(Q38174578)

30 August 2017

title

Recent structural and functional insights into the family of sodium calcium exchangers (English)

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30 August 2017

Vishal Sharma

1

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30 August 2017

Damien M O'Halloran

series ordinal

2

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30 August 2017

publication date

27 December 2013

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30 August 2017

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30 August 2017

volume

52

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30 August 2017

issue

2

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30 August 2017

page(s)

93-109

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Residues contributing to the Na(+)-binding pocket of the SLC24 Na(+)/Ca(2+)-K(+) Exchanger NCKX2.

30 August 2017

cites work

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Mitochondria recycle Ca(2+) to the endoplasmic reticulum and prevent the depletion of neighboring endoplasmic reticulum regions

21 January 2018

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The influence of calcium on sodium efflux in squid axons

21 January 2018

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Altered calcium homeostasis and mitochondrial dysfunction in cortical synaptic compartments of presenilin-1 mutant mice

21 January 2018

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Barbiturates block sodium and potassium conductance increases in voltage-clamped lobster axons

21 January 2018

1 reference

New roles of NCX in glial cells: activation of microglia in ischemia and differentiation of oligodendrocytes

21 January 2018

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Silencing or knocking out the Na(+)/Ca(2+) exchanger-3 (NCX3) impairs oligodendrocyte differentiation.

21 January 2018

1 reference

NCX1 expression and functional activity increase in microglia invading the infarct core

21 January 2018

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The cation/Ca(2+) exchanger superfamily: phylogenetic analysis and structural implications

21 January 2018

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Molecular cloning of a sixth member of the K+-dependent Na+/Ca2+ exchanger gene family, NCKX6

21 January 2018

1 reference

The release of calcium from heart mitochondria by sodium.

21 January 2018

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Role of the mitochondrial sodium/calcium exchanger in neuronal physiology and in the pathogenesis of neurological diseases

21 January 2018

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Extrusion of calcium from rod outer segments is driven by both sodium and potassium gradients.

21 January 2018

1 reference

Regional genomic regulation of cardiac sodium-calcium exchanger by oestrogen.

21 January 2018

1 reference

Antagonistic pathways in neurons exposed to body fluid regulate social feeding in Caenorhabditis elegans

21 January 2018

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Calcium signaling in brain mitochondria: interplay of malate aspartate NADH shuttle and calcium uniporter/mitochondrial dehydrogenase pathways

21 January 2018

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Molecular changes in neurons in multiple sclerosis: altered axonal expression of Nav1.2 and Nav1.6 sodium channels and Na+/Ca2+ exchanger

21 January 2018

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The Interrelations between the Transport of Sodium and Calcium in Mitochondria of Various Mammalian Tissues

21 January 2018

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Gene expression changes related to growth and differentiation in the fetal and juvenile reproductive system of the female rat: evaluation of microarray results

21 January 2018

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Electrophysiological characterization and ionic stoichiometry of the rat brain K(+)-dependent NA(+)/CA(2+) exchanger, NCKX2

21 January 2018

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Novel role for K+-dependent Na+/Ca2+ exchangers in regulation of cytoplasmic free Ca2+ and contractility in arterial smooth muscle

21 January 2018

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Molecular determinants of allosteric regulation in NCX proteins

21 January 2018

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Essential role of the CBD1-CBD2 linker in slow dissociation of Ca2+ from the regulatory two-domain tandem of NCX1.

21 January 2018

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G503 is obligatory for coupling of regulatory domains in NCX proteins.

21 January 2018

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SLC24A5 encodes a trans-Golgi network protein with potassium-dependent sodium-calcium exchange activity that regulates human epidermal melanogenesis

21 January 2018

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Mitochondrial localization of Na+/Ca2+ exchangers NCX1-3 in neurons and astrocytes of adult rat brain in situ

21 January 2018

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Role of Na/Ca exchange and the plasma membrane Ca2+-ATPase in beta cell function and death

21 January 2018

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Ca2+ regulation in the Na+/Ca2+ exchanger features a dual electrostatic switch mechanism

21 January 2018

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Charge movement during Na+ translocation by native and cloned cardiac Na+/Ca2+ exchanger.

21 January 2018

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From calcium signaling to cell death: two conformations for the mitochondrial permeability transition pore. Switching from low- to high-conductance state

21 January 2018

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Enhanced learning and memory in mice lacking Na+/Ca2+ exchanger 2

21 January 2018

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Signal sequence cleavage and plasma membrane targeting of the retinal rod NCKX1 and cone NCKX2 Na+/Ca2+ - K+ exchangers.

21 January 2018

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Residues contributing to the Ca2+ and K+ binding pocket of the NCKX2 Na+/Ca2+-K+ exchanger

21 January 2018

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Substitution of a single residue, Asp575, renders the NCKX2 K+-dependent Na+/Ca2+ exchanger independent of K+.

21 January 2018

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Multiple transport modes of the cardiac Na+/Ca2+ exchanger.

21 January 2018

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Cytoplasmic Na+-dependent modulation of mitochondrial Ca2+ via electrogenic mitochondrial Na+-Ca2+ exchange.

21 January 2018

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Pivotal role of mitochondrial Na⁺₋Ca²⁺ exchange in antigen receptor mediated Ca²⁺ signalling in DT40 and A20 B lymphocytes

21 January 2018

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Topology of the retinal cone NCKX2 Na/Ca-K exchanger.

21 January 2018

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Mitochondrial calcium ion and membrane potential transients follow the pattern of epileptiform discharges in hippocampal slice cultures.

21 January 2018

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Free radical-mediated cell damage after experimental status epilepticus in hippocampal slice cultures.

21 January 2018

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Molecular cloning of a third member of the potassium-dependent sodium-calcium exchanger gene family, NCKX3

21 January 2018

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SLC24A5, a putative cation exchanger, affects pigmentation in zebrafish and humans

21 January 2018

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Sodium-calcium exchangers in the nucleus: an unexpected locus and an unusual regulatory mechanism

21 January 2018

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KIF21A-mediated axonal transport and selective endocytosis underlie the polarized targeting of NCKX2.

21 January 2018

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Molecular cloning of a fourth member of the potassium-dependent sodium-calcium exchanger gene family, NCKX4

21 January 2018

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Importance of K+-dependent Na+/Ca2+-exchanger 2, NCKX2, in motor learning and memory

21 January 2018

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Structural insight into the ion-exchange mechanism of the sodium/calcium exchanger

21 January 2018

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beta-Adrenergic receptor stimulated Ncx1 upregulation is mediated via a CaMKII/AP-1 signaling pathway in adult cardiomyocytes

21 January 2018

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Mitochondrial nitric oxide mediates decreased vulnerability of hippocampal neurons from immature animals to NMDA.

21 January 2018

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Regulation of cardiac Na(+)-Ca2+ exchanger by the endogenous XIP region

21 January 2018

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Regulation of Ncx1 gene expression in the normal and hypertrophic heart

21 January 2018

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Na+ -Ca2+ exchanger (NCX3) knock-out mice display an impairment in hippocampal long-term potentiation and spatial learning and memory

21 January 2018

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Targeted disruption of Na+/Ca2+ exchanger 3 (NCX3) gene leads to a worsening of ischemic brain damage.

21 January 2018

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Cellular Ca2+ dynamics in urinary bladder smooth muscle from transgenic mice overexpressing Na+-Ca2+ exchanger

21 January 2018

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Cloning of a third mammalian Na+-Ca2+ exchanger, NCX3

21 January 2018

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Structural basis for the counter-transport mechanism of a H+/Ca2+ exchanger

21 January 2018

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C. elegans major fats are stored in vesicles distinct from lysosome-related organelles

21 January 2018

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Lithium-calcium exchange is mediated by a distinct potassium-independent sodium-calcium exchanger

21 January 2018

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NCLX is an essential component of mitochondrial Na+/Ca2+ exchange

21 January 2018

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A new concept: Aβ1-42 generates a hyperfunctional proteolytic NCX3 fragment that delays caspase-12 activation and neuronal death.

21 January 2018

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NCX1 and NCX3: two new effectors of delayed preconditioning in brain ischemia.

21 January 2018

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The NCX3 isoform of the Na+/Ca2+ exchanger contributes to neuroprotection elicited by ischemic postconditioning.

21 January 2018

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Multiple mechanisms of transmitter release evoked by "pathologically" elevated extracellular [K+]: involvement of transporter reversal and mitochondrial calcium.

21 January 2018

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Mechanisms of glutamate release elicited in rat cerebrocortical nerve endings by 'pathologically' elevated extraterminal K+ concentrations.

21 January 2018

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The topology of the cardiac Na⁺/Ca²⁺ exchanger, NCX1.

21 January 2018

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Plasmalemmal Na+/Ca2+ exchanger modulates Ca2+-dependent exocytotic release of glutamate from rat cortical astrocytes

21 January 2018

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Molecular and functional characterization of the human platelet Na(+) /Ca(2+) exchangers

21 January 2018

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Transient reversal of the sodium/calcium exchanger boosts presynaptic calcium and synaptic transmission at a cerebellar synapse

21 January 2018

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The cleaved N-terminal signal sequence of the cardiac Na(+)-Ca2+ exchanger is not required for functional membrane integration

21 January 2018

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Genes involved in implantation

21 January 2018

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NCX3 regulates mitochondrial Ca(2+) handling through the AKAP121-anchored signaling complex and prevents hypoxia-induced neuronal death

21 January 2018

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Insight into the family of Na+/Ca2+ exchangers of Caenorhabditis elegans

21 January 2018

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Na(+)-Ca(2+)-K(+) currents measured in insect cells transfected with the retinal cone or rod Na(+)-Ca(2+)-K(+) exchanger cDNA.

21 January 2018

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ERK1/2, p38, and JNK regulate the expression and the activity of the three isoforms of the Na+ /Ca2+ exchanger, NCX1, NCX2, and NCX3, in neuronal PC12 cells.

21 January 2018

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Anoxia-induced NF-kappaB-dependent upregulation of NCX1 contributes to Ca2+ refilling into endoplasmic reticulum in cortical neurons

21 January 2018

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High levels of synaptosomal Na(+)-Ca(2+) exchangers (NCX1, NCX2, NCX3) co-localized with amyloid-beta in human cerebral cortex affected by Alzheimer's disease

21 January 2018

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Mitochondrial involvement in post-tetanic potentiation of synaptic transmission

21 January 2018

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An SRF/miR-1 axis regulates NCX1 and annexin A5 protein levels in the normal and failing heart

21 January 2018

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NCX1 is a novel target gene for hypoxia-inducible factor-1 in ischemic brain preconditioning.

21 January 2018

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Exchangers NCKX2, NCKX3, and NCKX4: identification of Thr-551 as a key residue in defining the apparent K(+) affinity of NCKX2.

21 January 2018

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Structural basis for alternating access of a eukaryotic calcium/proton exchanger

21 January 2018

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Light activation, adaptation, and cell survival functions of the Na+/Ca2+ exchanger CalX.

21 January 2018

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Scanning mutagenesis of the alpha repeats and of the transmembrane acidic residues of the human retinal cone Na/Ca-K exchanger

21 January 2018

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Alzheimer's amyloid-beta peptide inhibits sodium/calcium exchange measured in rat and human brain plasma membrane vesicles

21 January 2018

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Regulation of Ncx1 expression. Identification of regulatory elements mediating cardiac-specific expression and up-regulation

21 January 2018

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Distinct expression of the calcium exchangers, NCKX3 and NCX1, and their regulation by steroid in the human endometrium during the menstrual cycle

21 January 2018

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Uterine expression of sodium/potassium/calcium exchanger 3 and its regulation by sex-steroid hormones during the estrous cycle of rats

21 January 2018

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Acute axonal injury in multiple sclerosis. Correlation with demyelination and inflammation

21 January 2018

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7 January 2021

Chronic hyperglycaemia increases neuronal sensitivity to high potassium in hippocampal slices from streptozotocin-treated diabetic rats

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7 January 2021

The role of GATA, CArG, E-box, and a novel element in the regulation of cardiac expression of the Na+-Ca2+ exchanger gene

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7 January 2021

Extrusion of Ca2+ from mouse motor terminal mitochondria via a Na+-Ca2+ exchanger increases post-tetanic evoked release

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7 January 2021

Ca2+ regulation in the Na+/Ca2+ exchanger involves two markedly different Ca2+ sensors

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7 January 2021

The sodium-calcium antiport of heart mitochondria is not electroneutral

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7 January 2021

Presynaptic localization of sodium/calcium exchangers in neuromuscular preparations

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7 January 2021

K+-dependent Na+/Ca2+ exchangers in the brain.

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7 January 2021

Cell-specific expression of SERCA, the exogenous Ca2+transport ATPase, in cardiac myocytes

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7 January 2021

Tissue specificity and alternative splicing of the Na+/Ca2+ exchanger isoforms NCX1, NCX2, and NCX3 in rat.

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7 January 2021

Functional regulation of alternatively spliced Na+/Ca2+ exchanger (NCX1) isoforms.

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7 January 2021

GM1 Ganglioside in the Nuclear Membrane Modulates Nuclear Calcium Homeostasis During Neurite Outgrowth

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7 January 2021

Identifiers

DOI

10.1002/DVG.22735

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30 August 2017

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