(Q38205041)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24738947%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

title

Understanding the biology of reactive oxygen species and their link to cancer: NADPH oxidases as novel pharmacological targets (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24738947%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

1 reference

reactive oxygen species

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24738947%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

author name string

Ian P Harrison

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24738947%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

publication date

1 August 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24738947%20AND%20SRC:MED&resulttype=core&format=json

Clinical and Experimental Pharmacology and Physiology

14 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24738947%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

volume

41

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24738947%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

issue

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24738947%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

page(s)

533-542

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24738947%20AND%20SRC:MED&resulttype=core&format=json

Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008

14 March 2020

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Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo

21 January 2018

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Inhibition of tumor angiogenesis and growth by a small-molecule multi-FGF receptor blocker with allosteric properties

21 January 2018

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Mechanisms contributing to cerebral infarct size after stroke: gender, reperfusion, T lymphocytes, and Nox2-derived superoxide

21 January 2018

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Direct evidence of a role for Nox2 in superoxide production, reduced nitric oxide bioavailability, and early atherosclerotic plaque formation in ApoE-/- mice

21 January 2018

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https://api.crossref.org/works/10.1111%2F1440-1681.12238

Glutathione peroxidase-1 reduces influenza A virus-induced lung inflammation.

21 January 2018

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Inhibition of Nox2 oxidase activity ameliorates influenza A virus-induced lung inflammation

21 January 2018

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Suppressing production of reactive oxygen species (ROS) for influenza A virus therapy.

21 January 2018

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Mechanisms of angiogenesis

21 January 2018

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Synergistic angiogenic effect of codelivering fibroblast growth factor 2 and granulocyte-colony stimulating factor from fibrin scaffolds and bone marrow transplantation in critical limb ischemia

21 January 2018

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Deterministic and stochastic aspects of VEGF-A production and the cooperative behavior of tumoral cell colony.

21 January 2018

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21 January 2018

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21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Angiogenesis in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Directed in vivo angiogenesis assay and the study of systemic neoangiogenesis in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Vascular endothelial growth factor-mediated decrease in plasma soluble vascular endothelial growth factor receptor-2 levels as a surrogate biomarker for tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Control of angiogenesis dictated by picomolar superoxide levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Immunolocalization of VEGF, VEGF receptors, EGF-R and Ki-67 in leiomyoma, cellular leiomyoma and leiomyosarcoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Insulin-like growth factor binding protein-related protein 1 mediates VEGF-induced proliferation, migration and tube formation of retinal endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

PET imaging of tumor angiogenesis in mice with VEGF-A-targeted (86)Y-CHX-A″-DTPA-bevacizumab.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Fibroblast growth factor 2 regulates endothelial cell sensitivity to sunitinib.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Novel antiangiogenic agents in dermatology

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Human endothelial stem/progenitor cells, angiogenic factors and vascular repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Radical causes of cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Overcoming disease-induced growth factor resistance in therapeutic angiogenesis using recombinant co-receptors delivered by a liposomal system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Reactive oxygen species in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Redox regulation of Nox proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Oxidants in mitochondria: from physiology to diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Autophagy, reactive oxygen species and the fate of mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

ROS stress in cancer cells and therapeutic implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Evidence of ROS generation by mitochondria in cells with impaired electron transport chain and mitochondrial DNA damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Editorial: Emerging concepts in the management of prostatitis/chronic pelvic pain syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Reactive oxygen species in oncogenic transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Mitochondrial Oxidative Stress and Mitochondrial DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Persistent oxidative stress in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Free radicals in chemical carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

VEGF signaling through NADPH oxidase-derived ROS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Dual functional roles of Tie-2/angiopoietin in TNF-alpha-mediated angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Superoxide and the production of oxidative DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

The alteration of superoxide dismutase, catalase, glutathione peroxidase, and NAD(P)H cytochrome c reductase in guinea pig polymorphonuclear leukocytes and alveolar macrophages during hyperoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Peroxynitrite-dependent killing of cancer cells and presentation of released tumor antigens by activated dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Ischemic and peroxynitrite preconditioning effects in chronic hypoxic rat lung

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Nitric oxide modulates superoxide release and peroxynitrite formation in human blood vessels

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Superoxide and peroxynitrite in atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

The Haber-Weiss cycle--70 years later

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Protein tyrosine phosphatases: from genes, to function, to disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Inside the human cancer tyrosine phosphatome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Protein tyrosine phosphatases in the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

TCPTP regulates SFK and STAT3 signaling and is lost in triple-negative breast cancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Methods to monitor classical protein-tyrosine phosphatase oxidation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Mechanistic studies on protein tyrosine phosphatases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Redox regulation of protein tyrosine phosphatases: structural and chemical aspects

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Redox redux: revisiting PTPs and the control of cell signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Macrophages, innate immunity and cancer: balance, tolerance, and diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

The involvement of Helicobacter pylori thioredoxin-1 in gastric carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Epidemiologic association between prostatitis and prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Prostatitis as a risk factor for prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

The polarization of immune cells in the tumour environment by TGFbeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Macrophage diversity enhances tumor progression and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Macrophages: Obligate Partners for Tumor Cell Migration, Invasion, and Metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

NADPH oxidases as regulators of tumor angiogenesis: current and emerging concepts

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Ncf1 (p47phox) is essential for direct regulatory T cell mediated suppression of CD4+ effector T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Spontaneous and aging-dependent development of arthritis in NADPH oxidase 2 deficiency through altered differentiation of CD11b+ and Th/Treg cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Role of Oxidative Stress Response Elements and Antioxidants in Prostate Cancer Pathobiology and Chemoprevention -- A Mechanistic Approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Phosphorylation of p47phox sites by PKC alpha, beta II, delta, and zeta: effect on binding to p22phox and on NADPH oxidase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Comparative pharmacology of chemically distinct NADPH oxidase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Antioxidants: benefits and risks for long-term health

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Inhibition of prostate carcinogenesis in TRAMP mice by oral infusion of green tea polyphenols

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

NADPH oxidases in the vasculature: molecular features, roles in disease and pharmacological inhibition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Opportunity nox: the future of NADPH oxidases as therapeutic targets in cardiovascular disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Nox family NADPH oxidases in mechano-transduction: mechanisms and consequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

NADPH oxidase 2 mediates intermittent hypoxia-induced mitochondrial complex I inhibition: relevance to blood pressure changes in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Physiology and pathophysiology of the DUOXes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

NOX2β: A novel splice variant of NOX2 that regulates NADPH oxidase activity in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Identification of novel Nox4 splice variants with impact on ROS levels in A549 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

A 28-kDa splice variant of NADPH oxidase-4 is nuclear-localized and involved in redox signaling in vascular cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Oscillatory and steady laminar shear stress differentially affect human endothelial redox state: role of a superoxide-producing NADH oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

NADPH oxidase-dependent signaling in endothelial cells: role in physiology and pathophysiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

NOX4 activity is determined by mRNA levels and reveals a unique pattern of ROS generation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

NADPH oxidase isoform selective regulation of endothelial cell proliferation and survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Functional association of nox1 with p22phox in vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

In search of new therapeutic targets and strategies for heart failure: recent advances in basic science

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Activation of Rap1 inhibits NADPH oxidase-dependent ROS generation in retinal pigment epithelium and reduces choroidal neovascularization

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Hace1 controls ROS generation of vertebrate Rac1-dependent NADPH oxidase complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

NADPH oxidase 4 mediates insulin-stimulated HIF-1α and VEGF expression, and angiogenesis in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Novel role of gp91(phox)-containing NAD(P)H oxidase in vascular endothelial growth factor-induced signaling and angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Reactive oxygen generated by Nox1 triggers the angiogenic switch

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Nox1 oxidase suppresses influenza a virus-induced lung inflammation and oxidative stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Inhibition of NADPH oxidase activation in endothelial cells by ortho-methoxy-substituted catechols

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Inhibition of NADPH oxidase by apocynin attenuates progression of atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Novel competitive inhibitor of NAD(P)H oxidase assembly attenuates vascular O(2)(-) and systolic blood pressure in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Nox2 B-loop peptide, Nox2ds, specifically inhibits the NADPH oxidase Nox2

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

The quest for selective nox inhibitors and therapeutics: challenges, triumphs and pitfalls

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Pharmacologic blockade of angiopoietin-2 is efficacious against model hemangiomas in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Ebselen and congeners inhibit NADPH oxidase 2-dependent superoxide generation by interrupting the binding of regulatory subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Divergent effects of p47(phox) phosphorylation at S303-4 or S379 on tumor necrosis factor-α signaling via TRAF4 and MAPK in endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

A novel and specific NADPH oxidase-1 (Nox1) small-molecule inhibitor blocks the formation of functional invadopodia in human colon cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

NADPH oxidases as therapeutic targets in ischemic stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

The NOX toolbox: validating the role of NADPH oxidases in physiology and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

The NADPH oxidase inhibitor VAS2870 impairs cell growth and enhances TGF-β-induced apoptosis of liver tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Critical role of Nox4-based NADPH oxidase in glucose-induced oxidative stress in the kidney: implications in type 2 diabetic nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

The Nox4 inhibitor GKT137831 attenuates hypoxia-induced pulmonary vascular cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

S17834, a new inhibitor of cell adhesion and atherosclerosis that targets nadph oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Targeting NADPH oxidases in vascular pharmacology

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Expression of NADPH oxidase homologues and accessory genes in human cancer cell lines, tumours and adjacent normal tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

A novel human AlkB homologue, ALKBH8, contributes to human bladder cancer progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Cross talk between mitochondria and superoxide generating NADPH oxidase in breast and ovarian tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

The NADPH oxidase subunit p22phox inhibits the function of the tumor suppressor protein tuberin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Nox1 expression determines cellular reactive oxygen and modulates c-fos-induced growth factor, interleukin-8, and Cav-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Aiding and abetting roles of NOX oxidases in cellular transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

An NAD(P)H oxidase regulates growth and transcription in melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Oxidative stress is inherent in prostate cancer cells and is required for aggressive phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

NADPH oxidase subunit, gp91(phox) homologue, preferentially expressed in human colon epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

ROS generation via NOX4 and its utility in the cytological diagnosis of urothelial carcinoma of the urinary bladder

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Right-side and left-side colon cancer follow different pathways to relapse

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Intracellular expression of reactive oxygen species-generating NADPH oxidase NOX4 in normal and cancer thyroid tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Activation of androgen receptor, lipogenesis, and oxidative stress converged by SREBP-1 is responsible for regulating growth and progression of prostate cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Expression and activity of NOX5 in the circulating malignant B cells of hairy cell leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Endothelial cell oxidant production: effect of NADPH oxidase inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Chronic administration of the oral hypoglycaemic agent diphenyleneiodonium to rats. An animal model of impaired oxidative phosphorylation (mitochondrial myopathy).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238

Hyperinflammation in chronic granulomatous disease and anti-inflammatory role of the phagocyte NADPH oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12238