(Q38270705)

1 September 2017

1 reference

title

Endothelial barrier dysfunction in septic shock (English)

1 reference

1 September 2017

0 references

0 references

1 reference

S M Opal

1

1 reference

1 September 2017

T van der Poll

series ordinal

2

1 reference

1 September 2017

language of work or name

English

0 references

publication date

1 March 2015

1 reference

Journal of Internal Medicine

1 September 2017

published in

1 reference

1 September 2017

volume

277

1 reference

1 September 2017

issue

3

1 reference

1 September 2017

page(s)

277-293

1 reference

Determinants of hospital mortality among patients with sepsis or septic shock receiving appropriate antibiotic treatment

1 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Severe sepsis and septic shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

The inflammatory response in sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Sepsis definitions: time for change

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

The next generation of sepsis clinical trial designs: what is next after the demise of recombinant human activated protein C?*.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Sepsis: current dogma and new perspectives

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Immunotherapy for sepsis--a new approach against an ancient foe.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Drotrecogin alfa (activated) in adults with septic shock.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Improved prognosis of septic shock in patients with cirrhosis: a multicenter study*.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

A randomized trial of protocol-based care for early septic shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Neural reflexes in inflammation and immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Association between mitochondrial dysfunction and severity and outcome of septic shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Modulatory mechanisms controlling the NLRP3 inflammasome in inflammation: recent developments

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Sepsis: multiple abnormalities, heterogeneous responses, and evolving understanding

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

How metabolism generates signals during innate immunity and inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Disease tolerance as a defense strategy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

A historical perspective on sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Nonresolving inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

The role of mitochondrial dysfunction in sepsis-induced multi-organ failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

A genomic storm in critically injured humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

HMGB1 is a therapeutic target for sterile inflammation and infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Immunosuppression in patients who die of sepsis and multiple organ failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

The NLRP3 inflammasome: a sensor for metabolic danger?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Bacteria activate sensory neurons that modulate pain and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Splenic nerve is required for cholinergic antiinflammatory pathway control of TNF in endotoxemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Nutrition in the acute phase of critical illness

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Cytochrome c oxidase dysfunction in sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Calcium signaling and mitochondrial destabilization in the triggering of the NLRP3 inflammasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Reactivation of multiple viruses in patients with sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Is boosting the immune system in sepsis appropriate?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

How point-of-care testing could drive innovation in global health

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Targeting Robo4-dependent Slit signaling to survive the cytokine storm in sepsis and influenza

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

The role of the endothelium in severe sepsis and multiple organ dysfunction syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Inflammation, endothelium, and coagulation in sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Endothelial injury in sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Inflammation and coagulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Tissue factor pathway inhibitor reduces mortality from Escherichia coli septic shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Role of tissue factor and protease-activated receptors in a mouse model of endotoxemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Bench-to-bedside review: circulating microparticles--a new player in sepsis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Alternatively spliced tissue factor: a previously unknown piece in the puzzle of hemostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

The tissue factor-factor VIIa complex: procoagulant activity, regulation, and multitasking.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Depletion of extrinsic pathway inhibitor (EPI) sensitizes rabbits to disseminated intravascular coagulation induced with tissue factor: evidence supporting a physiologic role for EPI as a natural anticoagulant

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

The protein C pathway in tissue inflammation and injury: pathogenic role and therapeutic implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Protein C prevents the coagulopathic and lethal effects of Escherichia coli infusion in the baboon

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Thrombotic Microangiopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Systemic infections mimicking thrombotic thrombocytopenic purpura

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

CD40 ligand on activated platelets triggers an inflammatory reaction of endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Engagement of glycoprotein IIb/IIIa (alpha(IIb)beta3) on platelets upregulates CD40L and triggers CD40L-dependent matrix degradation by endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Role of platelet P-selectin and microparticle PSGL-1 in thrombus formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Neutrophil extracellular traps (NETs) and infection-related vascular dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Neutrophil extracellular traps: double-edged swords of innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Thrombosis: tangled up in NETs

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Neutrophil extracellular traps directly induce epithelial and endothelial cell death: a predominant role of histones

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Mechanistic coupling of protease signaling and initiation of coagulation by tissue factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Activation of endothelial cell protease activated receptor 1 by the protein C pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

'Role reversal' for the receptor PAR1 in sepsis-induced vascular damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Activation and inhibition of G protein-coupled receptors by cell-penetrating membrane-tethered peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

A matrix metalloprotease-PAR1 system regulates vascular integrity, systemic inflammation and death in sepsis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Matrix metalloproteases and PAR1 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Noncanonical matrix metalloprotease-1-protease-activated receptor-1 signaling triggers vascular smooth muscle cell dedifferentiation and arterial stenosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Interleukin-1 in the pathogenesis and treatment of inflammatory diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Differential release of chromatin-bound IL-1alpha discriminates between necrotic and apoptotic cell death by the ability to induce sterile inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Cutting edge: critical role for mesothelial cells in necrosis-induced inflammation through the recognition of IL-1 alpha released from dying cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Reciprocal interactions between endothelial cells and macrophages in angiogenic vascular niches.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Excess circulating angiopoietin-2 may contribute to pulmonary vascular leak in sepsis in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

The antiinflammatory endothelial tyrosine kinase Tie2 interacts with a novel nuclear factor-kappaB inhibitor ABIN-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Exosomes--vesicular carriers for intercellular communication

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Endothelial cells provide an instructive niche for the differentiation and functional polarization of M2-like macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Microparticles are novel effectors of immunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Endothelial microparticles induce formation of platelet aggregates via a von Willebrand factor/ristocetin dependent pathway, rendering them resistant to dissociation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Microparticles are new biomarkers of septic shock-induced disseminated intravascular coagulopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Microparticle-associated endothelial protein C receptor and the induction of cytoprotective and anti-inflammatory effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

The clinical and functional relevance of microparticles induced by activated protein C treatment in sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Microcirculatory dysfunction in sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Pathophysiology of microcirculatory dysfunction and the pathogenesis of septic shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Quantitative assessment of the microcirculation in healthy volunteers and in patients with septic shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Microcirculatory alterations in patients with severe sepsis: impact of time of assessment and relationship with outcome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Red blood cell rheology in sepsis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Activated protein C reduces tissue hypoxia, inflammation, and apoptosis in traumatized skeletal muscle during endotoxemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Antithrombin effects on endotoxin-induced microcirculatory disorders are mediated mainly by its interaction with microvascular endothelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Enoxaparin and fondaparinux attenuates endothelial damage in endotoxemic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Emerging therapeutic strategies to prevent infection-related microvascular endothelial activation and dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

VEGF receptor signalling - in control of vascular function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

VEGF controls endothelial-cell permeability by promoting the beta-arrestin-dependent endocytosis of VE-cadherin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Regulation of vascular permeability by sphingosine 1-phosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Endothelial barrier protection by activated protein C through PAR1-dependent sphingosine 1-phosphate receptor-1 crossactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Attenuation of vascular permeability by methylnaltrexone: role of mOP-R and S1P3 transactivation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Concentration dependent dual effect of thrombin in endothelial cells via Par-1 and Pi3 Kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Critical role of sphingosine-1-phosphate receptor 2 (S1PR2) in acute vascular inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Peptide Bbeta(15-42) preserves endothelial barrier function in shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Bbeta15-42 (FX06) reduces pulmonary, myocardial, liver, and small intestine damage in a pig model of hemorrhagic shock and reperfusion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

The fibrinopeptide bβ15-42 reduces inflammation in mice subjected to polymicrobial sepsis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Bbeta(15-42) protects against acid-induced acute lung injury and secondary pseudomonas pneumonia in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Effect of intravenous FX06 as an adjunct to primary percutaneous coronary intervention for acute ST-segment elevation myocardial infarction results of the F.I.R.E. (Efficacy of FX06 in the Prevention of Myocardial Reperfusion Injury) trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Robo4 stabilizes the vascular network by inhibiting pathologic angiogenesis and endothelial hyperpermeability

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Slit2-Robo4 signalling promotes vascular stability by blocking Arf6 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Interleukin receptor activates a MYD88-ARNO-ARF6 cascade to disrupt vascular stability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Biomarkers of endothelial activation/dysfunction in infectious diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Excess circulating angiopoietin-2 is a strong predictor of mortality in critically ill medical patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Angiopoietin-2 may contribute to multiple organ dysfunction and death in sepsis*

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

The synthetic tie2 agonist peptide vasculotide protects against vascular leakage and reduces mortality in murine abdominal sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Effects of a synthetic PEG-ylated Tie-2 agonist peptide on endotoxemic lung injury and mortality

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Angiopoietin-1 variant reduces LPS-induced microvascular dysfunction in a murine model of sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Inflammasome-dependent release of the alarmin HMGB1 in endotoxemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Targeting protease-activated receptor-1 with cell-penetrating pepducins in lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Interdicting protease-activated receptor-2-driven inflammation with cell-penetrating pepducins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Selepressin, a new V1A receptor agonist: hemodynamic comparison to vasopressin in dogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

The harmful role of c5a on innate immunity in sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

A randomized, double-blind, placebo-controlled, Phase 2b study to evaluate the safety and efficacy of recombinant human soluble thrombomodulin, ART-123, in patients with sepsis and suspected disseminated intravascular coagulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Damage- and pathogen-associated molecular patterns and alarmins: keys to sepsis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

HMGB1 induces human lung endothelial cell cytoskeletal rearrangement and barrier disruption

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

HMGB1 increases permeability of the endothelial cell monolayer via RAGE and Src family tyrosine kinase pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Inflammation-promoting activity of HMGB1 on human microvascular endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

IL-1alpha and IL-1beta are endogenous mediators linking cell injury to the adaptive alloimmune response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

The search for effective therapy for sepsis: back to the drawing board?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

Sepsis and Endothelial Permeability

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12331

21 January 2018

Identifiers

DOI

10.1111/JOIM.12331

1 reference

1 September 2017

1 reference