(Q38259785)

1 September 2017

Inhibition of PRC2 activity by a gain-of-function H3 mutation found in pediatric glioblastoma (English)

1 reference

1 September 2017

Peter W Lewis

1

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Charles David Allis

10

object named as

C David Allis

1 reference

1 September 2017

Manuel M Müller

2

1 reference

1 September 2017

Matthew S Koletsky

3

1 reference

1 September 2017

Francisco Cordero

4

1 reference

1 September 2017

Shu Lin

5

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1 September 2017

Laura A Banaszynski

6

1 reference

1 September 2017

Benjamin A Garcia

7

1 reference

1 September 2017

Tom W Muir

8

1 reference

1 September 2017

Oren J Becher

9

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1 September 2017

language of work or name

English

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publication date

28 March 2013

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1 September 2017

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1 September 2017

340

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1 September 2017

857-861

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1 September 2017

6134

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K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas

1 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951439

Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951439

Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951439

The Polycomb complex PRC2 and its mark in life

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951439

Coordinated activities of wild-type plus mutant EZH2 drive tumor-associated hypertrimethylation of lysine 27 on histone H3 (H3K27) in human B-cell lymphomas

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951439

Binding of different histone marks differentially regulates the activity and specificity of polycomb repressive complex 2 (PRC2)

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951439

Preclinical evaluation of radiation and perifosine in a genetically and histologically accurate model of brainstem glioma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951439

Role of the polycomb protein EED in the propagation of repressive histone marks

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951439

A novel mammalian flavin-dependent histone demethylase

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951439

Roles of the EZH2 histone methyltransferase in cancer epigenetics

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951439

How chromatin-binding modules interpret histone modifications: lessons from professional pocket pickers

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951439

Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951439

New Epigenetic Drivers of Cancers

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951439

3 December 2018

Identifiers

DOI

10.1126/SCIENCE.1232245

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1 September 2017

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1 September 2017

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