(Q38169989)

30 August 2017

title

Holomycin, a dithiolopyrrolone compound produced by Streptomyces clavuligerus (English)

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Streptomyces clavuligerus

30 August 2017

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Streptomyces coelicolor

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Streptomyces flavovirens

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Streptomyces katsurahamanus

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Streptomyces flavogriseus

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Streptomyces albidoflavus

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Streptomyces jumonjinensis

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N-{4-oxo-5H-[1,2]dithiolo[3,4-b]pyrrol-3-yl}ethanimidic acid

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Paloma Liras

1

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30 August 2017

language of work or name

English

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publication date

10 December 2013

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Applied Microbiology and Biotechnology

30 August 2017

published in

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30 August 2017

volume

98

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30 August 2017

issue

3

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30 August 2017

page(s)

1023-1030

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https://scigraph.springernature.com/pub.10.1007/s00253-013-5410-z

30 August 2017

exact match

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cites work

Exploiting adaptive laboratory evolution of Streptomyces clavuligerus for antibiotic discovery and overproduction

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-5410-Z

Expression of pyrrothine N-acyltransferase activities in Saccharothrix algeriensis NRRL B-24137: new insights into dithiolopyrrolone antibiotic biosynthetic pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-5410-Z

Avoidance of suicide in antibiotic-producing microbes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-5410-Z

Mutants of Streptomyces clavuligerus with disruptions in different genes for clavulanic acid biosynthesis produce large amounts of holomycin: possible cross-regulation of two unrelated secondary metabolic pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-5410-Z

A natural plasmid uniquely encodes two biosynthetic pathways creating a potent anti-MRSA antibiotic

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-5410-Z

Thiolutin inhibits endothelial cell adhesion by perturbing Hsp27 interactions with components of the actin and intermediate filament cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-5410-Z

Mode of Action of Thiolutin, an Inhibitor of Macromolecular Synthesis in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-5410-Z

Identification of the gene cluster for the dithiolopyrrolone antibiotic holomycin in Streptomyces clavuligerus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-5410-Z

Streptomyces clavuligerus HlmI is an intramolecular disulfide-forming dithiol oxidase in holomycin biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-5410-Z

Expansion of the clavulanic acid gene cluster: identification and in vivo functional analysis of three new genes required for biosynthesis of clavulanic acid by Streptomyces clavuligerus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-5410-Z

Substituted 6-amino-4H-[1,2]dithiolo[4,3-b]pyrrol-5-ones: synthesis, structure-activity relationships, and cytotoxic activity on selected human cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-5410-Z

A backup plan for self-protection: S-methylation of holomycin biosynthetic intermediates in Streptomyces clavuligerus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-5410-Z

Two oligopeptide-permease-encoding genes in the clavulanic acid cluster of Streptomyces clavuligerus are essential for production of the beta-lactamase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-5410-Z

Biologically active metabolites from Xenorhabdus spp., Part 1. Dithiolopyrrolone derivatives with antibiotic activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-5410-Z

A rhodanese-like protein is highly overrepresented in the mutant S. clavuligerus oppA2::aph: effect on holomycin and other secondary metabolites production

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-5410-Z

RNA polymerase inhibitors with activity against rifampin-resistant mutants of Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-5410-Z

Antimicrobial properties and mode of action of the pyrrothine holomycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-5410-Z

The transcriptional inhibitor thiolutin blocks mRNA degradation in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-5410-Z

The fish pathogen Yersinia ruckeri produces holomycin and uses an RNA methyltransferase for self-resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-5410-Z

Transcriptional analysis and proteomics of the holomycin gene cluster in overproducer mutants of Streptomyces clavuligerus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-5410-Z

Antibacterial compounds from marine Vibrionaceae isolated on a global expedition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-5410-Z

Induction of holomycin production and complex metabolic changes by the argR mutation in Streptomyces clavuligerus NP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-5410-Z

Engineered Thiomarinol Antibiotics Active against MRSA Are Generated by Mutagenesis and Mutasynthesis of Pseudoalteromonas SANK73390

21 January 2018

1 reference

9 March 2024

https://opencitations.net/index/api/v1/citations/10.1002/ANIE.201007029

New dithiolopyrrolone antibiotics from Saccharothrix sp. SA 233. II. Physicochemical properties and structure elucidation.

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.55.702

New dithiolopyrrolone antibiotics from Saccharothrix sp. SA 233. I. Taxonomy, fermentation, isolation and biological activities.

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.55.696

Thiomarinol, a new hybrid antimicrobial antibiotic produced by a marine bacterium. Fermentation, isolation, structure, and antimicrobial activity.

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.46.1834

Holomycin and N-propionylholothin, antibiotics produced by a cephamycin C producer

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.30.334

Identifiers

DOI

10.1007/S00253-013-5410-Z

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Dimensions Publication ID

30 August 2017

1020144209

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