(Q38309820)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25565353%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

review article

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title

Genetic control of midbrain dopaminergic neuron development (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25565353%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

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1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25565353%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

author name string

Siew-Lan Ang

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25565353%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

publication date

6 January 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25565353%20AND%20SRC:MED&resulttype=core&format=json

Wiley interdisciplinary reviews. Developmental biology

27 February 2020

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25565353%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

volume

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25565353%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

issue

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25565353%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

page(s)

113-134

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25565353%20AND%20SRC:MED&resulttype=core&format=json

The functional anatomy of basal ganglia disorders

27 February 2020

cites work

1 reference

Genes, dopamine and cortical signal-to-noise ratio in schizophrenia

21 January 2018

1 reference

The persistence of maladaptive memory: addiction, drug memories and anti-relapse treatments

21 January 2018

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Dopamine neurons modulate neural encoding and expression of depression-related behaviour

21 January 2018

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Dopamine neuron systems in the brain: an update

21 January 2018

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Dopamine reward circuitry: two projection systems from the ventral midbrain to the nucleus accumbens-olfactory tubercle complex.

21 January 2018

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Dissecting the diversity of midbrain dopamine neurons.

21 January 2018

1 reference

Getting connected in the dopamine system.

21 January 2018

1 reference

Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible form of Cre recombinase

21 January 2018

1 reference

Changing requirements for Gbx2 in development of the cerebellum and maintenance of the mid/hindbrain organizer.

21 January 2018

1 reference

Evidence for an expansion-based temporal Shh gradient in specifying vertebrate digit identities

21 January 2018

1 reference

Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety

21 January 2018

1 reference

Multiple roles of beta-catenin in controlling the neurogenic niche for midbrain dopamine neurons.

21 January 2018

1 reference

Transgenic expression of Cre recombinase from the tyrosine hydroxylase locus

21 January 2018

1 reference

Characterization of a mouse strain expressing Cre recombinase from the 3' untranslated region of the dopamine transporter locus.

21 January 2018

1 reference

Progressive parkinsonism in mice with respiratory-chain-deficient dopamine neurons

21 January 2018

1 reference

Ontogeny of tyrosine hydroxylase mRNA expression in mid- and forebrain: neuromeric pattern and novel positive regions.

21 January 2018

1 reference

Developmental origin and fate of meso-diencephalic dopamine neurons

21 January 2018

1 reference

The floor plate: multiple cells, multiple signals

21 January 2018

1 reference

Fate of mesencephalic AHD2-expressing dopamine progenitor cells in NURR1 mutant mice

21 January 2018

1 reference

Identification of intrinsic determinants of midbrain dopamine neurons

21 January 2018

1 reference

Differences in neurogenic potential in floor plate cells along an anteroposterior location: midbrain dopaminergic neurons originate from mesencephalic floor plate cells

21 January 2018

1 reference

Morphogen to mitogen: the multiple roles of hedgehog signalling in vertebrate neural development

21 January 2018

1 reference

Spatiotemporally separable Shh domains in the midbrain define distinct dopaminergic progenitor pools

21 January 2018

1 reference

Temporal-spatial changes in Sonic Hedgehog expression and signaling reveal different potentials of ventral mesencephalic progenitors to populate distinct ventral midbrain nuclei

21 January 2018

1 reference

Timing of Sonic hedgehog and Gli1 expression segregates midbrain dopamine neurons

21 January 2018

1 reference

Identification of midbrain floor plate radial glia-like cells as dopaminergic progenitors

21 January 2018

1 reference

Development. The decade of the developing brain

21 January 2018

1 reference

Conserved biological function between Pax-2 and Pax-5 in midbrain and cerebellum development: evidence from targeted mutations

21 January 2018

1 reference

Midbrain dopaminergic neurons: control of their cell fate by the engrailed transcription factors

21 January 2018

1 reference

Early anterior/posterior patterning of the midbrain and cerebellum

21 January 2018

1 reference

An Fgf8 mutant allelic series generated by Cre- and Flp-mediated recombination

21 January 2018

1 reference

FGF and Shh signals control dopaminergic and serotonergic cell fate in the anterior neural plate

21 January 2018

1 reference

The isthmic organizer signal FGF8 is required for cell survival in the prospective midbrain and cerebellum.

21 January 2018

1 reference

Cell behaviors and genetic lineages of the mesencephalon and rhombomere 1.

21 January 2018

1 reference

A Wnt1-regulated genetic network controls the identity and fate of midbrain-dopaminergic progenitors in vivo

21 January 2018

1 reference

Genetic dissection of midbrain dopamine neuron development in vivo

21 January 2018

1 reference

Wnt5a cooperates with canonical Wnts to generate midbrain dopaminergic neurons in vivo and in stem cells

21 January 2018

1 reference

Classical embryological studies and modern genetic analysis of midbrain and cerebellum development

21 January 2018

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Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function

21 January 2018

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Sonic hedgehog regulates Gli activator and repressor functions with spatial and temporal precision in the mid/hindbrain region

21 January 2018

1 reference

Signals from the ventral midline and isthmus regulate the development of Brn3.0-expressing neurons in the midbrain

21 January 2018

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Ventral specification and perturbed boundary formation in the mouse midbrain in the absence of Hedgehog signaling

21 January 2018

1 reference

Foxa1 and Foxa2 positively and negatively regulate Shh signalling to specify ventral midbrain progenitor identity.

21 January 2018

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Genome-wide characterization of Foxa2 targets reveals upregulation of floor plate genes and repression of ventrolateral genes in midbrain dopaminergic progenitors

21 January 2018

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Specification of dopaminergic subsets involves interplay of En1 and Pitx3

21 January 2018

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Foxa1 and Foxa2 regulate multiple phases of midbrain dopaminergic neuron development in a dosage-dependent manner

21 January 2018

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Foxa1 and Foxa2 function both upstream of and cooperatively with Lmx1a and Lmx1b in a feedforward loop promoting mesodiencephalic dopaminergic neuron development

21 January 2018

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Lmx1a and Lmx1b cooperate with Foxa2 to coordinate the specification of dopaminergic neurons and control of floor plate cell differentiation in the developing mesencephalon

21 January 2018

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Lmx1a and lmx1b function cooperatively to regulate proliferation, specification, and differentiation of midbrain dopaminergic progenitors.

21 January 2018

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Specific and integrated roles of Lmx1a, Lmx1b and Phox2a in ventral midbrain development

21 January 2018

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The basic helix-loop-helix transcription factor Nato3 controls neurogenic activity in mesencephalic floor plate cells

21 January 2018

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Neurogenin 2 is required for the development of ventral midbrain dopaminergic neurons

21 January 2018

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Development of the mesencephalic dopaminergic neuron system is compromised in the absence of neurogenin 2

21 January 2018

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Nurr1 is essential for the induction of the dopaminergic phenotype and the survival of ventral mesencephalic late dopaminergic precursor neurons

21 January 2018

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Dopamine neuron agenesis in Nurr1-deficient mice

21 January 2018

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Dopamine biosynthesis is selectively abolished in substantia nigra/ventral tegmental area but not in hypothalamic neurons in mice with targeted disruption of the Nurr1 gene

21 January 2018

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Involvement of Nurr1 in specifying the neurotransmitter identity of ventral midbrain dopaminergic neurons

21 January 2018

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Nurr1 is required for maintenance of maturing and adult midbrain dopamine neurons

21 January 2018

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Anterior-posterior graded response to Otx2 controls proliferation and differentiation of dopaminergic progenitors in the ventral mesencephalon

21 January 2018

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Otx2 regulates subtype specification and neurogenesis in the midbrain

21 January 2018

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Otx2 controls neuron subtype identity in ventral tegmental area and antagonizes vulnerability to MPTP.

21 January 2018

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Pitx3 regulates tyrosine hydroxylase expression in the substantia nigra and identifies a subgroup of mesencephalic dopaminergic progenitor neurons during mouse development

21 January 2018

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Pitx3 is required for development of substantia nigra dopaminergic neurons.

21 January 2018

1 reference

Early developmental failure of substantia nigra dopamine neurons in mice lacking the homeodomain gene Pitx3

21 January 2018

1 reference

Cell-autonomous FGF signaling regulates anteroposterior patterning and neuronal differentiation in the mesodiencephalic dopaminergic progenitor domain.

21 January 2018

1 reference

Fibroblast growth factor receptors cooperate to regulate neural progenitor properties in the developing midbrain and hindbrain

21 January 2018

1 reference

Liver X receptors and oxysterols promote ventral midbrain neurogenesis in vivo and in human embryonic stem cells

21 January 2018

1 reference

Shh dependent and independent maintenance of basal midbrain

21 January 2018

1 reference

Wnt antagonism of Shh facilitates midbrain floor plate neurogenesis

21 January 2018

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Temporal and spatial requirements of Smoothened in ventral midbrain neuronal development

21 January 2018

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Duration of Shh signaling contributes to mDA neuron diversity

21 January 2018

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Dynamic temporal requirement of Wnt1 in midbrain dopamine neuron development

21 January 2018

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Wnt2 regulates progenitor proliferation in the developing ventral midbrain

21 January 2018

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Wnt5a regulates ventral midbrain morphogenesis and the development of A9-A10 dopaminergic cells in vivo

21 January 2018

1 reference

Ectopic Wnt/beta-catenin signaling induces neurogenesis in the spinal cord and hindbrain floor plate

21 January 2018

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Interactions of Wnt/beta-catenin signaling and sonic hedgehog regulate the neurogenesis of ventral midbrain dopamine neurons

21 January 2018

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A second independent pathway for development of mesencephalic dopaminergic neurons requires Lmx1b.

21 January 2018

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An Lmx1b-miR135a2 regulatory circuit modulates Wnt1/Wnt signaling and determines the size of the midbrain dopaminergic progenitor pool

21 January 2018

1 reference

Lmx1b is essential for Fgf8 and Wnt1 expression in the isthmic organizer during tectum and cerebellum development in mice

21 January 2018

1 reference

Otx2 regulates the extent, identity and fate of neuronal progenitor domains in the ventral midbrain

21 January 2018

1 reference

Doublesex and mab-3-related transcription factor 5 promotes midbrain dopaminergic identity in pluripotent stem cells by enforcing a ventral-medial progenitor fate

21 January 2018

1 reference

Wnt1-lmx1a forms a novel autoregulatory loop and controls midbrain dopaminergic differentiation synergistically with the SHH-FoxA2 pathway

21 January 2018

1 reference

FGF signaling gradient maintains symmetrical proliferative divisions of midbrain neuronal progenitors

21 January 2018

1 reference

Brain endogenous liver X receptor ligands selectively promote midbrain neurogenesis

21 January 2018

1 reference

Orphan nuclear receptor Nurr1 directly transactivates the promoter activity of the tyrosine hydroxylase gene in a cell-specific manner

21 January 2018

1 reference

Pitx3 potentiates Nurr1 in dopamine neuron terminal differentiation through release of SMRT-mediated repression

21 January 2018

1 reference

Identification of Dlk1, Ptpru and Klhl1 as novel Nurr1 target genes in meso-diencephalic dopamine neurons

21 January 2018

1 reference

Direct regulation of Pitx3 expression by Nurr1 in culture and in developing mouse midbrain

21 January 2018

1 reference

Foxa2 acts as a co-activator potentiating expression of the Nurr1-induced DA phenotype via epigenetic regulation

21 January 2018

1 reference

A homeodomain gene Ptx3 has highly restricted brain expression in mesencephalic dopaminergic neurons

21 January 2018

1 reference

The transcription factor Pitx3 is expressed selectively in midbrain dopaminergic neurons susceptible to neurodegenerative stress

21 January 2018

1 reference

Retinoic acid counteracts developmental defects in the substantia nigra caused by Pitx3 deficiency.

21 January 2018

1 reference

Retinoic acid-dependent and -independent gene-regulatory pathways of Pitx3 in meso-diencephalic dopaminergic neurons

21 January 2018

1 reference

Engrailed genes are cell-autonomously required to prevent apoptosis in mesencephalic dopaminergic neurons

21 January 2018

1 reference

Otx2 expression is restricted to dopaminergic neurons of the ventral tegmental area in the adult brain

21 January 2018

1 reference

Otx2 selectively controls the neurogenesis of specific neuronal subtypes of the ventral tegmental area and compensates En1-dependent neuronal loss and MPTP vulnerability

21 January 2018

1 reference

The transcription factor orthodenticle homeobox 2 influences axonal projections and vulnerability of midbrain dopaminergic neurons.

21 January 2018

1 reference

Histogenesis of the substantia nigra, ventral tegmental area of Tsai and interpeduncular nucleus: An autoradiographic study of the mesencephalon in the rat

21 January 2018

1 reference

Migration of dopaminergic neurons in the embryonic mesencephalon of mice

21 January 2018

1 reference

Reelin and CXCL12 regulate distinct migratory behaviors during the development of the dopaminergic system.

21 January 2018

1 reference

Cxcl12/Cxcr4 signaling controls the migration and process orientation of A9-A10 dopaminergic neurons.

21 January 2018

1 reference

CXC chemokine receptor 4 regulates neuronal migration and axonal pathfinding in the developing nervous system: implications for neuronal regeneration in the adult brain

21 January 2018

1 reference

Coordinate expression of L1 and 6B4 proteoglycan/phosphacan is correlated with the migration of mesencephalic dopaminergic neurons in mice

21 January 2018

1 reference

Altered distribution of dopaminergic neurons in the brain of L1 null mice

21 January 2018

1 reference

Go or stop? Divergent roles of Reelin in radial neuronal migration

21 January 2018

1 reference

Lack of Reelin causes malpositioning of nigral dopaminergic neurons: Evidence from comparison of normal and Relnrl mutant mice

21 January 2018

1 reference

Migratory defect of mesencephalic dopaminergic neurons in developing reeler mice

21 January 2018

1 reference

ApoER2 and VLDLr are required for mediating reelin signalling pathway for normal migration and positioning of mesencephalic dopaminergic neurons

21 January 2018

1 reference

Towards stem cell replacement therapies for Parkinson's disease

21 January 2018

1 reference

Sox6 and Otx2 control the specification of substantia nigra and ventral tegmental area dopamine neurons.

21 January 2018

1 reference

Defining midbrain dopaminergic neuron diversity by single-cell gene expression profiling.

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/WDEV.169

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25565353%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

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