(Q38210525)

31 August 2017

Chromatin modifications remodel cardiac gene expression (English)

1 reference

31 August 2017

Samuel T Keating

2

0 references

Assam El-osta

object named as

Assam El-Osta

series ordinal

4

0 references

author name string

Prabhu Mathiyalagan

series ordinal

1

1 reference

PubMed ID

24812277

31 August 2017

Xiao-Jun Du

series ordinal

3

1 reference

31 August 2017

8 May 2014

1 reference

31 August 2017

Cardiovascular Research

1 reference

31 August 2017

103

1 reference

31 August 2017

1

1 reference

31 August 2017

7-16

1 reference

Transcriptional profiling of the heart reveals chamber-specific gene expression patterns

31 August 2017

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Chamber-specific cardiac expression of Tbx5 and heart defects in Holt-Oram syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Transcriptional regulation of vertebrate cardiac morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Cardiac transcription factor Csx/Nkx2-5: Its role in cardiac development and diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

21 January 2018

Cardiac regeneration.

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Co-occupancy by multiple cardiac transcription factors identifies transcriptional enhancers active in heart.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

The transcription of chromatin templates

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Translating the Histone Code

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Loss of H3K4 methylation destabilizes gene expression patterns and physiological functions in adult murine cardiomyocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Epigenetic repression of cardiac progenitor gene expression by Ezh2 is required for postnatal cardiac homeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

De novo mutations in histone-modifying genes in congenital heart disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Chromatin regulation by Brg1 underlies heart muscle development and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Long noncoding RNAs in cardiac development and pathophysiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Interplay of chromatin modifications and non-coding RNAs in the heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

The primary microRNA-208b interacts with Polycomb-group protein, Ezh2, to regulate gene expression in the heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Braveheart, a long noncoding RNA required for cardiovascular lineage commitment

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

The tissue-specific lncRNA Fendrr is an essential regulator of heart and body wall development in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Molecular pathways underlying cardiac remodeling during pathophysiological stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Cardiac remodeling--concepts and clinical implications: a consensus paper from an international forum on cardiac remodeling. Behalf of an International Forum on Cardiac Remodeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Cardiac hypertrophy: the good, the bad, and the ugly

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Regulation of cardiac hypertrophy by intracellular signalling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Beta-adrenergic receptors in heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Altered Na/Ca exchange activity in cardiac hypertrophy and heart failure: a new target for therapy?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Chromatin remodeling in cardiovascular development and physiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Therapeutic potential for HDAC inhibitors in the heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Control of cardiac growth by histone acetylation/deacetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Distinct epigenomic features in end-stage failing human hearts

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Genome-wide histone methylation profile for heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

MEF2: a calcium-dependent regulator of cell division, differentiation and death

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Signal-dependent nuclear export of a histone deacetylase regulates muscle differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

p300 Functions as a coactivator of transcription factor GATA-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Chromatin remodelling: the industrial revolution of DNA around histones

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

The biology of chromatin remodeling complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Histones: annotating chromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Chromatin remodelling complex dosage modulates transcription factor function in heart development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Factors controlling cardiac myosin-isoform shift during hypertrophy and heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Maintenance of adult cardiac function requires the chromatin factor Asxl2

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Initiation of transcription on nucleosomal templates

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Transcriptional regulation patterns revealed by high resolution chromatin immunoprecipitation during cardiac hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

The cardiac transcription network modulated by Gata4, Mef2a, Nkx2.5, Srf, histone modifications, and microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Genome-wide analysis of histone marks identifying an epigenetic signature of promoters and enhancers underlying cardiac hypertrophy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Cardiac ventricular chambers are epigenetically distinguishable

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

The transcriptional co-activators CREB-binding protein (CBP) and p300 play a critical role in cardiac hypertrophy that is dependent on their histone acetyltransferase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Cardiac p300 Is Involved in Myocyte Growth with Decompensated Heart Failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Control of cardiac-specific transcription by p300 through myocyte enhancer factor-2D

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Molecular mechanisms of myogenic coactivation by p300: direct interaction with the activation domain of MyoD and with the MADS box of MEF2C

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Histone deacetylases facilitate sodium/calcium exchanger up-regulation in adult cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Cyclin-dependent kinase-9 is a component of the p300/GATA4 complex required for phenylephrine-induced hypertrophy in cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

A natural p300-specific histone acetyltransferase inhibitor, curcumin, in addition to angiotensin-converting enzyme inhibitor, exerts beneficial effects on left ventricular systolic function after myocardial infarction in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Small-molecule therapies for cardiac hypertrophy: moving beneath the cell surface

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Inhibition of histone deacetylation blocks cardiac hypertrophy induced by angiotensin II infusion and aortic banding

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Endothelin-stimulated human B-type natriuretic peptide gene expression is mediated by Yin Yang 1 in association with histone deacetylase 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Lysine acetylation targets protein complexes and co-regulates major cellular functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Histone deacetylases (HDACs): characterization of the classical HDAC family

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Histone deacetylase inhibitors: Potential in cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Molecular evolution of the histone deacetylase family: functional implications of phylogenetic analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Histone deacetylase inhibitors: overview and perspectives

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Roles and targets of class I and IIa histone deacetylases in cardiac hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Histone deacetylases 5 and 9 govern responsiveness of the heart to a subset of stress signals and play redundant roles in heart development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Class II histone deacetylases act as signal-responsive repressors of cardiac hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Dose-dependent blockade to cardiomyocyte hypertrophy by histone deacetylase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Histone deacetylase (HDAC) inhibitors attenuate cardiac hypertrophy by suppressing autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Krüppel-like factor 4 mediates histone deacetylase inhibitor-induced prevention of cardiac hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Hdac2 regulates the cardiac hypertrophic response by modulating Gsk3 beta activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Activation of histone deacetylase 2 by inducible heat shock protein 70 in cardiac hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Histone deacetylase-3 activation promotes tumor necrosis factor-alpha (TNF-alpha) expression in cardiomyocytes during lipopolysaccharide stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

HDAC4 controls histone methylation in response to elevated cardiac load

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Histone deacetylase inhibition reduces myocardial ischemia-reperfusion injury in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

YY1 protects cardiac myocytes from pathologic hypertrophy by interacting with HDAC5

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Deacetylase inhibition promotes the generation and function of regulatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

A phase I study of intravenous LBH589, a novel cinnamic hydroxamic acid analogue histone deacetylase inhibitor, in patients with refractory hematologic malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Tolerability, pharmacodynamics, and pharmacokinetics studies of depsipeptide (romidepsin) in patients with acute myelogenous leukemia or advanced myelodysplastic syndromes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Suppression of class I and II histone deacetylases blunts pressure-overload cardiac hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

The many roles of histone deacetylases in development and physiology: implications for disease and therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Histone deacetylases 1 and 2 redundantly regulate cardiac morphogenesis, growth, and contractility

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

A phase 1 pharmacokinetic and pharmacodynamic study of the histone deacetylase inhibitor belinostat in patients with advanced solid tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Complex role of histone deacetylase inhibitors in the treatment of non-small-cell lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

HDAC inhibition in rheumatoid arthritis and juvenile idiopathic arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Protein acetylation in the cardiorenal axis: the promise of histone deacetylase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

New and emerging HDAC inhibitors for cancer treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Histone deacetylase inhibition blunts ischemia/reperfusion injury by inducing cardiomyocyte autophagy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

The histone trimethyllysine demethylase JMJD2A promotes cardiac hypertrophy in response to hypertrophic stimuli in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Dynamic and coordinated epigenetic regulation of developmental transitions in the cardiac lineage

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

A temporal chromatin signature in human embryonic stem cells identifies regulators of cardiac development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Crystal Structure of Cardiac-specific Histone Methyltransferase SmyD1 Reveals Unusual Active Site Architecture

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Caveolin induces cardioprotection through epigenetic regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Conditional ablation of Ezh2 in murine hearts reveals its essential roles in endocardial cushion formation, cardiomyocyte proliferation and survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

DUX4, a candidate gene of facioscapulohumeral muscular dystrophy, encodes a transcriptional activator of PITX1

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Epigenetic regulation of endothelial lineage committed genes in pro-angiogenic hematopoietic and endothelial progenitor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Hallmarks of ion channel gene expression in end-stage heart failure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

The homeodomain transcription factor Irx5 establishes the mouse cardiac ventricular repolarization gradient

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Cardiac deletion of Smyd2 is dispensable for mouse heart development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

DOT1L regulates dystrophin expression and is critical for cardiac function

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Histone demethylation mediated by the nuclear amine oxidase homolog LSD1

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

An FHL1-containing complex within the cardiomyocyte sarcomere mediates hypertrophic biomechanical stress responses in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

The Polycomb complex PRC2 and its mark in life

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Polycomb repressive complex 2 regulates normal development of the mouse heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

A unique chromatin signature uncovers early developmental enhancers in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Histone H3 acetylation and H3 K4 methylation define distinct chromatin regions permissive for transgene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Distinct localization of histone H3 acetylation and H3-K4 methylation to the transcription start sites in the human genome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Global assessment of combinatorial post-translational modification of core histones in yeast using contemporary mass spectrometry. LYS4 trimethylation correlates with degree of acetylation on the same H3 tail.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Methylation of histone H3 mediates the association of the NuA3 histone acetyltransferase with chromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Profile of histone lysine methylation across transcribed mammalian chromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Transcription regulation by histone methylation: interplay between different covalent modifications of the core histone tails

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Association of class II histone deacetylases with heterochromatin protein 1: potential role for histone methylation in control of muscle differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Suv39h-mediated histone H3 lysine 9 methylation directs DNA methylation to major satellite repeats at pericentric heterochromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Cardiac alpha- and beta-myosin heavy chain genes are organized in tandem

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Impact of beta-myosin heavy chain isoform expression on cross-bridge cycling kinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Impact of beta-myosin heavy chain expression on cardiac function during stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Changes in gene expression in the intact human heart. Downregulation of alpha-myosin heavy chain in hypertrophied, failing ventricular myocardium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Myosin heavy chain isoform expression in the failing and nonfailing human heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Role of antisense RNA in coordinating cardiac myosin heavy chain gene switching

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Regulation of antisense RNA expression during cardiac MHC gene switching in response to pressure overload

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

A conserved GATA motif in a tissue-specific DNase I hypersensitive site of the cardiac alpha-myosin heavy chain gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Chromatin remodelling of the cardiac beta-myosin heavy chain gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

The polycomb group protein EZH2 is involved in progression of prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Selective killing of mixed lineage leukemia cells by a potent small-molecule DOT1L inhibitor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Molecular pathways: protein methyltransferases in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Targeting epigenetic regulators for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Cardiac genes show contextual SWI/SNF interactions with distinguishable gene activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVU122

Curcumin prevents and reverses murine cardiac hypertrophy

21 January 2018

1 reference

12 January 2024

https://opencitations.net/index/api/v1/citations/10.1172/JCI32865

Identifiers

DOI

10.1093/CVR/CVU122

1 reference

31 August 2017

1 reference

PubMed ID

24812277