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STAT2 and IRF9: Beyond ISGF3.
scientific article published on October 2013
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
3906322
retrieved
30 August 2017
title
STAT2 and IRF9: Beyond ISGF3.
(English)
1 reference
stated in
Europe PubMed Central
PMCID
3906322
retrieved
30 August 2017
author
Nathalie Grandvaux
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
3906322
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24498542%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 June 2020
author name string
Karin Fink
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
3906322
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24498542%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 June 2020
language of work or name
English
1 reference
based on heuristic
inferred from title
publication date
1 October 2013
1 reference
stated in
Europe PubMed Central
PMCID
3906322
retrieved
30 August 2017
published in
JAK-STAT
1 reference
stated in
Europe PubMed Central
PMCID
3906322
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24498542%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 June 2020
volume
2
1 reference
stated in
Europe PubMed Central
PMCID
3906322
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24498542%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 June 2020
issue
4
1 reference
stated in
Europe PubMed Central
PMCID
3906322
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24498542%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 June 2020
page(s)
e27521
1 reference
stated in
Europe PubMed Central
PMCID
3906322
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24498542%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 June 2020
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Transcriptional regulation by STAT1 and STAT2 in the interferon JAK-STAT pathway
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6 September 2017
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IFNβ/TNFα synergism induces a non-canonical STAT2/IRF9-dependent pathway triggering a novel DUOX2 NADPH oxidase-mediated airway antiviral response.
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6 September 2017
Identification of STAT2 serine 287 as a novel regulatory phosphorylation site in type I interferon-induced cellular responses
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Mice deficient in STAT1 but not STAT2 or IRF9 develop a lethal CD4+ T-cell-mediated disease following infection with lymphocytic choriomeningitis virus.
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6 September 2017
Interferon-stimulated genes and their antiviral effector functions
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6 September 2017
Inhibitor of κB kinase epsilon (IKK(epsilon)), STAT1, and IFIT2 proteins define novel innate immune effector pathway against West Nile virus infection
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6 September 2017
STAT2 mediates innate immunity to Dengue virus in the absence of STAT1 via the type I interferon receptor
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A novel role for IFN-stimulated gene factor 3II in IFN-γ signaling and induction of antiviral activity in human cells
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6 September 2017
TNFα and IFNγ synergistically enhance transcriptional activation of CXCL10 in human airway smooth muscle cells via STAT-1, NF-κB, and the transcriptional coactivator CREB-binding protein
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6 September 2017
Organization of the mouse RNA-specific adenosine deaminase Adar1 gene 5'-region and demonstration of STAT1-independent, STAT2-dependent transcriptional activation by interferon
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6 September 2017
Type I IFN induced IL1-Ra expression in hepatocytes is mediated by activating STAT6 through the formation of STAT2: STAT6 heterodimer
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6 September 2017
Independent and Cooperative Antiviral Actions of Beta Interferon and Gamma Interferon against Herpes Simplex Virus Replication in Primary Human Fibroblasts
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6 September 2017
STAT activation and differential complex formation dictate selectivity of interferon responses
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6 September 2017
Multiple functions of the IKK-related kinase IKKepsilon in interferon-mediated antiviral immunity
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6 September 2017
Identification of GAS-dependent interferon-sensitive target genes whose transcription is STAT2-dependent but ISGF3-independent
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PubMed Central
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6 September 2017
Differential regulation of interferon regulatory factor (IRF)-7 and IRF-9 gene expression in the central nervous system during viral infection
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906322
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6 September 2017
Mechanisms of type-I- and type-II-interferon-mediated signalling
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906322
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6 September 2017
Resolution of primary severe acute respiratory syndrome-associated coronavirus infection requires Stat1.
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6 September 2017
Synergistic transcriptional activation of indoleamine dioxygenase by IFN-gamma and tumor necrosis factor-alpha
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6 September 2017
Phosphorylation of the Stat1 transactivating domain is required for the response to type I interferons
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PubMed Central
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6 September 2017
A hybrid IRF9-STAT2 protein recapitulates interferon-stimulated gene expression and antiviral response
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6 September 2017
IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex
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PubMed Central
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6 September 2017
IL-28, IL-29 and their class II cytokine receptor IL-28R
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PubMed Central
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6 September 2017
Tumor necrosis factor alpha (TNF-alpha) activates Jak1/Stat3-Stat5B signaling through TNFR-1 in human B cells
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PubMed Central
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6 September 2017
Stat1 as a component of tumor necrosis factor alpha receptor 1-TRADD signaling complex to inhibit NF-kappaB activation
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6 September 2017
IFN-alpha activates Stat6 and leads to the formation of Stat2:Stat6 complexes in B cells
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906322
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6 September 2017
Activation of the transcription factor ISGF3 by interferon-gamma
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906322
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6 September 2017
Induction of Jak/STAT signaling by activation of the type 1 TNF receptor
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906322
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6 September 2017
Synergistic activation of NF-kappaB by tumor necrosis factor alpha and gamma interferon via enhanced I kappaB alpha degradation and de novo I kappaBbeta degradation
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906322
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6 September 2017
Distinct STAT structure promotes interaction of STAT2 with the p48 subunit of the interferon-alpha-stimulated transcription factor ISGF3
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906322
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6 September 2017
Essential and non-redundant roles of p48 (ISGF3 gamma) and IRF-1 in both type I and type II interferon responses, as revealed by gene targeting studies
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906322
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6 September 2017
Stat2 is a transcriptional activator that requires sequence-specific contacts provided by stat1 and p48 for stable interaction with DNA
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906322
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6 September 2017
Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906322
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6 September 2017
Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway
1 reference
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PubMed Central
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6 September 2017
Two domains of ISGF3 gamma that mediate protein-DNA and protein-protein interactions during transcription factor assembly contribute to DNA-binding specificity
1 reference
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PubMed Central
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6 September 2017
Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
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6 September 2017
Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906322
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6 September 2017
Tyrosine-phosphorylated Stat1 and Stat2 plus a 48-kDa protein all contact DNA in forming interferon-stimulated-gene factor 3
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906322
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6 September 2017
IRF-9/STAT2 [corrected] functional interaction drives retinoic acid-induced gene G expression independently of STAT1.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906322
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14 September 2017
Critical roles for both STAT1-dependent and STAT1-independent pathways in the control of primary dengue virus infection in mice
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906322
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14 September 2017
The transcriptional coactivator CREB-binding protein cooperates with STAT1 and NF-kappa B for synergistic transcriptional activation of the CXC ligand 9/monokine induced by interferon-gamma gene.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906322
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14 September 2017
The interferon-inducible Stat2:Stat1 heterodimer preferentially binds in vitro to a consensus element found in the promoters of a subset of interferon-stimulated genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906322
retrieved
28 September 2017
Importance of the two interferon-stimulated response element (ISRE) sequences in the regulation of the human indoleamine 2,3-dioxygenase gene
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906322
retrieved
28 September 2017
A cytomegaloviral protein reveals a dual role for STAT2 in IFN-{gamma} signaling and antiviral responses
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906322
retrieved
23 June 2018
Synergy between interferon-gamma and tumor necrosis factor-alpha in transcriptional activation is mediated by cooperation between signal transducer and activator of transcription 1 and nuclear factor kappaB.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906322
retrieved
23 June 2018
Antiviral activity of tumour necrosis factor. Synergism with interferons and induction of oligo-2',5'-adenylate synthetase
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906322
retrieved
23 June 2018
The addition of tumor necrosis factor plus beta interferon induces a novel synergistic antiviral state against poxviruses in primary human fibroblasts
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906322
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31 August 2018
Viruses evade the immune system through type I interferon-mediated STAT2-dependent, but STAT1-independent, signaling
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906322
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31 August 2018
SOCS-1 suppresses TNF-alpha-induced apoptosis through the regulation of Jak activation
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906322
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31 August 2018
Tumor necrosis factor alpha modulates airway smooth muscle function via the autocrine action of interferon beta
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906322
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31 August 2018
Overexpression of IRF9 confers resistance to antimicrotubule agents in breast cancer cells.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906322
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31 August 2018
Regulation of IFN-alpha/beta genes: evidence for a dual function of the transcription factor complex ISGF3 in the production and action of IFN-alpha/beta.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906322
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31 August 2018
Possible involvement of the transcription factor ISGF3 gamma in virus-induced expression of the IFN-beta gene
1 reference
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reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906322
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31 August 2018
Cytoplasmic activation of ISGF3, the positive regulator of interferon-alpha-stimulated transcription, reconstituted in vitro
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906322
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1 October 2018
TNF activates an IRF1-dependent autocrine loop leading to sustained expression of chemokines and STAT1-dependent type I interferon–response genes
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24498542
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Immune response in Stat2 knockout mice
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24498542
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Tumor necrosis factor acts synergistically with autocrine interferon-beta and increases interferon-beta mRNA levels in human fibroblasts
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24498542
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
STAT1-independent cell type-specific regulation of antiviral APOBEC3G by IFN-alpha
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24498542
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
p48/STAT-1alpha-containing complexes play a predominant role in induction of IFN-gamma-inducible protein, 10 kDa (IP-10) by IFN-gamma alone or in synergy with TNF-alpha
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24498542
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.4161/JKST.27521
1 reference
stated in
Europe PubMed Central
PMCID
3906322
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24498542%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 June 2020
PMCID
3906322
1 reference
stated in
Europe PubMed Central
PMCID
3906322
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24498542%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 June 2020
PubMed ID
24498542
1 reference
stated in
Europe PubMed Central
PMCID
3906322
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24498542%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 June 2020
ResearchGate publication ID
260109361
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