(Q38294677)

1 September 2017

title

HuD, a neuronal-specific RNA-binding protein, increases the in vivo stability of MYCN RNA. (English)

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1 September 2017

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Susan L Cohn

7

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author name string

Chitra F Manohar

1

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1 September 2017

Marc L Short

2

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1 September 2017

Anthony Nguyen

3

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1 September 2017

Nadine N Nguyen

4

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1 September 2017

Daniel Chagnovich

5

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1 September 2017

Qiwei Yang

6

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1 September 2017

language of work or name

English

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publication date

15 November 2001

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Journal of Biological Chemistry

1 September 2017

number of pages

7

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based on heuristic

inferred from page(s)

published in

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1 September 2017

volume

277

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1 September 2017

issue

3

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1 September 2017

page(s)

1967-1973

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Common solid tumors of childhood

1 September 2017

cites work

1 reference

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Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour

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Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage

21 January 2018

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Association between high levels of expression of the TRK gene and favorable outcome in human neuroblastoma

21 January 2018

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N-myc amplification causes down-modulation of MHC class I antigen expression in neuroblastoma

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Episome-generated N-myc antisense RNA restricts the differentiation potential of primitive neuroectodermal cell lines

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Targeted expression of MYCN causes neuroblastoma in transgenic mice

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Binding of a 40-kDa protein to the N-myc 3'-untranslated region correlates with enhanced N-myc expression in human neuroblastoma

21 January 2018

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HuD, a neuronal-specific RNA-binding protein, is a putative regulator of N-myc pre-mRNA processing/stability in malignant human neuroblasts

21 January 2018

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Messenger RNA degradation in eukaryotes

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Nucleotide sequence of the human N-myc gene

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Identification of a common nucleotide sequence in the 3'-untranslated region of mRNA molecules specifying inflammatory mediators

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A conserved AU sequence from the 3' untranslated region of GM-CSF mRNA mediates selective mRNA degradation

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Clinical relevance of minimal residual cancer in patients with solid malignancies

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HuR and mRNA stability

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Overexpression of HuR, a nuclear-cytoplasmic shuttling protein, increases the in vivo stability of ARE-containing mRNAs

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The 3' untranslated region of tumor necrosis factor alpha mRNA is a target of the mRNA-stabilizing factor HuR.

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Control of mRNA decay by heat shock-ubiquitin-proteasome pathway

21 January 2018

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Ectopic expression of Hel-N1, an RNA-binding protein, increases glucose transporter (GLUT1) expression in 3T3-L1 adipocytes

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Identification of HuR as a protein implicated in AUUUA-mediated mRNA decay

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Purification and properties of HuD, a neuronal RNA-binding protein.

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A conserved family of elav-like genes in vertebrates

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HuD, a paraneoplastic encephalomyelitis antigen, contains RNA-binding domains and is homologous to Elav and Sex-lethal

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RNA stabilization by the AU-rich element binding protein, HuR, an ELAV protein

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Hel-N1: an autoimmune RNA-binding protein with specificity for 3' uridylate-rich untranslated regions of growth factor mRNAs

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Selective destabilization of short-lived mRNAs with the granulocyte-macrophage colony-stimulating factor AU-rich 3' noncoding region is mediated by a cotranslational mechanism

21 January 2018

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Selection of a subset of mRNAs from combinatorial 3' untranslated region libraries using neuronal RNA-binding protein Hel-N1

21 January 2018

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The nonamer UUAUUUAUU is the key AU-rich sequence motif that mediates mRNA degradation

21 January 2018

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Four novel U RNAs are encoded by a herpesvirus

21 January 2018

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Interplay of two functionally and structurally distinct domains of the c-fos AU-rich element specifies its mRNA-destabilizing function

21 January 2018

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mRNA decay mediated by two distinct AU-rich elements from c-fos and granulocyte-macrophage colony-stimulating factor transcripts: different deadenylation kinetics and uncoupling from translation

21 January 2018

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Control of c-myc mRNA half-life in vitro by a protein capable of binding to a coding region stability determinant

21 January 2018

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The elav gene product of Drosophila, required in neurons, has three RNP consensus motifs.

21 January 2018

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Cloning and characterization of HuR, a ubiquitously expressed Elav-like protein

21 January 2018

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RNA recognition: towards identifying determinants of specificity

21 January 2018

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The Elav-like proteins bind to AU-rich elements and to the poly(A) tail of mRNA

21 January 2018

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The RNA-binding protein HuD is required for GAP-43 mRNA stability, GAP-43 gene expression, and PKC-dependent neurite outgrowth in PC12 cells.

21 January 2018

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The locus elav of Drosophila melanogaster is expressed in neurons at all developmental stages.

21 January 2018

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Overexpression of HuD accelerates neurite outgrowth and increases GAP-43 mRNA expression in cortical neurons and retinoic acid-induced embryonic stem cells in vitro

21 January 2018

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Paraneoplastic Encephalomyelitis Antigens Bind to the AU-rich Elements of mRNA

21 January 2018

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Differential Activity of ELAV-like RNA-binding Proteins in Human Neuroblastoma

21 January 2018

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Association of multiple copies of the N-myc oncogene with rapid progression of neuroblastomas

21 January 2018

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Activated expression of the N-myc gene in human neuroblastomas and related tumors

21 January 2018

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Prognostic significance of MYCN oncogene expression in childhood neuroblastoma

21 January 2018

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MYCN expression is not prognostic of adverse outcome in advanced-stage neuroblastoma with nonamplified MYCN

21 January 2018

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N-myc oncogene RNA expression in neuroblastoma

21 January 2018

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Clinical relevance of tumor cell ploidy and N-myc gene amplification in childhood neuroblastoma: a Pediatric Oncology Group study

21 January 2018

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Hypoxic stabilization of vascular endothelial growth factor mRNA by the RNA-binding protein HuR

21 January 2018

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The c-fos transcript is targeted for rapid decay by two distinct mRNA degradation pathways

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M106966200

1 reference

1 September 2017

1 reference