(Q38248535)

1 September 2017

1 reference

title

Targeting 5-lipoxygenase-activating protein in asthma and chronic obstructive pulmonary disease (English)

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chronic obstructive pulmonary disease

1 September 2017

main subject

1 reference

1 reference

Sabina Antonela Antoniu

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25213852%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

author name string

Sabina Antonela Antoniu

series ordinal

1

1 reference

1 September 2017

language of work or name

English

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publication date

12 September 2014

1 reference

Expert Opinion on Therapeutic Targets

1 September 2017

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25213852%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

volume

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25213852%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

issue

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25213852%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

page(s)

1285-1292

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25213852%20AND%20SRC:MED&resulttype=core&format=json

Asthma and chronic obstructive pulmonary disease: similarities and differences

1 June 2020

cites work

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.945425

Cellular and molecular mechanisms of chronic obstructive pulmonary disease

21 January 2018

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Liquid chromatography-mass spectrometry measurement of leukotrienes in asthma and other respiratory diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.945425

LC/MS/MS analysis of leukotriene B4 and other eicosanoids in exhaled breath condensate for assessing lung inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.945425

Effects of montelukast treatment and withdrawal on fractional exhaled nitric oxide and lung function in children with asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.945425

Recent advances in the search for novel 5-lipoxygenase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.945425

Lipid mediators and allergic diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.945425

Pharmacological modulation of the leukotriene pathway in allergic airway disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.945425

Leukotrienes and airway inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.945425

Human bronchial fibroblasts express the 5-lipoxygenase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.945425

Location, location, location: compartmentalization of early events in leukotriene biosynthesis

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2014.945425

Risk-to-benefit ratio of inhaled corticosteroids in patients with COPD.

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2014.945425

New therapeutic options in the management of COPD - focus on roflumilast

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.945425

Lipid peroxidation and 5-lipoxygenase activity in chronic obstructive pulmonary disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.945425

Exhaled leukotrienes and prostaglandins in COPD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.945425

Effects of cyclo-oxygenase inhibition on exhaled eicosanoids in patients with COPD

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.945425

5-lipoxygenase and 5-lipoxygenase-activating protein are localized in the nuclear envelope of activated human leukocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.945425

Effect of a leukotriene B4 receptor antagonist, LY293111, on allergen induced responses in asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.945425

5-Lipoxygenase-activating protein (FLAP) inhibitors. Part 4: development of 3-[3-tert-butylsulfanyl-1-[4-(6-ethoxypyridin-3-yl)benzyl]-5-(5-methylpyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethylpropionic acid (AM803), a potent, oral, once daily FLAP

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.945425

Pharmacology of AM803, a novel selective five-lipoxygenase-activating protein (FLAP) inhibitor in rodent models of acute inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.945425

The 5-lipoxygenase-activating protein inhibitor, GSK2190915, attenuates the early and late responses to inhaled allergen in mild asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.945425

Addition of a 5-lipoxygenase-activating protein inhibitor to an inhaled corticosteroid (ICS) or an ICS/long-acting beta-2-agonist combination in subjects with asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.945425

Efficacy, safety and tolerability of GSK2190915, a 5-lipoxygenase activating protein inhibitor, in adults and adolescents with persistent asthma: a randomised dose-ranging study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.945425

MK-886, an inhibitor of the 5-lipoxygenase-activating protein, inhibits cyclooxygenase-1 activity and suppresses platelet aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.945425

Effect of a leukotriene inhibitor (MK886) on nitric oxide and hydrogen peroxide production by macrophages of acutely and chronically stressed mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.945425

Leukotriene receptor antagonists and synthesis inhibitors reverse survival in eosinophils of asthmatic individuals

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.945425

Reversal of human neutrophil survival by leukotriene B(4) receptor blockade and 5-lipoxygenase and 5-lipoxygenase activating protein inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.945425

Lipoxygenase inhibitor MK886 potentiates TRAIL-induced apoptosis through CHOP- and p38 MAPK-mediated up-regulation of death receptor 5 in malignant glioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.945425

5-Lipoxygenase-activating protein inhibitors. Part 2: 3-{5-((S)-1-Acetyl-2,3-dihydro-1H-indol-2-ylmethoxy)-3-tert-butylsulfanyl-1-[4-(5-methoxy-pyrimidin-2-yl)-benzyl]-1H-indol-2-yl}-2,2-dimethyl-propionic acid (AM679)--a potent FLAP inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.945425

A novel 5-lipoxygenase-activating protein inhibitor, AM679, reduces inflammation in the respiratory syncytial virus-infected mouse eye

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.945425

The novel benzimidazole derivative BRP-7 inhibits leukotriene biosynthesis in vitro and in vivo by targeting 5-lipoxygenase-activating protein (FLAP).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.945425

Attenuation of early and late phase allergen-induced bronchoconstriction in asthmatic subjects by a 5-lipoxygenase activating protein antagonist, BAYx 1005

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.945425

Effect of a novel 5-lipoxygenase activating protein inhibitor, BAYx 1005, on asthma induced by cold dry air.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.945425

Inhibition of allergen-induced airway obstruction and leukotriene generation in atopic asthmatic subjects by the leukotriene biosynthesis inhibitor BAYx 1005

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.945425

Pharmacodynamics and pharmacokinetics of AM103, a novel inhibitor of 5-lipoxygenase-activating protein (FLAP).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.945425

10.1517/14728222.2014.945425

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25213852%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

1 reference