(Q38248809)

1 September 2017

1 reference

title

Plasma and cellular pharmacokinetic considerations for the development and optimization of antitumor block copolymer micelles (English)

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1 September 2017

0 references

1 reference

Jingwei Zhang

1

1 reference

1 September 2017

Jiali Liu

2

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1 September 2017

Yanlei Zhao

3

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1 September 2017

Guangji Wang

4

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1 September 2017

Fang Zhou

5

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1 September 2017

language of work or name

English

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publication date

12 September 2014

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Expert Opinion on Drug Delivery

1 September 2017

published in

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1 September 2017

volume

12

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1 September 2017

issue

2

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1 September 2017

page(s)

263-281

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Block copolymer micelles for delivery of cancer therapy: transport at the whole body, tissue and cellular levels.

1 September 2017

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Multifunctional nanoparticles for combining ultrasonic tumor imaging and targeted chemotherapy.

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The effects of mixed MPEG-PLA/Pluronic copolymer micelles on the bioavailability and multidrug resistance of docetaxel

21 January 2018

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An in vitro study of liposomal curcumin: stability, toxicity and biological activity in human lymphocytes and Epstein-Barr virus-transformed human B-cells

21 January 2018

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Multi-drug loaded polymeric micelles for simultaneous delivery of poorly soluble anticancer drugs.

21 January 2018

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Co-delivery of doxorubicin and plasmid by a novel FGFR-mediated cationic liposome

21 January 2018

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A phase I/II trial of non-pegylated liposomal doxorubicin, docetaxel and trastuzumab as first-line treatment in HER-2-positive locally advanced or metastatic breast cancer

21 January 2018

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Intratumoral drug delivery with nanoparticulate carriers

21 January 2018

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Extracellularly activated nanocarriers: a new paradigm of tumor targeted drug delivery

21 January 2018

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HPMA-based polymer therapeutics improve the efficacy of surgery, of radiotherapy and of chemotherapy combinations

21 January 2018

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Comparative cellular pharmacokinetics and pharmacodynamics of siRNA delivery by SPANosomes and by cationic liposomes

21 January 2018

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Toward a new age of cellular pharmacokinetics in drug discovery

21 January 2018

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Preclinical and clinical studies of anticancer agent-incorporating polymer micelles

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Pharmaceutical nanotechnology: more than size. Ten topics for research

21 January 2018

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The journey of a drug-carrier in the body: an anatomo-physiological perspective

21 January 2018

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Polymeric micelles for delivery of poorly water-soluble compounds

21 January 2018

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Tumor vascular permeability, accumulation, and penetration of macromolecular drug carriers

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Dual-Modal Tumor Imaging via Long-Circulating Biodegradable Core-Crosslinked Polymeric Micelles

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425247.2014.945417

PEGylation improves pharmacokinetic profile, liver uptake and efficacy of Interferon gamma in liver fibrosis.

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Poly(N-vinylpyrrolidone)-block-poly(D,L-lactide) as a new polymeric solubilizer for hydrophobic anticancer drugs: in vitro and in vivo evaluation

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Synthesis and characterization of polyaminoacidic polycations for gene delivery

21 January 2018

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Improving antiangiogenesis and anti-tumor activity of curcumin by biodegradable polymeric micelles

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Core-crosslinked pH-sensitive degradable micelles: A promising approach to resolve the extracellular stability versus intracellular drug release dilemma.

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Stereocomplex block copolymer micelles: core-shell nanostructures with enhanced stability

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Long-circulating poly(ethylene glycol)-poly(D,L-lactide) block copolymer micelles with modulated surface charge

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Cross-linked block copolymer micelles: functional nanostructures of great potential and versatility

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Shell-crosslinked Pluronic L121 micelles as a drug delivery vehicle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Cellular uptake and cytotoxicity of shell crosslinked stearic acid-grafted chitosan oligosaccharide micelles encapsulating doxorubicin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Shell-crosslinked knedel-like nanoparticles induce lower immunotoxicity than their non-crosslinked analogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

A multifunctional envelope type nano device (MEND) for gene delivery to tumours based on the EPR effect: a strategy for overcoming the PEG dilemma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Drug penetration in solid tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Penetration of substances into tumor tissue: a methodological study with microelectrodes and cellular spheroids

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Drug delivery and transport to solid tumors

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Targeted drug delivery to tumors: myths, reality and possibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Antibody tumor penetration: transport opposed by systemic and antigen-mediated clearance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Determinants for in vivo anti-tumor effects of PEG liposomal doxorubicin: importance of vascular permeability within tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Preparation and biological characterization of polymeric micelle drug carriers with intracellular pH-triggered drug release property: tumor permeability, controlled subcellular drug distribution, and enhanced in vivo antitumor efficacy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

The delivery of doxorubicin to 3-D multicellular spheroids and tumors in a murine xenograft model using tumor-penetrating triblock polymeric micelles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

The effects of particle size and molecular targeting on the intratumoral and subcellular distribution of polymeric nanoparticles

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425247.2014.945417

The dawning era of polymer therapeutics

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Photoswitchable nanoparticles for triggered tissue penetration and drug delivery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Photoswitchable nanoparticles for in vivo cancer chemotherapy

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Peptides for specific intracellular delivery and targeting of nanoparticles: implications for developing nanoparticle-mediated drug delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Pluronic block copolymers: evolution of drug delivery concept from inert nanocarriers to biological response modifiers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Pluronic block copolymers for overcoming drug resistance in cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

The drug discovery by nanomedicine and its clinical experience

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Novel mixed polymeric micelles for enhancing delivery of anticancer drug and overcoming multidrug resistance in tumor cell lines simultaneously

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Overcoming cellular multidrug resistance using classical nanomedicine formulations

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Multifunctional polymeric micelles for delivery of drugs and siRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Ligand-directed active tumor-targeting polymeric nanoparticles for cancer chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Tumour-selective drug delivery via folate receptor-targeted liposomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Targeted drug delivery via the folate receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Construction of targeting-clickable and tumor-cleavable polyurethane nanomicelles for multifunctional intracellular drug delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

pH-responsive unimolecular micelles self-assembled from amphiphilic hyperbranched block copolymer for efficient intracellular release of poorly water-soluble anticancer drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Thermo-triggered drug release from actively targeting polymer micelles

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Polysaccharide-decorated nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Enhancement of the cytotoxicity and selectivity of doxorubicin to hepatoma cells by synergistic combination of galactose-decorated γ-poly(glutamic acid) nanoparticles and low-intensity ultrasound.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Paclitaxel-loaded poly(gamma-glutamic acid)-poly(lactide) nanoparticles as a targeted drug delivery system for the treatment of liver cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Intracellular delivery of large molecules and small particles by cell-penetrating proteins and peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

A biodegradable pH-sensitive micelle system for targeting acidic solid tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

TAT peptide-based micelle system for potential active targeting of anti-cancer agents to acidic solid tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Integrins in cancer: biological implications and therapeutic opportunities

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Nanobody-shell functionalized thermosensitive core-crosslinked polymeric micelles for active drug targeting.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Functionalized micelles from block copolymer of polyphosphoester and poly(epsilon-caprolactone) for receptor-mediated drug delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Multifunctional particles for melanoma-targeted drug delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Effect of integrin targeting and PEG shielding on polyplex micelle internalization studied by live-cell imaging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Chimeric aptamers in cancer cell-targeted drug delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Tumor-targeted drug delivery with aptamers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Quantum dot-aptamer conjugates for synchronous cancer imaging, therapy, and sensing of drug delivery based on bi-fluorescence resonance energy transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Targeted delivery of Epirubicin to cancer cells by PEGylated A10 aptamer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Engineering of self-assembled nanoparticle platform for precisely controlled combination drug therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

A new paradigm for aptamer therapeutic AS1411 action: uptake by macropinocytosis and its stimulation by a nucleolin-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Surface expressed nucleolin is constantly induced in tumor cells to mediate calcium-dependent ligand internalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Cell surface nucleolin antagonist causes endothelial cell apoptosis and normalization of tumor vasculature

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Surface nucleolin participates in both the binding and endocytosis of lactoferrin in target cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Aptamer-functionalized PEG-PLGA nanoparticles for enhanced anti-glioma drug delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Antitumor characteristics of methoxypolyethylene glycol-poly(DL-lactic acid) nanoparticles containing camptothecin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Novel polymeric micelles for hydrophobic drug delivery based on biodegradable poly(hexyl-substituted lactides).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

10-Hydroxycamptothecin loaded nanoparticles: preparation and antitumor activity in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Doxorubicin loaded pH-sensitive polymeric micelles for reversal of resistant MCF-7 tumor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Design of Environment‐Sensitive Supramolecular Assemblies for Intracellular Drug Delivery: Polymeric Micelles that are Responsive to Intracellular pH Change

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Multifunctional polymeric micelles with folate-mediated cancer cell targeting and pH-triggered drug releasing properties for active intracellular drug delivery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Block copolymer micelles for drug delivery: design, characterization and biological significance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Healing of articular cartilage defects treated with a novel drug-releasing rod-type implant after microfracture surgery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Multifunctional and stimuli-sensitive pharmaceutical nanocarriers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

A review of stimuli-responsive nanocarriers for drug and gene delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Environmental pH-sensitive polymeric micelles for cancer diagnosis and targeted therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

pH-responsive micelles based on (PCL)2(PDEA-b-PPEGMA)2 miktoarm polymer: controlled synthesis, characterization, and application as anticancer drug carrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Ellagic acid encapsulated chitosan nanoparticles for drug delivery system in human oral cancer cell line (KB).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Evaluation of doxorubicin-loaded pH-sensitive polymeric micelle release from tumor blood vessels and anticancer efficacy using a dorsal skin-fold window chamber model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

pH-triggered drug-releasing magnetic nanoparticles for cancer therapy guided by molecular imaging by MRI.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Doxorubicin-conjugated biodegradable polymeric micelles having acid-cleavable linkages

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Acetal-derivatized dextran: an acid-responsive biodegradable material for therapeutic applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

pH-Sensitive degradable polymersomes for triggered release of anticancer drugs: a comparative study with micelles

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Paclitaxel loaded carrier based biodegradable polymeric implants: Preparation and in vitro characterization

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Novel 4-arm poly(ethylene glycol)-block-poly(anhydride-esters) amphiphilic copolymer micelles loading curcumin: preparation, characterization, and in vitro evaluation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Targeted charge-reversal nanoparticles for nuclear drug delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

pH-responsive nanoparticles for cancer drug delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Proteomics reveals energy and glutathione metabolic dysregulation in the prefrontal cortex of a rat model of depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Dysregulation of glutathione homeostasis in neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Glutathione dysregulation and the etiology and progression of human diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Apoptosis and glutathione: beyond an antioxidant.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Biodegradable micelles with sheddable poly(ethylene glycol) shells for triggered intracellular release of doxorubicin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Shell-sheddable micelles based on dextran-SS-poly(epsilon-caprolactone) diblock copolymer for efficient intracellular release of doxorubicin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

No correlation between GSH levels in human cancer cell lines and the cell growth inhibitory activities of platinum diamine complexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Redox-sensitive disassembly of amphiphilic copolymer based micelles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Targeted drug delivery by thermally responsive polymers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Nanotechnology: a focus on nanoparticles as a drug delivery system

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Thermosensitive and biodegradable polymeric micelles for paclitaxel delivery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Molecular design of biodegradable polymeric micelles for temperature-responsive drug release

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Magnetic resonance imaging of high intensity focused ultrasound mediated drug delivery from temperature-sensitive liposomes: an in vivo proof-of-concept study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

tLyP-1-conjugated Au-nanorod@SiO(2) core-shell nanoparticles for tumor-targeted drug delivery and photothermal therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Targeted cancer theranostics using alpha-tocopheryl succinate-conjugated multifunctional dendrimer-entrapped gold nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Super pH-sensitive multifunctional polymeric micelle for tumor pH(e) specific TAT exposure and multidrug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Multi-stimuli sensitive amphiphilic block copolymer assemblies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Toward the next-generation nanomedicines: design of multifunctional multiblock polyurethanes for effective cancer treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Synthesis, degradation, and cytotoxicity of multiblock poly(epsilon-caprolactone urethane)s containing gemini quaternary ammonium cationic groups

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Intact Doxil is taken up intracellularly and released doxorubicin sequesters in the lysosome: evaluated by in vitro/in vivo live cell imaging

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Determination of doxorubicin levels in whole tumor and tumor nuclei in murine breast cancer tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Current advances in mathematical modeling of anti-cancer drug penetration into tumor tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Polymeric micelles drug delivery system in oncology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Antitumor effect and pharmacokinetics of intraperitoneal NK105, a nanomicellar paclitaxel formulation for peritoneal dissemination

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Preclinical and clinical studies of NK012, an SN-38-incorporating polymeric micelles, which is designed based on EPR effect

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

A Phase I clinical study of cisplatin-incorporated polymeric micelles (NC-6004) in patients with solid tumours.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Effect of combined treatment with the epirubicin-incorporating micelles (NC-6300) and 1,2-diaminocyclohexane platinum (II)-incorporating micelles (NC-4016) on a human gastric cancer model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Ligand-Directed Reduction-Sensitive Shell-Sheddable Biodegradable Micelles Actively Deliver Doxorubicin into the Nuclei of Target Cancer Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

Thermo-responsive drug delivery from polymeric micelles constructed using block copolymers of poly(N-isopropylacrylamide) and poly(butylmethacrylate)

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2014.945417

10.1517/17425247.2014.945417

21 January 2018

Identifiers

DOI

1 reference

1 September 2017

1 reference