(Q38233472)

31 August 2017

title

Epigenetic reprogramming in breast cancer: from new targets to new therapies (English)

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31 August 2017

Tiffany A Katz

1

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31 August 2017

Yi Huang

series ordinal

2

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31 August 2017

Nancy E Davidson

series ordinal

3

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31 August 2017

Rachel C Jankowitz

series ordinal

4

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31 August 2017

language of work or name

English

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publication date

24 July 2014

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31 August 2017

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31 August 2017

volume

46

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31 August 2017

issue

6

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31 August 2017

page(s)

397-408

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CpG-rich islands and the function of DNA methylation

31 August 2017

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EZH2 inhibition decreases p38 signaling and suppresses breast cancer motility and metastasis

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Lysine-specific demethylase 1 (LSD1) is highly expressed in ER-negative breast cancers and a biomarker predicting aggressive biology

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Polyamine analogues targeting epigenetic gene regulation

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Elevated expression of LSD1 (Lysine-specific demethylase 1) during tumour progression from pre-invasive to invasive ductal carcinoma of the breast

21 January 2018

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KDM1B is a histone H3K4 demethylase required to establish maternal genomic imprints

21 January 2018

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Histone demethylase KDM6B promotes epithelial-mesenchymal transition

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microRNA-7 suppresses the invasive potential of breast cancer cells and sensitizes cells to DNA damages by targeting histone methyltransferase SET8

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Epigenetic reprogramming during early development in mammals.

21 January 2018

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Compensatory mammary growth following protein restriction during pregnancy and lactation increases early-onset mammary tumor incidence in rats.

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High-fat or ethinyl-oestradiol intake during pregnancy increases mammary cancer risk in several generations of offspring

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21 January 2018

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21 January 2018

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21 January 2018

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Mild folate deficiency induces genetic and epigenetic instability and phenotype changes in prostate cancer cells

21 January 2018

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21 January 2018

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Associations of dietary folate, Vitamins B6 and B12 and methionine intake with risk of breast cancer among African American and European American women

21 January 2018

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Dietary intake of B vitamins and methionine and breast cancer risk

21 January 2018

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Dietary intake of folate, B-vitamins and methionine and breast cancer risk among Hispanic and non-Hispanic white women

21 January 2018

1 reference

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21 January 2018

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Sulforaphane induces cell type-specific apoptosis in human breast cancer cell lines

21 January 2018

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Anticarcinogenic activities of sulforaphane and structurally related synthetic norbornyl isothiocyanates

21 January 2018

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Relevance of anti-inflammatory and antioxidant activities of exemestane and synergism with sulforaphane for disease prevention

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890.2014.923740

Epigenotyping in peripheral blood cell DNA and breast cancer risk: a proof of principle study

21 January 2018

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DNA methylation in peripheral blood measured by LUMA is associated with breast cancer in a population-based study

21 January 2018

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Familial and racial determinants of tumour suppressor genes promoter hypermethylation in breast tissues from healthy women.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890.2014.923740

Epigenome-wide association study of breast cancer using prospectively collected sister study samples

21 January 2018

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https://api.crossref.org/works/10.3109%2F07853890.2014.923740

Frequent epigenetic inactivation of Wnt antagonist genes in breast cancer

21 January 2018

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Delivery of 5-aza-2'-deoxycytidine to cells using oligodeoxynucleotides

21 January 2018

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21 January 2018

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https://api.crossref.org/works/10.3109%2F07853890.2014.923740

Effects of a novel DNA methyltransferase inhibitor zebularine on human breast cancer cells

21 January 2018

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A novel histone deacetylase inhibitor, scriptaid, enhances expression of functional estrogen receptor alpha (ER) in ER negative human breast cancer cells in combination with 5-aza 2'-deoxycytidine.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890.2014.923740

Histone deacetylase inhibitor LBH589 reactivates silenced estrogen receptor alpha (ER) gene expression without loss of DNA hypermethylation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890.2014.923740

Inhibitor scaffold for the histone lysine demethylase KDM4C (JMJD2C).

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890.2014.923740

Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890.2014.923740

BRCA1-deficient mammary tumor cells are dependent on EZH2 expression and sensitive to Polycomb Repressive Complex 2-inhibitor 3-deazaneplanocin A.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890.2014.923740

Selective inhibition of Ezh2 by a small molecule inhibitor blocks tumor cells proliferation

21 January 2018

1 reference

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EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890.2014.923740

Reexpression of tumor suppressor, sFRP1, leads to antitumor synergy of combined HDAC and methyltransferase inhibitors in chemoresistant cancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890.2014.923740

Highly synergistic effect of sequential treatment with epigenetic and anticancer drugs to overcome drug resistance in breast cancer cells is mediated via activation of p21 gene expression leading to G2/M cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890.2014.923740

Epigenetic reactivation of estrogen receptor-α (ERα) by genistein enhances hormonal therapy sensitivity in ERα-negative breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890.2014.923740

Synergistic effect of paclitaxel and epigenetic agent phenethyl isothiocyanate on growth inhibition, cell cycle arrest and apoptosis in breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890.2014.923740

ING1 and 5-azacytidine act synergistically to block breast cancer cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890.2014.923740

Restoration of tamoxifen sensitivity in estrogen receptor-negative breast cancer cells: tamoxifen-bound reactivated ER recruits distinctive corepressor complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890.2014.923740

A phase II trial of vorinostat (suberoylanilide hydroxamic acid) in metastatic breast cancer: a California Cancer Consortium study

21 January 2018

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Biomarker modulation following short-term vorinostat in women with newly diagnosed primary breast cancer

21 January 2018

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A phase II study of the histone deacetylase inhibitor vorinostat combined with tamoxifen for the treatment of patients with hormone therapy-resistant breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890.2014.923740

Randomized phase II, double-blind, placebo-controlled study of exemestane with or without entinostat in postmenopausal women with locally recurrent or metastatic estrogen receptor-positive breast cancer progressing on treatment with a nonsteroidal a

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890.2014.923740

A proof-of-principle study of epigenetic therapy added to neoadjuvant doxorubicin cyclophosphamide for locally advanced breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890.2014.923740

Phase I-II study of vorinostat plus paclitaxel and bevacizumab in metastatic breast cancer: evidence for vorinostat-induced tubulin acetylation and Hsp90 inhibition in vivo

21 January 2018

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https://api.crossref.org/works/10.3109%2F07853890.2014.923740

Targeting the dynamic HSP90 complex in cancer

21 January 2018

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https://api.crossref.org/works/10.3109%2F07853890.2014.923740

A novel mammalian flavin-dependent histone demethylase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890.2014.923740

Mechanism-based inhibition of C5-cytosine DNA methyltransferases by 2-H pyrimidinone 1 1Edited by J. Karn

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890.2014.923740

10.3109/07853890.2014.923740

21 January 2018

Identifiers

DOI

1 reference

31 August 2017

1 reference