(Q38186553)

30 August 2017

title

Disc cell therapies: critical issues (English)

1 reference

30 August 2017

Marta Tibiletti

1

1 reference

30 August 2017

Nevenka Kregar Velikonja

series ordinal

2

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30 August 2017

Jill P G Urban

series ordinal

3

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30 August 2017

Jeremy C T Fairbank

series ordinal

4

1 reference

30 August 2017

publication date

8 February 2014

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30 August 2017

published in

European Spine Journal

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30 August 2017

volume

23 Suppl 3

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30 August 2017

page(s)

S375-84

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Treatment of deep cartilage defects in the knee with autologous chondrocyte transplantation

30 August 2017

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Cells from different regions of the intervertebral disc: effect of culture system on matrix expression and cell phenotype

21 January 2018

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Diversity of intervertebral disc cells: phenotype and function

21 January 2018

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Exhaustion of nucleus pulposus progenitor cells with ageing and degeneration of the intervertebral disc

21 January 2018

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Toward an understanding of the role of notochordal cells in the adult intervertebral disc: from discord to accord

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Identification of cell proliferation zones, progenitor cells and a potential stem cell niche in the intervertebral disc region: a study in four species

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Identification of novel nucleus pulposus markers: Interspecies variations and implications for cell-based therapiesfor intervertebral disc degeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Variations in gene and protein expression in human nucleus pulposus in comparison with annulus fibrosus and cartilage cells: potential associations with aging and degeneration.

21 January 2018

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In search of nucleus pulposus-specific molecular markers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Initial characterization of the metabolism of intervertebral disc cells encapsulated in microspheres

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Nanofibrous biologic laminates replicate the form and function of the annulus fibrosus

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

An injectable hydrogel incorporating mesenchymal precursor cells and pentosan polysulphate for intervertebral disc regeneration

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Injectable laminin-functionalized hydrogel for nucleus pulposus regeneration.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Repair, regenerative and supportive therapies of the annulus fibrosus: achievements and challenges

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

On the extent and nature of nucleus-annulus integration

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Role of cytokines in intervertebral disc degeneration: pain and disc content

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Biological treatment strategies for disc degeneration: potentials and shortcomings

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Stem cell regeneration of degenerated intervertebral discs: current status (update).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Hydrogels in acellular and cellular strategies for intervertebral disc regeneration.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Tissue-engineering approach to regenerating the intervertebral disc

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

An injectable vehicle for nucleus pulposus cell-based therapy.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

The differentiation of bone marrow mesenchymal stem cells into chondrocyte-like cells on poly-L-lactic acid (PLLA) scaffolds

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Clinical experience in cell-based therapeutics: disc chondrocyte transplantation A treatment for degenerated or damaged intervertebral disc

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Intradiscal injection of hematopoietic stem cells in an attempt to rejuvenate the intervertebral discs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Intervertebral disc repair by autologous mesenchymal bone marrow cells: a pilot study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Regenerative medicine: Rebuilding the backbone

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Recent advances in biological therapies for disc degeneration: tissue engineering of the annulus fibrosus, nucleus pulposus and whole intervertebral discs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Natural history of individuals with asymptomatic disc abnormalities in magnetic resonance imaging: predictors of low back pain-related medical consultation and work incapacity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Risk factors for lumbar disc degeneration: a 5-year prospective MRI study in asymptomatic individuals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Prevalence and distribution of intervertebral disc degeneration over the entire spine in a population-based cohort: the Wakayama Spine Study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Associations between radiographic lumbar spinal stenosis and clinical symptoms in the general population: the Wakayama Spine Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

A morphological study of lumbar vertebral endplates: radiographic, visual and digital measurements

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

ISSLS Prize winner: The anatomy of failure in lumbar disc herniation: an in vivo, multimodal, prospective study of 181 subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Diagnostic criteria and treatment of discogenic pain: a systematic review of recent clinical literature

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Pathophysiology, diagnosis, and treatment of discogenic low back pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

The evaluation of neuropathic components in low back pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Clinical importance of the intervertebral disc, or back pain for biochemists

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Prospective study of disc repair with allogeneic chondrocytes presented at the 2012 Joint Spine Section Meeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Efficacy of injections with Disci/Rhus toxicodendron compositum for chronic low back pain--a randomized placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Stem cell therapy for degenerative disc disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Are animal models useful for studying human disc disorders/degeneration?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Osteogenic protein-1 injection into a degenerated disc induces the restoration of disc height and structural changes in the rabbit anular puncture model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Regenerative effects of transplanting mesenchymal stem cells embedded in atelocollagen to the degenerated intervertebral disc

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Intervertebral disc repair using adipose tissue-derived stem and regenerative cells: experiments in a canine model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Osteoarthritis year in review: outcome of rehabilitation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Rehabilitation after autologous chondrocyte implantation for isolated cartilage defects of the knee.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Human lumbar apophyseal joint damage and intervertebral disc degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

2009 ISSLS Prize Winner: Does discography cause accelerated progression of degeneration changes in the lumbar disc: a ten-year matched cohort study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Deleterious effects of discography radiocontrast solution on human annulus cell in vitro: changes in cell viability, proliferation, and apoptosis in exposed cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Degenerative anular changes induced by puncture are associated with insufficiency of disc biomechanical function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Needle puncture injury causes acute and long-term mechanical deficiency in a mouse model of intervertebral disc degeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

The effects of needle puncture injury on microscale shear strain in the intervertebral disc annulus fibrosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

The transpedicular approach for the study of intervertebral disc regeneration strategies: in vivo characterization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

What is intervertebral disc degeneration, and what causes it?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

The occurrence of anular tears and their relation to lifetime back pain history: a cadaveric study using barium sulfate discography.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

The natural history of age-related disc degeneration: the pathology and sequelae of tears.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Biomechanical evaluation of conventional anulus fibrosus closure methods required for nucleus replacement. Laboratory investigation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Matrix-assisted cell transfer for intervertebral disc cell therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Methods to monitor distribution and metabolic activity of mesenchymal stem cells following in vivo injection into nucleotomized porcine intervertebral discs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Injection of a polymerized hyaluronic acid/collagen hydrogel matrix in an in vivo porcine disc degeneration model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Biaxial mechanics and inter-lamellar shearing of stem-cell seeded electrospun angle-ply laminates for annulus fibrosus tissue engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Enhancing tissue repair in annulus fibrosus defects of the intervertebral disc: analysis of a bio-integrative annulus implant in an in-vivo ovine model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Intervertebral disk nutrition: a review of factors influencing concentrations of nutrients and metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Effect of nutrient deprivation on the viability of intervertebral disc cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Nutrition of the intervertebral disc: solute transport and metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

2004 Young Investigator Award Winner: vertebral endplate marrow contact channel occlusions and intervertebral disc degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Transport properties of the human cartilage endplate in relation to its composition and calcification

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

In Vitro Diffusion of DYE Through the End-Plates and the Annulus Fibrosus of Human Lumbar Inter-Vertebral Discs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Atherosclerosis and disc degeneration/low-back pain--a systematic review

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Disc degeneration/back pain and calcification of the abdominal aorta. A 25-year follow-up study in Framingham.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

New approaches to magnetic resonance imaging of intervertebral discs, tendons, ligaments, and menisci

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

ISSLS prize winner: A study of diffusion in human lumbar discs: a serial magnetic resonance imaging study documenting the influence of the endplate on diffusion in normal and degenerate discs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Is the transport of a gadolinium-based contrast agent decreased in a degenerated or aged disc? A post contrast MRI study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

2009 ISSLS Prize Winner: What influence does sustained mechanical load have on diffusion in the human intervertebral disc?: an in vivo study using serial postcontrast magnetic resonance imaging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Review of postcontrast MRI studies on diffusion of human lumbar discs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Do intervertebral discs degenerate before they herniate, or after?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Human intervertebral disc aggrecan inhibits endothelial cell adhesion and cell migration in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Increased nerve and blood vessel ingrowth associated with proteoglycan depletion in an ovine anular lesion model of experimental disc degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Oxygen and lactate concentrations measured in vivo in the intervertebral discs of patients with scoliosis and back pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Assessment of cell viability in three-dimensional scaffolds using cellular auto-fluorescence.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Pharmacological enhancement of disc diffusion and differentiation of healthy, ageing and degenerated discs : Results from in-vivo serial post-contrast MRI studies in 365 human lumbar discs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

The role of interleukin-1 in the pathogenesis of human intervertebral disc degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Inflammatory mediators as potential therapeutic targets in the spine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Interleukin-1 receptor antagonist delivered directly and by gene therapy inhibits matrix degradation in the intact degenerate human intervertebral disc: an in situ zymographic and gene therapy study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Gene therapy for intervertebral disk degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Cell viability in scoliotic discs in relation to disc deformity and nutrient levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Investigation of solute concentrations in a 3D model of intervertebral disc

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Effect of endplate calcification and mechanical deformation on the distribution of glucose in intervertebral disc: a 3D finite element study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

The effect of extracellular pH on matrix turnover by cells of the bovine nucleus pulposus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

MSC response to pH levels found in degenerating intervertebral discs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Interactions of environmental conditions and mechanical loads have influence on matrix turnover by nucleus pulposus cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Intradiscal measurements of pH in patients with lumbar rhizopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Influence of extracellular osmolarity and mechanical stimulation on gene expression of intervertebral disc cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

An amperometric glucose-oxidase/poly(o-phenylenediamine) biosensor for monitoring brain extracellular glucose: in vivo characterisation in the striatum of freely-moving rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Overenthusiastic Interpretations of a Nonetheless Promising Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Matrix Metalloproteinases And Aggrecanase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Studies on Structural Changes in the Lumbar Annulus Fibrosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

Association of lumbar artery narrowing, degenerative changes in disc and endplate and apparent diffusion in disc on postcontrast enhancement of lumbar intervertebral disc

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00586-014-3177-2

A needle micro-osmometer for determination of glycosaminoglycan concentration in excised nucleus pulposus tissue.

21 January 2018

1 reference

12 December 2020

Abnormal magnetic-resonance scans of the lumbar spine in asymptomatic subjects. A prospective investigation

1 reference

12 December 2020

Investigation of different cell types and gel carriers for cell-based intervertebral disc therapy, in vitro and in vivo studies

1 reference

12 December 2020

Stimulation of mature canine intervertebral disc by growth factors

1 reference

12 December 2020

Characterization of the annulus fibrosus-vertebral body interface: identification of new structural features

1 reference

12 December 2020

Gene therapy for the treatment of degenerative disk disease

1 reference

12 December 2020

Biochemical changes associated with the symptomatic human intervertebral disk

1 reference

12 December 2020

Innervation of pathologies in the lumbar vertebral end plate and intervertebral disc.

1 reference

12 December 2020

Evidence of augmented central pain processing in idiopathic chronic low back pain

1 reference

12 December 2020

Comparison of animals used in disc research to human lumbar disc geometry

1 reference

12 December 2020

Enhancing annulus fibrosus tissue formation in porous silk scaffolds

1 reference

12 December 2020

Biochemical changes in intervertebral disc degeneration

1 reference

12 December 2020

Disc degeneration in low back pain: a 17-year follow-up study using magnetic resonance imaging

1 reference

12 December 2020

A novel thiol-modified hyaluronan and elastin-like polypetide composite material for tissue engineering of the nucleus pulposus of the intervertebral disc

1 reference

12 December 2020

Challenges and strategies in the repair of ruptured annulus fibrosus

1 reference

12 December 2020

Needle puncture injury affects intervertebral disc mechanics and biology in an organ culture model

1 reference

12 December 2020

Proinflammatory cytokine expression profile in degenerated and herniated human intervertebral disc tissues

1 reference

12 December 2020

The stages of disc degeneration as revealed by discograms

1 reference

12 December 2020

Factors involved in the nutrition of the human lumbar intervertebral disc: cellularity and diffusion of glucose in vitro

1 reference

12 December 2020

Cytotoxicity of local anesthetics and nonionic contrast agents on bovine intervertebral disc cells cultured in a three-dimensional culture system

1 reference

12 December 2020

The interrelationship of cell density and cartilage thickness in mammalian articular cartilage

1 reference

12 December 2020

Identification of heterogeneous cell populations in normal human intervertebral disc

1 reference

12 December 2020

Immunoselected STRO-3+ mesenchymal precursor cells and restoration of the extracellular matrix of degenerate intervertebral discs

1 reference

12 December 2020

Differential regulation of matrix degrading enzymes in a TNFalpha-induced model of nucleus pulposus tissue degeneration

1 reference

12 December 2020

Does a needle puncture into the annulus fibrosus cause disc degeneration?

1 reference

12 December 2020

Indentation stiffness of repair tissue after autologous chondrocyte transplantation.

1 reference

12 December 2020

Measuring diffusion of solutes into intervertebral disks with MR imaging and paramagnetic contrast medium

1 reference

12 December 2020

Clinical rehabilitation guidelines for matrix-induced autologous chondrocyte implantation on the tibiofemoral joint

1 reference

12 December 2020

Moderate versus mediocre: the reliability of spine MR data interpretations

1 reference

12 December 2020

Cell sources for nucleus pulposus regeneration.

1 reference

12 December 2020

Mesenchymal stem cells injection in degenerated intervertebral disc: cell leakage may induce osteophyte formation

1 reference

12 December 2020

Calcification in human intervertebral disc degeneration and scoliosis

1 reference

12 December 2020

The effect of lactate and pH on proteoglycan and protein synthesis rates in the intervertebral disc

1 reference

12 December 2020

Swelling pressure of the inervertebral disc: influence of proteoglycan and collagen contents

1 reference

12 December 2020

Prevalence and pattern of lumbar magnetic resonance imaging changes in a population study of one thousand forty-three individuals

1 reference

12 December 2020

Biochemical composition and turnover of the extracellular matrix of the normal and degenerate intervertebral disc

1 reference

12 December 2020

In vivo biofunctional evaluation of hydrogels for disc regeneration

1 reference

12 December 2020

Cell transplantation in lumbar spine disc degeneration disease

1 reference

12 December 2020

Disc regeneration therapy using marrow mesenchymal cell transplantation: a report of two case studies

1 reference

12 December 2020

Enhancing human nucleus pulposus cells for biological treatment approaches of degenerative intervertebral disc diseases: a systematic review

1 reference

12 December 2020

Tissue engineering and the intervertebral disc: the challenges

1 reference

12 December 2020

A biological approach to treating disc degeneration: not for today, but maybe for tomorrow

1 reference

12 December 2020

Proteoglycan synthesis in the intervertebral disk nucleus: the role of extracellular osmolality

1 reference

12 December 2020

Modic changes: prevalence, distribution patterns, and association with age in white men.

1 reference

12 December 2020

10.1007/S00586-014-3177-2

Identifiers

DOI

1 reference

30 August 2017

1 reference