(Q36617006)

15 August 2017

Role for the obesity-related FTO gene in the cellular sensing of amino acids (English)

1 reference

15 August 2017

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9

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15 August 2017

Heather P Harding

5

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Roger Cox

Roger D Cox

12

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Stephen O'Rahilly

Stephen O'Rahilly

14

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Anthony P Coll

Anthony P Coll

13

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Paul J Lehner

Paul J Lehner

10

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Giles See How Yeo

15

Giles S H Yeo

1 reference

15 August 2017

Pawan Gulati

1

1 reference

15 August 2017

Man Ka Cheung

2

1 reference

15 August 2017

Robin Antrobus

3

1 reference

15 August 2017

Chris D Church

4

1 reference

15 August 2017

Yi-Chun Loraine Tung

6

1 reference

15 August 2017

Debra Rimmington

7

1 reference

15 August 2017

Marcella Ma

8

1 reference

15 August 2017

Frances M Ashcroft

11

1 reference

15 August 2017

language of work or name

English

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publication date

28 January 2013

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Proceedings of the National Academy of Sciences of the United States of America

15 August 2017

1 reference

15 August 2017

110

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15 August 2017

7

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15 August 2017

2557-2562

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FTO expression is regulated by availability of essential amino acids.

15 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3574930

Comprehensive analysis of mRNA methylation reveals enrichment in 3' UTRs and near stop codons

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3574930

Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3574930

Leucyl-tRNA synthetase is an intracellular leucine sensor for the mTORC1-signaling pathway

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3574930

Leucyl-tRNA synthetase controls TORC1 via the EGO complex

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3574930

N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3574930

Overexpression of Fto leads to increased food intake and results in obesity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3574930

The genetics of obesity: FTO leads the way.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3574930

Hypothalamic-specific manipulation of Fto, the ortholog of the human obesity gene FTO, affects food intake in rats.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3574930

Loss-of-function mutation in the dioxygenase-encoding FTO gene causes severe growth retardation and multiple malformations

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3574930

Molecular mechanisms of mTOR-mediated translational control

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3574930

Inactivation of the Fto gene protects from obesity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3574930

An obesity-associated FTO gene variant and increased energy intake in children

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3574930

Variation in the FTO gene influences food intake but not energy expenditure

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3574930

The FTO gene and measured food intake in children

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3574930

Oxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTO

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3574930

Obesity associated genetic variation in FTO is associated with diminished satiety

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3574930

Polymorphisms of the FTO gene are associated with variation in energy intake, but not energy expenditure

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3574930

The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3574930

A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3574930

Hypothalamic mTOR signaling regulates food intake

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3574930

Functional expansion of aminoacyl-tRNA synthetases and their interacting factors: new perspectives on housekeepers

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3574930

Active aminoacyl-tRNA synthetases are present in nuclei as a high molecular weight multienzyme complex

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3574930

Nucleolar localization of human methionyl-tRNA synthetase and its role in ribosomal RNA synthesis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3574930

Macromolecular assemblage of aminoacyl-tRNA synthetases: identification of protein-protein interactions and characterization of a core protein

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3574930

Compartmentalization of certain components of the protein synthesis apparatus in mammalian cells.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3574930

In search of an "autophagomometer".

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3574930

Obesity, FTO gene variant, and energy intake in children.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3574930

SUnSET, a nonradioactive method to monitor protein synthesis.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3574930

20 September 2018

Identifiers

DOI

10.1073/PNAS.1222796110

1 reference

15 August 2017

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1 reference

15 August 2017

1 reference