(Q38241190)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25136356%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

title

Targeting angiogenesis and tumor microenvironment in metastatic colorectal cancer: role of aflibercept (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25136356%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

1 reference

metastatic colon cancer

1 reference

1 reference

1

1 reference

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13 March 2020

Pietro Parcesepe

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25136356%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Andrea Remo

9

1 reference

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13 March 2020

Massimo Pancione

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25136356%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

author name string

Antonio Febbraro

2

1 reference

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13 March 2020

Michele Venditti

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25136356%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Serena Campidoglio

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25136356%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Nunzio Olivieri

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25136356%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Katia Raieta

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25136356%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Giusy Carmen Imbriani

8

1 reference

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13 March 2020

publication date

21 July 2014

1 reference

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Gastroenterology research and practice

13 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25136356%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

volume

2014

1 reference

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13 March 2020

page(s)

526178

1 reference

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Creative Commons Attribution 3.0 Unported

13 March 2020

copyright license

start time

1 January 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

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6 September 2017

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The colorectal tumor microenvironment: the next decade

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Cancer statistics, 2011: the impact of eliminating socioeconomic and racial disparities on premature cancer deaths

6 September 2017

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XELOX vs FOLFOX-4 as first-line therapy for metastatic colorectal cancer: NO16966 updated results.

6 September 2017

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6 September 2017

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Aflibercept (VEGF Trap): one more double-edged sword of anti-VEGF therapy for cancer?

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6 September 2017

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6 September 2017

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6 September 2017

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Angiogenesis in colorectal cancer: prognostic and therapeutic implications

6 September 2017

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Angiogenesis as a therapeutic target

6 September 2017

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6 September 2017

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Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis

6 September 2017

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6 September 2017

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Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer

6 September 2017

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The adaptor protein shb binds to tyrosine 1175 in vascular endothelial growth factor (VEGF) receptor-2 and regulates VEGF-dependent cellular migration

6 September 2017

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Expression of VEGF-C and VEGF-D at the invasive edge correlates with lymph node metastasis and prognosis of patients with colorectal carcinoma

6 September 2017

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A randomized controlled trial of fluorouracil plus leucovorin, irinotecan, and oxaliplatin combinations in patients with previously untreated metastatic colorectal cancer.

6 September 2017

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Fundamental Concepts of the Angiogenic Process

6 September 2017

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Role of angiogenesis in tumor growth and metastasis

6 September 2017

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Cytokine traps: multi-component, high-affinity blockers of cytokine action

6 September 2017

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Potent VEGF blockade causes regression of coopted vessels in a model of neuroblastoma

6 September 2017

1 reference

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VEGF-Trap: a VEGF blocker with potent antitumor effects

6 September 2017

1 reference

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Vascular growth factors and lymphangiogenesis

6 September 2017

1 reference

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Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer. Irinotecan Study Group

6 September 2017

1 reference

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Vascular-specific growth factors and blood vessel formation

6 September 2017

1 reference

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Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: a multicentre randomised trial

6 September 2017

1 reference

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Angiogenesis and anti-angiogenesis: perspectives for the treatment of solid tumors

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130202

Vascular endothelial growth factor (VEGF) and its receptors

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130202

Vascular endothelial growth factor (VEGF) mRNA isoform expression pattern is correlated with liver metastasis and poor prognosis in colon cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130202

Expression of vascular endothelial growth factor and placenta growth factor in human placenta

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130202

A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130202

Placenta growth factor. Potentiation of vascular endothelial growth factor bioactivity, in vitro and in vivo, and high affinity binding to Flt-1 but not to Flk-1/KDR

6 September 2017

1 reference

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Induction of vascular endothelial growth factor expression by hypoxia and by glucose deficiency in multicell spheroids: implications for tumor angiogenesis

6 September 2017

1 reference

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Tumor angiogenesis: therapeutic implications

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130202

Vascular endothelial growth factor trap blocks tumor growth, metastasis formation, and vascular leakage in an orthotopic murine renal cell cancer model

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130202

Vascular endothelial growth factor trap combined with paclitaxel strikingly inhibits tumor and ascites, prolonging survival in a human ovarian cancer model

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130202

Vascular endothelial growth factor-trap suppresses tumorigenicity of multiple pancreatic cancer cell lines

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130202

Vascular endothelial growth factor-trap decreases tumor burden, inhibits ascites, and causes dramatic vascular remodeling in an ovarian cancer model

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130202

Phase II clinical and pharmacokinetic study of aflibercept in patients with previously treated metastatic colorectal cancer.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130202

Binding and neutralization of vascular endothelial growth factor (VEGF) and related ligands by VEGF Trap, ranibizumab and bevacizumab

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130202

Isolation of a tumor factor responsible for angiogenesis

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130202

Phase I dose-escalation study of intravenous aflibercept administered in combination with irinotecan, 5-fluorouracil and leucovorin in patients with advanced solid tumours

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130202

Macrophage regulation of tumor angiogenesis: implications for cancer therapy.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130202

Placental growth factor neutralising antibodies give limited anti-angiogenic effects in an in vitro organotypic angiogenesis model.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130202

VEGF trap in combination with radiotherapy improves tumor control in u87 glioblastoma.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130202

Overall survival of patients with advanced colorectal cancer correlates with availability of fluorouracil, irinotecan, and oxaliplatin regardless of whether doublet or single-agent therapy is used first line

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130202

Expression of vascular endothelial growth factor and receptor flk-1 in colon cancer liver metastases

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130202

Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130202

Bevacizumab in Combination With Oxaliplatin, Fluorouracil, and Leucovorin (FOLFOX4) for Previously Treated Metastatic Colorectal Cancer: Results From the Eastern Cooperative Oncology Group Study E3200

31 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1155%2F2014%2F526178

Vessel counts and expression of vascular endothelial growth factor as prognostic factors in node-negative colon cancer

21 January 2018

1 reference

12 December 2020

Localisation of placenta growth factor (PIGF) in human term placenta

1 reference

12 December 2020

Elevated perioperative serum vascular endothelial growth factor levels in patients with colon carcinoma

1 reference

12 December 2020

Preoperative serum levels of serum VEGF-C is associated with distant metastasis in colorectal cancer patients

1 reference

12 December 2020

Prognostic value of vascular endothelial growth factor expression in colorectal cancer patients

1 reference

12 December 2020

Expression of vascular endothelial growth factor and its receptor KDR (kinase domain-containing receptor)/Flk-1 (fetal liver kinase-1) as prognostic factors in human colorectal cancer

1 reference

12 December 2020

Stage I colorectal carcinoma: VEGF immunohistochemical expression, microvessel density, and their correlation with clinical outcome

1 reference

12 December 2020

Vascular endothelial growth factors and receptors in colorectal cancer: Implications for anti-angiogenic therapy

1 reference

12 December 2020

Serum vascular endothelial growth factor-C and lymphoangiogenesis are associated with the lymph node metastasis and prognosis of patients with colorectal cancer

1 reference

12 December 2020

Identifiers

DOI

10.1155/2014/526178

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25136356%20AND%20SRC:MED&resulttype=core&format=json

release_4xvvt7i3hferhi7es3sojbz5wu

13 March 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/4xvvt7i3hferhi7es3sojbz5wu

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25136356%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

PubMed publication ID

25136356

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25136356%20AND%20SRC:MED&resulttype=core&format=json