(Q38179183)

30 August 2017

title

Molecular mechanisms of congenital heart block (English)

1 reference

30 August 2017

0 references

Marie Wahren-Herlenius

series ordinal

3

object named as

Marie Wahren-Herlenius

0 references

author name string

Aurélie Ambrosi

series ordinal

1

1 reference

30 August 2017

Sven-Erik Sonesson

series ordinal

2

1 reference

30 August 2017

language of work or name

English

0 references

publication date

13 January 2014

1 reference

Experimental Cell Research

30 August 2017

published in

1 reference

30 August 2017

volume

325

1 reference

30 August 2017

issue

1

1 reference

30 August 2017

page(s)

2-9

1 reference

Autoimmune-associated congenital heart block: demographics, mortality, morbidity and recurrence rates obtained from a national neonatal lupus registry

30 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.01.003

Short- and long-term outcome of children with congenital complete heart block diagnosed in utero or as a newborn

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.01.003

Electrophysiological characteristics of fetal atrioventricular block

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.01.003

Maternal and fetal factors associated with mortality and morbidity in a multi-racial/ethnic registry of anti-SSA/Ro-associated cardiac neonatal lupus.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.01.003

Congenital complete heart block

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.01.003

Isolated congenital heart block. Long-term outcome of mothers and characterization of the immune response to SS-A/Ro and to SS-B/La

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.01.003

A serologic marker for fetal risk of congenital heart block

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.01.003

Risk of congenital complete heart block in newborns of mothers with anti-Ro/SSA antibodies detected by counterimmunoelectrophoresis: a prospective study of 100 women

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.01.003

Cloning and characterization of two human Ro52-specific monoclonal autoantibodies directed towards a domain associated with congenital heart block

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.01.003

Structurally derived mutations define congenital heart block-related epitopes within the 200-239 amino acid stretch of the Ro52 protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.01.003

Antibodies to amino acid 200-239 (p200) of Ro52 as serological markers for the risk of developing congenital heart block.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.01.003

The importance of the level of maternal anti-Ro/SSA antibodies as a prognostic marker of the development of cardiac neonatal lupus erythematosus a prospective study of 186 antibody-exposed fetuses and infants

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.01.003

Birth order, gender and recurrence rate in autoantibody-associated congenital heart block: implications for pathogenesis and family counseling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.01.003

The rate of recurrence of isolated congenital heart block: a population-based study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.01.003

Recurrence rates of cardiac manifestations associated with neonatal lupus and maternal/fetal risk factors.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.01.003

Development of heart block in children of SSA/SSB-autoantibody-positive women is associated with maternal age and displays a season-of-birth pattern

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.01.003

Ro52, Ro60 and La IgG autoantibody levels and Ro52 IgG subclass profiles longitudinally throughout pregnancy in congenital heart block risk pregnancies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.01.003

Maternal connective tissue disease and congenital heart block. Demonstration of immunoglobulin in cardiac tissue

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.01.003

Cardiac immunoglobulin deposition in congenital heart block associated with maternal anti-Ro autoantibodies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.01.003

The Sjogren's syndrome-associated autoantigen Ro52 is an E3 ligase that regulates proliferation and cell death

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.01.003

Loss of the lupus autoantigen Ro52/Trim21 induces tissue inflammation and systemic autoimmunity by disregulating the IL-23-Th17 pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.01.003

Gene disruption study reveals a nonredundant role for TRIM21/Ro52 in NF-kappaB-dependent cytokine expression in fibroblasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.01.003

BioGPS: an extensible and customizable portal for querying and organizing gene annotation resources

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.01.003

The Ro 60 kDa autoantigen: insights into cellular function and role in autoimmunity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.01.003

Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.01.003

Different temporal expression of immunodominant Ro60/60 kDa-SSA and La/SSB apotopes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.01.003

Immunohistologic evidence supports apoptosis, IgG deposition, and novel macrophage/fibroblast crosstalk in the pathologic cascade leading to congenital heart block

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.01.003

Anti-SSA/Ro and anti-SSB/La autoantibodies bind the surface of apoptotic fetal cardiocytes and promote secretion of TNF-alpha by macrophages

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.01.003

Transdifferentiation of cardiac fibroblasts, a fetal factor in anti-SSA/Ro-SSB/La antibody-mediated congenital heart block

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.01.003

Ro60 requires Y3 RNA for cell surface exposure and inflammation associated with cardiac manifestations of neonatal lupus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.01.003

Arrhythmogenicity of IgG and anti-52-kD SSA/Ro affinity-purified antibodies from mothers of children with congenital heart block

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.01.003

Serum and immunoglobulin G from the mother of a child with congenital heart block induce conduction abnormalities and inhibit L-type calcium channels in a rat heart model

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.01.003

Direct inhibition of expressed cardiac l- and t-type calcium channels by igg from mothers whose children have congenital heart block

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.01.003

Down-regulation of L-type calcium channel in pups born to 52 kDa SSA/Ro immunized rabbits.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.01.003

Autoantibodies from mothers of children with congenital heart block downregulate cardiac L-type Ca channels

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.01.003

Novel molecular mechanism involving alpha1D (Cav1.3) L-type calcium channel in autoimmune-associated sinus bradycardia.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.01.003

Congenital heart block maternal sera autoantibodies target an extracellular epitope on the α1G T-type calcium channel in human fetal hearts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.01.003

Signs of first-degree heart block occur in one-third of fetuses of pregnant women with anti-SSA/Ro 52-kd antibodies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.01.003

Diagnostic precision of Doppler flow echocardiography in fetuses at risk for atrioventricular block

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.01.003

A population-based investigation of the autoantibody profile in mothers of children with atrioventricular block

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.01.003

Maternal MHC regulates generation of pathogenic antibodies and fetal MHC-encoded genes determine susceptibility in congenital heart block

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.01.003

Anti-Ro52 monoclonal antibodies specific for amino acid 200-239, but not other Ro52 epitopes, induce congenital heart block in a rat model.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.01.003

Ro/SSA autoantibodies directly bind cardiomyocytes, disturb calcium homeostasis, and mediate congenital heart block

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.01.003

Electrocardiographic abnormalities in a murine model injected with IgG from mothers of children with congenital heart block

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.01.003

Functional role of L-type Cav1.3 Ca2+ channels in cardiac pacemaker activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.01.003

Disturbed atrio-ventricular conduction and normal contractile function in isolated hearts from Cav1.3-knockout mice.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.01.003

Voltage-dependent calcium channels and cardiac pacemaker activity: from ionic currents to genes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.01.003

Congenital heart block: identification of autoantibody binding site on the extracellular loop (domain I, S5-S6) of alpha(1D) L-type Ca channel

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.01.003

Rescue and worsening of congenital heart block-associated electrocardiographic abnormalities in two transgenic mice.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.01.003

Anti-Ro/SSA antibodies and cardiac arrhythmias in the adult: facts and hypotheses

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.01.003

Anti-Ro52/SSA antibody-exposed fetuses with prolonged atrioventricular time intervals show signs of decreased cardiac performance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.01.003

Maternal antibody responses to the 52-kd SSA/RO p200 peptide and the development of fetal conduction defects

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.01.003

Cytokine polymorphisms and histologic expression in autopsy studies: contribution of TNF-alpha and TGF-beta 1 to the pathogenesis of autoimmune-associated congenital heart block

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.01.003

Identification of candidate loci at 6p21 and 21q22 in a genome-wide association study of cardiac manifestations of neonatal lupus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.01.003

β2-glycoprotein I and protection from anti-SSA/Ro60-associated cardiac manifestations of neonatal lupus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.01.003

Calreticulin negatively regulates the surface expression of Cav1.3 L-type calcium channel.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.01.003

Progression to first-degree heart block in preschool children exposed in utero to maternal anti-SSA/Ro52 autoantibodies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.01.003

10.1016/J.YEXCR.2014.01.003

7 January 2021

Identifiers

DOI

1 reference

30 August 2017

1 reference