(Q38293585)

1 September 2017

title

Antitumor activity- and gene expression-based profiling of ecteinascidin Et 743 and phthalascidin Pt 650. (English)

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1 September 2017

2

E J Corey

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1 September 2017

E J Martinez

1

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1 September 2017

T Owa

series ordinal

3

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1 September 2017

publication date

1 December 2001

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1 September 2017

published in

Chemistry and Biology

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1 September 2017

volume

8

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1 September 2017

issue

12

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1 September 2017

page(s)

1151-1160

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Bioactive compounds from aquatic and terrestrial sources

1 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2801%2900082-5

7 January 2021

Ecteinascidins: Putative Biosynthetic Precursors and Absolute Stereochemistry

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7 January 2021

In vitro antitumor activity of the novel marine agent, ecteinascidin-743 (ET-743, NSC-648766) against human tumors explanted from patients

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https://api.crossref.org/works/10.1016%2FS1074-5521%2801%2900082-5

7 January 2021

High antitumour activity of ET743 against human tumour xenografts from melanoma, non-small-cell lung and ovarian cancer

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https://api.crossref.org/works/10.1016%2FS1074-5521%2801%2900082-5

7 January 2021

Enantioselective Total Synthesis of Ecteinascidin 743

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https://api.crossref.org/works/10.1016%2FS1074-5521%2801%2900082-5

7 January 2021

Phthalascidin, a synthetic antitumor agent with potency and mode of action comparable to ecteinascidin 743.

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https://api.crossref.org/works/10.1016%2FS1074-5521%2801%2900082-5

7 January 2021

Enantioselective synthesis of saframycin A and evaluation of antitumor activity relative to ecteinascidin/saframycin hybrids

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7 January 2021

A New, More Efficient, and Effective Process for the Synthesis of a Key Pentacyclic Intermediate for Production of Ecteinascidin and Phthalascidin Antitumor Agents

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7 January 2021

DNA sequence- and structure-selective alkylation of guanine N2 in the DNA minor groove by ecteinascidin 743, a potent antitumor compound from the Caribbean tunicate Ecteinascidia turbinata

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https://api.crossref.org/works/10.1016%2FS1074-5521%2801%2900082-5

7 January 2021

Ecteinascidin 743: a minor groove alkylator that bends DNA toward the major groove

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7 January 2021

Poisoning of human DNA topoisomerase I by ecteinascidin 743, an anticancer drug that selectively alkylates DNA in the minor groove

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7 January 2021

Ecteinascidin-743 (ET-743), a natural marine compound, with a unique mechanism of action.

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7 January 2021

Unique pattern of ET-743 activity in different cellular systems with defined deficiencies in DNA-repair pathways

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7 January 2021

Ecteinascidin 743, a transcription-targeted chemotherapeutic that inhibits MDR1 activation

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7 January 2021

Interference of transcriptional activation by the antineoplastic drug ecteinascidin-743.

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7 January 2021

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

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7 January 2021

Display and analysis of patterns of differential activity of drugs against human tumor cell lines: development of mean graph and COMPARE algorithm.

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7 January 2021

Identification of a brain- and reproductive-organs-specific gene responsive to DNA damage and retinoic acid

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7 January 2021

Increased DNA Binding Specificity for Antitumor Ecteinascidin 743 through Protein−DNA Interactions?

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7 January 2021

Transcriptional repression of the cystic fibrosis transmembrane conductance regulator gene, mediated by CCAAT displacement protein/cut homolog, is associated with histone deacetylation

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7 January 2021

Regulation of the homeodomain CCAAT displacement/cut protein function by histone acetyltransferases p300/CREB-binding protein (CBP)-associated factor and CBP

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7 January 2021

ATF6 activated by proteolysis binds in the presence of NF-Y (CBF) directly to the cis-acting element responsible for the mammalian unfolded protein response

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https://api.crossref.org/works/10.1016%2FS1074-5521%2801%2900082-5

7 January 2021

Expression monitoring by hybridization to high-density oligonucleotide arrays

1 reference

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7 January 2021

10.1016/S1074-5521(01)00082-5

Identifiers

DOI

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1 September 2017

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