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Heterogeneity and plasticity of epidermal stem cells (English)

1 reference

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21 March 2020

8 references

3 April 2019

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15 September 2022

1 reference

11 October 2019

1 reference

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1 reference

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1 reference

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1 reference

3

1 reference

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21 March 2020

author name string

Troels Schepeler

series ordinal

1

1 reference

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21 March 2020

Mahalia E Page

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2

1 reference

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English

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publication date

1 July 2014

9 references

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21 October 2019

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21 March 2020

20 December 2020

15 September 2022

9

1 reference

inferred from page(s)

9 references

3 April 2019

30 June 2019

20 June 2019

11 October 2019

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21 October 2019

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141

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issue

13

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21 March 2020

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2559-2567

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Keratin 79 identifies a novel population of migratory epithelial cells that initiates hair canal morphogenesis and regeneration

6 September 2017

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6 September 2017

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Differentiated Troy+ chief cells act as reserve stem cells to generate all lineages of the stomach epithelium

6 September 2017

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Regenerating the skin: a task for the heterogeneous stem cell pool and surrounding niche

6 September 2017

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Unravelling stem cell dynamics by lineage tracing

6 September 2017

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c-MYC-induced sebaceous gland differentiation is controlled by an androgen receptor/p53 axis

6 September 2017

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Epithelial stem cells and implications for wound repair

6 September 2017

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Elevated epidermal thymic stromal lymphopoietin levels establish an antitumor environment in the skin

6 September 2017

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The roles of receptor tyrosine kinases and their ligands in the wound repair process

6 September 2017

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FGF receptors 1 and 2 are key regulators of keratinocyte migration in vitro and in wounded skin

6 September 2017

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Live imaging of stem cell and progeny behaviour in physiological hair-follicle regeneration

6 September 2017

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Stress-induced production of chemokines by hair follicles regulates the trafficking of dendritic cells in skin.

6 September 2017

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Epithelial stem cells, wound healing and cancer

6 September 2017

1 reference

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Basal cell carcinoma - molecular biology and potential new therapies

6 September 2017

1 reference

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6 September 2017

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Paracrine TGF-β signaling counterbalances BMP-mediated repression in hair follicle stem cell activation

6 September 2017

1 reference

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MicroRNA-21 is an important downstream component of BMP signalling in epidermal keratinocytes

6 September 2017

1 reference

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Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1

6 September 2017

1 reference

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TCF/Lef1 activity controls establishment of diverse stem and progenitor cell compartments in mouse epidermis

6 September 2017

1 reference

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Defining the origins of Ras/p53-mediated squamous cell carcinoma

6 September 2017

1 reference

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Identifying the cellular origin of squamous skin tumors

6 September 2017

1 reference

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Wounding mobilizes hair follicle stem cells to form tumors

6 September 2017

1 reference

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Wounding enhances epidermal tumorigenesis by recruiting hair follicle keratinocytes.

6 September 2017

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Boundary formation and maintenance in tissue development

6 September 2017

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Gastric epithelial stem cells

6 September 2017

1 reference

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Identification of epidermal progenitors for the Merkel cell lineage

6 September 2017

1 reference

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Fibroblast growth factor receptors 1 and 2 in keratinocytes control the epidermal barrier and cutaneous homeostasis

6 September 2017

1 reference

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Expression of the orphan protein Plet-1 during trichilemmal differentiation of anagen hair follicles

6 September 2017

1 reference

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Epidermal progenitors give rise to Merkel cells during embryonic development and adult homeostasis

6 September 2017

1 reference

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Necl2 regulates epidermal adhesion and wound repair

6 September 2017

1 reference

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Mammalian Merkel cells are descended from the epidermal lineage

6 September 2017

1 reference

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Sox2-positive dermal papilla cells specify hair follicle type in mammalian epidermis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

Merkel cells are essential for light-touch responses

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

A two-step mechanism for stem cell activation during hair regeneration

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

Basal cell carcinomas: attack of the hedgehog

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

Hair follicle stem cells are specified and function in early skin morphogenesis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

Wound repair and regeneration

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

More than one way to skin . .

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

A distinct population of clonogenic and multipotent murine follicular keratinocytes residing in the upper isthmus.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

Cyclic dermal BMP signalling regulates stem cell activation during hair regeneration

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

Complex hair cycle domain patterns and regenerative hair waves in living rodents

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

Epidermal terminal differentiation depends on B lymphocyte-induced maturation protein-1.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

Wnt-dependent de novo hair follicle regeneration in adult mouse skin after wounding

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

Hyperactive Ras in developmental disorders and cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

Canonical notch signaling functions as a commitment switch in the epidermal lineage

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

Jagged 1 is a beta-catenin target gene required for ectopic hair follicle formation in adult epidermis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

Blimp1 defines a progenitor population that governs cellular input to the sebaceous gland

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

The cell-surface marker MTS24 identifies a novel population of follicular keratinocytes with characteristics of progenitor cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

Characterization and isolation of stem cell-enriched human hair follicle bulge cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

Stem cells in the hair follicle bulge contribute to wound repair but not to homeostasis of the epidermis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

Long-term renewal of hair follicles from clonogenic multipotent stem cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

Notch1 is essential for postnatal hair follicle development and homeostasis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

Molecular principles of hair follicle induction and morphogenesis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

gamma-secretase functions through Notch signaling to maintain skin appendages but is not required for their patterning or initial morphogenesis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

Capturing and profiling adult hair follicle stem cells.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

Defining the epithelial stem cell niche in skin

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

Hair follicle stem cells.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

Notch1 functions as a tumor suppressor in mouse skin

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

Beta-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

beta-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

Multiple classes of stem cells in cutaneous epithelium: a lineage analysis of adult mouse skin

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

De Novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

Sonic hedgehog signaling is essential for hair development

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

The C8/144B monoclonal antibody recognizes cytokeratin 15 and defines the location of human hair follicle stem cells.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

Identification and isolation of candidate human keratinocyte stem cells based on cell surface phenotype

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

Label-retaining cells reside in the bulge area of pilosebaceous unit: implications for follicular stem cells, hair cycle, and skin carcinogenesis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

Serial cultivation of strains of human epidermal keratinocytes: the formation of keratinizing colonies from single cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

Cleavage of E-cadherin by ADAM10 mediates epithelial cell sorting downstream of EphB signalling

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

c-Met is essential for wound healing in the skin

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

Epidermal stem cell diversity and quiescence

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

Lrig1 expression defines a distinct multipotent stem cell population in mammalian epidermis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

The interfollicular epidermis of adult mouse tail comprises two distinct cell lineages that are differentially regulated by Wnt, Edaradd, and Lrig1.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

The epidermis comprises autonomous compartments maintained by distinct stem cell populations

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

The touch dome defines an epidermal niche specialized for mechanosensory signaling

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

Identification of stem cells that maintain and regenerate lingual keratinized epithelial cells

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

Adult interfollicular tumour-initiating cells are reprogrammed into an embryonic hair follicle progenitor-like fate during basal cell carcinoma initiation

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

Multipotent and unipotent progenitors contribute to prostate postnatal development

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

Age-associated inflammation inhibits epidermal stem cell function

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

Adult murine prostate basal and luminal cells are self-sustained lineages that can both serve as targets for prostate cancer initiation

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

The circadian molecular clock creates epidermal stem cell heterogeneity.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

Nerve-derived sonic hedgehog defines a niche for hair follicle stem cells capable of becoming epidermal stem cells

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

The ordered architecture of murine ear epidermis is maintained by progenitor cells with random fate.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

Identification of the cell lineage at the origin of basal cell carcinoma

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

Enrichment for living murine keratinocytes from the hair follicle bulge with the cell surface marker CD34.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

The spatial relationship between stem cells and their progeny in the basal layer of human epidermis: a new view based on whole-mount labelling and lineage analysis

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

A zone of non-proliferating cells at a lineage restriction boundary in Drosophila.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

Keratin expression in basal cell carcinomas

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

Differential response of epithelial stem cell populations in hair follicles to TGF-β signaling.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

Distinct contribution of stem and progenitor cells to epidermal maintenance

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

Ephrins negatively regulate cell proliferation in the epidermis and hair follicle

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

Lgr5 marks cycling, yet long-lived, hair follicle stem cells.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

An extended epidermal response heals cutaneous wounds in the absence of a hair follicle stem cell contribution.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

A single type of progenitor cell maintains normal epidermis.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

Distinct stem cell populations regenerate the follicle and interfollicular epidermis

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

Endogenous oncogenic K-ras(G12D) stimulates proliferation and widespread neoplastic and developmental defects.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

Keratin 15 promoter targets putative epithelial stem cells in the hair follicle bulge.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

Manipulation of stem cell proliferation and lineage commitment: visualisation of label-retaining cells in wholemounts of mouse epidermis

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067958

Involvement of follicular stem cells in forming not only the follicle but also the epidermis

31 August 2018

1 reference

12 December 2020

Morphogenesis and renewal of hair follicles from adult multipotent stem cells

1 reference

12 December 2020

The incorporation of tritiated uridine in hair germ and dermal papilla during dormancy (telogen) and activation (early anagen)

1 reference

12 December 2020

Permanent coverage of large burn wounds with autologous cultured human epithelium

1 reference

12 December 2020

Lgr6 Marks Stem Cells in the Hair Follicle That Generate All Cell Lineages of the Skin

1 reference

12 December 2020

Distinct stem cells contribute to mammary gland development and maintenance

1 reference

12 December 2020

Location of stem cells of human hair follicles by clonal analysis

1 reference

12 December 2020

Stem cell patterning and fate in human epidermis

1 reference

12 December 2020

Epidermal stem cells arise from the hair follicle after wounding

1 reference

12 December 2020

Stem cell dynamics in sebaceous gland morphogenesis in mouse skin

1 reference

12 December 2020

Identifiers

DOI

10.1242/DEV.104588

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24961797%20AND%20SRC:MED&resulttype=core&format=json

release_5ket4wel4zghbeama7t3v65wem

21 March 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/5ket4wel4zghbeama7t3v65wem

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24961797%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

PubMed publication ID

24961797

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24961797%20AND%20SRC:MED&resulttype=core&format=json