(Q38236893)

31 August 2017

title

Resistance of Candida spp. to antifungal drugs in the ICU: where are we now? (English)

1 reference

31 August 2017

Thierry Calandra

3

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Dominique Sanglard

object named as

Dominique Sanglard

4

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author name string

Danièle Maubon

1

1 reference

31 August 2017

Cécile Garnaud

2

1 reference

31 August 2017

Muriel Cornet

5

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31 August 2017

publication date

5 August 2014

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31 August 2017

published in

Intensive Care Medicine

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31 August 2017

volume

40

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31 August 2017

issue

9

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31 August 2017

page(s)

1241-1255

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Management of invasive candidiasis and candidemia in adult non-neutropenic intensive care unit patients: Part II. Treatment.

31 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Antifungal use influences Candida species distribution and susceptibility in the intensive care unit.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Recent exposure to caspofungin or fluconazole influences the epidemiology of candidemia: a prospective multicenter study involving 2,441 patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Increasing echinocandin resistance in Candida glabrata: clinical failure correlates with presence of FKS mutations and elevated minimum inhibitory concentrations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Caspofungin MICs correlate with treatment outcomes among patients with Candida glabrata invasive candidiasis and prior echinocandin exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Current perspectives on echinocandin class drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Antifungal agents: mechanisms of action

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Effects of fluconazole on the secretome, the wall proteome, and wall integrity of the clinical fungus Candida albicans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Effects of fluconazole on the sterol and carbohydrate composition of four species of Candida

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Amphotericin primarily kills yeast by simply binding ergosterol

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Amphotericin forms an extramembranous and fungicidal sterol sponge.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Molecular basis for the selective toxicity of amphotericin B for yeast and filipin for animal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Amphotericin B formulations: a comparative review of efficacy and toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Fungal echinocandin resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Calcineurin A of Candida albicans: involvement in antifungal tolerance, cell morphogenesis and virulence

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

PKC signaling regulates drug resistance of the fungal pathogen Candida albicans via circuitry comprised of Mkc1, calcineurin, and Hsp90

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Elevated cell wall chitin in Candida albicans confers echinocandin resistance in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Paradoxical growth of Candida albicans in the presence of caspofungin is associated with multiple cell wall rearrangements and decreased virulence

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Breakpoints for antifungal agents: an update from EUCAST focussing on echinocandins against Candida spp. and triazoles against Aspergillus spp.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Genotypic evolution of azole resistance mechanisms in sequential Candida albicans isolates

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Antifungal drug resistance mechanisms in fungal pathogens from the perspective of transcriptional gene regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

A mutation in Tac1p, a transcription factor regulating CDR1 and CDR2, is coupled with loss of heterozygosity at chromosome 5 to mediate antifungal resistance in Candida albicans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Screening for amino acid substitutions in the Candida albicans Erg11 protein of azole-susceptible and azole-resistant clinical isolates: new substitutions and a review of the literature.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Amino acid substitutions in the Candida albicans sterol Δ5,6-desaturase (Erg3p) confer azole resistance: characterization of two novel mutants with impaired virulence

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Formation of new chromosomes as a virulence mechanism in yeast Candida glabrata

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Loss of mitochondrial functions associated with azole resistance in Candida glabrata results in enhanced virulence in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Fitness trade-offs restrict the evolution of resistance to amphotericin B

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Nonsense and missense mutations in FCY2 and FCY1 genes are responsible for flucytosine resistance and flucytosine-fluconazole cross-resistance in clinical isolates of Candida lusitaniae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Reactive oxygen species-inducing antifungal agents and their activity against fungal biofilms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Antifungal susceptibility of Candida biofilms: unique efficacy of amphotericin B lipid formulations and echinocandins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Species-specific differences in the susceptibilities of biofilms formed by Candida bloodstream isolates to echinocandin antifungals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Susceptibility of Candida albicans biofilms grown in a constant depth film fermentor to chlorhexidine, fluconazole and miconazole: a longitudinal study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Mechanisms of Candida biofilm drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Antifungal susceptibility of Candida albicans in biofilms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Role of matrix β-1,3 glucan in antifungal resistance of non-albicans Candida biofilms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Hsp90 governs dispersion and drug resistance of fungal biofilms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Addition of DNase improves the in vitro activity of antifungal drugs against Candida albicans biofilms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

EUCAST definitive document EDef 7.1: method for the determination of broth dilution MICs of antifungal agents for fermentative yeasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Comparison of the Antifungal Susceptibility Testing Subcommittee of the European Committee on Antibiotic Susceptibility Testing proposed standard and the E-test with the NCCLS broth microdilution method for voriconazole and caspofungin susceptibilit

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Comparison of the Vitek 2 antifungal susceptibility system with the clinical and laboratory standards institute (CLSI) and European Committee on Antimicrobial Susceptibility Testing (EUCAST) Broth Microdilution Reference Methods and with the [...]

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Comparative evaluation of Sensititre YeastOne vs. the NCCLS M27A protocol and E-test for antifungal susceptibility testing of yeasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Clinical breakpoints for the echinocandins and Candida revisited: integration of molecular, clinical, and microbiological data to arrive at species-specific interpretive criteria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Breakthrough Aspergillus fumigatus and Candida albicans double infection during caspofungin treatment: laboratory characteristics and implication for susceptibility testing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Wild-type MIC distributions, epidemiological cutoff values and species-specific clinical breakpoints for fluconazole and Candida: time for harmonization of CLSI and EUCAST broth microdilution methods

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Interlaboratory variability of Caspofungin MICs for Candida spp. Using CLSI and EUCAST methods: should the clinical laboratory be testing this agent?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Use of micafungin as a surrogate marker to predict susceptibility and resistance to caspofungin among 3,764 clinical isolates of Candida by use of CLSI methods and interpretive criteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Real-world experience with echinocandin MICs against Candida species in a multicenter study of hospitals that routinely perform susceptibility testing of bloodstream isolates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Evaluation of amphotericin B interpretive breakpoints for Candida bloodstream isolates by correlation with therapeutic outcome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Amphotericin B and caspofungin resistance in Candida glabrata isolates recovered from a critically ill patient

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Rapid antifungal susceptibility determination for yeast isolates by use of Etest performed directly on blood samples from patients with fungemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Pyrosequencing to detect mutations in FKS1 that confer reduced echinocandin susceptibility in Candida albicans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Establishing surrogate markers for fluconazole resistance in Candida albicans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Rapid detection of ERG11 gene mutations in clinical Candida albicans isolates with reduced susceptibility to fluconazole by rolling circle amplification and DNA sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Azole resistance in Aspergillus fumigatus from bronchoalveolar lavage fluid samples of patients with chronic diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Epidemiology, species distribution, antifungal susceptibility, and outcome of candidemia across five sites in Italy and Spain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Candida bloodstream infections: comparison of species distribution and resistance to echinocandin and azole antifungal agents in Intensive Care Unit (ICU) and non-ICU settings in the SENTRY Antimicrobial Surveillance Program (2008-2009).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Impact of therapeutic strategies on the prognosis of candidemia in the ICU.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Epidemiology of invasive fungal infections in the intensive care unit: results of a multicenter Italian survey (AURORA Project)

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

The changing epidemiology of healthcare-associated candidemia over three decades

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Factors associated with candidemia caused by non-albicans Candida species versus Candida albicans in the intensive care unit

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Antimicrobial resistance: resistance to antifungal agents: mechanisms and clinical impact

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Epidemiology of invasive mycoses in North America

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Candida rugosa, an emerging fungal pathogen with resistance to azoles: geographic and temporal trends from the ARTEMIS DISK antifungal surveillance program.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

A naturally occurring proline-to-alanine amino acid change in Fks1p in Candida parapsilosis, Candida orthopsilosis, and Candida metapsilosis accounts for reduced echinocandin susceptibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Killing kinetics of caspofungin, micafungin, and amphotericin B against Candida guilliermondii.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Breakthrough C. parapsilosis and C. guilliermondii blood stream infections in allogeneic hematopoietic stem cell transplant recipients receiving long-term caspofungin therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Breakthrough invasive candidiasis in patients on micafungin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Evolution of antifungal-drug resistance: mechanisms and pathogen fitness

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Frequency of decreased susceptibility and resistance to echinocandins among fluconazole-resistant bloodstream isolates of Candida glabrata

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Changes in incidence and antifungal drug resistance in candidemia: results from population-based laboratory surveillance in Atlanta and Baltimore, 2008-2011.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Novel FKS mutations associated with echinocandin resistance in Candida species

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Caspofungin-resistant Candida tropicalis strains causing breakthrough fungemia in patients at high risk for hematologic malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Emergence of a Candida krusei isolate with reduced susceptibility to caspofungin during therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Rapid emergence of echinocandin resistance during Candida kefyr fungemia treatment with caspofungin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Antifungal drug resistance: mechanisms, epidemiology, and consequences for treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Breakthrough candidemia due to multidrug-resistant Candida glabrata during prophylaxis with a low dose of micafungin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Breakthrough invasive fungal diseases during echinocandin treatment in high-risk hospitalized hematologic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Characterisation of breakthrough invasive mycoses in echinocandin recipients: an evidence-based review

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Positions and numbers of FKS mutations in Candida albicans selectively influence in vitro and in vivo susceptibilities to echinocandin treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Invasive candidiasis in intensive care units in China: in vitro antifungal susceptibility in the China-SCAN study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Acquisition of flucytosine, azole, and caspofungin resistance in Candida glabrata bloodstream isolates serially obtained from a hematopoietic stem cell transplant recipient.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Epidemiology of invasive candidiasis: a persistent public health problem

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

The trend of susceptibilities to amphotericin B and fluconazole of Candida species from 1999 to 2002 in Taiwan

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Antifungal drug resistance of pathogenic fungi.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Candida glabrata, Candida parapsilosis and Candida tropicalis: biology, epidemiology, pathogenicity and antifungal resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Defining responses to therapy and study outcomes in clinical trials of invasive fungal diseases: Mycoses Study Group and European Organization for Research and Treatment of Cancer consensus criteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Liposomal amphotericin B for empirical therapy in patients with persistent fever and neutropenia. National Institute of Allergy and Infectious Diseases Mycoses Study Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Liposomal amphotericin B: a review of its use as empirical therapy in febrile neutropenia and in the treatment of invasive fungal infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Impact of treatment strategy on outcomes in patients with candidemia and other forms of invasive candidiasis: a patient-level quantitative review of randomized trials.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

ESCMID* guideline for the diagnosis and management of Candida diseases 2012: non-neutropenic adult patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

In vitro activities of 5-fluorocytosine against 8,803 clinical isolates of Candida spp.: global assessment of primary resistance using National Committee for Clinical Laboratory Standards susceptibility testing methods.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Tissue penetration of antifungal agents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Practical considerations on current guidelines for the management of non-neutropenic adult patients with candidaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

The presence of an FKS mutation rather than MIC is an independent risk factor for failure of echinocandin therapy among patients with invasive candidiasis due to Candida glabrata

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Acquired resistance to echinocandins in Candida albicans: case report and review

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Early prediction of Candida glabrata fungemia in nonneutropenic critically ill patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Diagnosis and therapy of Candida infections: joint recommendations of the German Speaking Mycological Society and the Paul-Ehrlich-Society for Chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Brazilian guidelines for the management of candidiasis - a joint meeting report of three medical societies: Sociedade Brasileira de Infectologia, Sociedade Paulista de Infectologia and Sociedade Brasileira de Medicina Tropical

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Clinical practice guidelines for the management of candidiasis: 2009 update by the Infectious Diseases Society of America.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Management and diagnostic guidelines for fungal diseases in infectious diseases and clinical microbiology: critical appraisal

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Candidaemia in the non-neutropenic patient: a critique of the guidelines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

A multicenter study of septic shock due to candidemia: outcomes and predictors of mortality.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Clinical practice guidelines for the diagnosis and management of intravascular catheter-related infection: 2009 Update by the Infectious Diseases Society of America

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Molecular Diversity and Routes of Colonization ofCandida albicansin a Surgical Intensive Care Unit, as Studied Using Microsatellite Markers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-014-3404-7

Breakthrough fungemia caused by fluconazole-resistant Candida albicans with decreased susceptibility to voriconazole in patients with hematologic malignancies.

21 January 2018

1 reference

12 December 2020

Candida infections, causes, targets, and resistance mechanisms: traditional and alternative antifungal agents

1 reference

12 December 2020

Elucidating the origins of nosocomial infections with Candida albicans by DNA fingerprinting with the complex probe Ca3.

1 reference

12 December 2020

Assessment of caspofungin susceptibility of Candida glabrata by the Etest®, CLSI, and EUCAST methods, and detection of FKS1 and FKS2 mutations

1 reference

12 December 2020

Recent insights into Candida albicans biofilm resistance mechanisms

1 reference

12 December 2020

Anidulafungin and micafungin MIC breakpoints are superior to that of caspofungin for identifying FKS mutant Candida glabrata strains and Echinocandin resistance

1 reference

12 December 2020

FKS Mutant Candida glabrata: Risk Factors and Outcomes in Patients With Candidemia

1 reference

12 December 2020

Global trends in the distribution of Candida species causing candidemia

1 reference

12 December 2020

What's new in the clinical and diagnostic management of invasive candidiasis in critically ill patients

1 reference

12 December 2020

Canadian clinical practice guidelines for invasive candidiasis in adults

1 reference

12 December 2020

Rapid detection of point mutations by fluorescence resonance energy transfer and probe melting curves in Candida species

1 reference

12 December 2020

Invasive infections due to Candida norvegensis and Candida inconspicua: report of 12 cases and review of the literature.

1 reference

12 December 2020

ECIL 3-2009 update guidelines for antifungal management

1 reference

12 December 2020

Development of a Luminex-based multiplex assay for detection of mutations conferring resistance to Echinocandins in Candida glabrata

1 reference

12 December 2020

10.1007/S00134-014-3404-7

Identifiers

DOI

1 reference

31 August 2017

1 reference