(Q38205859)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24749533%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

title

Current status of antifungal resistance and its impact on clinical practice (English)

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14 March 2020

2

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14 March 2020

author name string

Laura Alcazar-Fuoli

series ordinal

1

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14 March 2020

language of work or name

English

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publication date

18 April 2014

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24749533%20AND%20SRC:MED&resulttype=core&format=json

British Journal of Haematology

14 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24749533%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

volume

166

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24749533%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

issue

4

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14 March 2020

page(s)

471-484

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24749533%20AND%20SRC:MED&resulttype=core&format=json

Antifungal susceptibility profile of clinical Fusarium spp. isolates identified by molecular methods.

14 March 2020

cites work

1 reference

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Three-dimensional models of 14α-sterol demethylase (Cyp51A) from Aspergillus lentulus and Aspergillus fumigatus: an insight into differences in voriconazole interaction

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21 January 2018

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Use of lung resection and voriconazole for successful treatment of invasive pulmonary Aspergillus ustus infection.

21 January 2018

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cyp51A-Based mechanisms of Aspergillus fumigatus azole drug resistance present in clinical samples from Germany.

21 January 2018

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Nonsporulating clinical isolate identified as Petromyces alliaceus (anamorph Aspergillus alliaceus) by morphological and sequence-based methods

21 January 2018

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Assessing resistance to the echinocandin antifungal drug caspofungin in Candida albicans by profiling mutations in FKS1

21 January 2018

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Effects of caspofungin against Candida guilliermondii and Candida parapsilosis

21 January 2018

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Echinocandin resistance in Candida species: mechanisms of reduced susceptibility and therapeutic approaches.

21 January 2018

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Invasive fungal infections in acute leukemia

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Potential basis for amphotericin B resistance in Aspergillus terreus

21 January 2018

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Considerations in the approach to invasive fungal infection in patients with haematological malignancies

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21 January 2018

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High prevalence of azole-resistant Aspergillus fumigatus in adults with cystic fibrosis exposed to itraconazole.

21 January 2018

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Management of invasive fungal infections: a role for polyenes

21 January 2018

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Isolation of multiple-triazole-resistant Aspergillus fumigatus strains carrying the TR/L98H mutations in the cyp51A gene in India.

21 January 2018

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Azole-resistant Aspergillus fumigatus with the environmental TR46/Y121F/T289A mutation in India

21 January 2018

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21 January 2018

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Amphotericin B resistance of Aspergillus terreus in a murine model of disseminated aspergillosis.

21 January 2018

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Antibiotics that inhibit fungal cell wall development

21 January 2018

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Echinocandin antifungal drugs

21 January 2018

1 reference

Correlation between in-vitro susceptibility testing to itraconazole and in-vivo outcome of Aspergillus fumigatus infection

21 January 2018

1 reference

Development of echinocandin resistance in Clavispora lusitaniae during caspofungin treatment

21 January 2018

1 reference

A point mutation in the 14alpha-sterol demethylase gene cyp51A contributes to itraconazole resistance in Aspergillus fumigatus

21 January 2018

1 reference

A gain-of-function mutation in the transcription factor Upc2p causes upregulation of ergosterol biosynthesis genes and increased fluconazole resistance in a clinical Candida albicans isolate.

21 January 2018

1 reference

Molecular mechanisms of drug resistance in clinical Candida species isolated from Tunisian hospitals

21 January 2018

1 reference

The evolving role of antifungal susceptibility testing

21 January 2018

1 reference

Caspofungin-resistant Aspergillus flavus after heart transplantation and mechanical circulatory support: a case report.

21 January 2018

1 reference

Wild-type MIC distributions and epidemiological cutoff values for amphotericin B and Aspergillus spp. for the CLSI broth microdilution method (M38-A2 document).

21 January 2018

1 reference

Wild-type MIC distributions and epidemiological cutoff values for caspofungin and Aspergillus spp. for the CLSI broth microdilution method (M38-A2 document).

21 January 2018

1 reference

Contribution of CgPDR1-regulated genes in enhanced virulence of azole-resistant Candida glabrata

21 January 2018

1 reference

Gain-of-function mutations in UPC2 are a frequent cause of ERG11 upregulation in azole-resistant clinical isolates of Candida albicans

21 January 2018

1 reference

Candida tropicalis antifungal cross-resistance is related to different azole target (Erg11p) modifications.

21 January 2018

1 reference

A naturally occurring proline-to-alanine amino acid change in Fks1p in Candida parapsilosis, Candida orthopsilosis, and Candida metapsilosis accounts for reduced echinocandin susceptibility

21 January 2018

1 reference

Effect of Candida glabrata FKS1 and FKS2 mutations on echinocandin sensitivity and kinetics of 1,3-beta-D-glucan synthase: implication for the existing susceptibility breakpoint

21 January 2018

1 reference

Characterization of Aspergillus fumigatus mutants with reduced susceptibility to caspofungin

21 January 2018

1 reference

Scedosporium apiospermum: changing clinical spectrum of a therapy-refractory opportunist*

21 January 2018

1 reference

Amphotericin B in vitro resistance is associated with fatal Aspergillus flavus infection.

21 January 2018

1 reference

Caspofungin first-line therapy for invasive aspergillosis in allogeneic hematopoietic stem cell transplant patients: an European Organisation for Research and Treatment of Cancer study

21 January 2018

1 reference

Multi-azole resistance in Aspergillus fumigatus

21 January 2018

1 reference

Frequency and evolution of Azole resistance in Aspergillus fumigatus associated with treatment failure

21 January 2018

1 reference

Stepwise development of a homozygous S80P substitution in Fks1p, conferring echinocandin resistance in Candida tropicalis.

21 January 2018

1 reference

Antimicrobial resistance: resistance to antifungal agents: mechanisms and clinical impact

21 January 2018

1 reference

Candida dubliniensis: an appraisal of its clinical significance as a bloodstream pathogen

21 January 2018

1 reference

Prospective surveillance for invasive fungal infections in hematopoietic stem cell transplant recipients, 2001-2006: overview of the Transplant-Associated Infection Surveillance Network (TRANSNET) Database.

21 January 2018

1 reference

Amphotericin B and caspofungin resistance in Candida glabrata isolates recovered from a critically ill patient

21 January 2018

1 reference

Abc1p is a multidrug efflux transporter that tips the balance in favor of innate azole resistance in Candida krusei.

21 January 2018

1 reference

Liposomal amphotericin B: what is its role in 2008?

21 January 2018

1 reference

Epidemiology and outcome of infections due to Aspergillus terreus: 10-year single centre experience

21 January 2018

1 reference

Rapid emergence of echinocandin resistance in Candida glabrata resulting in clinical and microbiologic failure.

21 January 2018

1 reference

Aspergillus species intrinsically resistant to antifungal agents.

21 January 2018

1 reference

Clinical implications of azole resistance in Aspergillus fumigatus, The Netherlands, 2007-2009.

21 January 2018

1 reference

Aspergillosis due to voriconazole highly resistant Aspergillus fumigatus and recovery of genetically related resistant isolates from domiciles

21 January 2018

1 reference

Azole resistance in Aspergillus fumigatus isolates from the ARTEMIS global surveillance study is primarily due to the TR/L98H mutation in the cyp51A gene

21 January 2018

1 reference

Species identification and antifungal susceptibility testing of Candida bloodstream isolates from population-based surveillance studies in two U.S. cities from 2008 to 2011.

21 January 2018

1 reference

Distinct roles of Candida albicans drug resistance transcription factors TAC1, MRR1, and UPC2 in virulence

21 January 2018

1 reference

Breakthrough invasive aspergillosis in allogeneic haematopoietic stem cell transplant recipients treated with caspofungin

21 January 2018

1 reference

European guidelines for antifungal management in leukemia and hematopoietic stem cell transplant recipients: summary of the ECIL 3--2009 update

21 January 2018

1 reference

Changing epidemiology of rare mould infections: implications for therapy

21 January 2018

1 reference

Contribution of mutations in the cytochrome P450 14alpha-demethylase (Erg11p, Cyp51p) to azole resistance in Candida albicans

21 January 2018

1 reference

Identification and Characterization of Four Azole-Resistant erg3 Mutants of Candida albicans

21 January 2018

1 reference

Substitutions at methionine 220 in the 14alpha-sterol demethylase (Cyp51A) of Aspergillus fumigatus are responsible for resistance in vitro to azole antifungal drugs

21 January 2018

1 reference

A new Aspergillus fumigatus resistance mechanism conferring in vitro cross-resistance to azole antifungals involves a combination of cyp51A alterations.

21 January 2018

1 reference

Role of Aspergillus lentulus 14-α sterol demethylase (Cyp51A) in azole drug susceptibility.

21 January 2018

1 reference

Resistance to amphotericin B does not emerge during treatment for invasive aspergillosis

21 January 2018

1 reference

Screening for amino acid substitutions in the Candida albicans Erg11 protein of azole-susceptible and azole-resistant clinical isolates: new substitutions and a review of the literature.

21 January 2018

1 reference

Amino acid substitutions in the Candida albicans sterol Δ5,6-desaturase (Erg3p) confer azole resistance: characterization of two novel mutants with impaired virulence

21 January 2018

1 reference

Environmental study of azole-resistant Aspergillus fumigatus and other aspergilli in Austria, Denmark, and Spain

21 January 2018

1 reference

Multiple resistance mechanisms among Aspergillus fumigatus mutants with high-level resistance to itraconazole.

21 January 2018

1 reference

Epidemiology and outcome of invasive fungal infection in adult hematopoietic stem cell transplant recipients: analysis of Multicenter Prospective Antifungal Therapy (PATH) Alliance registry.

21 January 2018

1 reference

Fungal infections in recipients of hematopoietic stem cell transplants: results of the SEIFEM B-2004 study--Sorveglianza Epidemiologica Infezioni Fungine Nelle Emopatie Maligne.

21 January 2018

1 reference

Risk assessment and prognostic factors for mould-related diseases in immunocompromised patients

21 January 2018

1 reference

Breakthrough invasive mould infections in patients treated with caspofungin

21 January 2018

1 reference

Invasive fungal infections among organ transplant recipients: results of the Transplant-Associated Infection Surveillance Network (TRANSNET).

21 January 2018

1 reference

Specific substitutions in the echinocandin target Fks1p account for reduced susceptibility of rare laboratory and clinical Candida sp. isolates

21 January 2018

1 reference

Evaluation of amphotericin B interpretive breakpoints for Candida bloodstream isolates by correlation with therapeutic outcome

21 January 2018

1 reference

Heterologous expression and characterization of the sterol 14α-demethylase CYP51F1 from Candida albicans

21 January 2018

1 reference

Treatment failure in invasive aspergillosis: susceptibility of deep tissue isolates following treatment with amphotericin B.

21 January 2018

1 reference

Resistance to voriconazole due to a G448S substitution in Aspergillus fumigatus in a patient with cerebral aspergillosis

21 January 2018

1 reference

Molecular mechanisms of fluconazole resistance in Candida dubliniensis isolates from human immunodeficiency virus-infected patients with oropharyngeal candidiasis

21 January 2018

1 reference

Resistance to echinocandin-class antifungal drugs

21 January 2018

1 reference

Current perspectives on echinocandin class drugs

21 January 2018

1 reference

Antifungal drug resistance: mechanisms, epidemiology, and consequences for treatment

21 January 2018

1 reference

Progress in antifungal susceptibility testing of Candida spp. by use of Clinical and Laboratory Standards Institute broth microdilution methods, 2010 to 2012

21 January 2018

1 reference

Wild-type MIC distribution and epidemiological cutoff values for Aspergillus fumigatus and three triazoles as determined by the Clinical and Laboratory Standards Institute broth microdilution methods

21 January 2018

1 reference

Results from the ARTEMIS DISK Global Antifungal Surveillance Study, 1997 to 2007: a 10.5-year analysis of susceptibilities of Candida Species to fluconazole and voriconazole as determined by CLSI standardized disk diffusion.

21 January 2018

1 reference

Clinical breakpoints for the echinocandins and Candida revisited: integration of molecular, clinical, and microbiological data to arrive at species-specific interpretive criteria.

21 January 2018

1 reference

Frequency of decreased susceptibility and resistance to echinocandins among fluconazole-resistant bloodstream isolates of Candida glabrata

21 January 2018

1 reference

Molecular mechanisms of itraconazole resistance in Candida dubliniensis

21 January 2018

1 reference

Epidemiology and predictive factors for early and late mortality in Candida bloodstream infections: a population-based surveillance in Spain.

21 January 2018

1 reference

First reported case of azole-resistant aspergillus fumigatus due to the TR/L98H mutation in Germany

21 January 2018

1 reference

A Ser678Pro substitution in Fks1p confers resistance to echinocandin drugs in Aspergillus fumigatus

21 January 2018

1 reference

Epidemiological cutoffs and cross-resistance to azole drugs in Aspergillus fumigatus.

21 January 2018

1 reference

Clinical relevance of resistance to antifungals.

21 January 2018

1 reference

Azole-resistant Aspergillus fumigatus, Iran.

21 January 2018

1 reference

Emerging fungal infections in solid organ transplant recipients

21 January 2018

1 reference

Transcriptional profiling of azole-resistant Candida parapsilosis strains

21 January 2018

1 reference

Emergence of azole resistance in Aspergillus fumigatus and spread of a single resistance mechanism

21 January 2018

1 reference

Possible environmental origin of resistance of Aspergillus fumigatus to medical triazoles

21 January 2018

1 reference

Differential Aspergillus lentulus echinocandin susceptibilities are Fksp independent

21 January 2018

1 reference

Infections due to Aspergillus terreus: a multicenter retrospective analysis of 83 cases

21 January 2018

1 reference

Studies of the paradoxical effect of caspofungin at high drug concentrations

21 January 2018

1 reference

Mechanisms of Candida biofilm drug resistance

21 January 2018

1 reference

Epidemiology of candidaemia in Europe: results of 28-month European Confederation of Medical Mycology (ECMM) hospital-based surveillance study.

21 January 2018

1 reference

ESCMID* guideline for the diagnosis and management of Candida diseases 2012: adults with haematological malignancies and after haematopoietic stem cell transplantation (HCT).

21 January 2018

1 reference

Mechanisms of azole resistance in a clinical isolate of Candida tropicalis

21 January 2018

1 reference

Azole-resistance in Aspergillus: proposed nomenclature and breakpoints

21 January 2018

1 reference

An EORTC Phase II study of caspofungin as first-line therapy of invasive aspergillosis in haematological patients

21 January 2018

1 reference

Fungal echinocandin resistance.

21 January 2018

1 reference

Treatment of fungal disease in the setting of neutropenia

21 January 2018

1 reference

Treatment of aspergillosis: clinical practice guidelines of the Infectious Diseases Society of America

21 January 2018

1 reference

Nosocomial bloodstream infections due to Candida spp. in the USA: species distribution, clinical features and antifungal susceptibilities

21 January 2018

1 reference

Single ionic channels induced in lipid bilayers by polyene antibiotics amphotericin B and nystatine

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1111/BJH.12896

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24749533%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

1 reference