(Q38195783)

30 August 2017

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title

FTO and obesity: mechanisms of association (English)

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30 August 2017

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Xu Zhao

1

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30 August 2017

Ying Yang

2

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30 August 2017

Bao-Fa Sun

3

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30 August 2017

Yong-Liang Zhao

4

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30 August 2017

Yun-Gui Yang

5

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30 August 2017

publication date

1 January 2014

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30 August 2017

published in

Current diabetes report

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30 August 2017

volume

14

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30 August 2017

issue

5

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30 August 2017

page(s)

486

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https://scigraph.springernature.com/pub.10.1007/s11892-014-0486-0

30 August 2017

exact match

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cites work

Genetics and epigenetics of obesity

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https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

The human obesity gene map: the 2005 update

21 January 2018

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FTO: the first gene contributing to common forms of human obesity

21 January 2018

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Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

Genome wide association (GWA) study for early onset extreme obesity supports the role of fat mass and obesity associated gene (FTO) variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

Variation in FTO contributes to childhood obesity and severe adult obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

FTO genotype is associated with phenotypic variability of body mass index

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

Impact of FTO genotypes on BMI and weight in polycystic ovary syndrome: a systematic review and meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

Polymorphisms of the FTO gene are associated with variation in energy intake, but not energy expenditure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

The FTO gene and measured food intake in children

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

An obesity-associated FTO gene variant and increased energy intake in children

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

The rs9939609 gene variant in FTO modified the metabolic response of weight loss after a 3-month intervention with a hypocaloric diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

Variation in the FTO gene influences food intake but not energy expenditure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

Variants in the fat mass- and obesity-associated (FTO) gene are not associated with obesity in a Chinese Han population

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

Common variation in the fat mass and obesity-associated (FTO) gene confers risk of obesity and modulates BMI in the Chinese population

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

Obesity susceptibility genetic variants identified from recent genome-wide association studies: implications in a chinese population

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

Regulation of FTO and FTM expression during human preadipocyte differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

The common rs9939609 gene variant of the fat mass- and obesity-associated gene FTO is related to fat cell lipolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

Gene expression of FTO in human subcutaneous adipose tissue, peripheral blood mononuclear cells and adipocyte cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

Regulation and function of FTO mRNA expression in human skeletal muscle and subcutaneous adipose tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

Inverse relationship between obesity and FTO gene expression in visceral adipose tissue in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

Association between the FTO rs9939609 polymorphism and leptin in European adolescents: a possible link with energy balance control. The HELENA study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

Subcutaneous and visceral adipose tissue FTO gene expression and adiposity, insulin action, glucose metabolism, and inflammatory adipokines in type 2 diabetes mellitus and in health.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

Common variant rs9939609 in gene FTO confers risk to polycystic ovary syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

The role of the fat mass and obesity associated gene (FTO) in breast cancer risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

The obesity-associated polymorphisms FTO rs9939609 and MC4R rs17782313 and endometrial cancer risk in non-Hispanic white women

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

Association of obesity-related genetic variants with endometrial cancer risk: a report from the Shanghai Endometrial Cancer Genetics Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

Body mass index and obesity- and diabetes-associated genotypes and risk for pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

Association study of type 2 diabetes genetic susceptibility variants and risk of pancreatic cancer: an analysis of PanScan-I data

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

Diabetes genes and prostate cancer in the Atherosclerosis Risk in Communities study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

Associations between an obesity related genetic variant (FTO rs9939609) and prostate cancer risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

FTO polymorphisms are associated with adult body mass index (BMI) and colorectal adenomas in African-Americans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

Obesity and cancer: Mendelian randomization approach utilizing the FTO genotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

Association between FTO gene polymorphism and cancer risk: evidence from 16,277 cases and 31,153 controls.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

A commonly carried allele of the obesity-related FTO gene is associated with reduced brain volume in the healthy elderly

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

Inactivation of the Fto gene protects from obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

FTO deficiency induces UCP-1 expression and mitochondrial uncoupling in adipocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

The fat mass and obesity associated gene FTO functions in the brain to regulate postnatal growth in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

A mouse model for the metabolic effects of the human fat mass and obesity associated FTO gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

Overexpression of Fto leads to increased food intake and results in obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

Adult onset global loss of the fto gene alters body composition and metabolism in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

The fat mass and obesity associated gene (Fto) regulates activity of the dopaminergic midbrain circuitry

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

Dopamine D2 receptors in addiction-like reward dysfunction and compulsive eating in obese rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

Brain dopamine and obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

The obesity-associated Fto gene is a transcriptional coactivator

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

Type 2 diabetes susceptibility gene expression in normal or diabetic sorted human alpha and beta cells: correlations with age or BMI of islet donors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

Relationship between blood glucose levels and hepatic Fto mRNA expression in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

FTO levels affect RNA modification and the transcriptome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

Hypothalamic-specific manipulation of Fto, the ortholog of the human obesity gene FTO, affects food intake in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

FTO is expressed in neurones throughout the brain and its expression is unaltered by fasting

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

FTO expression is regulated by availability of essential amino acids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

Role for the obesity-related FTO gene in the cellular sensing of amino acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

Functional coupling analysis suggests link between the obesity gene FTO and the BDNF-NTRK2 signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

Fasting induced cytoplasmic Fto expression in some neurons of rat hypothalamus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

Oxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTO

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

Crystal structure of the FTO protein reveals basis for its substrate specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

Comprehensive analysis of mRNA methylation reveals enrichment in 3' UTRs and near stop codons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

The birth of the Epitranscriptome: deciphering the function of RNA modifications

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

N6-methyl-adenosine modification in messenger and long non-coding RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

N6-methyl-adenosine (m6A) in RNA: an old modification with a novel epigenetic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

Reversible RNA adenosine methylation in biological regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

Nucleic acid modifications with epigenetic significance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

FTO-mediated formation of N6-hydroxymethyladenosine and N6-formyladenosine in mammalian RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

Methylated nucleotides block 5' terminus of HeLa cell messenger RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

The methylated constituents of L cell messenger RNA: evidence for an unusual cluster at the 5' terminus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

Characterization of Novikoff hepatoma mRNA methylation and heterogeneity in the methylated 5' terminus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

The biology of FTO: from nucleic acid demethylase to amino acid sensor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

A METTL3-METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

Epigenetics in human disease and prospects for epigenetic therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

Epigenetic modifications and human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

Analysis of RNA base modification and structural rearrangement by single-molecule real-time detection of reverse transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

Enhanced 5-methylcytosine detection in single-molecule, real-time sequencing via Tet1 oxidation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

Sensitive and specific single-molecule sequencing of 5-hydroxymethylcytosine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

Development of cell-active N6-methyladenosine RNA demethylase FTO inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-014-0486-0

21 January 2018

1 reference

12 December 2020

Purification and cDNA cloning of the AdoMet-binding subunit of the human mRNA (N6-adenosine)-methyltransferase

1 reference

12 December 2020

FTO effect on energy demand versus food intake

1 reference

12 December 2020

Involvement of leptin receptor long isoform (LepRb)-STAT3 signaling pathway in brain fat mass- and obesity-associated (FTO) downregulation during energy restriction

1 reference

12 December 2020

The fat mass- and obesity-associated locus and dietary intake in children

1 reference

12 December 2020

The obesity gene and colorectal cancer risk: a population study in Northern Italy

1 reference

12 December 2020

T-HOD: a literature-based candidate gene database for hypertension, obesity and diabetes

1 reference

12 December 2020

Sprouts of RNA epigenetics: the discovery of mammalian RNA demethylases.

1 reference

12 December 2020

The WHO report "Preventing chronic diseases: a vital investment" and us

1 reference

12 December 2020

A variant in FTO shows association with melanoma risk not due to BMI

1 reference

12 December 2020

10.1007/S11892-014-0486-0

Identifiers

DOI

1 reference

Dimensions Publication ID

30 August 2017

1037436963

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Fatcat ID

release_ktrhdmttlnazncxstakvvizuu4

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Fatcat

https://api.fatcat.wiki/v0/release/ktrhdmttlnazncxstakvvizuu4

24 November 2022

mapped directly with Wikidata item

1 reference