(Q54484446)

30 May 2018

title

Focal adhesion kinase is required for β-catenin-induced mobilization of epidermal stem cells. (English)

1 reference

30 May 2018

author

Owen J Sansom

8

1 reference

30 May 2018

Susan Mason

object named as

Susan Mason

3

0 references

Bryan Serrels

2

object named as

Bryan Serrels

1 reference

30 May 2018

author name string

Rachel A Ridgway

1

1 reference

30 May 2018

Andrew Kinnaird

4

1 reference

30 May 2018

Morwenna Muir

5

1 reference

30 May 2018

Hitesh Patel

6

1 reference

30 May 2018

William J Muller

7

1 reference

30 May 2018

Valerie G Brunton

9

1 reference

30 May 2018

language of work or name

English

0 references

publication date

12 September 2012

1 reference

30 May 2018

published in

Carcinogenesis

1 reference

30 May 2018

volume

33

1 reference

30 May 2018

issue

12

1 reference

30 May 2018

page(s)

2369-2376

1 reference

30 May 2018

FAK regulates biological processes important for the pathogenesis of cancer

cites work

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS284

The signaling and biological implications of FAK overexpression in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS284

Src and focal adhesion kinase as therapeutic targets in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS284

Focal adhesion kinase: targeting adhesion signaling pathways for therapeutic intervention

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS284

Control of motile and invasive cell phenotypes by focal adhesion kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS284

Mammary epithelial-specific disruption of the focal adhesion kinase blocks mammary tumor progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS284

Specific deletion of focal adhesion kinase suppresses tumor formation and blocks malignant progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS284

Epidermal stem cells of the skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS284

Controlling the stem cell niche: right time, right place, right strength.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS284

Wnt signalling in stem cells and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS284

Epidermal stem cells: an update

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS284

Cutaneous cancer stem cell maintenance is dependent on beta-catenin signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS284

Intestinal polyposis in mice with a dominant stable mutation of the beta-catenin gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS284

Mammary epithelial-specific disruption of c-Src impairs cell cycle progression and tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS284

A novel Src kinase inhibitor reduces tumour formation in a skin carcinogenesis model

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS284

Beta-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS284

Manipulation of stem cell proliferation and lineage commitment: visualisation of label-retaining cells in wholemounts of mouse epidermis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS284

Label-retaining cells reside in the bulge area of pilosebaceous unit: implications for follicular stem cells, hair cycle, and skin carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS284

Stem-cell hierarchy in skin cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS284

Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS284

Epidermal label-retaining cells: background and recent applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS284

A perspective on murine keratinocyte stem cells as targets of chemically induced skin cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS284

Integrin-regulated FAK-Src signaling in normal and cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS284

Focal adhesion kinase: the first ten years

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS284

Dasatinib, an orally active small molecule inhibitor of both the src and abl kinases, selectively inhibits growth of basal-type/"triple-negative" breast cancer cell lines growing in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS284

Overexpression of a constitutively active form of c-src in skin epidermis increases sensitivity to tumor promotion by 12-O-tetradecanoylphorbol-13-acetate

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS284

C-terminal Src kinase controls development and maintenance of mouse squamous epithelia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS284

Combined deficiencies of Src, Fyn, and Yes tyrosine kinases in mutant mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS284

Discovery of a new class of anilinoquinazoline inhibitors with high affinity and specificity for the tyrosine kinase domain of c-Src

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS284

Evolving molecular therapy for chronic myeloid leukaemia--are we on target?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS284

Integration of the beta-catenin-dependent Wnt pathway with integrin signaling through the adaptor molecule Grb2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS284

Focal adhesion kinase protein regulates Wnt3a gene expression to control cell fate specification in the developing neural plate

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS284

Actomyosin-mediated cellular tension drives increased tissue stiffness and β-catenin activation to induce epidermal hyperplasia and tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS284

Continuous tooth generation in mouse is induced by activated epithelial Wnt/beta-catenin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS284

Transient activation of beta-catenin signalling in adult mouse epidermis is sufficient to induce new hair follicles but continuous activation is required to maintain hair follicle tumours.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS284

Transient activation of beta -catenin signaling in cutaneous keratinocytes is sufficient to trigger the active growth phase of the hair cycle in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS284

c-Myc activation in transgenic mouse epidermis results in mobilization of stem cells and differentiation of their progeny

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS284

Deregulated expression of c-Myc depletes epidermal stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS284

Hair cycle and wound healing in mice with a keratinocyte-restricted deletion of FAK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS284

WNT signals are required for the initiation of hair follicle development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS284

De Novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS284

beta-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS284

Defining the impact of beta-catenin/Tcf transactivation on epithelial stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS284

Beta-catenin and Hedgehog signal strength can specify number and location of hair follicles in adult epidermis without recruitment of bulge stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS284

SKI-606 decreases growth and motility of colorectal cancer cells by preventing pp60(c-Src)-dependent tyrosine phosphorylation of beta-catenin and its nuclear signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS284

Active Src elevates the expression of beta-catenin by enhancement of cap-dependent translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS284

Dishevelled-2 docks and activates Src in a Wnt-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS284

Skin epidermis lacking the c-Myc gene is resistant to Ras-driven tumorigenesis but can reacquire sensitivity upon additional loss of the p21Cip1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS284

Focal adhesion kinase is required for intestinal regeneration and tumorigenesis downstream of Wnt/c-Myc signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS284

Tumor-initiating stem cells of squamous cell carcinomas and their control by TGF-β and integrin/focal adhesion kinase (FAK) signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS284

21 January 2018

Identifiers

DOI

10.1093/CARCIN/BGS284

1 reference

30 May 2018

PubMed ID

22971575

1 reference

30 May 2018