(Q38292180)

1 September 2017

Loss of the co-repressor GPS2 sensitizes macrophage activation upon metabolic stress induced by obesity and type 2 diabetes (English)

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1 September 2017

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Saioa Goñi

3

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Rongrong Fan

Rongrong Fan

1

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Fawaz Alzaid

Fawaz Alzaid

6

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Nicolas Venteclef

Nicolas Venteclef

17

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Toby Lawrence

Toby Lawrence

15

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Fabienne Foufelle

Fabienne Foufelle

14

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Anastasios Damdimopoulos

10

Anastasios Damdimopoulos

1 reference

1 September 2017

Judith Aron-Wisnewsky

13

Judith Aron-Wisnewsky

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1 September 2017

18

Eckardt Treuter

1 reference

1 September 2017

Amine Toubal

2

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1 September 2017

Karima Drareni

4

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1 September 2017

Zhiqiang Huang

5

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1 September 2017

Raphaelle Ballaire

7

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1 September 2017

Patricia Ancel

8

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1 September 2017

Ning Liang

9

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1 September 2017

Isabelle Hainault

11

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1 September 2017

Antoine Soprani

12

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1 September 2017

Jean-Francois Gautier

16

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1 September 2017

language of work or name

English

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publication date

6 June 2016

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1 September 2017

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1 September 2017

22

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1 September 2017

7

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1 September 2017

780-791

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https://scigraph.springernature.com/pub.10.1038/nm.4114

1 September 2017

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cites work

Inflammation and lipid signaling in the etiology of insulin resistance

1 reference

Macrophage activation and polarization: nomenclature and experimental guidelines

21 January 2018

1 reference

Defining macrophage phenotype and function in adipose tissue

21 January 2018

1 reference

Irf5 deficiency in macrophages promotes beneficial adipose tissue expansion and insulin sensitivity during obesity.

21 January 2018

1 reference

Metabolic dysfunction drives a mechanistically distinct proinflammatory phenotype in adipose tissue macrophages

21 January 2018

1 reference

Obesity induces a phenotypic switch in adipose tissue macrophage polarization

21 January 2018

1 reference

Adipose tissue macrophages promote myelopoiesis and monocytosis in obesity

21 January 2018

1 reference

Adipose tissue remodeling and obesity

21 January 2018

1 reference

Pathophysiology of human visceral obesity: an update

21 January 2018

1 reference

Obesity activates a program of lysosomal-dependent lipid metabolism in adipose tissue macrophages independently of classic activation

21 January 2018

1 reference

MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity

21 January 2018

1 reference

Signaling by IL-6 promotes alternative activation of macrophages to limit endotoxemia and obesity-associated resistance to insulin

21 January 2018

1 reference

Inflammatory mechanisms in obesity

21 January 2018

1 reference

Epigenomics of macrophages

21 January 2018

1 reference

Inflammation-sensitive super enhancers form domains of coordinately regulated enhancer RNAs

21 January 2018

1 reference

Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription.

21 January 2018

1 reference

Molecular control of activation and priming in macrophages

21 January 2018

1 reference

Transcriptional control of the inflammatory response

21 January 2018

1 reference

Transcriptional regulation of macrophage polarization: enabling diversity with identity

21 January 2018

1 reference

The SMRT and N-CoR corepressors are activating cofactors for histone deacetylase 3

21 January 2018

1 reference

The N-CoR-HDAC3 nuclear receptor corepressor complex inhibits the JNK pathway through the integral subunit GPS2

21 January 2018

1 reference

Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery

21 January 2018

1 reference

The Bcl6-SMRT/NCoR cistrome represses inflammation to attenuate atherosclerosis

21 January 2018

1 reference

Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathways

21 January 2018

1 reference

Nuclear receptor transrepression pathways that regulate inflammation in macrophages and T cells

21 January 2018

1 reference

GPS2-dependent corepressor/SUMO pathways govern anti-inflammatory actions of LRH-1 and LXRbeta in the hepatic acute phase response

21 January 2018

1 reference

SMRT-GPS2 corepressor pathway dysregulation coincides with obesity-linked adipocyte inflammation

21 January 2018

1 reference

A protective strategy against hyperinflammatory responses requiring the nontranscriptional actions of GPS2.

21 January 2018

1 reference

Adipocyte NCoR knockout decreases PPARγ phosphorylation and enhances PPARγ activity and insulin sensitivity

21 January 2018

1 reference

NCoR repression of LXRs restricts macrophage biosynthesis of insulin-sensitizing omega 3 fatty acids

21 January 2018

1 reference

Tissue-resident macrophage enhancer landscapes are shaped by the local microenvironment.

21 January 2018

1 reference

Histone deacetylase 3 is an epigenomic brake in macrophage alternative activation.

21 January 2018

1 reference

Requirement for the histone deacetylase Hdac3 for the inflammatory gene expression program in macrophages

21 January 2018

1 reference

Deacetylase-independent function of HDAC3 in transcription and metabolism requires nuclear receptor corepressor

21 January 2018

1 reference

Insights into negative regulation by the glucocorticoid receptor from genome-wide profiling of inflammatory cistromes

21 January 2018

1 reference

GPS2/KDM4A pioneering activity regulates promoter-specific recruitment of PPARγ.

21 January 2018

1 reference

Identification of nuclear hormone receptor pathways causing insulin resistance by transcriptional and epigenomic analysis.

21 January 2018

1 reference

Genomic and epigenomic regulation of adipose tissue inflammation in obesity

21 January 2018

1 reference

Regulation of RNA polymerase II activation by histone acetylation in single living cells.

21 January 2018

1 reference

LXRs link metabolism to inflammation through Abca1-dependent regulation of membrane composition and TLR signaling

21 January 2018

1 reference

SMRT and N-CoR corepressors are regulated by distinct kinase signaling pathways

21 January 2018

1 reference

Activation of c-Jun N-terminal kinase in bacterial lipopolysaccharide-stimulated macrophages

21 January 2018

1 reference

c-Jun controls histone modifications, NF-kappaB recruitment, and RNA polymerase II function to activate the ccl2 gene

21 January 2018

1 reference

JNK phosphorylation relieves HDAC3-dependent suppression of the transcriptional activity of c-Jun

21 January 2018

1 reference

Silencing mediator of retinoic acid and thyroid hormone receptors, as a novel transcriptional corepressor molecule of activating protein-1, nuclear factor-kappaB, and serum response factor

21 January 2018

1 reference

A nuclear receptor corepressor transcriptional checkpoint controlling activator protein 1-dependent gene networks required for macrophage activation

21 January 2018

1 reference

A high-throughput chromatin immunoprecipitation approach reveals principles of dynamic gene regulation in mammals

21 January 2018

1 reference

Transcription factor cooperativity in early adipogenic hotspots and super-enhancers.

21 January 2018

1 reference

A framework for oligonucleotide microarray preprocessing.

21 January 2018

1 reference

limma powers differential expression analyses for RNA-sequencing and microarray studies

21 January 2018

1 reference

Impaired postnatal hepatocyte proliferation and liver regeneration in mice lacking c-jun in the liver

21 January 2018

1 reference

A lineage of myeloid cells independent of Myb and hematopoietic stem cells

21 January 2018

1 reference

Differential lipid partitioning between adipocytes and tissue macrophages modulates macrophage lipotoxicity and M2/M1 polarization in obese mice

21 January 2018

1 reference

Retinoid X receptor alpha controls innate inflammatory responses through the up-regulation of chemokine expression.

21 January 2018

1 reference

ChIP-seq: using high-throughput sequencing to discover protein-DNA interactions

21 January 2018

1 reference

Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities

21 January 2018

1 reference

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

21 January 2018

1 reference

Differential expression analysis of multifactor RNA-Seq experiments with respect to biological variation

21 January 2018

1 reference

Genome engineering using the CRISPR-Cas9 system

21 January 2018

1 reference

HDL and Glut1 inhibition reverse a hypermetabolic state in mouse models of myeloproliferative disorders.

21 January 2018

1 reference

Fructose uptake in rat adipocytes: GLUT5 expression and the effects of streptozotocin-induced diabetes.

21 January 2018

1 reference

Tumor necrosis factor alpha and regulation of adipose tissue

21 January 2018

1 reference

12 December 2020

Mechanisms Underlying the Selection and Function of Macrophage-Specific Enhancers

1 reference

12 December 2020

Physiology. The health risk of obesity--better metrics imperative

1 reference

12 December 2020

A Clonogenic Bone Marrow Progenitor Specific for Macrophages and Dendritic Cells

1 reference

12 December 2020

A core SMRT corepressor complex containing HDAC3 and TBL1, a WD40-repeat protein linked to deafness

1 reference

12 December 2020

Identifiers

DOI

10.1038/NM.4114

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release_2k4ithdofvg6rflzobvk2h6vc4

1 September 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/2k4ithdofvg6rflzobvk2h6vc4

24 November 2022

mapped directly with Wikidata item

1 reference