(Q38193087)

English

The lack of a big picture in tuberculosis: the clinical point of view, the problems of experimental modeling and immunomodulation. The factors we should consider when designing novel treatment strategies

scientific article published on 14 February 2014

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scholarly article

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Europe PubMed Central

PMC publication ID

30 August 2017

1 reference

Europe PubMed Central

The lack of a big picture in tuberculosis: the clinical point of view, the problems of experimental modeling and immunomodulation. The factors we should consider when designing novel treatment strategies (English)

1 reference

Europe PubMed Central

PMC publication ID

30 August 2017

0 references

Pere-Joan Cardona i Iglesias

2

1 reference

Europe PubMed Central

PMC publication ID

30 August 2017

Cristina Vilaplana

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Cristina Vilaplana

1

0 references

publication date

14 February 2014

1 reference

Europe PubMed Central

PMC publication ID

30 August 2017

Frontiers in Microbiology

1 reference

Europe PubMed Central

PMC publication ID

30 August 2017

5

1 reference

Europe PubMed Central

PMC publication ID

30 August 2017

55

1 reference

Europe PubMed Central

PMC publication ID

30 August 2017

Management of HIV-associated tuberculosis in resource-limited settings: a state-of-the-art review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3924323

6 September 2017

Capacity of lung stroma to educate dendritic cells inhibiting mycobacteria-specific T-cell response depends upon genetic susceptibility to tuberculosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3924323

6 September 2017

Randomized clinical trial of thrice-weekly 4-month moxifloxacin or gatifloxacin containing regimens in the treatment of new sputum positive pulmonary tuberculosis patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3924323

6 September 2017

Active case finding for tuberculosis among high-risk groups in low-incidence countries

1 reference

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IL-17 and IFN-γ production in peripheral blood following BCG vaccination and Mycobacterium tuberculosis infection in human

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3924323

6 September 2017

Adjunct immunotherapies for tuberculosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3924323

6 September 2017

Low dose aerosol fitness at the innate phase of murine infection better predicts virulence amongst clinical strains of Mycobacterium tuberculosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3924323

6 September 2017

Whole-genome sequencing of rifampicin-resistant Mycobacterium tuberculosis strains identifies compensatory mutations in RNA polymerase genes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3924323

6 September 2017

Neutrophils in tuberculosis: friend or foe?

1 reference

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6 September 2017

Experimental model of tuberculosis in the domestic goat after endobronchial infection with Mycobacterium caprae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3924323

6 September 2017

A spotlight on liquefaction: evidence from clinical settings and experimental models in tuberculosis

1 reference

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6 September 2017

The secret trumps, impelling the pathogenicity of tubercle bacilli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3924323

6 September 2017

An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3924323

6 September 2017

Field evaluation of the efficacy of Mycobacterium bovis bacillus Calmette-Guerin against bovine tuberculosis in neonatal calves in Ethiopia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3924323

6 September 2017

Mycobacterium tuberculosis persistence mutants identified by screening in isoniazid-treated mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3924323

6 September 2017

Granuloma encapsulation is a key factor for containing tuberculosis infection in minipigs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3924323

6 September 2017

Revisiting the natural history of tuberculosis. The inclusion of constant reinfection, host tolerance, and damage-response frameworks leads to a better understanding of latent infection and its evolution towards active disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3924323

6 September 2017

The spread of tubercle bacilli by sputum, blood and lymph in pulmonary tuberculosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3924323

6 September 2017

The spectrum of latent tuberculosis: rethinking the biology and intervention strategies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3924323

6 September 2017

Determinants of regional ventilation and blood flow in the lung

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3924323

6 September 2017

MVA.85A boosting of BCG and an attenuated, phoP deficient M. tuberculosis vaccine both show protective efficacy against tuberculosis in rhesus macaques

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3924323

6 September 2017

A dynamic reinfection hypothesis of latent tuberculosis infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3924323

6 September 2017

Cell-mediated immune responses in tuberculosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3924323

6 September 2017

Innate immunity in tuberculosis: myths and truth.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3924323

6 September 2017

Comparative pathogenesis of Mycobacterium marinum and Mycobacterium tuberculosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3924323

6 September 2017

Macrophage and T cell dynamics during the development and disintegration of mycobacterial granulomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3924323

6 September 2017

Long term efficacy of DOTS regimens for tuberculosis: systematic review.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3924323

6 September 2017

Neutrophil-mediated innate immune resistance to mycobacteria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3924323

6 September 2017

Isoniazid preventive therapy and risk for resistant tuberculosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3924323

6 September 2017

RUTI: a new chance to shorten the treatment of latent tuberculosis infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3924323

6 September 2017

The success and failure of BCG - implications for a novel tuberculosis vaccine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3924323

6 September 2017

Properties and protective value of the secondary versus primary T helper type 1 response to airborne Mycobacterium tuberculosis infection in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3924323

6 September 2017

Cattle as a model for development of vaccines against human tuberculosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3924323

6 September 2017

Moxifloxacin-containing regimens of reduced duration produce a stable cure in murine tuberculosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3924323

6 September 2017

Quantitative relationships for specific growth rates and macromolecular compositions of Mycobacterium tuberculosis, Streptomyces coelicolor A3(2) and Escherichia coli B/r: an integrative theoretical approach

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3924323

6 September 2017

M. tuberculosis persistence, latency, and drug tolerance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3924323

6 September 2017

ExperimentalMycobacterium tuberculosisInfection of Cynomolgus Macaques Closely Resembles the Various Manifestations of HumanM. tuberculosisInfection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3924323

6 September 2017

Structure, function, and biogenesis of the cell wall of Mycobacterium tuberculosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3924323

6 September 2017

Mycobacterium tuberculosis in the Extracellular Compartment: an Underestimated Adversary

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3924323

6 September 2017

Divergent effect of bacillus Calmette-Guérin (BCG) vaccination on Mycobacterium tuberculosis infection in highly related macaque species: implications for primate models in tuberculosis vaccine research

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3924323

6 September 2017

Immunology of tuberculosis

1 reference

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6 September 2017

How much isoniazid is needed for prevention of tuberculosis among immunocompetent adults?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3924323

6 September 2017

Cavitary tuberculosis produced in rabbits by aerosolized virulent tubercle bacilli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3924323

6 September 2017

Impaired fitness of Mycobacterium tuberculosis resistant isolates in a cell culture model of murine macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3924323

6 September 2017

Effectiveness and safety of a treatment regimen based on isoniazid plus vaccination with Mycobacterium tuberculosis cells' fragments: field-study with naturally Mycobacterium caprae-infected goats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3924323

14 September 2017

Mycobacterium tuberculosis effects on fibroblast collagen metabolism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3924323

14 September 2017

Dormancy of Mycobacterium tuberculosis and latency of disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3924323

14 September 2017

Bacteriologic basis of short-course chemotherapy for tuberculosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3924323

14 September 2017

Pathogenesis of experimental tuberculosis in animal models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3924323

28 September 2017

Mode of action of antituberculous drugs and mechanisms of drug resistance in Mycobacterium tuberculosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3924323

28 September 2017

Treatment of monocytes with interleukin (IL)-12 plus IL-18 stimulates survival, differentiation and the production of CXC chemokine ligands (CXCL)8, CXCL9 and CXCL10.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3924323

23 June 2018

Damaging role of neutrophilic infiltration in a mouse model of progressive tuberculosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3924323

31 August 2018

Ibuprofen therapy resulted in significantly decreased tissue bacillary loads and increased survival in a new murine experimental model of active tuberculosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3924323

31 August 2018

The recombinant tuberculosis vaccine rBCG ΔureC::hly(+) induces apoptotic vesicles for improved priming of CD4(+) and CD8(+) T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3924323

31 August 2018

Neutrophils recruited to the site of Mycobacterium bovis BCG infection undergo apoptosis and modulate lipid body biogenesis and prostaglandin E production by macrophages.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3924323

31 August 2018

Delay of phagosome maturation by a mycobacterial lipid is reversed by nitric oxide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3924323

31 August 2018

[The anatomical-clinical conceptualisation of pulmonary tuberculosis in the work of Laennec].

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3924323

31 August 2018

Macrophages acquire neutrophil granules for antimicrobial activity against intracellular pathogens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3924323

31 August 2018

Catalase-peroxidase activity has no influence on virulence in a murine model of tuberculosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3924323

31 August 2018

Nonsteroidal Antiinflammatory Drugs for Adjunctive Tuberculosis Treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3924323

1 October 2018

Experimental short-course preventive therapy of tuberculosis with rifampin and pyrazinamide

1 reference

https://pubmed.ncbi.nlm.nih.gov/24592258

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidemiology of tuberculosis in the United States

1 reference

https://pubmed.ncbi.nlm.nih.gov/24592258

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blood-gas transfer of O2 and CO2 in the lungs: new models, measurements and conclusions

1 reference

https://pubmed.ncbi.nlm.nih.gov/24592258

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Persistence of DNA from Mycobacterium tuberculosis in superficially normal lung tissue during latent infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/24592258

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cavitation in pulmonary tuberculosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/24592258

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intragranulomatous necrosis in lungs of mice infected by aerosol with Mycobacterium tuberculosis is related to bacterial load rather than to any one cytokine or T cell type

1 reference

https://pubmed.ncbi.nlm.nih.gov/24592258

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

On the nature of genetic resistance to tuberculosis in the light of the host-parasite relationships in natively resistant and susceptible rabbits

1 reference

https://pubmed.ncbi.nlm.nih.gov/24592258

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Intravenous Model of Murine Tuberculosis is Less Pathogenic Than the Aerogenic Model Owing to a More Rapid Induction of Systemic Immunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/24592258

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic architecture of tuberculosis resistance in a mouse model of infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/24592258

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mouse and guinea pig models for testing new tuberculosis vaccines

1 reference

https://pubmed.ncbi.nlm.nih.gov/24592258

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Passive serum therapy with polyclonal antibodies against Mycobacterium tuberculosis protects against post-chemotherapy relapse of tuberculosis infection in SCID mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/24592258

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3389/FMICB.2014.00055

1 reference

Europe PubMed Central

PMC publication ID

30 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

30 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

30 August 2017

ResearchGate publication ID

0 references

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