Epithelial-to-mesenchymal transition and integrin-linked kinase mediate sensitivity to epidermal growth factor receptor inhibition in human hepatoma cells.

1 reference

12 December 2020

Neuregulin/erythroblastic leukemia viral oncogene homolog 3 autocrine loop contributes to invasion and early recurrence of human hepatoma

1 reference

12 December 2020

Erlotinib induces cell cycle arrest and apoptosis in hepatocellular cancer cells and enhances chemosensitivity towards cytostatics

1 reference

12 December 2020

[Expression and significance of epidermal growth factor receptor variant type III in hepatocellular carcinoma]

1 reference

12 December 2020

Conditional loss of heparin-binding EGF-like growth factor results in enhanced liver fibrosis after bile duct ligation in mice

1 reference

12 December 2020

Ectodomain shedding of EGFR ligands and TNFR1 dictates hepatocyte apoptosis during fulminant hepatitis in mice

1 reference

12 December 2020

Growth suppression of human hepatocellular carcinoma xenografts by a monoclonal antibody CH12 directed to epidermal growth factor receptor variant III

1 reference

12 December 2020

Gefitinib, an EGFR inhibitor, prevents hepatocellular carcinoma development in the rat liver with cirrhosis

1 reference

12 December 2020

Signaling cross-talk in the resistance to HER family receptor targeted therapy

1 reference

12 December 2020

Expression and clinical significance of erb-B receptor family in hepatocellular carcinoma

1 reference

12 December 2020

Blockage of epidermal growth factor receptor by quinazoline tyrosine kinase inhibitors suppresses growth of human hepatocellular carcinoma

1 reference

12 December 2020

Amphiregulin promotes BAX inhibition and resistance to gefitinib in non-small-cell lung cancers.

1 reference

12 December 2020

Epidemiology of hepatocellular carcinoma: consider the population

1 reference

12 December 2020

Targeting ERBB receptors shifts their partners and triggers persistent ERK signaling through a novel ERBB/EFNB1 complex

1 reference

12 December 2020

Induction of DNA synthesis in primary mouse hepatocytes is associated with nuclear pro-transforming growth factor alpha and erbb-1 and is independent of c-jun

1 reference

12 December 2020

Expression of Wilms' tumor suppressor in the liver with cirrhosis: relation to hepatocyte nuclear factor 4 and hepatocellular function

1 reference

12 December 2020

Phase II study of Erlotinib (OSI-774) in patients with advanced hepatocellular cancer

1 reference

12 December 2020

EGFRvIII mRNA detection in the serum of patients with hepatocellular carcinoma

1 reference

12 December 2020

NF-kappaB activation in non-parenchymal liver cells after partial hepatectomy in rats: possible involvement in expression of heparin-binding epidermal growth factor-like growth factor.

1 reference

12 December 2020

HGF induces novel EGFR functions involved in resistance formation to tyrosine kinase inhibitors

1 reference

12 December 2020

Phase 2 study of bevacizumab plus erlotinib in patients with advanced hepatocellular cancer

1 reference

12 December 2020

Impact of IGF-1R/EGFR cross-talks on hepatoma cell sensitivity to gefitinib

1 reference

12 December 2020

Induction of renal fibrotic genes by TGF-β1 requires EGFR activation, p53 and reactive oxygen species.

1 reference

12 December 2020

Long distance calling for liver regeneration: identification of neuroendocrine signalling pathways activated after partial hepatectomy

1 reference

12 December 2020

RNA interference against hepatic epidermal growth factor receptor has suppressive effects on liver regeneration in rats

1 reference

12 December 2020

The EGF receptor is required for efficient liver regeneration

1 reference

12 December 2020

Regulation of amphiregulin gene expression by β-catenin signaling in human hepatocellular carcinoma cells: a novel crosstalk between FGF19 and the EGFR system

1 reference

12 December 2020

Met as a therapeutic target in HCC: facts and hopes.

1 reference

12 December 2020

The monoclonal antibody CH12 enhances the sorafenib-mediated growth inhibition of hepatocellular carcinoma xenografts expressing epidermal growth factor receptor variant III

1 reference

12 December 2020

Cross-talk between epidermal growth factor receptor and c-Met signal pathways in transformed cells

1 reference

12 December 2020

Conditional deletion of beta-catenin reveals its role in liver growth and regeneration

1 reference

12 December 2020

Potential for molecularly targeted therapy against epidermal growth factor receptor ligands.

1 reference

12 December 2020

Liver fibrosis: insights into migration of hepatic stellate cells in response to extracellular matrix and growth factors

1 reference

12 December 2020

EGFR and VEGFR as potential target for biological therapies in HCC cells.

1 reference

12 December 2020

EGFR blockade by cetuximab alone or as combination therapy for growth control of hepatocellular cancer

1 reference

12 December 2020

Epidermal growth factor receptor vIII enhances tumorigenicity and resistance to 5-fluorouracil in human hepatocellular carcinoma

1 reference

12 December 2020

Bevacizumab with erlotinib as first-line therapy in Asian patients with advanced hepatocellular carcinoma: a multicenter phase II study

1 reference

12 December 2020

The monoclonal antibody CH12 augments 5-fluorouracil-induced growth suppression of hepatocellular carcinoma xenografts expressing epidermal growth factor receptor variant III.

1 reference

12 December 2020

The inhibition of the epidermal growth factor (EGF) pathway enhances TGF-beta-induced apoptosis in rat hepatoma cells through inducing oxidative stress coincident with a change in the expression pattern of the NADPH oxidases (NOX) isoforms

1 reference

12 December 2020

Genetic or pharmacologic blockade of EGFR inhibits renal fibrosis.

1 reference

12 December 2020

Hepatocyte growth factor, transforming growth factor alpha, and their receptors as combined markers of prognosis in hepatocellular carcinoma

1 reference

12 December 2020

Phase II trial of the combination of bevacizumab and erlotinib in patients who have advanced hepatocellular carcinoma.

1 reference

12 December 2020

Down-regulation of connective tissue growth factor by inhibition of transforming growth factor beta blocks the tumor-stroma cross-talk and tumor progression in hepatocellular carcinoma.

1 reference

12 December 2020

Cellular and molecular mechanisms of hepatocellular carcinoma: an update

1 reference

12 December 2020

Epidermal growth factor receptor and HER-3 restrict cell response to sorafenib in hepatocellular carcinoma cells.

1 reference

12 December 2020

Targeted therapies for hepatocellular carcinoma.

1 reference

12 December 2020

Conditional knockout of heparin-binding epidermal growth factor-like growth factor in the liver accelerates carbon tetrachloride-induced liver injury in mice

1 reference

12 December 2020

Ubiquitous activation of Ras and Jak/Stat pathways in human HCC.

1 reference

12 December 2020

Translocation of epidermal growth factor to the hepatocyte nucleus during rat liver regeneration

1 reference

12 December 2020

Expression of betacellulin and epidermal growth factor receptor in hepatocellular carcinoma: implications for angiogenesis

1 reference

12 December 2020

MUC15 inhibits dimerization of EGFR and PI3K-AKT signaling and is associated with aggressive hepatocellular carcinomas in patients

1 reference

12 December 2020

Sustained activation of EGFR triggers renal fibrogenesis after acute kidney injury

1 reference

12 December 2020

Eph receptor signaling and ephrins

1 reference

12 December 2020

Advanced unresectable hepatocellular carcinoma: new biologics as fresh ammunition or clues to disease understanding?

1 reference

12 December 2020

Expression of ephrin-B1 in hepatocellular carcinoma: possible involvement in neovascularization.

1 reference

12 December 2020

Liver regeneration and hepatocarcinogenesis in transforming growth factor-alpha-targeted mice.

1 reference

12 December 2020

Immunotherapy of hepatocellular carcinoma: Unique challenges and clinical opportunities

1 reference

12 December 2020

1 reference

12 December 2020

Amphiregulin stimulates liver regeneration after small-for-size mouse liver transplantation.

1 reference

12 December 2020

Dual targeting of EGFR and HER3 with MEHD7945A overcomes acquired resistance to EGFR inhibitors and radiation

1 reference

12 December 2020

Fibrosis-dependent mechanisms of hepatocarcinogenesis

1 reference

12 December 2020

Epidermal growth factor receptor expression and gene copy number in conventional hepatocellular carcinoma

1 reference

12 December 2020

New therapies for hepatocellular carcinoma.

1 reference

12 December 2020

Targeting the ERBB family in cancer: couples therapy

1 reference

12 December 2020

Laminin-5 stimulates hepatocellular carcinoma growth through a different function of alpha6beta4 and alpha3beta1 integrins.

1 reference

12 December 2020

Hepatocellular carcinoma

1 reference

12 December 2020

Laminin-5 offsets the efficacy of gefitinib ('Iressa') in hepatocellular carcinoma cells.

1 reference

12 December 2020

Reduced mRNA abundance of the main enzymes involved in methionine metabolism in human liver cirrhosis and hepatocellular carcinoma

1 reference

12 December 2020

Amphiregulin enhances regulatory T cell-suppressive function via the epidermal growth factor receptor.

1 reference

12 December 2020

Localization of epidermal growth factor receptor in hepatocyte nuclei

1 reference

12 December 2020

The inflammatory microenvironment in hepatocellular carcinoma: a pivotal role for tumor-associated macrophages

1 reference

12 December 2020

Inhibition of the EGF receptor blocks autocrine growth and increases the cytotoxic effects of doxorubicin in rat hepatoma cells: role of reactive oxygen species production and glutathione depletion

1 reference

12 December 2020

Nuclear α1-antichymotrypsin promotes chromatin condensation and inhibits proliferation of human hepatocellular carcinoma cells.

1 reference

12 December 2020

Genetic characterization of fas-associated phosphatase-1 as a putative tumor suppressor gene on chromosome 4q21.3 in hepatocellular carcinoma

1 reference

12 December 2020

Amphiregulin induces the alternative splicing of p73 into its oncogenic isoform DeltaEx2p73 in human hepatocellular tumors.

1 reference

12 December 2020

Molecular pathways: the complex roles of inflammation pathways in the development and treatment of liver cancer.

1 reference

12 December 2020

10.1007/S00535-013-0907-X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24318021%20AND%20SRC:MED&resulttype=core&format=json

release_6hr3ivmajfgttp3ctvtewjnb34

10 June 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/6hr3ivmajfgttp3ctvtewjnb34

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24318021%20AND%20SRC:MED&resulttype=core&format=json