(Q38300926)

English

Saposin B mobilizes lipids from cholesterol-poor and bis(monoacylglycero)phosphate-rich membranes at acidic pH. Unglycosylated patient variant saposin B lacks lipid-extraction capacity

scientific article published on 11 June 2007

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Europe PubMed Central

PubMed publication ID

1 September 2017

Saposin B mobilizes lipids from cholesterol-poor and bis(monoacylglycero)phosphate-rich membranes at acidic pH. Unglycosylated patient variant saposin B lacks lipid-extraction capacity (English)

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Europe PubMed Central

PubMed publication ID

1 September 2017

Bernadette Breiden

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Bernadette Breiden

3

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Natascha Remmel

1

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Europe PubMed Central

PubMed publication ID

1 September 2017

Silvia Locatelli-Hoops

2

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Europe PubMed Central

PubMed publication ID

1 September 2017

Guenter Schwarzmann

4

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Europe PubMed Central

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1 September 2017

Konrad Sandhoff

5

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Europe PubMed Central

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1 September 2017

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11 June 2007

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Europe PubMed Central

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1 September 2017

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Europe PubMed Central

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1 September 2017

274

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Europe PubMed Central

PubMed publication ID

1 September 2017

13

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Europe PubMed Central

PubMed publication ID

1 September 2017

3405-3420

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Europe PubMed Central

PubMed publication ID

1 September 2017

Principles of lysosomal membrane digestion: stimulation of sphingolipid degradation by sphingolipid activator proteins and anionic lysosomal lipids

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05873.X

21 January 2018

At the acidic edge: emerging functions for lysosomal membrane proteins

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05873.X

21 January 2018

Biogenesis of lysosomal membranes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05873.X

21 January 2018

Interaction of the GM2-activator protein with phospholipid-ganglioside bilayer membranes and with monolayers at the air-water interface

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05873.X

21 January 2018

Recycling Compartments and the Internal Vesicles of Multivesicular Bodies Harbor Most of the Cholesterol Found in the Endocytic Pathway

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05873.X

21 January 2018

A lipid associated with the antiphospholipid syndrome regulates endosome structure and function

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05873.X

21 January 2018

Glycosphingolipid specificity of the human sulfatide activator protein

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05873.X

21 January 2018

The activator of cerebroside-sulphatase. A model of the activation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05873.X

21 January 2018

The effect of carbohydrate removal on stability and activity of saposin B.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05873.X

21 January 2018

Comparative lipid binding study on the cerebroside sulfate activator (saposin B).

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05873.X

21 January 2018

Saposin B binds and transfers phospholipids

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05873.X

21 January 2018

The enzyme-binding region of human GM2-activator protein

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05873.X

21 January 2018

Editing of CD1d-bound lipid antigens by endosomal lipid transfer proteins.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05873.X

21 January 2018

Lysosomal glycosphingolipid recognition by NKT cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05873.X

21 January 2018

A short guided tour through functional and structural features of saposin-like proteins

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05873.X

21 January 2018

Lipid-binding proteins in membrane digestion, antigen presentation, and antimicrobial defense

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05873.X

21 January 2018

Crystal structure of saposin B reveals a dimeric shell for lipid binding

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05873.X

21 January 2018

Crystal structures of saposins A and C

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05873.X

21 January 2018

A novel mutation in the coding region of the prosaposin gene leads to a complete deficiency of prosaposin and saposins, and is associated with a complex sphingolipidosis dominated by lactosylceramide accumulation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05873.X

21 January 2018

Prosaposin deficiency -- a rarely diagnosed, rapidly progressing, neonatal neurovisceral lipid storage disease. Report of a further patient

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05873.X

21 January 2018

Targeted disruption of the mouse sphingolipid activator protein gene: a complex phenotype, including severe leukodystrophy and wide-spread storage of multiple sphingolipids.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05873.X

21 January 2018

A non-glycosylated and functionally deficient mutant (N215H) of the sphingolipid activator protein B (SAP-B) in a novel case of metachromatic leukodystrophy (MLD).

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05873.X

21 January 2018

The mechanism for a 33-nucleotide insertion in mRNA causing sphingolipid activator protein (SAP-1)-deficient metachromatic leukodystrophy

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05873.X

21 January 2018

Characterization of a mutation in a family with saposin B deficiency: a glycosylation site defect

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05873.X

21 January 2018

Expression of the GM2-activator protein in the methylotrophic yeast Pichia pastoris, purification, isotopic labeling, and biophysical characterization

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05873.X

21 January 2018

Analysis of recombinant human saposin A expressed by Pichia pastoris

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05873.X

21 January 2018

Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05873.X

21 January 2018

Phosphatidylinositol-(4,5)-bisphosphate regulates sorting signal recognition by the clathrin-associated adaptor complex AP2.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05873.X

21 January 2018

A vesicle capture sensor chip for kinetic analysis of interactions with membrane-bound receptors.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05873.X

21 January 2018

Roles of calcium ions in the membrane binding of C2 domains.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05873.X

21 January 2018

Transacylase and phospholipases in the synthesis of bis(monoacylglycero)phosphate

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05873.X

21 January 2018

Sphingolipid activator protein deficiency in a 16-week-old atypical Gaucher disease patient and his fetal sibling: biochemical signs of combined sphingolipidoses

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05873.X

21 January 2018

Direct Visualization of Saposin Remodelling of Lipid Bilayers

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05873.X

21 January 2018

Degradation of membrane-bound ganglioside GM1. Stimulation by bis(monoacylglycero)phosphate and the activator proteins SAP-B and GM2-AP.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05873.X

21 January 2018

Comparison of the cerebroside sulphatase and the arylsulphatase activity of human sulphatase A in the absence of activators

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05873.X

21 January 2018

Sphingolipid activator proteins: proteins with complex functions in lipid degradation and skin biogenesis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05873.X

21 January 2018

Concurrent increase of cholesterol, sphingomyelin and glucosylceramide in the spleen from non-neurologic Niemann-Pick type C patients but also patients possibly affected with other lipid trafficking disorders

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05873.X

21 January 2018

Mechanism of cholesterol transfer from the Niemann-Pick type C2 protein to model membranes supports a role in lysosomal cholesterol transport.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05873.X

21 January 2018

Development of an assay for the intermembrane transfer of cholesterol by Niemann-Pick C2 protein

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05873.X

21 January 2018

Vectors for efficient expression in mammalian fibroblastoid, myeloid and lymphoid cells via transfection or infection.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05873.X

21 January 2018

Measurement of protein using bicinchoninic acid

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05873.X

21 January 2018

Small-volume extrusion apparatus for preparation of large, unilamellar vesicles

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05873.X

21 January 2018

Surface plasmon resonance analysis at a supported lipid monolayer.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05873.X

21 January 2018

Identifiers

10.1111/J.1742-4658.2007.05873.X

1 reference

Europe PubMed Central

PubMed publication ID

1 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 September 2017

ResearchGate publication ID

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