(Q42832693)

8 November 2017

Otx2 controls neuron subtype identity in ventral tegmental area and antagonizes vulnerability to MPTP. (English)

1 reference

8 November 2017

Michela Di Salvio

1

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Antonio Simeone

object named as

Antonio Simeone

8

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W. Wurst

7

object named as

Wolfgang Wurst

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8 November 2017

Nilima Prakash

6

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ORCID Public Data File 2021

author name string

Luca Giovanni Di Giovannantonio

2

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8 November 2017

Dario Acampora

3

1 reference

8 November 2017

Raffaele Prosperi

4

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8 November 2017

Daniela Omodei

5

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8 November 2017

language of work or name

English

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publication date

7 November 2010

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8 November 2017

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8 November 2017

13

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8 November 2017

1481-1488

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8 November 2017

12

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https://scigraph.springernature.com/pub.10.1038/nn.2661

8 November 2017

0 references

cites work

How to make a mesodiencephalic dopaminergic neuron

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Ontogeny of tyrosine hydroxylase mRNA expression in mid- and forebrain: neuromeric pattern and novel positive regions.

21 January 2018

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Anterior-posterior graded response to Otx2 controls proliferation and differentiation of dopaminergic progenitors in the ventral mesencephalon

21 January 2018

1 reference

Identification of dopaminergic neurons of nigral and ventral tegmental area subtypes in grafts of fetal ventral mesencephalon based on cell morphology, protein expression, and efferent projections.

21 January 2018

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Development of dopaminergic neurons in the mammalian brain

21 January 2018

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Genetic control of dopaminergic neuron differentiation

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Nurr1 is essential for the induction of the dopaminergic phenotype and the survival of ventral mesencephalic late dopaminergic precursor neurons

21 January 2018

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The role of Nurr1 in the development of dopaminergic neurons and Parkinson's disease

21 January 2018

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A second independent pathway for development of mesencephalic dopaminergic neurons requires Lmx1b.

21 January 2018

1 reference

Early developmental failure of substantia nigra dopamine neurons in mice lacking the homeodomain gene Pitx3

21 January 2018

1 reference

Neurogenin 2 is required for the development of ventral midbrain dopaminergic neurons

21 January 2018

1 reference

Foxa1 and Foxa2 regulate multiple phases of midbrain dopaminergic neuron development in a dosage-dependent manner

21 January 2018

1 reference

Development of the mesencephalic dopaminergic neuron system is compromised in the absence of neurogenin 2

21 January 2018

1 reference

Identification of intrinsic determinants of midbrain dopamine neurons

21 January 2018

1 reference

Differences in neurogenic potential in floor plate cells along an anteroposterior location: midbrain dopaminergic neurons originate from mesencephalic floor plate cells

21 January 2018

1 reference

Pitx3 is required for motor activity and for survival of a subset of midbrain dopaminergic neurons

21 January 2018

1 reference

Pitx3 is required for development of substantia nigra dopaminergic neurons.

21 January 2018

1 reference

Progressive loss of dopaminergic neurons in the ventral midbrain of adult mice heterozygote for Engrailed1

21 January 2018

1 reference

Slow progressive degeneration of nigral dopaminergic neurons in postnatal Engrailed mutant mice

21 January 2018

1 reference

Dopamine neuron agenesis in Nurr1-deficient mice

21 January 2018

1 reference

Differential regulation of midbrain dopaminergic neuron development by Wnt-1, Wnt-3a, and Wnt-5a

21 January 2018

1 reference

Otx dose-dependent integrated control of antero-posterior and dorso-ventral patterning of midbrain

21 January 2018

1 reference

Otx2 regulates the extent, identity and fate of neuronal progenitor domains in the ventral midbrain

21 January 2018

1 reference

A Wnt1-regulated genetic network controls the identity and fate of midbrain-dopaminergic progenitors in vivo

21 January 2018

1 reference

Dopamine transporter glycosylation correlates with the vulnerability of midbrain dopaminergic cells in Parkinson's disease.

21 January 2018

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Parkinson's disease: mechanisms and models

21 January 2018

1 reference

Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: contribution to the apoptotic theory in Parkinson's disease

21 January 2018

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Cell type-specific gene expression of midbrain dopaminergic neurons reveals molecules involved in their vulnerability and protection

21 January 2018

1 reference

Gene expression profiling of rat midbrain dopamine neurons: implications for selective vulnerability in parkinsonism

21 January 2018

1 reference

An immunocytochemical study on the distribution of two G-protein-gated inward rectifier potassium channels (GIRK2 and GIRK4) in the adult rat brain.

21 January 2018

1 reference

Girk2 expression in the ventral midbrain, cerebellum, and olfactory bulb and its relationship to the murine mutation weaver.

21 January 2018

1 reference

Otx2 expression is restricted to dopaminergic neurons of the ventral tegmental area in the adult brain

21 January 2018

1 reference

Midbrain dopaminergic neurons in the mouse that contain calbindin-D28k exhibit reduced vulnerability to MPTP-induced neurodegeneration

21 January 2018

1 reference

Characterization of a mouse strain expressing Cre recombinase from the 3' untranslated region of the dopamine transporter locus.

21 January 2018

1 reference

Selective inactivation of Otx2 mRNA isoforms reveals isoform-specific requirement for visceral endoderm anteriorization and head morphogenesis and highlights cell diversity in the visceral endoderm.

21 January 2018

1 reference

The foxa2 gene controls the birth and spontaneous degeneration of dopamine neurons in old age

21 January 2018

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The role of N-glycosylation in function and surface trafficking of the human dopamine transporter

21 January 2018

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Oligomerization and trafficking of the human dopamine transporter. Mutational analysis identifies critical domains important for the functional expression of the transporter

21 January 2018

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Absence of MPTP-induced neuronal death in mice lacking the dopamine transporter.

21 January 2018

1 reference

Meis2 competes with the Groucho co-repressor Tle4 for binding to Otx2 and specifies tectal fate without induction of a secondary midbrain-hindbrain boundary organizer.

21 January 2018

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Nurr1 is required for maintenance of maturing and adult midbrain dopamine neurons

21 January 2018

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Generalized lacZ expression with the ROSA26 Cre reporter strain

21 January 2018

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The pathology of Parkinson's disease

21 January 2018

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12 December 2020

Dopamine transporter expression confers cytotoxicity to low doses of the parkinsonism-inducing neurotoxin 1-methyl-4-phenylpyridinium.

1 reference

12 December 2020

Time course and morphology of dopaminergic neuronal death caused by the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

1 reference

12 December 2020

Cell death in the midbrain of the murine mutation weaver.

1 reference

12 December 2020

EVIDENCE FOR THE EXISTENCE OF MONOAMINE-CONTAINING NEURONS IN THE CENTRAL NERVOUS SYSTEM. I. DEMONSTRATION OF MONOAMINES IN THE CELL BODIES OF BRAIN STEM NEURONS

1 reference

12 December 2020

Fate of midbrain dopaminergic neurons controlled by the engrailed genes

1 reference

12 December 2020

Regulation of dopamine cell type and transmitter function in fetal and stem cell transplantation for Parkinson's disease.

1 reference

12 December 2020

Identifiers

DOI

10.1038/NN.2661

1 reference

Dimensions Publication ID

8 November 2017

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1 reference