(Q38227398)

31 August 2017

title

β-catenin as a regulator and therapeutic target for asthmatic airway remodeling (English)

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31 August 2017

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Kuldeep Kumawat

1

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31 August 2017

Tim Koopmans

series ordinal

2

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31 August 2017

Reinoud Gosens

series ordinal

3

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31 August 2017

language of work or name

English

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publication date

8 July 2014

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Expert Opinion on Therapeutic Targets

31 August 2017

published in

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31 August 2017

volume

18

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31 August 2017

issue

9

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31 August 2017

page(s)

1023-1034

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Remodeling in asthma and chronic obstructive pulmonary disease

31 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

Airway smooth muscle dynamics: a common pathway of airway obstruction in asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

Airway structural alterations selectively associated with severe asthma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

Airway smooth muscle hypertrophy and hyperplasia in asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

Pharmacology of airway smooth muscle proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

Novel non-canonical TGF-β signaling networks: emerging roles in airway smooth muscle phenotype and function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

Increased airway smooth muscle in preschool wheezers who have asthma at school age.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

Increased airway smooth muscle mass in children with asthma, cystic fibrosis, and non-cystic fibrosis bronchiectasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

Maternal smoking during pregnancy induces airway remodelling in mice offspring.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

Maternal smoking during pregnancy decreases Wnt signalling in neonatal mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

WNT signaling in lung disease: a failure or a regeneration signal?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

The many faces and functions of β-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

The WNT signaling pathway from ligand secretion to gene transcription: molecular mechanisms and pharmacological targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

Inhibition of GSK3 by Wnt signalling--two contrasting models

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

Wnt signaling requires sequestration of glycogen synthase kinase 3 inside multivesicular endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

Glycogen synthase kinase 3: a key regulator of cellular fate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

GSK-3/beta-catenin signaling axis in airway smooth muscle: role in mitogenic signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

β-Catenin signaling is required for TGF-β1-induced extracellular matrix production by airway smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

Activation of WNT/β-catenin signaling in pulmonary fibroblasts by TGF-β₁ is increased in chronic obstructive pulmonary disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

De novo synthesis of {beta}-catenin via H-Ras and MEK regulates airway smooth muscle growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

Nuclear β-catenin accumulation is associated with increased expression of Nanog protein and predicts poor prognosis of non-small cell lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

Parabronchial smooth muscle constitutes an airway epithelial stem cell niche in the mouse lung after injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

Beta-catenin hits chromatin: regulation of Wnt target gene activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

Beta-catenin/T-cell factor signaling is activated during lung injury and promotes the survival and migration of alveolar epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

Interactions between β-catenin and transforming growth factor-β signaling pathways mediate epithelial-mesenchymal transition and are dependent on the transcriptional co-activator cAMP-response element-binding protein (CREB)-binding protein (CBP).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

Induction of a mesenchymal expression program in lung epithelial cells by wingless protein (Wnt)/β-catenin requires the presence of c-Jun N-terminal kinase-1 (JNK1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

Nicotine-induced epithelial-mesenchymal transition via Wnt/β-catenin signaling in human airway epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

Inhibition of Wnt/beta-catenin/CREB binding protein (CBP) signaling reverses pulmonary fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

Role of β-catenin-regulated CCN matricellular proteins in epithelial repair after inflammatory lung injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

TGF-β-activated kinase 1 (TAK1) signaling regulates TGF-β-induced WNT-5A expression in airway smooth muscle cells via Sp1 and β-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

Wnt signaling regulates smooth muscle precursor development in the mouse lung via a tenascin C/PDGFR pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

beta-Catenin promotes respiratory progenitor identity in mouse foregut

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

Formation and differentiation of multiple mesenchymal lineages during lung development is regulated by beta-catenin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

Dickkopf-1 (DKK1) reveals that fibronectin is a major target of Wnt signaling in branching morphogenesis of the mouse embryonic lung.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

c-Myc regulates proliferation and Fgf10 expression in airway smooth muscle after airway epithelial injury in mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

A role for Wnt signaling genes in the pathogenesis of impaired lung function in asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

Cross-talk between transforming growth factor-β₁ and muscarinic M₂ receptors augments airway smooth muscle proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

TGF-beta1 increases proliferation of airway smooth muscle cells by phosphorylation of map kinases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

β-Catenin determines upper airway progenitor cell fate and preinvasive squamous lung cancer progression by modulating epithelial-mesenchymal transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

Epithelial-mesenchymal transition in the pathophysiology of airway remodelling in asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

TGF-beta-induced EMT: mechanisms and implications for fibrotic lung disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

House dust mite-promoted epithelial-to-mesenchymal transition in human bronchial epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

Integrin alpha3beta1-dependent beta-catenin phosphorylation links epithelial Smad signaling to cell contacts

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

Airway structural components drive airway smooth muscle remodeling in asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

Wnt3a induces myofibroblast differentiation by upregulating TGF-β signaling through SMAD2 in a β-catenin-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

Noncanonical WNT-5A signaling regulates TGF-β-induced extracellular matrix production by airway smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

Extracellular matrix proteins differentially regulate airway smooth muscle phenotype and function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

Biomechanical regulation of mesenchymal cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

Chronic effects of mechanical force on airways

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

Bronchoconstriction Induces TGF-β Release and Airway Remodelling in Guinea Pig Lung Slices

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

Integrin αvβ5-mediated TGF-β activation by airway smooth muscle cells in asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

Mechanotransduction through growth-factor shedding into the extracellular space

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

A multiwell platform for studying stiffness-dependent cell biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

Regulation of cell-cell adhesion by the cadherin-catenin complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

Focal adhesion kinase regulation of mechanotransduction and its impact on endothelial cell functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

Focal adhesion kinase is required for β-catenin-induced mobilization of epidermal stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

Focal adhesion kinase mediates β-catenin signaling in periodontal ligament cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

A diterpenoid compound, excisanin A, inhibits the invasive behavior of breast cancer cells by modulating the integrin β1/FAK/PI3K/AKT/β-catenin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

Integration of the beta-catenin-dependent Wnt pathway with integrin signaling through the adaptor molecule Grb2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

Rac1 and Cdc42 GTPases regulate shear stress-driven β-catenin signaling in osteoblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

Mechanical induction of Twist in the Drosophila foregut/stomodeal primordium

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

Role of TAZ as mediator of Wnt signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

{beta}-Catenin regulates airway smooth muscle contraction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

Axin pathway activity regulates in vivo pY654-β-catenin accumulation and pulmonary fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

Inactivation of tankyrases reduces experimental fibrosis by inhibiting canonical Wnt signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

GSK-3: tricks of the trade for a multi-tasking kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

The selectivity of protein kinase inhibitors: a further update

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

Glycogen synthase kinase-3 (GSK-3) regulates TGF-β₁-induced differentiation of pulmonary fibroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

Glycogen synthase kinase-3 regulates cigarette smoke extract- and IL-1β-induced cytokine secretion by airway smooth muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

Pharmacological inhibition of GSK-3 in a guinea pig model of LPS-induced pulmonary inflammation: I. Effects on lung remodeling and pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

Activation of the WNT/β-catenin pathway attenuates experimental emphysema

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

Considerations for targeting β-catenin signaling in fibrosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

A small molecule inhibitor of beta-catenin/CREB-binding protein transcription [corrected]

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

Wnt/beta-catenin/CBP signaling maintains long-term murine embryonic stem cell pluripotency

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

Targeted inhibition of β-catenin/CBP signaling ameliorates renal interstitial fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

Glycogen Synthase Kinase-3β Inhibition Attenuates Asthma in Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.934813

10.1517/14728222.2014.934813

21 January 2018

Identifiers

DOI

1 reference

31 August 2017

1 reference