(Q38237617)

31 August 2017

Preparing the ground for tissue regeneration: from mechanism to therapy (English)

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31 August 2017

2

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31 August 2017

Stuart J Forbes

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language of work or name

English

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publication date

1 August 2014

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31 August 2017

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31 August 2017

20

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31 August 2017

8

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31 August 2017

857-869

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https://scigraph.springernature.com/pub.10.1038/nm.3653

31 August 2017

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cites work

Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010

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A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish

21 January 2018

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Neutrophil recruitment and function in health and inflammation

21 January 2018

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Neutrophil-delivered myeloperoxidase dampens the hydrogen peroxide burst after tissue wounding in zebrafish.

21 January 2018

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Mast cells, glia and neuroinflammation: partners in crime?

21 January 2018

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Mast cell activity in the healing wound: more than meets the eye?

21 January 2018

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Tolerance and M2 (alternative) macrophage polarization are related processes orchestrated by p50 nuclear factor kappaB.

21 January 2018

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The M1 and M2 paradigm of macrophage activation: time for reassessment

21 January 2018

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Macrophage biology in development, homeostasis and disease

21 January 2018

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Exploring the full spectrum of macrophage activation

21 January 2018

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Tissue-resident macrophages

21 January 2018

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IL-4 directly signals tissue-resident macrophages to proliferate beyond homeostatic levels controlled by CSF-1

21 January 2018

1 reference

Local macrophage proliferation, rather than recruitment from the blood, is a signature of TH2 inflammation

21 January 2018

1 reference

Live imaging reveals differing roles of macrophages and neutrophils during zebrafish tail fin regeneration

21 January 2018

1 reference

Origin of the blastema in regenerating limbs of the newt Triturus viridescens. An autoradiographic study using tritiated thymidine to follow cell proliferation and migration

21 January 2018

1 reference

Pericytes: developmental, physiological, and pathological perspectives, problems, and promises

21 January 2018

1 reference

Perivascular multi-lineage progenitor cells in human organs: regenerative units, cytokine sources or both?

21 January 2018

1 reference

Lineage tracing and genetic ablation of ADAM12(+) perivascular cells identify a major source of profibrotic cells during acute tissue injury

21 January 2018

1 reference

Pericytes and perivascular fibroblasts are the primary source of collagen-producing cells in obstructive fibrosis of the kidney

21 January 2018

1 reference

Targeting of αv integrin identifies a core molecular pathway that regulates fibrosis in several organs

21 January 2018

1 reference

A pericyte origin of spinal cord scar tissue

21 January 2018

1 reference

Liver fibrosis and repair: immune regulation of wound healing in a solid organ

21 January 2018

1 reference

Pericytes resident in postnatal skeletal muscle differentiate into muscle fibres and generate satellite cells

21 January 2018

1 reference

Dll4 and PDGF-BB convert committed skeletal myoblasts to pericytes without erasing their myogenic memory.

21 January 2018

1 reference

Transplantation of human pericyte progenitor cells improves the repair of infarcted heart through activation of an angiogenic program involving micro-RNA-132

21 January 2018

1 reference

Perivascular ancestors of adult multipotent stem cells

21 January 2018

1 reference

Regulatory T cells exert checks and balances on self tolerance and autoimmunity

21 January 2018

1 reference

Regulatory T cells: mechanisms of differentiation and function

21 January 2018

1 reference

A special population of regulatory T cells potentiates muscle repair

21 January 2018

1 reference

Regulatory T cells in nonlymphoid tissues

21 January 2018

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Regulatory T cells ameliorate cardiac remodeling after myocardial infarction

21 January 2018

1 reference

21 January 2018

1 reference

Activation of stem cells in hepatic diseases.

21 January 2018

1 reference

Eosinophils secrete IL-4 to facilitate liver regeneration

21 January 2018

1 reference

Inductive angiocrine signals from sinusoidal endothelium are required for liver regeneration

21 January 2018

1 reference

Divergent angiocrine signals from vascular niche balance liver regeneration and fibrosis.

21 January 2018

1 reference

Hedgehog signaling is critical for normal liver regeneration after partial hepatectomy in mice

21 January 2018

1 reference

Macrophage-derived Wnt opposes Notch signaling to specify hepatic progenitor cell fate in chronic liver disease.

21 January 2018

1 reference

Links between hepatic fibrosis, ductular reaction, and progenitor cell expansion

21 January 2018

1 reference

Human hepatic lipocytes synthesize tissue inhibitor of metalloproteinases-1. Implications for regulation of matrix degradation in liver

21 January 2018

1 reference

Mechanisms of spontaneous resolution of rat liver fibrosis. Hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inhibitors

21 January 2018

1 reference

Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis

21 January 2018

1 reference

Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair

21 January 2018

1 reference

Differential Ly-6C expression identifies the recruited macrophage phenotype, which orchestrates the regression of murine liver fibrosis

21 January 2018

1 reference

Bone marrow injection stimulates hepatic ductular reactions in the absence of injury via macrophage-mediated TWEAK signaling

21 January 2018

1 reference

Liver progenitor cells yield functional hepatocytes in response to chronic liver injury in mice.

21 January 2018

1 reference

Regeneration of liver after extreme hepatocyte loss occurs mainly via biliary transdifferentiation in zebrafish

21 January 2018

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Extensive conversion of hepatic biliary epithelial cells to hepatocytes after near total loss of hepatocytes in zebrafish

21 January 2018

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In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration.

21 January 2018

1 reference

Robust cellular reprogramming occurs spontaneously during liver regeneration.

21 January 2018

1 reference

Hippo pathway activity influences liver cell fate

21 January 2018

1 reference

Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts

21 January 2018

1 reference

Identification of stem cells in small intestine and colon by marker gene Lgr5

21 January 2018

1 reference

Lgr5(+ve) stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro

21 January 2018

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Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling

21 January 2018

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Intestinal crypt homeostasis revealed at single-stem-cell level by in vivo live imaging.

21 January 2018

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Interconversion between intestinal stem cell populations in distinct niches

21 January 2018

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A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable

21 January 2018

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Functional engraftment of colon epithelium expanded in vitro from a single adult Lgr5⁺ stem cell.

21 January 2018

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Isolation and in vitro expansion of human colonic stem cells.

21 January 2018

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A multicellular approach forms a significant amount of tissue-engineered small intestine in the mouse

21 January 2018

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Regulation of homeostasis and inflammation in the intestine

21 January 2018

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Activated macrophages are an adaptive element of the colonic epithelial progenitor niche necessary for regenerative responses to injury

21 January 2018

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Activation of the epidermal growth factor receptor in macrophages regulates cytokine production and experimental colitis.

21 January 2018

1 reference

Efficient colonic mucosal wound repair requires Trem2 signaling

21 January 2018

1 reference

GM-CSF produced by nonhematopoietic cells is required for early epithelial cell proliferation and repair of injured colonic mucosa

21 January 2018

1 reference

Differential roles of macrophages in diverse phases of skin repair.

21 January 2018

1 reference

Sterile inflammation - do innate lymphoid cell subsets play a role?

21 January 2018

1 reference

Stromal cells in tissue homeostasis: balancing regeneration and fibrosis.

21 January 2018

1 reference

Immune system modulation of kidney regeneration--mechanisms and implications.

21 January 2018

1 reference

Renal progenitors: an evolutionary conserved strategy for kidney regeneration

21 January 2018

1 reference

New tides: using zebrafish to study renal regeneration

21 January 2018

1 reference

Identification of human epididymis protein-4 as a fibroblast-derived mediator of fibrosis

21 January 2018

1 reference

Colony-stimulating factor-1 promotes kidney growth and repair via alteration of macrophage responses

21 January 2018

1 reference

Impact of ageing on muscle cell regeneration

21 January 2018

1 reference

The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions

21 January 2018

1 reference

Regulatory interactions between muscle and the immune system during muscle regeneration

21 January 2018

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Differentially activated macrophages orchestrate myogenic precursor cell fate during human skeletal muscle regeneration

21 January 2018

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Shifts in macrophage phenotypes and macrophage competition for arginine metabolism affect the severity of muscle pathology in muscular dystrophy

21 January 2018

1 reference

Macrophages recruited via CCR2 produce insulin-like growth factor-1 to repair acute skeletal muscle injury

21 January 2018

1 reference

Tumour-associated macrophages are a distinct M2 polarised population promoting tumour progression: potential targets of anti-cancer therapy

21 January 2018

1 reference

Inflammatory monocytes recruited after skeletal muscle injury switch into antiinflammatory macrophages to support myogenesis

21 January 2018

1 reference

A CREB-C/EBPbeta cascade induces M2 macrophage-specific gene expression and promotes muscle injury repair

21 January 2018

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Interleukin-10 reduces the pathology of mdx muscular dystrophy by deactivating M1 macrophages and modulating macrophage phenotype

21 January 2018

1 reference

Leukocyte behavior in atherosclerosis, myocardial infarction, and heart failure

21 January 2018

1 reference

The dynamic lives of macrophage and dendritic cell subsets in atherosclerosis

21 January 2018

1 reference

An abundant tissue macrophage population in the adult murine heart with a distinct alternatively-activated macrophage profile

21 January 2018

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Embryonic and adult-derived resident cardiac macrophages are maintained through distinct mechanisms at steady state and during inflammation

21 January 2018

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CSF-1, IGF-1, and the control of postnatal growth and development

21 January 2018

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Enhancing repair of the mammalian heart

21 January 2018

1 reference

Regulation of cardiac microRNAs by bone marrow mononuclear cell therapy in myocardial infarction

21 January 2018

1 reference

Modified mRNA directs the fate of heart progenitor cells and induces vascular regeneration after myocardial infarction

21 January 2018

1 reference

Myocardial regeneration: expanding the repertoire of thymosin β4 in the ischemic heart

21 January 2018

1 reference

Cardiac regenerative capacity and mechanisms

21 January 2018

1 reference

Transient regenerative potential of the neonatal mouse heart

21 January 2018

1 reference

Regulation of neonatal and adult mammalian heart regeneration by the miR-15 family.

21 January 2018

1 reference

Complete cardiac regeneration in a mouse model of myocardial infarction

21 January 2018

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Ex vivo activated human macrophages improve healing, remodeling, and function of the infarcted heart.

21 January 2018

1 reference

Mesenchymal stem cells reciprocally regulate the M1/M2 balance in mouse bone marrow-derived macrophages

21 January 2018

1 reference

Remyelination in the CNS: from biology to therapy

21 January 2018

1 reference

Individual oligodendrocytes have only a few hours in which to generate new myelin sheaths in vivo

21 January 2018

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Neuronal activity promotes oligodendrogenesis and adaptive myelination in the mammalian brain.

21 January 2018

1 reference

Microglia and monocyte-derived macrophages: functionally distinct populations that act in concert in CNS plasticity and repair

21 January 2018

1 reference

Recruitment of beneficial M2 macrophages to injured spinal cord is orchestrated by remote brain choroid plexus

21 January 2018

1 reference

The glial scar-monocyte interplay: a pivotal resolution phase in spinal cord repair

21 January 2018

1 reference

M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination

21 January 2018

1 reference

Activation of microglia by aggregated beta-amyloid or lipopolysaccharide impairs MHC-II expression and renders them cytotoxic whereas IFN-gamma and IL-4 render them protective.

21 January 2018

1 reference

Synergy between immune cells and adult neural stem/progenitor cells promotes functional recovery from spinal cord injury

21 January 2018

1 reference

Emerging roles for integrated imaging modalities in cardiovascular cell-based therapeutics: a clinical perspective

21 January 2018

1 reference

An overview of methods for the in vivo evaluation of tissue-engineered skin constructs

21 January 2018

1 reference

Unbiased screening of polymer libraries to define novel substrates for functional hepatocytes with inducible drug metabolism

21 January 2018

1 reference

Hematopoietic stem cell niche maintenance during homeostasis and regeneration

21 January 2018

1 reference

Cell therapy for cardiac repair--lessons from clinical trials.

21 January 2018

1 reference

Intramyocardial autologous cell engraftment in patients with ischaemic heart failure: a meta-analysis of randomised controlled trials

21 January 2018

1 reference

The rise of cell therapy trials for stroke: review of published and registered studies

21 January 2018

1 reference

Clinical evidence for the regression of liver fibrosis

21 January 2018

1 reference

Barriers to the successful treatment of liver disease by hepatocyte transplantation

21 January 2018

1 reference

Macrophage therapy for murine liver fibrosis recruits host effector cells improving fibrosis, regeneration, and function.

21 January 2018

1 reference

Liver sinusoidal endothelial cell progenitor cells promote liver regeneration in rats

21 January 2018

1 reference

Toward the development of a global induced pluripotent stem cell library

21 January 2018

1 reference

Interleukin-10 From Transplanted Bone Marrow Mononuclear Cells Contributes to Cardiac Protection After Myocardial Infarction

21 January 2018

1 reference

Regulation of hepatic stellate cell differentiation by the neurotrophin receptor p75NTR

21 January 2018

1 reference

12 December 2020

Significance and therapeutic potential of endothelial progenitor cell transplantation in a cirrhotic liver rat model

1 reference

12 December 2020

Origin and function of myofibroblasts in kidney fibrosis

1 reference

12 December 2020

Scar-associated macrophages are a major source of hepatic matrix metalloproteinase-13 and facilitate the resolution of murine hepatic fibrosis

1 reference

12 December 2020

Remodelling of extracellular matrix is a requirement for the hepatic progenitor cell response

1 reference

12 December 2020

Augmentation of the early phase of liver regeneration after 70% partial hepatectomy in rats following selective Kupffer cell depletion

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12 December 2020

Kupffer cell depletion by CI2MDP-liposomes alters hepatic cytokine expression and delays liver regeneration after partial hepatectomy

1 reference

12 December 2020

Ly6ChiMonocytes Direct Alternatively Activated Profibrotic Macrophage Regulation of Lung Fibrosis

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12 December 2020

Capillary and arteriolar pericytes attract innate leukocytes exiting through venules and 'instruct' them with pattern-recognition and motility programs

1 reference

12 December 2020

Endothelial Cell-Derived Angiopoietin-2 Controls Liver Regeneration as a Spatiotemporal Rheostat

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12 December 2020

Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium

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12 December 2020

Serial transplantation reveals the stem-cell-like regenerative potential of adult mouse hepatocytes

1 reference

12 December 2020

Macrophages - sensors and effectors coordinating skin damage and repair

1 reference

12 December 2020

Mutation in collagen-1 that confers resistance to the action of collagenase results in failure of recovery from CCl4-induced liver fibrosis, persistence of activated hepatic stellate cells, and diminished hepatocyte regeneration

1 reference

12 December 2020

Ex vivo programmed macrophages ameliorate experimental chronic inflammatory renal disease

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12 December 2020

ED2+ macrophages increase selectively myoblast proliferation in muscle cultures

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12 December 2020

Protective Autoimmunity: A Unifying Model for the Immune Network Involved in CNS Repair.

1 reference

12 December 2020

Delayed angiogenesis and VEGF production in CCR2-/- mice during impaired skeletal muscle regeneration

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12 December 2020

Dynamics of normal and injured human liver regeneration after hepatectomy as assessed on the basis of computed tomography and liver function

1 reference

12 December 2020

Nonparenchymal cells from regenerating rat liver generate interleukin-1alpha and -1beta: a mechanism of negative regulation of hepatocyte proliferation

1 reference

12 December 2020

Polysialic acid/neural cell adhesion molecule modulates the formation of ductular reactions in liver injury.

1 reference

12 December 2020

Identifiers

DOI

10.1038/NM.3653

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31 August 2017

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PubMed ID

25100531