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The role of ghrelin in neuroprotection after ischemic brain injury.
scientific article published on 19 March 2013
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Europe PubMed Central
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4061836
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21 March 2020
title
The role of ghrelin in neuroprotection after ischemic brain injury
(English)
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Europe PubMed Central
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4061836
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24961317%20AND%20SRC:MED&resulttype=core&format=json
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21 March 2020
author
Sarah J. Spencer
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1
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Europe PubMed Central
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4061836
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21 March 2020
Zane B. Andrews
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3
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Europe PubMed Central
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4061836
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21 March 2020
author name string
Alyson A Miller
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2
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21 March 2020
publication date
19 March 2013
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21 March 2020
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Brain Sciences
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Europe PubMed Central
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4061836
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21 March 2020
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3
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Europe PubMed Central
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4061836
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21 March 2020
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1
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Europe PubMed Central
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21 March 2020
page(s)
344-359
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21 March 2020
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Creative Commons Attribution 4.0 International
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19 March 2013
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Ghrelin protects against cobalt chloride-induced hypoxic injury in cardiac H9c2 cells by inhibiting oxidative stress and inducing autophagy
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Acute effect of Ghrelin on ischemia/reperfusion injury in the rat spinal cord
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Ghrelin regulates the hypothalamic-pituitary-adrenal axis and restricts anxiety after acute stress.
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Apo-ghrelin receptor forms heteromers with DRD2 in hypothalamic neurons and is essential for anorexigenic effects of DRD2 agonism
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Ghrelin attenuates brain injury after traumatic brain injury and uncontrolled hemorrhagic shock in rats.
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Mutually opposite signal modulation by hypothalamic heterodimerization of ghrelin and melanocortin-3 receptors
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Death and survival of neuronal and astrocytic cells in ischemic brain injury: a role of autophagy
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Central mechanisms involved in the orexigenic actions of ghrelin
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Metabolic status regulates ghrelin function on energy homeostasis
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The extra-hypothalamic actions of ghrelin on neuronal function.
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Ghrelin ameliorates cognitive dysfunction and neurodegeneration in intrahippocampal amyloid-β1-42 oligomer-injected mice
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Ghrelin promotes and protects nigrostriatal dopamine function via a UCP2-dependent mitochondrial mechanism
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Neuroprotective effect of ghrelin in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease by blocking microglial activation
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Neuroprotective effect of ghrelin is associated with decreased expression of prostate apoptosis response-4.
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The orexigenic hormone ghrelin defends against depressive symptoms of chronic stress
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Phosphatidylinositol-3-kinase/Akt/glycogen synthase kinase-3 beta and ERK1/2 pathways mediate protective effects of acylated and unacylated ghrelin against oxygen-glucose deprivation-induced apoptosis in primary rat cortical neuronal cells
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Ghrelin octanoylation mediated by an orphan lipid transferase
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Identification of the acyltransferase that octanoylates ghrelin, an appetite-stimulating peptide hormone
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Ghrelin and the short- and long-term regulation of appetite and body weight
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Ghrelin controls hippocampal spine synapse density and memory performance
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Ghrelin induces feeding in the mesolimbic reward pathway between the ventral tegmental area and the nucleus accumbens
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Ghrelin, the same peptide for different functions: player or bystander?
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6 September 2017
Ghrelin: structure and function
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Neuroendocrine and peripheral activities of ghrelin: implications in metabolism and obesity
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A structural view of mitochondria-mediated apoptosis
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Evidence for the involvement of Par-4 in ischemic neuron cell death
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A role for ghrelin in the central regulation of feeding
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Ghrelin induces adiposity in rodents
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Ghrelin is a growth-hormone-releasing acylated peptide from stomach
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28 September 2017
Vagal stimulation modulates inflammation through a ghrelin mediated mechanism in traumatic brain injury
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UCP2 mediates ghrelin's action on NPY/AgRP neurons by lowering free radicals
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Ghrelin reduces injury of hippocampal neurons in a rat model of cerebral ischemia/reperfusion.
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Protective effects of ghrelin on ischemia/reperfusion injury in the isolated rat heart
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Early ghrelin treatment attenuates disruption of the blood brain barrier and apoptosis after traumatic brain injury through a UCP-2 mechanism
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Ghrelin suppresses tunicamycin- or thapsigargin-triggered endoplasmic reticulum stress-mediated apoptosis in primary cultured rat cortical neuronal cells
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Expression of the ghrelin and neurotensin systems is altered in the temporal lobe of Alzheimer's disease patients.
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Diet-induced obesity causes ghrelin resistance in arcuate NPY/AgRP neurons
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31 August 2018
Ghrelin modulates insulin sensitivity and tau phosphorylation in high glucose-induced hippocampal neurons
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31 August 2018
The anti-inflammatory and neuroprotective effects of ghrelin in subarachnoid hemorrhage-induced oxidative brain damage in rats.
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31 August 2018
Protective role of autophagy in neonatal hypoxia-ischemia induced brain injury
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31 August 2018
Ghrelin antagonizes MPTP-induced neurotoxicity to the dopaminergic neurons in mouse substantia nigra
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31 August 2018
Ghrelin improves burn-induced multiple organ injury by depressing neutrophil infiltration and the release of pro-inflammatory cytokines.
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31 August 2018
Ghrelin protects cortical neuron against focal ischemia/reperfusion in rats.
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31 August 2018
Constant intravenous ghrelin infusion in healthy young men: clinical pharmacokinetics and metabolic effects.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061836
retrieved
31 August 2018
Ghrelin inhibits apoptosis in hypothalamic neuronal cells during oxygen-glucose deprivation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061836
retrieved
31 August 2018
Plasma levels of neuropeptides in Alzheimer's disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061836
retrieved
31 August 2018
Effect of aging on the response of ghrelin to acute weight loss
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061836
retrieved
31 August 2018
Ghrelin improves tissue perfusion in severe sepsis via downregulation of endothelin-1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061836
retrieved
31 August 2018
Regulation of growth hormone secretagogue receptor gene expression in the arcuate nuclei of the rat by leptin and ghrelin.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061836
retrieved
31 August 2018
Effect of ghrelin and synthetic growth hormone secretagogues in normal and ischemic rat heart
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061836
retrieved
31 August 2018
Low Plasma Ghrelin Is Associated With Insulin Resistance, Hypertension, and the Prevalence of Type 2 Diabetes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061836
retrieved
31 August 2018
Ghrelin Arg51Gln mutation is a risk factor for Type 2 diabetes and hypertension in a random sample of middle-aged subjects
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061836
retrieved
31 August 2018
The endocrine response to ghrelin as a function of gender in humans in young and elderly subjects
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061836
retrieved
31 August 2018
The distribution and mechanism of action of ghrelin in the CNS demonstrates a novel hypothalamic circuit regulating energy homeostasis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061836
retrieved
31 August 2018
Ghrelin and des-acyl ghrelin inhibit cell death in cardiomyocytes and endothelial cells through ERK1/2 and PI 3-kinase/AKT.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061836
retrieved
31 August 2018
Extent and direction of ghrelin transport across the blood-brain barrier is determined by its unique primary structure
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061836
retrieved
31 August 2018
Circulating ghrelin levels are decreased in human obesity.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061836
retrieved
31 August 2018
Growth Hormone-Releasing Peptide Hexarelin Reduces Neonatal Brain Injury and Alters Akt/Glycogen Synthase Kinase-3β Phosphorylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.3390%2FBRAINSCI3010344
retrieved
21 January 2018
Protective effect of microglial conditioning medium on neuronal damage induced by glutamate
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24961317
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Ghrelin suppresses inflammation and neuronal nitric oxide synthase in focal cerebral ischemia via the vagus nerve
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24961317
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Ghrelin protects musculocutaneous tissue from ischemic necrosis by improving microvascular perfusion
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24961317
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.3390/BRAINSCI3010344
1 reference
stated in
Europe PubMed Central
PMCID
4061836
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24961317%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 March 2020
PMCID
4061836
1 reference
stated in
Europe PubMed Central
PMCID
4061836
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24961317%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 March 2020
PubMed ID
24961317
1 reference
stated in
Europe PubMed Central
PMCID
4061836
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24961317%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 March 2020
ResearchGate publication ID
263011577
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