(Q38290099)

1 September 2017

title

5'-,3'-inverted thymidine-modified antisense oligodeoxynucleotide targeting midkine. Its design and application for cancer therapy (English)

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1 September 2017

Yoshifumi Takei

1

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1 September 2017

Kenji Kadomatsu

2

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1 September 2017

Hiroshi Itoh

3

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1 September 2017

Waichi Sato

4

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1 September 2017

Kunihiko Nakazawa

5

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1 September 2017

Shunichiro Kubota

6

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1 September 2017

Takashi Muramatsu

7

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1 September 2017

language of work or name

English

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publication date

16 April 2002

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Journal of Biological Chemistry

1 September 2017

published in

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1 September 2017

volume

277

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1 September 2017

issue

26

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1 September 2017

page(s)

23800-23806

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Nucleic acid biotechnology

1 September 2017

cites work

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Antiviral effect of an oligo(nucleoside methylphosphonate) complementary to the splice junction of herpes simplex virus type 1 immediate early pre-mRNAs 4 and 5.

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Design of nuclease resistant protein kinase calpha DNA enzymes with potential therapeutic application.

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Solution structure of midkine, a new heparin-binding growth factor

21 January 2018

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Increased midkine gene expression in human gastrointestinal cancers.

21 January 2018

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Cloning and expression of a developmentally regulated protein that induces mitogenic and neurite outgrowth activity

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Mixed backbone antisense oligonucleotides: design, biochemical and biological properties of oligonucleotides containing 2'-5'-ribo- and 3'-5'-deoxyribonucleotide segments

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Midkine induces the transformation of NIH3T3 cells

21 January 2018

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Antisense RNA to the type I insulin-like growth factor receptor suppresses tumor growth and prevents invasion by rat prostate cancer cells in vivo

21 January 2018

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Pharmacokinetics and tissue distribution in rats of an oligodeoxynucleotide phosphorothioate (GEM 91) developed as a therapeutic agent for human immunodeficiency virus type-1.

21 January 2018

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21 January 2018

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21 January 2018

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Comparison of the toxicity profiles of ISIS 1082 and ISIS 2105, phosphorothioate oligonucleotides, following subacute intradermal administration in Sprague-Dawley rats

21 January 2018

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Evaluation of the toxicity of ISIS 2302, a phosphorothioate oligonucleotide, in a 4-week study in CD-1 mice

21 January 2018

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Antisense therapy in oncology: new hope for an old idea?

21 January 2018

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21 January 2018

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Midkine rescues Wilms' tumor cells from cisplatin-induced apoptosis: regulation of Bcl-2 expression by Midkine

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M112100200

1 reference

1 September 2017

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