(Q38206945)

31 August 2017

title

The pathogenesis and diagnosis of systemic lupus erythematosus: still not resolved (English)

1 reference

systemic lupus erythematosus

31 August 2017

0 references

0 references

1

Ole Petter Rekvig

1 reference

31 August 2017

Johan Van der Vlag

2

1 reference

31 August 2017

publication date

25 April 2014

1 reference

Seminars in Immunopathology

31 August 2017

published in

1 reference

31 August 2017

volume

36

1 reference

31 August 2017

issue

3

1 reference

31 August 2017

page(s)

301-311

1 reference

https://scigraph.springernature.com/pub.10.1007/s00281-014-0428-6

31 August 2017

exact match

0 references

cites work

Developments in the scientific understanding of lupus

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

The role of cell death in the pathogenesis of autoimmune disease: HMGB1 and microparticles as intercellular mediators of inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Cisplatin nephrotoxicity is mediated by deoxyribonuclease I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Role of nucleosomes for induction and glomerular binding of autoantibodies in lupus nephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Cr2, a candidate gene in the murine Sle1c lupus susceptibility locus, encodes a dysfunctional protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Genetic modifiers of systemic lupus erythematosus in FcgammaRIIB(-/-) mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Toll-like receptor 9-dependent and -independent dendritic cell activation by chromatin-immunoglobulin G complexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Apoptosis and NET formation in the pathogenesis of SLE.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Cleavage by granzyme B is strongly predictive of autoantigen status: implications for initiation of autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

The pathogenesis of systemic lupus erythematosus—an update

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Molecular mimicry: can epitope mimicry induce autoimmune disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Alpha-actinin is a cross-reactive renal target for pathogenic anti-DNA antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

A model for lupus brain disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Deranged removal of apoptotic cells: its role in the genesis of lupus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Triggers for anti-chromatin autoantibody production in SLE.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Posttranslational modifications of self-antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Yaa autoimmune phenotypes are conferred by overexpression of TLR7.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Anti-dsDNA antibodies promote initiation, and acquired loss of renal Dnase1 promotes progression of lupus nephritis in autoimmune (NZBxNZW)F1 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Circulating chromatin-anti-chromatin antibody complexes bind with high affinity to dermo-epidermal structures in murine and human lupus nephritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Impact of the tumor necrosis factor receptor-associated protein 1 (Trap1) on renal DNaseI shutdown and on progression of murine and human lupus nephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

T cells and B cells in lupus nephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Mouse dendritic cells matured by ingestion of apoptotic blebs induce T cells to produce interleukin-17.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

IL-17 and the Th17 lineage in systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Induction of immune-mediated glomerulonephritis in normal mice immunized with bacterial DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Deposition of nucleosomal antigens (histones and DNA) in the epidermal basement membrane in human lupus nephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

The genetics of lupus: a functional perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Anti-dsDNA antibodies and disease classification in antinuclear antibody positive patients: the role of analytical diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Heparin exerts a dual effect on murine lupus nephritis by enhancing enzymatic chromatin degradation and preventing chromatin binding in glomerular membranes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Chromatin as a target antigen in human and murine lupus nephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Impaired phagocytosis of apoptotic cell material by monocyte-derived macrophages from patients with systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

RNA polymerase II collision interrupts convergent transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Immunity and behavior: antibodies alter emotion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

The origin, sequence, structure, and consequences of developing anti-DNA antibodies. A human perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Fifty years of anti-ds DNA antibodies: are we approaching journey's end?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Autoimmune accelerating genes, lpr and Yaa, in murine systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Anti-DNA antibodies: aspects of structure and pathogenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Nephritogenic lupus antibodies recognize glomerular basement membrane-associated chromatin fragments released from apoptotic intraglomerular cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Functional and modelling studies of the binding of human monoclonal anti-DNA antibodies to DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Neutrophils in the pathogenesis and manifestations of SLE

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Anti-DNA autoantibodies initiate experimental lupus nephritis by binding directly to the glomerular basement membrane in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Inefficient clearance of dying cells in patients with SLE: anti-dsDNA autoantibodies, MFG-E8, HMGB-1 and other players.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Polyspecific monoclonal lupus autoantibodies reactive with both polynucleotides and phospholipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Neutrophils activate plasmacytoid dendritic cells by releasing self-DNA-peptide complexes in systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Nephritogenic autoantibodies in lupus: current concepts and continuing controversies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Decreased phagocytosis of apoptotic cells in diseased SLE mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Taming lupus-a new understanding of pathogenesis is leading to clinical advances

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

The use of glucocorticoids in systemic lupus erythematosus. After 60 years still more an art than science

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Cross-reactivity and pathogenicity of anti-DNA autoantibodies in systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Global trends, potential mechanisms and early detection of organ damage in SLE.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

The humanistic and economic burden of systemic lupus erythematosus : a systematic review

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Nucleosomes possess a high affinity for glomerular laminin and collagen IV and bind nephritogenic antibodies in murine lupus-like nephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

In vivo expression of a single viral DNA-binding protein generates systemic lupus erythematosus-related autoimmunity to double-stranded DNA and histones

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Lupus nephritis: the central role of nucleosomes revealed

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Nephritogenic potential of anti-DNA antibodies against necrotic nucleosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Lupus anti-DNA autoantibodies cross-react with a glomerular structural protein: a case for tissue injury by molecular mimicry

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Autoimmunity and chronic inflammation - two clearance-related steps in the etiopathogenesis of SLE.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

The role of defective clearance of apoptotic cells in systemic autoimmunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Apoptosis in the pathogenesis of systemic lupus erythematosus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Identification of a cross-reactive self ligand in virus-mediated autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Derivation and validation of the Systemic Lupus International Collaborating Clinics classification criteria for systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Antinuclear antibodies in rheumatic disease: a proposal for a function-based classification

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Autoreactive B cell responses to RNA-related antigens due to TLR7 gene duplication

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

On silico peptide microarrays for high-resolution mapping of antibody epitopes and diverse protein-protein interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

The treatment of systemic lupus proliferative nephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Immunization with a peptide surrogate for double-stranded DNA (dsDNA) induces autoantibody production and renal immunoglobulin deposition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Systemic lupus erythematosus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Pathogenic autoantibodies are routinely generated during the response to foreign antigen: a paradigm for autoimmune disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Experimental expression in mice and spontaneous expression in human SLE of polyomavirus T-antigen. A molecular basis for induction of antibodies to DNA and eukaryotic transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Anti-double-stranded DNA antibodies, nucleosomes, and systemic lupus erythematosus: a time for new paradigms?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Type I interferon and lupus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Endogenous circulating DNA in systemic lupus erythematosus. Occurrence as multimeric complexes bound to histone

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Acquired loss of renal nuclease activity is restricted to DNaseI and is an organ-selective feature in murine lupus nephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Lupus nephritis: enigmas, conflicting models and an emerging concept

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Progression of murine lupus nephritis is linked to acquired renal Dnase1 deficiency and not to up-regulated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Transcriptional interference--a crash course

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Transcriptional elongation control by RNA polymerase II: a new frontier

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Anti-DNA antibodies from autoimmune mice arise by clonal expansion and somatic mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

21 January 2018

Immunochemistry of DNA.

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Expression of the Epstein-Barr virus nuclear antigen-1 (EBNA-1) in the mouse can elicit the production of anti-dsDNA and anti-Sm antibodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

The 1982 revised criteria for the classification of systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Silencing of renal DNaseI in murine lupus nephritis imposes exposure of large chromatin fragments and activation of Toll like receptors and the Clec4e

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Both IgM and IgG anti-DNA antibodies are the products of clonally selective B cell stimulation in (NZB x NZW)F1 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Systemic lupus erythematosus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Induction of inflammatory and immune responses by HMGB1-nucleosome complexes: implications for the pathogenesis of SLE

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Posttranslational protein modifications, apoptosis, and the bypass of tolerance to autoantigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Death, autoantigen modifications, and tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Apoptosis-associated acetylation on histone H2B is an epitope for lupus autoantibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Apoptosis-induced histone H3 methylation is targeted by autoantibodies in systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Glomerular targets of nephritogenic autoantibodies in systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Glomerular binding of anti-dsDNA autoantibodies: the dispute resolved?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Lupus nephritis: role of antinucleosome autoantibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Autoimmunity to nucleosomes related to viral infection: a focus on hapten-carrier complex formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

A relationship between the helical twist of DNA and the ordered positioning of nucleosomes in all eukaryotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Avidity of anti-DNA antibodies in serum and IgG glomerular eluates from patients with systemic lupus erythematosus. Association of high avidity antinative DNA antibody with glomerulonephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Use of a novel elution regimen reveals the dominance of polyreactive antinuclear autoantibodies in lupus kidneys

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Reduced fragmentation of apoptotic chromatin is associated with nephritis in lupus-prone (NZB x NZW)F(1) mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Renal Dnase1 enzyme activity and protein expression is selectively shut down in murine and human membranoproliferative lupus nephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Apoptosis-induced acetylation of histones is pathogenic in systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

RNA polymerase II Transcript Elongation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

The classification of glomerulonephritis in systemic lupus erythematosus revisited

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

The role of clonal selection and somatic mutation in autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0428-6

Specificity and immunochemical properties of antibodies to bacterial DNA

21 January 2018

1 reference

12 December 2020

Murine monoclonal anti-DNA autoantibodies bind to endogenous bacteria.

1 reference

12 December 2020

Histone-specific Th0 and Th1 clones derived from systemic lupus erythematosus patients induce double-stranded DNA antibody production

1 reference

12 December 2020

Pathophysiology of lupus nephritis: the role of nucleosomes

1 reference

12 December 2020

Lupus nephritis: assessing the evidence, considering the future

1 reference

12 December 2020

Inefficient clearance of dying cells and autoreactivity.

1 reference

12 December 2020

A comparison of anti-DNA antibodies from serum and kidney eluates of NZB x NZW F1 mice

1 reference

12 December 2020

Autoimmunity against nucleosomes and lupus nephritis

1 reference

12 December 2020

Analysis of B/W-DNA 16 V(H) gene expression following DNA-peptide immunization

1 reference

12 December 2020

Visualization of the bent helix in kinetoplast DNA by electron microscopy

1 reference

12 December 2020

Exposure of chromatin and not high affinity for dsDNA determines the nephritogenic impact of anti-dsDNA antibodies in (NZBxNZW)F1 mice

1 reference

12 December 2020

Expression of an anti-DNA-associated VH gene in immunized and autoimmune mice

1 reference

12 December 2020

Motheaten, an Immunodeficient Mutant of the Mouse: I. Genetics and pathology

1 reference

12 December 2020

Critical comparative analyses of anti-alpha-actinin and glomerulus-bound antibodies in human and murine lupus nephritis

1 reference

12 December 2020

Responsiveness of autoimmune and normal mice to nucleic acid antigens

1 reference

12 December 2020

Anti-DNA and anti-nucleosome antibody affinity--a mirror image of lupus nephritis?

1 reference

12 December 2020

Human IgG anti-DNA antibodies deposit in kidneys and induce proteinuria in SCID mice

1 reference

12 December 2020

Glomerular apoptotic nucleosomes are central target structures for nephritogenic antibodies in human SLE nephritis

1 reference

12 December 2020

Treatment with a laminin-derived peptide suppresses lupus nephritis

1 reference

12 December 2020

Antigen-binding diversity and idiotypic cross-reactions among hybridoma autoantibodies to DNA

1 reference

12 December 2020

1 reference

12 December 2020

Significance of anti-nuclear and anti-extracellular matrix autoantibodies for albuminuria in murine lupus nephritis; a longitudinal study on plasma and glomerular eluates in MRL/l mice

1 reference

12 December 2020

Pure anti-dsDNA mAbs need chromatin structures to promote glomerular mesangial deposits in BALB/c mice

1 reference

12 December 2020

DNA-binding antibodies from viable motheaten mutant mice: implications for B cell tolerance

1 reference

12 December 2020

Lupus nephritis: consequence of disturbed removal of apoptotic cells?

1 reference

12 December 2020

Antigen-specific induction of antibodies against native mammalian DNA in nonautoimmune mice

1 reference

12 December 2020

Induction of anti-double stranded DNA antibodies in normal mice by immunization with bacterial DNA

1 reference

12 December 2020

Two induced anti-Z-DNA monoclonal antibodies use VH gene segments related to those of anti-DNA autoantibodies.

1 reference

12 December 2020

Molecular mimicry and autoimmune disease

1 reference

12 December 2020

Induction of various autoantibodies by mutant gene lpr in several strains of mice

1 reference

12 December 2020

Development of Autoantibodies before the Clinical Onset of Systemic Lupus Erythematosus

1 reference

12 December 2020

A murine nephritogenic monoclonal anti-DNA autoantibody binds directly to mouse laminin, the major non-collagenous protein component of the glomerular basement membrane

1 reference

12 December 2020

Specificity and immunochemical properties of antibodies to bacterial DNA in sera of normal human subjects and patients with systemic lupus erythematosus (SLE)

1 reference

12 December 2020

Both early and late apoptotic blebs are taken up by DC and induce IL-6 production

1 reference

12 December 2020

Antigen specificity of anti-nuclear antibodies complexed to nucleosomes determines glomerular basement membrane binding in vivo

1 reference

12 December 2020

Netting neutrophils are major inducers of type I IFN production in pediatric systemic lupus erythematosus

1 reference

12 December 2020

Lupus-derived monoclonal autoantibodies against apoptotic chromatin recognize acetylated conformational epitopes

1 reference

12 December 2020

10.1007/S00281-014-0428-6

Identifiers

DOI

1 reference

Dimensions Publication ID

31 August 2017

1022121713

0 references

1 reference