(Q38317217)

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Effect of phosphorothioate modifications on the ability of GTn oligodeoxynucleotides to specifically recognize single-stranded DNA-binding proteins and to affect human cancer cellular growth.

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2 November 2019

Effect of phosphorothioate modifications on the ability of GTn oligodeoxynucleotides to specifically recognize single-stranded DNA-binding proteins and to affect human cancer cellular growth (English)

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2 November 2019

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2 November 2019

5

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2 November 2019

author name string

C Morassutti

1

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2 November 2019

B Scaggiante

2

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2 November 2019

B Dapas

3

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2 November 2019

F Quadrifoglio

6

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2 November 2019

publication date

1 December 1999

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2 November 2019

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2 November 2019

81

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2 November 2019

12

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2 November 2019

1115-1122

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2 November 2019

Pharmacokinetics, biodistribution, and stability of capped oligodeoxynucleotide phosphorothioates in mice

1 reference

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Electron micrographic studies of transport of oligodeoxynucleotides across eukaryotic cell membranes.

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(A,G)-oligonucleotides form extraordinary stable triple helices with a critical R.Y sequence of the murine c-Ki-ras promoter and inhibit transcription in transfected NIH 3T3 cells.

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Characterization of a multisubunit human protein which selectively binds single stranded d(GA)n and d(GT)n sequence repeats in DNA.

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Regulation of mouse myelin basic protein gene transcription by a sequence-specific single-stranded DNA-binding protein in vitro

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Cloning and characterization of a single-stranded DNA binding protein that specifically recognizes deoxycytidine stretch

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Human cancer cell lines growth inhibition by GTn oligodeoxyribonucleotides recognizing single-stranded DNA-binding proteins

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Backbone modifications in oligonucleotides and peptide nucleic acid systems

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Phosphorothioate oligodeoxynucleotides bind to basic fibroblast growth factor, inhibit its binding to cell surface receptors, and remove it from low affinity binding sites on extracellular matrix

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Effect of oligomer length and base substitutions on the cytotoxic activity and specific nuclear protein recognition of GTn oligonucleotides in the human leukemic CCRF-CEM cell line

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Pathways of degradation and mechanism of action of antisense oligonucleotides in Xenopus laevis embryos

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Patterns of intracellular compartmentalization, trafficking and acidification of 5'-fluorescein labeled phosphodiester and phosphorothioate oligodeoxynucleotides in HL60 cells

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Phosphorothioate oligodeoxyribonucleotides dissociate from cationic lipids before entering the nucleus

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Phosphorothioate oligonucleotides bind in a non sequence-specific manner to the nucleolar protein C23/nucleolin

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Translation inhibition by phosphorothioate oligodeoxynucleotides in cell-free systems

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Phosphorothioate antisense oligodeoxynucleotides: questions of specificity

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Binding of phosphorothioate oligodeoxynucleotides to basic fibroblast growth factor, recombinant soluble CD4, laminin and fibronectin is P-chirality independent

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Identifiers

10.1016/S0300-9084(99)00350-8

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Europe PubMed Central

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2 November 2019

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