(Q24307790)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22424946%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

title

Leucyl-tRNA synthetase is an intracellular leucine sensor for the mTORC1-signaling pathway (English)

1 reference

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Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1

26 January 2020

main subject

1 reference

Regulatory associated protein of MTOR complex 1

1 reference

Isoleucyl-tRNA synthetase 1

1 reference

mechanistic target of rapamycin kinase

1 reference

Ras related GTP binding C

1 reference

Ras related GTP binding B

1 reference

Ras related GTP binding D

1 reference

Leucyl-tRNA synthetase 1

1 reference

Methionyl-tRNA synthetase 1

1 reference

cellular response to leucine starvation

1 reference

author

Sung Ho Ryu

8

1 reference

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26 January 2020

author name string

Jung Min Han

1

1 reference

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26 January 2020

Seung Jae Jeong

2

1 reference

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26 January 2020

Min Chul Park

3

1 reference

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26 January 2020

Gyuyoup Kim

4

1 reference

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26 January 2020

Nam Hoon Kwon

5

1 reference

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26 January 2020

Hoi Kyoung Kim

6

1 reference

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26 January 2020

Sang Hoon Ha

7

1 reference

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26 January 2020

Sunghoon Kim

9

1 reference

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26 January 2020

language of work or name

English

0 references

publication date

15 March 2012

1 reference

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26 January 2020

1 reference

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26 January 2020

volume

149

1 reference

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26 January 2020

page(s)

410-424

1 reference

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26 January 2020

issue

2

1 reference

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Regulation of amino acid-sensitive TOR signaling by leucine analogues in adipocytes

26 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.02.044

7 January 2021

mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.02.044

7 January 2021

Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids

1 reference

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7 January 2021

The two TORCs and Akt.

1 reference

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7 January 2021

Autophagy in cellular growth control

1 reference

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7 January 2021

The Vam6 GEF controls TORC1 by activating the EGO complex

1 reference

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7 January 2021

Functional expansion of aminoacyl-tRNA synthetases and their interacting factors: new perspectives on housekeepers

1 reference

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7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.02.044

7 January 2021

Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.02.044

7 January 2021

Structural and functional considerations of the aminoacylation reaction

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.02.044

7 January 2021

The 'KMSKS' motif in tyrosyl-tRNA synthetase participates in the initial binding of tRNA(Tyr)

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.02.044

7 January 2021

Partition of tRNA synthetases into two classes based on mutually exclusive sets of sequence motifs

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.02.044

7 January 2021

Regulation of TORC1 by Rag GTPases in nutrient response

1 reference

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7 January 2021

Molecular mechanisms of mTOR-mediated translational control

1 reference

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7 January 2021

Orthogonal use of a human tRNA synthetase active site to achieve multifunctionality

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.02.044

7 January 2021

The crystal structure of leucyl-tRNA synthetase complexed with tRNALeu in the post-transfer-editing conformation

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.02.044

7 January 2021

Regulation of the small GTPase Rheb by amino acids.

1 reference

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7 January 2021

Aminoacyl tRNA synthetases and their connections to disease

1 reference

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7 January 2021

Cloning of a novel family of mammalian GTP-binding proteins (RagA, RagBs, RagB1) with remote similarity to the Ras-related GTPases

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.02.044

7 January 2021

VE-cadherin links tRNA synthetase cytokine to anti-angiogenic function.

1 reference

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7 January 2021

Novel G proteins, Rag C and Rag D, interact with GTP-binding proteins, Rag A and Rag B

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.02.044

7 January 2021

Glutamine-dependent antiapoptotic interaction of human glutaminyl-tRNA synthetase with apoptosis signal-regulating kinase 1

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.02.044

7 January 2021

The C-terminal appended domain of human cytosolic leucyl-tRNA synthetase is indispensable in its interaction with arginyl-tRNA synthetase in the multi-tRNA synthetase complex

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.02.044

7 January 2021

The tuberous sclerosis protein TSC2 is not required for the regulation of the mammalian target of rapamycin by amino acids and certain cellular stresses

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.02.044

7 January 2021

Re-evaluating the roles of proposed modulators of mammalian target of rapamycin complex 1 (mTORC1) signaling

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.02.044

7 January 2021

Mammalian target of rapamycin (mTOR): conducting the cellular signaling symphony

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.02.044

7 January 2021

Nucleolar localization of human methionyl-tRNA synthetase and its role in ribosomal RNA synthesis

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.02.044

7 January 2021

Rab7: a key to lysosome biogenesis

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.02.044

7 January 2021

The 2 Å crystal structure of leucyl-tRNA synthetase and its complex with a leucyl-adenylate analogue

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.02.044

7 January 2021

Oral leucine administration stimulates protein synthesis in rat skeletal muscle

1 reference

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7 January 2021

Sequence, structural and evolutionary relationships between class 2 aminoacyl-tRNA synthetases

1 reference

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7 January 2021

Modular pathways for editing non-cognate amino acids by human cytoplasmic leucyl-tRNA synthetase

1 reference

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7 January 2021

Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E

1 reference

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7 January 2021

Reactions sequence of leucine activation catalysed by leucyl-RNA synthetase. 2. Formation of complexes between the enzyme and substrates.

1 reference

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7 January 2021

Regulation of polypeptide chain initiation and activity of initiation factor eIF-2 in Chinese-hamster-ovary cell mutants containing temperature-sensitive aminoacyl-tRNA synthetases

1 reference

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7 January 2021

Leucine and protein synthesis: mTOR and beyond

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.02.044

7 January 2021

The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.02.044

7 January 2021

Function and regulation of ras.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.02.044

7 January 2021

Regulation mechanisms and signaling pathways of autophagy

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.02.044

7 January 2021

Aminoacyl-tRNA synthetase complexes: beyond translation

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.02.044

7 January 2021

10.1016/J.CELL.2012.02.044

Identifiers

DOI

2 references

Consolidated OpenCitations Corpus – April 2017

789570

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22424946%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

789570

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

2 references

789570

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22424946%20AND%20SRC:MED&resulttype=core&format=json