(Q38207936)

31 August 2017

Agonistic autoantibodies directed against G-protein-coupled receptors and their relationship to cardiovascular diseases (English)

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G protein-coupled receptor

31 August 2017

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autoantibody

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inferred from title

cardiovascular disease

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1

Gerd Wallukat

1 reference

31 August 2017

2

Ingolf Schimke

1 reference

PubMed ID

24777744

31 August 2017

language of work or name

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29 April 2014

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Seminars in Immunopathology

31 August 2017

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31 August 2017

36

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31 August 2017

3

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31 August 2017

351-363

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https://scigraph.springernature.com/pub.10.1007/s00281-014-0425-9

31 August 2017

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cites work

Receptor-activating autoantibodies and disease: preeclampsia and beyond

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Targeting anti-beta-1-adrenergic receptor antibodies for dilated cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Activating autoantibodies and cardiovascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Effect of chagasic sera on the rat isolated atrial preparation: immunological, morphological and function aspects

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Autoantibodies to β2-Adrenergic Receptors: a Possible Cause of Adrenergic Hyporesponsiveness in Allergic Rhinitis and Asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Location and nature of the residues important for ligand recognition in G-protein coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Ligand-specific conformation of extracellular loop-2 in the angiotensin II type 1 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

In vitro effects of reactive O2 species on the β-receptor-adenylyl cyclase system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Maternal autoantibodies from preeclamptic patients activate angiotensin receptors on human trophoblast cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Anti-peptide antibodies sensitive to the 'active' state of the beta2-adrenergic receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Molecular mechanisms of anti-G-protein-coupled receptor autoantibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

A peptide derived from a beta2-adrenergic receptor transmembrane domain inhibits both receptor dimerization and activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Agonist-induced increase in apparent β-adrenergic receptor size

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Renal ischemia and transplantation predispose to vascular constriction mediated by angiotensin II type 1 receptor-activating antibodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Autoantibodies against the beta1 adrenoceptor from patients with dilated cardiomyopathy prolong action potential duration and enhance contractility in isolated cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Agonistic anti-beta1-adrenergic receptor autoantibodies from cardiomyopathy patients reduce the beta1-adrenergic receptor expression in neonatal rat cardiomyocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Beta1-adrenoceptor antibodies induce apoptosis in adult isolated cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Aptamer neutralization of beta1-adrenoceptor autoantibodies isolated from patients with cardiomyopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Peptides derived from cardiovascular G-protein-coupled receptors induce morphological cardiomyopathic changes in immunized rabbits.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Direct evidence for a beta 1-adrenergic receptor-directed autoimmune attack as a cause of idiopathic dilated cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Beta 1-adrenergic receptor-directed autoimmunity as a cause of dilated cardiomyopathy in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Therapeutic use of muscarinic acetylcholine receptor peptide to prevent mice chagasic cardiac dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Long-term benefits of immunoadsorption in β(1)-adrenoceptor autoantibody-positive transplant candidates with dilated cardiomyopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Immunoadsorption therapy for dilated cardiomyopathy and pulmonary arterial hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Removal of autoantibodies in dilated cardiomyopathy by immunoadsorption

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Complete elimination of cardiodepressant IgG3 autoantibodies by immunoadsorption in patients with severe heart failure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Effects of immunoadsorption and subsequent immunoglobulin G substitution on cardiopulmonary exercise capacity in patients with dilated cardiomyopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Ig apheresis for the treatment of severe DCM patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Immunoglobulin adsorption in patients with idiopathic dilated cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Decreased oxidative stress in patients with idiopathic dilated cardiomyopathy one year after immunoglobulin adsorption

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Reduced oxidative stress in parallel to improved cardiac performance one year after selective removal of anti-beta 1-adrenoreceptor autoantibodies in patients with idiopathic dilated cardiomyopathy: data of a preliminary study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Economic evaluation and survival analysis of immunoglobulin adsorption in patients with idiopathic dilated cardiomyopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Anti-beta1-adrenergic receptor autoantibodies in patients with chronic Chagas heart disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Distinct patterns of autoantibodies against G-protein-coupled receptors in Chagas' cardiomyopathy and megacolon. Their potential impact for early risk assessment in asymptomatic Chagas' patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Potential relevance of alpha(1)-adrenergic receptor autoantibodies in refractory hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Effects of protein A immunoadsorption in patients with chronic dilated cardiomyopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Specific immunoadsorption therapy using a tryptophan column in patients with refractory heart failure due to dilated cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Aptamer binding and neutralization of β1-adrenoceptor autoantibodies: basics and a vision of its future in cardiomyopathy treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Autoantibodies activating human beta1-adrenergic receptors are associated with reduced cardiac function in chronic heart failure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Anti-β-adrenoceptors autoimmunity causing 'idiopathic' arrhythmias and cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Pro-apoptotic effect of anti-β1-adrenergic receptor antibodies in periodontitis patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Antiadrenergic and muscarinic receptor antibodies in Chagas' cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Agonistic autoantibodies to the α(1) -adrenergic receptor and the β(2) -adrenergic receptor in Alzheimer's and vascular dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Autoimmunity against the β2 adrenergic receptor and muscarinic-2 receptor in complex regional pain syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Antibodies to the α1-adrenergic receptor cause vascular impairments in rat brain as demonstrated by magnetic resonance angiography

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Are Agonistic Autoantibodies against G-Protein Coupled Receptors Involved in the Development of Long-Term Side Effects of Tumor Chemotherapy?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Patients with preeclampsia develop agonistic autoantibodies against the angiotensin AT1 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

AT1 receptor agonistic antibodies from preeclamptic patients stimulate NADPH oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Maternal autoantibodies from preeclamptic patients activate angiotensin receptors on human mesangial cells and induce interleukin-6 and plasminogen activator inhibitor-1 secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Agonistic AT1 receptor autoantibodies and monocyte stimulation in hypertensive patients*1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Angiotensin II type 1-receptor activating antibodies in renal-allograft rejection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Anti-M2 muscarinic receptor autoantibodies and idiopathic dilated cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Autoantibodies against the beta- and muscarinic receptors in cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Functional epitope of muscarinic type 3 receptor which interacts with autoantibodies from Sjogren's syndrome patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Autoantibodies in Sjögren's syndrome patients acutely inhibit muscarinic receptor function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Autoantibodies against muscarinic type 3 receptor in Sjögren's syndrome inhibit aquaporin 5 trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Autoantibodies to muscarinic acetylcholine receptors found in patients with primary biliary cirrhosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Agonistic autoantibodies as vasodilators in orthostatic hypotension: a new mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Autoantibodies against muscarinic receptors in breast cancer: their role in tumor angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Immunoglobulin G from breast cancer patients in stage I stimulates muscarinic acetylcholine receptors in MCF7 cells and induces proliferation. Participation of nitric oxide synthase-derived nitric oxide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Muscarinic receptors autoantibodies purified from mammary adenocarcinoma-bearing mice sera stimulate tumor progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Involvement of functional autoantibodies against vascular receptors in systemic sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0425-9

Immunoadsorption in idiopathic dilated cardiomyopathy, a 3-year follow-up

21 January 2018

1 reference

12 December 2020

Specific removal of beta1-adrenergic autoantibodies from patients with idiopathic dilated cardiomyopathy

1 reference

12 December 2020

The first aptamer-apheresis column specifically for clearing blood of β1-receptor autoantibodies

1 reference

12 December 2020

Anti-beta 1-adrenoceptor autoantibodies with chronotropic activity from the serum of patients with dilated cardiomyopathy: mapping of epitopes in the first and second extracellular loops

1 reference

12 December 2020

Interaction of human chagasic IgG with the second extracellular loop of the human heart muscarinic acetylcholine receptor: functional and pathological implications

1 reference

12 December 2020

From agonist to antagonist: Fab fragments of an agonist-like monoclonal anti-beta(2)-adrenoceptor antibody behave as antagonists

1 reference

12 December 2020

Antibodies to beta 1 and beta 2 adrenoreceptors in Chagas' disease

1 reference

12 December 2020

Alpha 1-adrenergic receptor antibodies in patients with primary hypertension

1 reference

12 December 2020

Sera from patients with type 2 diabetes contain agonistic autoantibodies against G protein-coupled receptors

1 reference

12 December 2020

Autoantibodies to β-adrenergic receptors with antiadrenergic activity from patients with allergic asthma

1 reference

12 December 2020

Administration of the cyclic peptide COR-1 in humans (phase I study): ex vivo measurements of anti-β1-adrenergic receptor antibody neutralization and of immune parameters

1 reference

12 December 2020

Detection of anti-β1-AR autoantibodies in heart failure by a cell-based competition ELISA

1 reference

12 December 2020

Protective effect of bisoprolol on beta-1 adrenoceptor peptide-induced autoimmune myocardial damage in rabbits

1 reference

12 December 2020

Functional autoimmune epitope on alpha 1-adrenergic receptors in patients with malignant hypertension

1 reference

12 December 2020

Autoantibodies against the beta-adrenergic receptor in human myocarditis and dilated cardiomyopathy: beta-adrenergic agonism without desensitization

1 reference

12 December 2020

Transfer of rabbit autoimmune cardiomyopathy into severe combined immunodeficiency mice

1 reference

12 December 2020

Autoantibodies against the serotoninergic 5-HT4 receptor and congenital heart block: a reassessment

1 reference

12 December 2020

Autoantibodies against the second extracellular loop of beta1-adrenergic receptors predict ventricular tachycardia and sudden death in patients with idiopathic dilated cardiomyopathy

1 reference

12 December 2020

Reduction of morbidity by immunoadsorption therapy in patients with dilated cardiomyopathy

1 reference

12 December 2020

Effects of the serum gamma globulin fraction of patients with allergic asthma and dilated cardiomyopathy on chronotropic beta adrenoceptor function in cultured neonatal rat heart myocytes

1 reference

12 December 2020

Induction of cardiomyopathy in severe combined immunodeficiency mice by transfer of lymphocytes from patients with idiopathic dilated cardiomyopathy

1 reference

12 December 2020

Agonistic antibody to the alpha1-adrenergic receptor mobilizes intracellular calcium and induces phosphorylation of a cardiac 15-kDa protein

1 reference

12 December 2020

Dilated cardiomyopathy defines serum autoantibodies against G-protein-coupled cardiovascular receptors

1 reference

12 December 2020

Beta 1-adrenergic receptor autoantibodies mediate dilated cardiomyopathy by agonistically inducing cardiomyocyte apoptosis

1 reference

12 December 2020

Immunochemical and functional characterization of an agonist-like monoclonal antibody against the M2 acetylcholine receptor

1 reference

12 December 2020

Autoantibodies against the angiotensin receptor (AT1) in patients with hypertension

1 reference

12 December 2020

Distinct patterns of autoantibodies against G-protein-coupled receptors in Chagas' cardiomyopathy and megacolon: their potential impact for early risk assessment in asymptomatic Chagas' patients

1 reference

12 December 2020

Influence of anti-beta-receptor antibodies on cardiac adenylate cyclase in patients with idiopathic dilated cardiomyopathy

1 reference

12 December 2020

Role of anti-β1 adrenergic antibodies from patients with periodontitis in cardiac dysfunction

1 reference

12 December 2020

Autoantibodies against M2 muscarinic receptors in patients with cardiomyopathy display non-desensitized agonist-like effects

1 reference

12 December 2020

Toxicological evaluation of oligonucleotide therapeutics

1 reference

12 December 2020

Modulation of beta1-adrenoceptor activity by domain-specific antibodies and heart failure-associated autoantibodies

1 reference

12 December 2020

Activation of cyclic AMP-dependent protein kinase in cardiomyocytes by anti-beta 1-adrenoceptor autoantibodies from patients with idiopathic dilated cardiomyopathy

1 reference

12 December 2020

Autoantibodies against G-protein-coupled receptors modulate heart mast cells

1 reference

12 December 2020

A novel fluorescence method for the rapid detection of functional beta1-adrenergic receptor autoantibodies in heart failure

1 reference

12 December 2020

A circulating IgG in Chagas' disease which binds to beta-adrenoceptors of myocardium and modulates their activity

1 reference

12 December 2020

Immunoadsorption in dilated cardiomyopathy: long-term reduction of cardiodepressant antibodies

1 reference

12 December 2020

Agonistic effects of anti-peptide antibodies and autoantibodies directed against adrenergic and cholinergic receptors: absence of desensitization

1 reference

12 December 2020

Identification of antibodies with muscarinic cholinergic activity in human Chagas' disease: pathological implications

1 reference

12 December 2020

Fc(gamma) receptors IIa on cardiomyocytes and their potential functional relevance in dilated cardiomyopathy

1 reference

12 December 2020

AT(1) receptor agonistic antibodies from preeclamptic patients cause vascular cells to express tissue factor

1 reference

12 December 2020

Short-term hemodynamic effects of immunoadsorption in dilated cardiomyopathy

1 reference

12 December 2020

High prevalence of antibodies against beta 1- and beta 2-adrenoceptors in patients with primary electrical cardiac abnormalities

1 reference

12 December 2020

Anti-SSA/Ro52 autoantibodies blocking the cardiac 5-HT4 serotoninergic receptor could explain neonatal lupus congenital heart block

1 reference

12 December 2020

10.1007/S00281-014-0425-9

Identifiers

DOI

1 reference

PubMed ID

24777744

Dimensions Publication ID

31 August 2017

0 references

1 reference

PubMed ID

24777744