(Q38206114)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24752371%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

title

Molecular mechanisms in autoimmune type 1 diabetes: a critical review (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24752371%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

0 references

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24752371%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

author name string

Zhiguo Xie

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24752371%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

Christopher Chang

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24752371%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

publication date

1 October 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24752371%20AND%20SRC:MED&resulttype=core&format=json

Clinical Reviews in Allergy & Immunology

14 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24752371%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

volume

47

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24752371%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24752371%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

page(s)

174-192

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24752371%20AND%20SRC:MED&resulttype=core&format=json

Incidence trends for childhood type 1 diabetes in Europe during 1989-2003 and predicted new cases 2005-20: a multicentre prospective registration study

14 March 2020

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The Variable Number of Tandem Repeats Upstream of the Insulin Gene Is a Susceptibility Locus for Latent Autoimmune Diabetes in Adults

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Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes

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A genome-wide association study of nonsynonymous SNPs identifies a type 1 diabetes locus in the interferon-induced helicase (IFIH1) region

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21 January 2018

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21 January 2018

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Conditional meta-analysis stratifying on detailed HLA genotypes identifies a novel type 1 diabetes locus around TCF19 in the MHC

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Histocompatibility (HL-A) Antigens, Lymphocytotoxic Antibodies and Tissue Antibodies in Patients with Diabetes Mellitus

21 January 2018

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The genetic basis for type 1 diabetes

21 January 2018

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Gene map of the extended human MHC.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Replication of an association between the lymphoid tyrosine phosphatase locus (LYP/PTPN22) with type 1 diabetes, and evidence for its role as a general autoimmunity locus

21 January 2018

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Genetics of autoimmune diseases--disorders of immune homeostasis

21 January 2018

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Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant

21 January 2018

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Gaining insight into PTPN22 and autoimmunity

21 January 2018

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PTPN22: its role in SLE and autoimmunity

21 January 2018

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The putative role of the C1858T polymorphism of protein tyrosine phosphatase PTPN22 gene in autoimmunity.

21 January 2018

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The role of PTPN22 in autoimmunity: learning from mice

21 January 2018

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How do regulatory T cells work?

21 January 2018

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Enhanced killing activity of regulatory T cells ameliorates inflammation and autoimmunity

21 January 2018

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Assessing the validity of the association between the SUMO4 M55V variant and risk of type 1 diabetes

21 January 2018

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Proteomic analysis of SUMO4 substrates in HEK293 cells under serum starvation-induced stress

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STAT4 polymorphism is associated with early-onset type 1 diabetes, but not with late-onset type 1 diabetes.

21 January 2018

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Stat4 is expressed in activated peripheral blood monocytes, dendritic cells, and macrophages at sites of Th1-mediated inflammation

21 January 2018

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Autoimmune diabetes is blocked in Stat4-deficient mice

21 January 2018

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Genetic heterogeneity in latent autoimmune diabetes is linked to various degrees of autoimmune activity: results from the Nord-Trøndelag Health Study

21 January 2018

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Genetic analysis of adult-onset autoimmune diabetes

21 January 2018

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HLA-DR, HLA-DQB1 and PTPN22 gene polymorphism: association with age at onset for autoimmune diabetes

21 January 2018

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Concordance for type 1 (insulin-dependent) and type 2 (non-insulin-dependent) diabetes mellitus in a population-based cohort of twins in Finland

21 January 2018

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21 January 2018

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Temporal changes in the frequencies of HLA genotypes in patients with Type 1 diabetes--indication of an increased environmental pressure?

21 January 2018

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21 January 2018

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Less travelled roads in clinical immunology and allergy: drug reactions and the environmental influence

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Autoimmune diseases and polyamines

21 January 2018

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Hygiene hypothesis and autoimmune diseases

21 January 2018

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Environmental contaminants as etiologic factors for diabetes

21 January 2018

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What is the role of human contamination by environmental chemicals in the development of type 1 diabetes?

21 January 2018

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Psychological stress and the risk of diabetes-related autoimmunity: a review article

21 January 2018

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Birth weight, early weight gain, and subsequent risk of type 1 diabetes: systematic review and meta-analysis

21 January 2018

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Enterovirus infection and type 1 diabetes mellitus: systematic review and meta-analysis of observational molecular studies

21 January 2018

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Enterovirus RNA in blood is linked to the development of type 1 diabetes

21 January 2018

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Enterovirus infection and progression from islet autoimmunity to type 1 diabetes: the Diabetes and Autoimmunity Study in the Young (DAISY)

21 January 2018

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The critical importance of epigenetics in autoimmunity

21 January 2018

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Epigenetic modifications and human disease

21 January 2018

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Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA

21 January 2018

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DNA methylation patterns and epigenetic memory

21 January 2018

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Active DNA demethylation: many roads lead to Rome.

21 January 2018

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The epigenetic bottleneck of neurodegenerative and psychiatric diseases

21 January 2018

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DNA methylation and human disease

21 January 2018

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Identification of type 1 diabetes-associated DNA methylation variable positions that precede disease diagnosis.

21 January 2018

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DNA methylation impairs TLR9 induced Foxp3 expression by attenuating IRF-7 binding activity in fulminant type 1 diabetes

21 January 2018

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Association of the CpG methylation pattern of the proximal insulin gene promoter with type 1 diabetes

21 January 2018

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Detection of β cell death in diabetes using differentially methylated circulating DNA.

21 January 2018

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Detection of islet β-cell death in vivo by multiplex PCR analysis of differentially methylated DNA.

21 January 2018

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The language of covalent histone modifications

21 January 2018

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Epigenetic differences arise during the lifetime of monozygotic twins

21 January 2018

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Lab-on-a-chip: emerging analytical platforms for immune-mediated diseases

21 January 2018

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Lymphocytes from patients with type 1 diabetes display a distinct profile of chromatin histone H3 lysine 9 dimethylation: an epigenetic study in diabetes

21 January 2018

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The evolution of gene regulation by transcription factors and microRNAs

21 January 2018

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Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?

21 January 2018

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The role of miRNA in inflammation and autoimmunity

21 January 2018

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MicroRNAs in autoimmunity and inflammatory bowel disease: crucial regulators in immune response

21 January 2018

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MicroRNAs in β-cell biology, insulin resistance, diabetes and its complications

21 January 2018

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Increased expression of microRNA miR-326 in type 1 diabetic patients with ongoing islet autoimmunity

21 January 2018

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MicroRNAs miR-21a and miR-93 are down regulated in peripheral blood mononuclear cells (PBMCs) from patients with type 1 diabetes

21 January 2018

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The microRNA-21-PDCD4 axis prevents type 1 diabetes by blocking pancreatic beta cell death

21 January 2018

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Potential role of human-specific genes, human-specific microRNAs and human-specific non-coding regulatory RNAs in the pathogenesis of systemic sclerosis and Sjögren's syndrome

21 January 2018

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The therapeutic potential of epigenetics in autoimmune diseases.

21 January 2018

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The role of viruses in human diabetes.

21 January 2018

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Viral infections and molecular mimicry in type 1 diabetes

21 January 2018

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Molecular mimicry and auto-immunity

21 January 2018

1 reference

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Cellular immunity to a determinant common to glutamate decarboxylase and coxsackie virus in insulin-dependent diabetes

21 January 2018

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Molecular mimicry as a mechanism of autoimmune disease

21 January 2018

1 reference

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Enterovirus infection can induce immune responses that cross-react with beta-cell autoantigen tyrosine phosphatase IA-2/IAR.

21 January 2018

1 reference

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Cytomegalovirus in autoimmunity: T cell crossreactivity to viral antigen and autoantigen glutamic acid decarboxylase

21 January 2018

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Immune mechanisms that regulate susceptibility to autoimmune type I diabetes

21 January 2018

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Novel autoantigens for diabetogenic CD4 T cells in autoimmune diabetes

21 January 2018

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Improved T cell assay for identification of type 1 diabetes patients

21 January 2018

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Autoimmune mechanisms in type 1 diabetes

21 January 2018

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What causes relapses of autoimmune diseases? The etiological role of autoreactive T cells

21 January 2018

1 reference

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Molecular targeting of islet autoantigens

21 January 2018

1 reference

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Is autoimmune diabetes caused by aberrant immune activity or defective suppression of physiological self-reactivity?

21 January 2018

1 reference

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The clinical and immunological significance of GAD-specific autoantibody and T-cell responses in type 1 diabetes.

21 January 2018

1 reference

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Autoantigens IA-2 and GAD in Type I (insulin-dependent) diabetes

21 January 2018

1 reference

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The cation efflux transporter ZnT8 (Slc30A8) is a major autoantigen in human type 1 diabetes

21 January 2018

1 reference

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Islet-cell antibodies in diabetes mellitus with autoimmune polyendocrine deficiencies

21 January 2018

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Autoantibodies in type 1 diabetes.

21 January 2018

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The diagnostic value of zinc transporter 8 autoantibody (ZnT8A) for type 1 diabetes in Chinese.

21 January 2018

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Autoantibodies in diabetes

21 January 2018

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Role of autoantibodies in type 1 diabetes

21 January 2018

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The HLA class I A locus affects susceptibility to type 1 diabetes

21 January 2018

1 reference

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HLA class I and genetic susceptibility to type 1 diabetes: results from the Type 1 Diabetes Genetics Consortium

21 January 2018

1 reference

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Genome-wide DNA methylation study suggests epigenetic accessibility and transcriptional poising of interferon-regulated genes in naïve CD4+ T cells from lupus patients

21 January 2018

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Genetic susceptibility to SLE: recent progress from GWAS.

21 January 2018

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In silico replication of the genome-wide association results of the Type 1 Diabetes Genetics Consortium.

21 January 2018

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Copy number variation in the human genome and its implication in autoimmunity

21 January 2018

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Genome-wide analysis of copy number variation in type 1 diabetes

21 January 2018

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MicroRNAs: new regulators of immune cell development and function

21 January 2018

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MicroRNA in autoimmunity and autoimmune diseases.

21 January 2018

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MicroRNA, a new paradigm for understanding immunoregulation, inflammation, and autoimmune diseases

21 January 2018

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Antigen-specific immunomodulation for type 1 diabetes by novel recombinant antibodies directed against diabetes-associates auto-reactive T cell epitope

21 January 2018

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Posttranslational modifications of proteins in type 1 diabetes: the next step in finding the cure?

21 January 2018

1 reference

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Changing faces, unmasking the beta-cell: post-translational modification of antigens in type 1 diabetes

21 January 2018

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The insulin A-chain epitope recognized by human T cells is posttranslationally modified

21 January 2018

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Do post-translational beta cell protein modifications trigger type 1 diabetes?

21 January 2018

1 reference

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Is there evidence for post-translational modification of beta cell autoantigens in the aetiology and pathogenesis of type 1 diabetes?

21 January 2018

1 reference

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Destabilization of peptide:MHC interaction induces IL-2 resistant anergy in diabetogenic T cells

21 January 2018

1 reference

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Promotion and prevention of autoimmune disease by CD8+ T cells

21 January 2018

1 reference

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Is the origin of type 1 diabetes in the gut?

21 January 2018

1 reference

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Gut microbiota, immunity, and disease: a complex relationship

21 January 2018

1 reference

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Rethinking mechanisms of autoimmune pathogenesis

21 January 2018

1 reference

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Gut microbiota in children with type 1 diabetes differs from that in healthy children: a case-control study

21 January 2018

1 reference

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Induction of intestinal Th17 cells by segmented filamentous bacteria

21 January 2018

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Regulatory properties of the intestinal microbiome effecting the development and treatment of diabetes

21 January 2018

1 reference

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Human intestinal microbiota and type 1 diabetes

21 January 2018

1 reference

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The CTLA-4 gene region of chromosome 2q33 is linked to, and associated with, type 1 diabetes. Belgian Diabetes Registry

21 January 2018

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21 January 2018

12 December 2020

Genetics of type 1 diabetes in Asian and Caucasian populations

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Susceptibility to human type 1 diabetes at IDDM2 is determined by tandem repeat variation at the insulin gene minisatellite locus

21 January 2018

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Infant feeding and the risk of type 1 diabetes.

21 January 2018

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12 December 2020

Nutritional risk predictors of beta cell autoimmunity and type 1 diabetes at a young age

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12 December 2020

A case of slowly progressive type 1 diabetes with insulin independence maintained for 10 years with α-glucosidase inhibitor monotherapy

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12 December 2020

Reevaluation of human leukocyte antigen DR-DQ haplotype and genotype in type 1 diabetes in the Japanese population

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Common susceptibility and transmission pattern of human leukocyte antigen DRB1-DQB1 haplotypes to Korean and Caucasian patients with type 1 diabetes.

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12 December 2020

The gut immune system and type 1 diabetes

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12 December 2020

The carriage of the type 1 diabetes-associated R262W variant of human LNK correlates with increased proliferation of peripheral blood monocytes in diabetic patients

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12 December 2020

Genetic analysis of HLA class II alleles and susceptibility to type 1 (insulin-dependent) diabetes mellitus in Japanese subjects

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12 December 2020

HLA-DQ, DR allele polymorphism of type 1 diabetes in the Chinese population: a meta-analysis.

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12 December 2020

Combinations of HLA DR and DQ molecules determine the susceptibility to insulin-dependent diabetes mellitus in Koreans

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12 December 2020

Interleukin-12: a cytokine produced by antigen-presenting cells with immunoregulatory functions in the generation of T-helper cells type 1 and cytotoxic lymphocytes

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12 December 2020

HLA-encoded susceptibility to insulin-dependent diabetes mellitus is determined by DR and DQ genes as well as their linkage disequilibria in a Chinese population

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12 December 2020

DNA methylation profiles in type 1 diabetes twins point to strong epigenetic effects on etiology

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12 December 2020

Novel autoantigens in type 1 diabetes

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12 December 2020

CD8 T-cell reactivity to islet antigens is unique to type 1 while CD4 T-cell reactivity exists in both type 1 and type 2 diabetes

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12 December 2020

Molecular mimicry in type 1 diabetes mellitus revisited: T-cell clones to GAD65 peptides with sequence homology to Coxsackie or proinsulin peptides do not crossreact with homologous counterpart

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12 December 2020

Genome-wide DNA methylation analysis for diabetic nephropathy in type 1 diabetes mellitus

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12 December 2020

HLA associations in type 1 diabetes among patients not carrying high-risk DR3-DQ2 or DR4-DQ8 haplotypes

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12 December 2020

Polymorphisms in chromosome region 12q13 and their influence on age at onset of type 1 diabetes

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12 December 2020

Class III alleles of the variable number of tandem repeat insulin polymorphism associated with silencing of thymic insulin predispose to type 1 diabetes

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12 December 2020

The rising incidence of childhood type 1 diabetes and reduced contribution of high-risk HLA haplotypes

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12 December 2020

The role of HLA class II genes in insulin-dependent diabetes mellitus: molecular analysis of 180 Caucasian, multiplex families

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12 December 2020

Variation and trends in incidence of childhood diabetes in Europe. EURODIAB ACE Study Group

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A Polymorphic Locus Near the Human Insulin Gene Is Associated with Insulin-dependent Diabetes Melliitus

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12 December 2020

Association analysis of the AIRE and insulin genes in Finnish type 1 diabetic patients

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12 December 2020

Transmission of DQ haplotypes to patients with type 1 diabetes

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12 December 2020

Latent autoimmune diabetes in adults: a guide for the perplexed

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12 December 2020

Number of autoantibodies (against insulin, GAD or ICA512/IA2) rather than particular autoantibody specificities determines risk of type I diabetes

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12 December 2020

Assessing the role of HLA-linked and unlinked determinants of disease

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12 December 2020

Infant diets and type 1 diabetes: too early, too late, or just too complicated?

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12 December 2020

Mortality in patients with childhood-onset type 1 diabetes in Finland, Estonia, and Lithuania: follow-up of nationwide cohorts

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12 December 2020

Genetic effects on age-dependent onset and islet cell autoantibody markers in type 1 diabetes

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12 December 2020

Asian-specific HLA haplotypes reveal heterogeneity of the contribution of HLA-DR and -DQ haplotypes to susceptibility to type 1 diabetes

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12 December 2020

Association between rotavirus infection and pancreatic islet autoimmunity in children at risk of developing type 1 diabetes

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12 December 2020

Antigen targets of type 1 diabetes autoimmunity

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12 December 2020

Insulin autoantibody could help to screen latent autoimmune diabetes in adults in phenotypic type 2 diabetes mellitus in Chinese

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12 December 2020

A comparison of childhood and adult type I diabetes mellitus

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12 December 2020

Environmental triggers and epigenetic deregulation in autoimmune disease

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12 December 2020

Type 1 diabetes and measles, mumps and rubella childhood infections within the Italian Insulin-dependent Diabetes Registry

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12 December 2020

Epigenetic alterations and microRNA misexpression in cancer and autoimmune diseases: a critical review.

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12 December 2020

microRNA-342, microRNA-191 and microRNA-510 are differentially expressed in T regulatory cells of type 1 diabetic patients

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Type 1 diabetes and LADA--occurrence of HLA-DRB1 *03 and DRB1 *04 alleles in two age different groups of diabetics.

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12 December 2020

Insulin Antibodies in Insulin-Dependent Diabetics Before Insulin Treatment

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HLA in Czech adult patients with autoimmune diabetes mellitus: comparison with Czech children with type 1 diabetes and patients with type 2 diabetes

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Mechanisms and pathophysiology of autoimmune disease

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Cytomegalovirus infection in early infancy: risk of induction and progression of autoimmunity associated with type 1 diabetes

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Heterogeneity of type I diabetes: analysis of monozygotic twins in Great Britain and the United States

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12 December 2020

From Type 1, through LADA, to type 2 diabetes: a continuous spectrum?

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Circulating levels of microRNA from children with newly diagnosed type 1 diabetes and healthy controls: evidence that miR-25 associates to residual beta-cell function and glycaemic control during disease progression.

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10.1007/S12016-014-8422-2

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24752371%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

14 March 2020

1049633004

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24752371%20AND%20SRC:MED&resulttype=core&format=json