(Q37183244)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18929564%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

title

Pivotal role of mTOR signaling in hepatocellular carcinoma (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18929564%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

main subject

hepatocellular carcinoma

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18929564%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

Derek Y Chiang

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18929564%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

Beatriz Mínguez

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18929564%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

Vincenzo Mazzaferro

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18929564%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

Jordi Bruix

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18929564%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

Josep M. Llovet

26

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18929564%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

22

Samuel Waxman

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18929564%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

23

Myron Schwartz

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18929564%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

15

Yujin Hoshida

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18929564%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

7

Victoria Tovar

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18929564%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

6

Clara Alsinet

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18929564%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

5

Swan Thung

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18929564%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

8

Sasan Roayaie

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18929564%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

17

Sara Toffanin

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18929564%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

4

Judit Peix

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18929564%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

11

Carlo Battiston

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18929564%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

16

Steven Yea

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18929564%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

19

John A Martignetti

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18929564%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

24

Matthew Meyerson

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18929564%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

author name string

Pippa Newell

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18929564%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

Manel Sole

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18929564%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

Stijn Van Laarhoven

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18929564%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

Maria I Fiel

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18929564%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

Analisa Di Feo

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18929564%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

Alex Ramos

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18929564%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

Scott L Friedman

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18929564%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

language of work or name

English

0 references

publication date

20 August 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18929564%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18929564%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

volume

135

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18929564%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18929564%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

page(s)

1972-83, 1983.e1-11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18929564%20AND%20SRC:MED&resulttype=core&format=json

Molecular targeted therapies in hepatocellular carcinoma

24 December 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678688

Focal gains of VEGFA and molecular classification of hepatocellular carcinoma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678688

Sorafenib in advanced hepatocellular carcinoma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678688

Design and endpoints of clinical trials in hepatocellular carcinoma.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678688

Genomics and signaling pathways in hepatocellular carcinoma.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678688

Rapamycin derivatives reduce mTORC2 signaling and inhibit AKT activation in AML.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678688

A molecular signature to discriminate dysplastic nodules from early hepatocellular carcinoma in HCV cirrhosis.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678688

Systematic review: evidence-based management of hepatocellular carcinoma--an updated analysis of randomized controlled trials.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678688

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678688

Exploiting the PI3K/AKT pathway for cancer drug discovery

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678688

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678688

Expression of albumin, IGF-1, IGFBP-3 in tumor tissues and adjacent non-tumor tissues of hepatocellular carcinoma patients with cirrhosis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678688

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678688

Methylation profile of the promoter CpG islands of 31 genes that may contribute to colorectal carcinogenesis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678688

Hepatocellular carcinoma in cirrhosis: incidence and risk factors

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678688

The TOR pathway: a target for cancer therapy

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678688

Increased survival of cirrhotic patients with a hepatocellular carcinoma detected during surveillance

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678688

6 September 2017

Hepatocellular carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678688

The phosphatidylinositol 3-Kinase AKT pathway in human cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678688

Growth-suppressive effects of BPOZ and EGR2, two genes involved in the PTEN signaling pathway.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678688

Significance analysis of microarrays applied to the ionizing radiation response

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678688

Isolation of transforming murine leukemia viruses from mice with a high incidence of spontaneous lymphoma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678688

mTORC2 activity is elevated in gliomas and promotes growth and cell motility via overexpression of rictor

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678688

Vascular remodeling and antitumoral effects of mTOR inhibition in a rat model of hepatocellular carcinoma

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678688

Mammalian target of rapamycin pathway activity in hepatocellular carcinomas of patients undergoing liver transplantation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678688

Sirolimus inhibits growth of human hepatoma cells alone or combined with tacrolimus, while tacrolimus promotes cell growth

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678688

Genome-wide molecular profiles of HCV-induced dysplasia and hepatocellular carcinoma

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678688

PRR5, a novel component of mTOR complex 2, regulates platelet-derived growth factor receptor beta expression and signaling.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678688

Dysfunctional AMPK activity, signalling through mTOR and survival in response to energetic stress in LKB1-deficient lung cancer.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678688

mTOR and P70 S6 kinase expression in primary liver neoplasms

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678688

PIK3CA gene is frequently mutated in breast carcinomas and hepatocellular carcinomas.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678688

Classification and prediction of survival in hepatocellular carcinoma by gene expression profiling

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678688

Expression and prognostic role of tumor suppressor gene PTEN/MMAC1/TEP1 in hepatocellular carcinoma

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678688

Risk factors contributing to early and late phase intrahepatic recurrence of hepatocellular carcinoma after hepatectomy.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678688

PTEN/MMAC1 mutations in hepatocellular carcinomas

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678688

The AKT-mTOR pathway plays a critical role in the development of leiomyosarcomas

3 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18929564

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Activation of the c-fos enhancer by the erk MAP kinase pathway through two sequence elements: the c-fos AP-1 and p62TCF sites

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18929564

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Absence of PIK3CA hotspot mutations in hepatocellular carcinoma in Japanese patients

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18929564

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1053/J.GASTRO.2008.08.008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18929564%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18929564%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

PubMed publication ID

18929564

1 reference