(Q38314756)

2 September 2017

1 reference

title

The multifaceted factor peroxisome proliferator-activated receptor γ (PPARγ) in metabolism, immunity, and cancer (English)

1 reference

2 September 2017

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25579849%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Kye Won Park

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25579849%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

author name string

Jung-Hoon Kim

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25579849%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

publication date

13 January 2015

1 reference

Archives of Pharmacal Research

2 September 2017

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25579849%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

volume

38

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25579849%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25579849%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

page(s)

302-312

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25579849%20AND%20SRC:MED&resulttype=core&format=json

PPAR-gamma agonists inhibit toll-like receptor-mediated activation of dendritic cells via the MAP kinase and NF-kappaB pathways

13 June 2020

cites work

1 reference

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Critical role of c-Jun N-terminal protein kinase activation in troglitazone-induced apoptosis of human HepG2 hepatoma cells

21 January 2018

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Selective modulators of PPAR activity as new therapeutic tools in metabolic diseases.

21 January 2018

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PPAR gamma is required for placental, cardiac, and adipose tissue development

21 January 2018

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Adipose tissue browning and metabolic health

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Elevated NCOR1 disrupts PPARalpha/gamma signaling in prostate cancer and forms a targetable epigenetic lesion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Peroxisome proliferator-activated receptor-gamma activates p53 gene promoter binding to the nuclear factor-kappaB sequence in human MCF7 breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Antitumorigenic effects of peroxisome proliferator-activated receptor-gamma in non-small-cell lung cancer cells are mediated by suppression of cyclooxygenase-2 via inhibition of nuclear factor-kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

A Role for the PPARgamma in Cancer Therapy.

21 January 2018

1 reference

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Differentiation and growth inhibition mediated via the RXR:PPARgamma heterodimer in colon cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

A PPAR gamma-LXR-ABCA1 pathway in macrophages is involved in cholesterol efflux and atherogenesis

21 January 2018

1 reference

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Ciglitazone-induced cellular anti-proliferation increases p27kip1 protein levels through both increased transcriptional activity and inhibition of proteasome degradation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARgamma by Cdk5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Antidiabetic actions of a non-agonist PPARγ ligand blocking Cdk5-mediated phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Forming functional fat: a growing understanding of adipocyte differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Can a selective PPARγ modulator improve glycemic control in patients with type 2 diabetes with fewer side effects compared with pioglitazone?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Hypotension, lipodystrophy, and insulin resistance in generalized PPARgamma-deficient mice rescued from embryonic lethality

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Thiazolidinediones and Cardiovascular Risk — A Question of Balance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Activation of PPARgamma increases PTEN expression in pancreatic cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

PPAR modulators and PPAR pan agonists for metabolic diseases: the next generation of drugs targeting peroxisome proliferator-activated receptors?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Macrophages, fat, and the emergence of immunometabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Medical and surgical options in the treatment of severe obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Control of peroxisome proliferator-activated receptor gamma2 stability and activity by SUMOylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

PPAR delta: an uncompletely known nuclear receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Cytotoxicity of troglitazone through PPARγ-independent pathway and p38 MAPK pathway in renal cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Liver peroxisome proliferator-activated receptor gamma contributes to hepatic steatosis, triglyceride clearance, and regulation of body fat mass.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Thiazolidinediones and the risk of lung, prostate, and colon cancer in patients with diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Risk of acute myocardial infarction, stroke, heart failure, and death in elderly Medicare patients treated with rosiglitazone or pioglitazone

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

The role of T cell PPAR gamma in mice with experimental inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Activation of peroxisome proliferator-activated receptor-gamma in dendritic cells inhibits the development of eosinophilic airway inflammation in a mouse model of asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Degradation of the peroxisome proliferator-activated receptor gamma is linked to ligand-dependent activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Adipose-specific peroxisome proliferator-activated receptor gamma knockout causes insulin resistance in fat and liver but not in muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Muscle-specific Pparg deletion causes insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Further understanding of fat biology: lessons from a fat fly

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Peroxisome proliferator-activated receptor gamma is required for regulatory CD4+ T cell-mediated protection against colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Genipin Selectively Inhibits TNF-α-activated VCAM-1 But Not ICAM-1 Expression by Upregulation of PPAR-γ in Human Endothelial Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Research resource: Diagnostic and therapeutic potential of nuclear receptor expression in lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Deletion of PPARgamma in adipose tissues of mice protects against high fat diet-induced obesity and insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

A phase II trial of rosiglitazone in patients with thyroglobulin-positive and radioiodine-negative differentiated thyroid cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Liver X receptor and peroxisome proliferator-activated receptor as integrators of lipid homeostasis and immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

PPAR-gamma AF-2 domain functions as a component of a ubiquitin-dependent degradation signal.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

The ubiquitin ligase Siah2 regulates PPARγ activity in adipocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Suppression of PPARγ through MKRN1-mediated ubiquitination and degradation prevents adipocyte differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Differential anti-proliferative actions of peroxisome proliferator-activated receptor-gamma agonists in MCF-7 breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

An inducible pathway for degradation of FLIP protein sensitizes tumor cells to TRAIL-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

The role of lipid-activated nuclear receptors in shaping macrophage and dendritic cell function: From physiology to pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

The nuclear receptor PPAR gamma selectively inhibits Th17 differentiation in a T cell-intrinsic fashion and suppresses CNS autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma)

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Combinational effect of PPARγ agonist and RXR agonist on the growth of SGC7901 gastric carcinoma cells in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Rosiglitazone, a PPAR gamma agonist: potent promoter of hydroxybutyl(butyl)nitrosamine-induced urinary bladder cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

A novel mechanism of PPAR gamma induction via EGFR signalling constitutes rational for combination therapy in bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Liver-specific disruption of PPARgamma in leptin-deficient mice improves fatty liver but aggravates diabetic phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Intestinal-specific PPARgamma deficiency enhances tumorigenesis in ApcMin/+ mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Peroxisome proliferating activating receptor gamma-independent attenuation of interleukin 6 and interleukin 8 secretion from primary endometrial stromal cells by thiazolidinediones.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Aging activates adipogenic and suppresses osteogenic programs in mesenchymal marrow stroma/stem cells: the role of PPAR-gamma2 transcription factor and TGF-beta/BMP signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Effects of ligand activation of peroxisome proliferator-activated receptor gamma in human prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Thiazolidinedione use, fluid retention, and congestive heart failure: a consensus statement from the American Heart Association and American Diabetes Association

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Regulation of chemokine and chemokine receptor expression by PPARγ in adipocytes and macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Effect of Rosiglitazone on the Risk of Myocardial Infarction and Death from Cardiovascular Causes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Muscle-specific PPARgamma-deficient mice develop increased adiposity and insulin resistance but respond to thiazolidinediones

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Alternative macrophage activation and metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Macrophage-specific PPARgamma controls alternative activation and improves insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Colorectal cancer expression of peroxisome proliferator-activated receptor gamma (PPARG, PPARgamma) is associated with good prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Before they were fat: adipocyte progenitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

The small molecule phenamil is a modulator of adipocyte differentiation and PPARgamma expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Inhibitor of DNA binding 2 is a small molecule-inducible modulator of peroxisome proliferator-activated receptor-gamma expression and adipocyte differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Resveratrol ameliorates aging-related metabolic phenotypes by inhibiting cAMP phosphodiesterases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

The different shades of fat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Eosinophils and type 2 cytokine signaling in macrophages orchestrate development of functional beige fat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Role of PPAR γ in the Differentiation and Function of Neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Pioglitazone, PPARγ agonist, attenuates experimental autoimmune neuritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Association between cancer prevalence and use of thiazolidinediones: results from the Vermont Diabetes Information System

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Activators of the nuclear receptor PPARgamma enhance colon polyp formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Peroxisome proliferator-activated receptor gamma activation can regulate beta-catenin levels via a proteasome-mediated and adenomatous polyposis coli-independent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Thiazolidenediones mediate apoptosis in prostate cancer cells in part through inhibition of Bcl-xL/Bcl-2 functions independently of PPARgamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Inflammation and the IKK beta/I kappa B/NF-kappa B axis in obesity- and diet-induced insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Targeting PPARγ Signaling Cascade for the Prevention and Treatment of Prostate Cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Bone remodeling: Multiple cellular interactions required for coupling of bone formation and resorption

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

The Key to Unlocking the Chemotherapeutic Potential of PPARγ Ligands: Having the Right Combination

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Stromal adipocyte PPARγ protects against breast tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Anti-inflammatory actions of PPAR ligands: new insights on cellular and molecular mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

The many faces of PPARgamma: anti-inflammatory by any means?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

PPARgamma, a lipid-activated transcription factor as a regulator of dendritic cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Fat and beyond: the diverse biology of PPARgamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Fatty acid metabolism, energy expenditure and insulin resistance in muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Posttranslational modifications of PPAR-gamma: fine-tuning the metabolic master regulator

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Peroxisome proliferator-activated receptor (PPAR)-alpha: a pharmacological target with a promising future

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

The PPAR-γ agonist troglitazone antagonizes survival pathways induced by STAT-3 in recombinant interferon-β treated pancreatic cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

The small molecule harmine is an antidiabetic cell-type-specific regulator of PPARgamma expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Endocrine functions of adipose tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Lipoatrophy and severe metabolic disturbance in mice with fat-specific deletion of PPARγ.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Novel insights of dietary polyphenols and obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Thiazolidinediones modulate the expression of beta-catenin and other cell-cycle regulatory proteins by targeting the F-box proteins of Skp1-Cul1-F-box protein E3 ubiquitin ligase independently of peroxisome proliferator-activated receptor gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Obesity is associated with macrophage accumulation in adipose tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Adipocyte inflammation is essential for healthy adipose tissue expansion and remodeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Epidemiologic and economic consequences of the global epidemics of obesity and diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Troglitazone inhibits growth of MCF-7 breast carcinoma cells by targeting G1 cell cycle regulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Adipocyte-specific gene expression and adipogenic steatosis in the mouse liver due to peroxisome proliferator-activated receptor gamma1 (PPARgamma1) overexpression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X

Induction of apoptosis in human and rat glioma by agonists of the nuclear receptor PPARgamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-015-0559-X