(Q38289137)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7499212%20AND%20SRC:MED&resulttype=core&format=json

19 October 2019

title

TOR mutations confer rapamycin resistance by preventing interaction with FKBP12-rapamycin (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7499212%20AND%20SRC:MED&resulttype=core&format=json

19 October 2019

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7499212%20AND%20SRC:MED&resulttype=core&format=json

19 October 2019

author name string

J Heitman

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7499212%20AND%20SRC:MED&resulttype=core&format=json

19 October 2019

language of work or name

English

0 references

publication date

1 November 1995

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7499212%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

19 October 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7499212%20AND%20SRC:MED&resulttype=core&format=json

19 October 2019

volume

270

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7499212%20AND%20SRC:MED&resulttype=core&format=json

19 October 2019

page(s)

27531-27537

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7499212%20AND%20SRC:MED&resulttype=core&format=json

19 October 2019

issue

46

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7499212%20AND%20SRC:MED&resulttype=core&format=json

The mechanism of action of cyclosporin A and FK506

19 October 2019

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.46.27531

Interleukin-2-mediated elimination of the p27Kip1 cyclin-dependent kinase inhibitor prevented by rapamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.46.27531

Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.46.27531

Rapamycin-induced inhibition of the 70-kilodalton S6 protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.46.27531

A receptor for the immunosuppressant FK506 is a cis-trans peptidyl-prolyl isomerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.46.27531

A cytosolic binding protein for the immunosuppressant FK506 has peptidyl-prolyl isomerase activity but is distinct from cyclophilin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.46.27531

Peptidyl-prolyl cis-trans isomerase is the cyclosporin A-binding protein cyclophilin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.46.27531

Cyclophilin and peptidyl-prolyl cis-trans isomerase are probably identical proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.46.27531

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.46.27531

Two distinct signal transmission pathways in T lymphocytes are inhibited by complexes formed between an immunophilin and either FK506 or rapamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.46.27531

Probing Immunosuppressant Action with a Nonnatural Immunophilin Ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.46.27531

Is cyclophilin involved in the immunosuppressive and nephrotoxic mechanism of action of cyclosporin A?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.46.27531

Targets for Cell Cycle Arrest by the Immunosuppressant Rapamycin in Yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.46.27531

Isolation of the cyclosporin-sensitive T cell transcription factor NFATp

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.46.27531

The T-cell transcription factor NFATp is a substrate for calcineurin and interacts with Fos and Jun

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.46.27531

Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin A

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.46.27531

TOR1 and TOR2 are structurally and functionally similar but not identical phosphatidylinositol kinase homologues in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.46.27531

Target of rapamycin in yeast, TOR2, is an essential phosphatidylinositol kinase homolog required for G1 progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.46.27531

Dominant missense mutations in a novel yeast protein related to mammalian phosphatidylinositol 3-kinase and VPS34 abrogate rapamycin cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.46.27531

A mammalian protein targeted by G1-arresting rapamycin-receptor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.46.27531

RAFT1: a mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.46.27531

Isolation of a protein target of the FKBP12-rapamycin complex in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.46.27531

Identification of an 11-kDa FKBP12-rapamycin-binding domain within the 289-kDa FKBP12-rapamycin-associated protein and characterization of a critical serine residue

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.46.27531

RAPT1, a mammalian homolog of yeast Tor, interacts with the FKBP12/rapamycin complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.46.27531

A ten-minute DNA preparation from yeast efficiently releases autonomous plasmids for transformation of Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.46.27531

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.46.27531

PCR amplification of up to 35-kb DNA with high fidelity and high yield from lambda bacteriophage templates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.46.27531

Site-directed mutagenesis by overlap extension using the polymerase chain reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.46.27531

Yeast TOR (DRR) proteins: amino-acid sequence alignment and identification of structural motifs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.46.27531

FK 506-binding protein proline rotamase is a target for the immunosuppressive agent FK 506 in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.46.27531

Atomic structure of FKBP-FK506, an immunophilin-immunosuppressant complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.46.27531

Atomic structures of the human immunophilin FKBP-12 complexes with FK506 and rapamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.46.27531

Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.46.27531

An essential gene, ESR1, is required for mitotic cell growth, DNA repair and meiotic recombination in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.46.27531

Introducing DNA into Yeast by Transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.46.27531

21 January 2018

Identifiers

DOI

10.1074/JBC.270.46.27531

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7499212%20AND%20SRC:MED&resulttype=core&format=json

19 October 2019

1 reference