(Q38301313)

1 September 2017

title

Mutations of the HIPK2 gene in acute myeloid leukemia and myelodysplastic syndrome impair AML1- and p53-mediated transcription (English)

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1 September 2017

main subject

myelodysplastic syndrome

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inferred from title

acute myeloid leukemia

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Li XL

1

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1 September 2017

Arai Y

2

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1 September 2017

Harada H

3

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1 September 2017

Shima Y

4

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1 September 2017

Yoshida H

5

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1 September 2017

Rokudai S

6

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1 September 2017

Aikawa Y

7

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1 September 2017

Kimura A

8

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1 September 2017

Kitabayashi I

9

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1 September 2017

language of work or name

English

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publication date

28 May 2007

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1 September 2017

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1 September 2017

volume

26

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1 September 2017

issue

51

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1 September 2017

page(s)

7231-7239

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1210523

1 September 2017

exact match

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cites work

Identification of AML-1 and the (8;21) translocation protein (AML-1/ETO) as sequence-specific DNA-binding proteins: the runt homology domain is required for DNA binding and protein-protein interactions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210523

Isolation and characterization of cDNAs for the protein kinase HIPK2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210523

Roles of HIPK1 and HIPK2 in AML1- and p300-dependent transcription, hematopoiesis and blood vessel formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210523

7 January 2021

The translocation t(8;16)(p11;p13) of acute myeloid leukaemia fuses a putative acetyltransferase to the CREB-binding protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210523

7 January 2021

Consistent fusion of MOZ and TIF2 in AML with inv(8)(p11q13).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210523

7 January 2021

MOZ is fused to p300 in an acute monocytic leukemia with t(8;22).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210523

7 January 2021

The homeodomain protein NK-3 recruits Groucho and a histone deacetylase complex to repress transcription

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210523

7 January 2021

Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210523

7 January 2021

The PML-RARα fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210523

7 January 2021

Identification of a retinoic acid responsive element in the retinoic acid receptor beta gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210523

7 January 2021

The homeodomain-interacting kinase PKM (HIPK-2) modifies ND10 through both its kinase domain and a SUMO-1 interaction motif and alters the posttranslational modification of PML.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210523

7 January 2021

Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210523

7 January 2021

High incidence of somatic mutations in the AML1/RUNX1 gene in myelodysplastic syndrome and low blast percentage myeloid leukemia with myelodysplasia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210523

7 January 2021

Regulation of homeodomain-interacting protein kinase 2 (HIPK2) effector function through dynamic small ubiquitin-related modifier-1 (SUMO-1) modification

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210523

7 January 2021

Human homeodomain-interacting protein kinase-2 (HIPK2) is a member of the DYRK family of protein kinases and maps to chromosome 7q32-q34.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210523

7 January 2021

Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210523

7 January 2021

Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210523

7 January 2021

Identification of three major sentrinization sites in PML

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210523

7 January 2021

Covalent modification of the homeodomain-interacting protein kinase 2 (HIPK2) by the ubiquitin-like protein SUMO-1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210523

7 January 2021

Homeodomain-interacting protein kinases, a novel family of co-repressors for homeodomain transcription factors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210523

7 January 2021

Desumoylation of homeodomain-interacting protein kinase 2 (HIPK2) through the cytoplasmic-nuclear shuttling of the SUMO-specific protease SENP1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210523

7 January 2021

Activation of AML1-mediated transcription by MOZ and inhibition by the MOZ-CBP fusion protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210523

7 January 2021

Fusion of MOZ and p300 histone acetyltransferases in acute monocytic leukemia with a t(8;22)(p11;q13) chromosome translocation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210523

7 January 2021

Interaction and functional cooperation of the leukemia-associated factors AML1 and p300 in myeloid cell differentiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210523

7 January 2021

Tumor suppressor genes in normal and malignant hematopoiesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210523

7 January 2021

Opposed regulation of corepressor CtBP by SUMOylation and PDZ binding.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210523

7 January 2021

A small ubiquitin-related polypeptide involved in targeting RanGAP1 to nuclear pore complex protein RanBP2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210523

7 January 2021

A novel ubiquitin-like modification modulates the partitioning of the Ran-GTPase-activating protein RanGAP1 between the cytosol and the nuclear pore complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210523

7 January 2021

SUMO-1 modification and its role in targeting the Ran GTPase-activating protein, RanGAP1, to the nuclear pore complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210523

7 January 2021

Generation of the AML1-EVI-1 fusion gene in the t(3;21)(q26;q22) causes blastic crisis in chronic myelocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210523

7 January 2021

A breakpoint map of recurrent chromosomal rearrangements in human neoplasia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210523

7 January 2021

t(8;21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene, AML1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210523

7 January 2021

Sp100 is important for the stimulatory effect of homeodomain-interacting protein kinase-2 on p53-dependent gene expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210523

7 January 2021

Physical and functional link of the leukemia-associated factors AML1 and PML.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210523

7 January 2021

The 3;21 translocation in myelodysplasia results in a fusion transcript between the AML1 gene and the gene for EAP, a highly conserved protein associated with the Epstein-Barr virus small RNA EBER 1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210523

7 January 2021

PEBP2/PEA2 represents a family of transcription factors homologous to the products of the Drosophila runt gene and the human AML1 gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210523

7 January 2021

AML1(-/-) embryos do not express certain hematopoiesis-related gene transcripts including those of the PU.1 gene.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210523

7 January 2021

AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210523

7 January 2021

High mobility group I (Y) proteins bind HIPK2, a serine-threonine kinase protein which inhibits cell growth

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210523

7 January 2021

Axin stimulates p53 functions by activation of HIPK2 kinase through multimeric complex formation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210523

7 January 2021

Absence of fetal liver hematopoiesis in mice deficient in transcriptional coactivator core binding factor beta

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210523

7 January 2021

MLL is fused to CBP, a histone acetyltransferase, in therapy-related acute myeloid leukemia with a t(11;16)(q23;p13.3).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210523

7 January 2021

Differential interactions of the homeodomain-interacting protein kinase 2 (HIPK2) by phosphorylation-dependent sumoylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210523

7 January 2021

TP53INP1s and homeodomain-interacting protein kinase-2 (HIPK2) are partners in regulating p53 activity.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210523

7 January 2021

Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210523

7 January 2021

The CBFbeta subunit is essential for CBFalpha2 (AML1) function in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210523

7 January 2021

Interaction of Brn3a and HIPK2 mediates transcriptional repression of sensory neuron survival

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210523

7 January 2021

Homeodomain-interacting protein kinase-2 mediates CtBP phosphorylation and degradation in UV-triggered apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210523

7 January 2021

Homeodomain interacting protein kinase 2 promotes apoptosis by downregulating the transcriptional corepressor CtBP.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210523

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1210523

1 reference

Dimensions Publication ID

1 September 2017

1004547979

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1 reference