(Q38182857)

30 August 2017

title

Muscimol as an ionotropic GABA receptor agonist (English)

1 reference

30 August 2017

1 reference

ChEBI release 2020-05-28

Graham A R Johnston

1

1 reference

30 August 2017

publication date

29 January 2014

1 reference

30 August 2017

published in

Neurochemical Research

1 reference

30 August 2017

volume

39

1 reference

30 August 2017

issue

10

1 reference

30 August 2017

page(s)

1942-1947

1 reference

Poisonous principles of mushrooms of the genus Amanita. Four-carbon amines acting on the central nervous system and cell-destroying cyclic peptides are produced

30 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS11064-014-1245-Y

Physiological and behavioral studies with muscimol

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-014-1245-Y

On the nomenclature of a new compound from Amanita-Arten

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-014-1245-Y

Central actions of ibotenic acid and muscimol

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-014-1245-Y

Bicuculline, an antagonist of GABA and synaptic inhibition in the spinal cord of the cat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-014-1245-Y

GABA-Activated ligand gated ion channels: medicinal chemistry and molecular biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-014-1245-Y

Advantages of an antagonist: bicuculline and other GABA antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-014-1245-Y

Cis- and trans-4-aminocrotonic acid as GABA analogues of restricted conformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-014-1245-Y

Neurochemicals for the investigation of GABA(C) receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-014-1245-Y

Use of 3H-muscimol for GABA receptor studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-014-1245-Y

Structure-activity studies on the inhibition of GABA binding to rat brain membranes by muscimol and related compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-014-1245-Y

Muscimol uptake, release and binding in rat brain slices

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-014-1245-Y

Pharmacological characterization of agonists at delta-containing GABAA receptors: Functional selectivity for extrasynaptic receptors is dependent on the absence of gamma2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-014-1245-Y

Distinct activities of GABA agonists at synaptic- and extrasynaptic-type GABAA receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-014-1245-Y

Binding studies with muscimol; relation to synaptic γ-aminobutyrate receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-014-1245-Y

On high‐ and low‐affinity agonist sites in GABAA receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-014-1245-Y

A unified model of the GABA(A) receptor comprising agonist and benzodiazepine binding sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-014-1245-Y

Low nanomolar GABA effects at extrasynaptic α4β1/β3δ GABA(A) receptor subtypes indicate a different binding mode for GABA at these receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-014-1245-Y

Inhibition of GABA uptake in rat brain slices by nipecotic acid, various isoxazoles and related compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-014-1245-Y

Inhibition of the uptake of GABA and related amino acids in rat brain slices by the optical isomers of nipecotic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-014-1245-Y

Differential effects of nipecotic acid and 4,5,6,7-tetrahydroisoxazolo[4,5-c]pyridin-3-ol on extracellular gamma-aminobutyrate levels in rat thalamus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-014-1245-Y

The synthesis of novel GABA uptake inhibitors. 1. Elucidation of the structure-activity studies leading to the choice of (R)-1-[4,4-bis(3-methyl-2-thienyl)-3-butenyl]-3-piperidinecarboxylic acid (tiagabine) as an anticonvulsant drug candidate

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-014-1245-Y

Tiagabine, SK&F 89976-A, CI-966, and NNC-711 are selective for the cloned GABA transporter GAT-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-014-1245-Y

GABA transport inhibitors and seizure protection: the past and future

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-014-1245-Y

A new class of GABA agonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-014-1245-Y

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-014-1245-Y

Diazepam stimulates the binding of GABA and muscimol but not thip to rat brain membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-014-1245-Y

GABA(A) agonists and partial agonists: THIP (Gaboxadol) as a non-opioid analgesic and a novel type of hypnotic

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-014-1245-Y

Design and synthesis of a new series of 4-alkylated 3-isoxazolol GABAA antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-014-1245-Y

The orthosteric GABAA receptor ligand Thio-4-PIOL displays distinctly different functional properties at synaptic and extrasynaptic receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-014-1245-Y

Inhibition of Spinal Neurones by Glycine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-014-1245-Y

Partial GABAA Receptor Agonists. Synthesis and in Vitro Pharmacology of a Series of Nonannulated Analogs of 4,5,6,7-Tetrahydroisoxazolo[4,5-c]pyridin-3-ol

21 January 2018

1 reference

12 December 2020

Selective inhibitors of glial GABA uptake: synthesis, absolute stereochemistry, and pharmacology of the enantiomers of 3-hydroxy-4-amino-4,5,6,7-tetrahydro-1,2-benzisoxazole (exo-THPO) and analogues

1 reference

12 December 2020

4-Aminotetrolic Acid : New Conformational-restricted Analogue of γ-Aminobutyric Acid

1 reference

12 December 2020

Probing the orthosteric binding site of GABAA receptors with heterocyclic GABA carboxylic acid bioisosteres

1 reference

12 December 2020

Uptake and release of nipecotic acid by rat brain slices

1 reference

12 December 2020

The GABAA agonist THIP (gaboxadol) increases non-REM sleep and enhances delta activity in the rat

1 reference

12 December 2020

GABA uptake inhibitors containing mono- and diarylmethoxyalkyl N-substituents

1 reference

12 December 2020

Conformational analysis of muscimol, a GABA agonist

1 reference

12 December 2020

Muscimol and the uptake of ?-aminobutyric acid by rat brain slices

1 reference

12 December 2020

Differences in agonist/antagonist binding affinity and receptor transduction using recombinant human gamma-aminobutyric acid type A receptors

1 reference

12 December 2020

Structure and biological activity of a series of conformationally restricted analogues of GABA

1 reference

12 December 2020

The GABA synapse as a target for antiepileptic drugs: a historical overview focused on GABA transporters.

1 reference

12 December 2020

The Structure of Muscimol, a GABA Analogue of Restricted Conformation

1 reference

12 December 2020

Characterization of bicuculline/baclofen-insensitive (rho-like) gamma-aminobutyric acid receptors expressed in Xenopus oocytes. II. Pharmacology of gamma-aminobutyric acidA and gamma-aminobutyric acidB receptor agonists and antagonists

1 reference

12 December 2020

10.1007/S11064-014-1245-Y

Identifiers

DOI

1 reference

Dimensions Publication ID

30 August 2017

1050397883

0 references

1 reference