(Q38266174)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25380815%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

review article

1 reference

title

SnoN as a novel negative regulator of TGF-β/Smad signaling: a target for tailoring organ fibrosis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25380815%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25380815%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Davinder S Jassal

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25380815%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Ian Dixon

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25380815%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

author name string

Mark Hnatowich

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25380815%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

publication date

7 November 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25380815%20AND%20SRC:MED&resulttype=core&format=json

American Journal of Physiology Heart and Circulatory Physiology

22 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25380815%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

volume

308

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25380815%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25380815%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

page(s)

H75-82

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25380815%20AND%20SRC:MED&resulttype=core&format=json

Mice lacking the ski proto-oncogene have defects in neurulation, craniofacial, patterning, and skeletal muscle development

22 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

Fibrosis in left atrial tissue of patients with atrial fibrillation with and without underlying mitral valve disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

The TGF beta superfamily in myocardium: ligands, receptors, transduction, and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

Transforming growth factor-beta signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

In-frame mutations in exon 1 of SKI cause dominant Shprintzen-Goldberg syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

Docosahexaenoic acid (DHA) ameliorates paraquat-induced pulmonary fibrosis in rats possibly through up-regulation of Smad 7 and SnoN.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

Ski protein levels increase during in vitro progression of HPV16-immortalized human keratinocytes and in cervical cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

Heterodimers of the SnoN and Ski oncoproteins form preferentially over homodimers and are more potent transforming agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

c-Ski, Smurf2, and Arkadia as regulators of TGF-beta signaling: new targets for managing myofibroblast function and cardiac fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

Antifibrotic properties of c-Ski and its regulation of cardiac myofibroblast phenotype and contractility.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

Ski and SnoN, potent negative regulators of TGF-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

Molecular basis of renal fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

MicroRNAs in myocardial infarction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

Therapeutic approaches to organ fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

Liver fibrosis -- from bench to bedside

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

Molecular basis of organ fibrosis: potential therapeutic approaches

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

Requirement of the co-repressor homeodomain-interacting protein kinase 2 for ski-mediated inhibition of bone morphogenetic protein-induced transcriptional activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

The transforming activity of Ski and SnoN is dependent on their ability to repress the activity of Smad proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

Cardiac myofibroblasts: cells out of balance. A new thematic series

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

Sumoylated SnoN represses transcription in a promoter-specific manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

SnoN in mammalian development, function and diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

Expression profiles of SnoN in normal and cancerous human tissues support its tumor suppressor role in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

Transforming growth factor-beta regulator SnoN modulates mammary gland branching morphogenesis, postlactational involution, and mammary tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

Next generation sequencing analysis of miRNAs: MiR-127-3p inhibits glioblastoma proliferation and activates TGF-β signaling by targeting SKI.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

The TGF-beta superfamily: new members, new receptors, and new genetic tests of function in different organisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

Bone marrow progenitor cell therapy-mediated paracrine regulation of cardiac miRNA-155 modulates fibrotic response in diabetic hearts

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

The Ski protein family is required for MeCP2-mediated transcriptional repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

Cytoplasmic SnoN in normal tissues and nonmalignant cells antagonizes TGF-beta signaling by sequestration of the Smad proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

The Ski proto-oncogene regulates body composition and suppresses lipogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

Renal fibrosis: new insights into the pathogenesis and therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

Ski and SnoN: negative regulators of TGF-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

Adenoviral delivery of dominant-negative transforming growth factor beta type II receptor up-regulates transcriptional repressor SKI-like oncogene, decreases matrix metalloproteinase 2 in hepatic stellate cell and prevents liver fibrosis in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

CCR2-mediated recruitment of fibrocytes to the alveolar space after fibrotic injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

Cardiac fibrosis and arrhythmogenesis: the road to repair is paved with perils

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

Isolation of human cDNA clones of ski and the ski-related gene, sno

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

Ski is a component of the histone deacetylase complex required for transcriptional repression by Mad and thyroid hormone receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

SnoN functions as a tumour suppressor by inducing premature senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

21 January 2018

MicroRNAs and fibrosis

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

SnoI, a novel alternatively spliced isoform of the ski protooncogene homolog, sno.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

Proto-oncogene Sno expression, alternative isoforms and immediate early serum response

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

Defective T-cell activation is associated with augmented transforming growth factor Beta sensitivity in mice with mutations in the Sno gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

The SMAD-binding domain of SKI: a hotspot for de novo mutations causing Shprintzen-Goldberg syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

Migration of fibrocytes in fibrogenic liver injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

Loss of MicroRNA-155 protects the heart from pathological cardiac hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

The sno gene, which encodes a component of the histone deacetylase complex, acts as a tumor suppressor in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

Negative feedback regulation of TGF-beta signaling by the SnoN oncoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

SnoN and Ski protooncoproteins are rapidly degraded in response to transforming growth factor beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

dSno facilitates baboon signaling in the Drosophila brain by switching the affinity of Medea away from Mad and toward dSmad2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

20-Hydroxyeicosatetraenoic acid induces apoptosis in neonatal rat cardiomyocytes through mitochondrial-dependent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

Smad ubiquitination regulatory factor-2 in the fibrotic kidney: regulation, target specificity, and functional implication

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

Downregulation of SnoN expression in obstructive nephropathy is mediated by an enhanced ubiquitin-dependent degradation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

Transforming growth factor-β/SMAD Target gene SKIL is negatively regulated by the transcriptional cofactor complex SNON-SMAD4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

The microRNA-15 family inhibits the TGFβ-pathway in the heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

c-Ski activates cancer-associated fibroblasts to regulate breast cancer cell invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

Signal transduction. Feedback from inhibitory SMADs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

Crystal structure of the dachshund homology domain of human SKI

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

Pulmonary fibrosis: pathogenesis, etiology and regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

Regulation of Smad activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

Mechanism of activation of the TGF-beta receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

Transforming growth factor-beta-independent regulation of myogenesis by SnoN sumoylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

Structural mechanism of Smad4 recognition by the nuclear oncoprotein Ski: insights on Ski-mediated repression of TGF-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

DACH1 inhibits transforming growth factor-beta signaling through binding Smad4

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

Mechanisms of fibrosis: therapeutic translation for fibrotic disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

TGF-beta-induced epithelial to mesenchymal transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

A novel mechanism by which hepatocyte growth factor blocks tubular epithelial to mesenchymal transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

Molecular determinants of cardiac fibroblast electrical function and therapeutic implications for atrial fibrillation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

The expression of SnoN in normal human skin and cutaneous keratinous neoplasms

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

Receptor-associated Mad homologues synergize as effectors of the TGF-beta response

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00453.2014

10.1152/AJPHEART.00453.2014

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25380815%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

1 reference