(Q38296738)

1 September 2017

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title

Biological and biochemical modulation of DNA methylation (English)

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1 September 2017

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Raymond Lo

1

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1 September 2017

Rosanna Weksberg

series ordinal

2

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1 September 2017

publication date

1 January 2014

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1 September 2017

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1 September 2017

volume

6

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1 September 2017

issue

6

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1 September 2017

page(s)

593-602

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The role of methyl-binding proteins in chromatin organization and epigenome maintenance

1 September 2017

cites work

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Cytosine methylation and the fate of CpG dinucleotides in vertebrate genomes.

21 January 2018

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DNA methylation: past, present and future directions

21 January 2018

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The essentials of DNA methylation

21 January 2018

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DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

21 January 2018

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Recombinant human DNA (cytosine-5) methyltransferase. I. Expression, purification, and comparison of de novo and maintenance methylation

21 January 2018

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DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci

21 January 2018

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Dimerization of DNA methyltransferase 1 is mediated by its regulatory domain

21 January 2018

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CXXC domain of human DNMT1 is essential for enzymatic activity

21 January 2018

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The activity of the murine DNA methyltransferase Dnmt1 is controlled by interaction of the catalytic domain with the N-terminal part of the enzyme leading to an allosteric activation of the enzyme after binding to methylated DNA

21 January 2018

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Interactions within the mammalian DNA methyltransferase family

21 January 2018

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Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

21 January 2018

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Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases

21 January 2018

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Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting

21 January 2018

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Mutations in the DNA methyltransferase gene DNMT3A cause an overgrowth syndrome with intellectual disability.

21 January 2018

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The DNMT3B DNA methyltransferase gene is mutated in the ICF immunodeficiency syndrome

21 January 2018

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Distinct enzymatic properties of recombinant mouse DNA methyltransferases Dnmt3a and Dnmt3b

21 January 2018

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Profound Flanking Sequence Preference of Dnmt3a and Dnmt3b Mammalian DNA Methyltransferases Shape the Human Epigenome

21 January 2018

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Isolation and initial characterization of a novel zinc finger gene, DNMT3L, on 21q22.3, related to the cytosine-5-methyltransferase 3 gene family

21 January 2018

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Reconstitution and mechanism of the stimulation of de novo methylation by human DNMT3L

21 January 2018

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Dnmt3L and the establishment of maternal genomic imprints

21 January 2018

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Dnmt3L antagonizes DNA methylation at bivalent promoters and favors DNA methylation at gene bodies in ESCs

21 January 2018

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DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA

21 January 2018

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Distribution of 5-hydroxymethylcytosine in different human tissues

21 January 2018

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Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine

21 January 2018

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Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1

21 January 2018

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Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells

21 January 2018

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5-Hydroxymethylcytosine is associated with enhancers and gene bodies in human embryonic stem cells

21 January 2018

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Endogenous cytosine damage products alter the site selectivity of human DNA maintenance methyltransferase DNMT1.

21 January 2018

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Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine

21 January 2018

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Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA

21 January 2018

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Excision of 5-hydroxymethyluracil and 5-carboxylcytosine by the thymine DNA glycosylase domain: its structural basis and implications for active DNA demethylation

21 January 2018

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Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification

21 January 2018

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G9a-mediated irreversible epigenetic inactivation of Oct-3/4 during early embryogenesis.

21 January 2018

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De novo DNA methylation promoted by G9a prevents reprogramming of embryonically silenced genes

21 January 2018

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Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer

21 January 2018

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The Polycomb group protein EZH2 directly controls DNA methylation

21 January 2018

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Multilocus loss of DNA methylation in individuals with mutations in the histone H3 lysine 4 demethylase KDM5C.

21 January 2018

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microRNA-199a-3p, DNMT3A, and aberrant DNA methylation in testicular cancer.

21 January 2018

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MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1.

21 January 2018

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MicroRNA-21 and microRNA-148a contribute to DNA hypomethylation in lupus CD4+ T cells by directly and indirectly targeting DNA methyltransferase 1.

21 January 2018

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DNMT1-interacting RNAs block gene-specific DNA methylation

21 January 2018

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DNA methyltransferase inhibitors-state of the art.

21 January 2018

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5-Azacytidine and 5-aza-2'-deoxycytidine as inhibitors of DNA methylation: mechanistic studies and their implications for cancer therapy

21 January 2018

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A decade of exploring the cancer epigenome - biological and translational implications

21 January 2018

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Inhibition of DNA methylation and reactivation of silenced genes by zebularine

21 January 2018

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Synthesis and in vitro evaluation of biotinylated RG108: a high affinity compound for studying binding interactions with human DNA methyltransferases

21 January 2018

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Epigenetic reactivation of tumor suppressor genes by a novel small-molecule inhibitor of human DNA methyltransferases.

21 January 2018

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Psammaplins from the Sponge Pseudoceratina purpurea: Inhibition of Both Histone Deacetylase and DNA Methyltransferase

21 January 2018

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Defining the mechanism of action and enzymatic selectivity of psammaplin A against its epigenetic targets

21 January 2018

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Circulating nucleosomes and response to chemotherapy: an in vitro, in vivo and clinical study on cervical cancer patients

21 January 2018

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Molecular modeling and molecular dynamics studies of hydralazine with human DNA methyltransferase 1.

21 January 2018

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Mechanisms for the inhibition of DNA methyltransferases by tea catechins and bioflavonoids

21 January 2018

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Procainamide is a specific inhibitor of DNA methyltransferase 1.

21 January 2018

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Nanaomycin A Selectively Inhibits DNMT3B and Reactivates Silenced Tumor Suppressor Genes in Human Cancer Cells

21 January 2018

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Key role of ERK pathway signaling in lupus

21 January 2018

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Abnormal epigenetic modifications in peripheral blood mononuclear cells from patients with alopecia areata.

21 January 2018

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Recent advances in the epigenetics and genomics of asthma.

21 January 2018

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Cardiovascular epigenetics: basic concepts and results from animal and human studies

21 January 2018

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The Epstein-Barr virus oncogene product, latent membrane protein 1, induces the downregulation of E-cadherin gene expression via activation of DNA methyltransferases

21 January 2018

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Hepatitis virus infection affects DNA methylation in mice with humanized livers.

21 January 2018

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High levels of aberrant DNA methylation in Helicobacter pylori-infected gastric mucosae and its possible association with gastric cancer risk.

21 January 2018

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Inflammatory processes triggered by Helicobacter pylori infection cause aberrant DNA methylation in gastric epithelial cells

21 January 2018

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Hypomethylation of proximal CpG motif of interleukin-10 promoter regulates its expression in human rheumatoid arthritis

21 January 2018

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Selective, stable demethylation of the interleukin-2 gene enhances transcription by an active process

21 January 2018

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Epigenetic regulation of tumor necrosis factor alpha.

21 January 2018

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Upregulation of DNA methyltransferase-mediated gene silencing, anchorage-independent growth, and migration of colon cancer cells by interleukin-6.

21 January 2018

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The de novo DNA methyltransferase DNMT3A in development and cancer

21 January 2018

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Mutations in DNMT1 cause hereditary sensory neuropathy with dementia and hearing loss

21 January 2018

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Structure and function of the mouse DNA methyltransferase gene: Dnmt1 shows a tripartite structure

21 January 2018

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Hereditary sensory neuropathy with sensorineural deafness and early-onset dementia

21 January 2018

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Mutations in DNMT1 cause autosomal dominant cerebellar ataxia, deafness and narcolepsy

21 January 2018

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Clinical impact of DNMT3A mutations in younger adult patients with acute myeloid leukemia: results of the AML Study Group (AMLSG).

21 January 2018

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Mutant DNMT3A: a marker of poor prognosis in acute myeloid leukemia

21 January 2018

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Clinical spectrum of immunodeficiency, centromeric instability and facial dysmorphism (ICF syndrome)

21 January 2018

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Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2

21 January 2018

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TET2 mutations in acute myeloid leukemia (AML): results from a comprehensive genetic and clinical analysis of the AML study group

21 January 2018

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21 January 2018

Identifiers

DOI

10.2217/EPI.14.49

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1 September 2017

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