(Q38317858)

2 September 2017

title

The E249K mutator mutant of DNA polymerase beta extends mispaired termini (English)

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2 September 2017

2

Sweasy JB

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2 September 2017

Kosa JL

1

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2 September 2017

language of work or name

English

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publication date

1 December 1999

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Journal of Biological Chemistry

2 September 2017

published in

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2 September 2017

volume

274

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2 September 2017

issue

50

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2 September 2017

page(s)

35866-35872

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Increased activity and fidelity of DNA polymerase beta on single-nucleotide gapped DNA.

2 September 2017

cites work

1 reference

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Dominant negative rat DNA polymerase beta mutants interfere with base excision repair in Saccharomyces cerevisiae

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Requirement of mammalian DNA polymerase-beta in base-excision repair.

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Evidence for a role for DNA polymerase beta in mammalian meiosis

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Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting

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Interaction of human apurinic endonuclease and DNA polymerase beta in the base excision repair pathway

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Mammalian abasic site base excision repair. Identification of the reaction sequence and rate-determining steps

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Excision of deoxyribose phosphate residues by DNA polymerase beta during DNA repair

21 January 2018

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DNA polymerase beta and DNA synthesis in Xenopus oocytes and in a nuclear extract

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DNA polymerase beta can substitute for DNA polymerase I in the initiation of plasmid DNA replication

21 January 2018

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3'-Azido-3'-deoxythymidine-resistant mutants of DNA polymerase beta identified by in vivo selection

21 January 2018

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Development and use of an in vitro HSV-tk forward mutation assay to study eukaryotic DNA polymerase processing of DNA alkyl lesions

21 January 2018

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Low fidelity mutants in the O-helix of Thermus aquaticus DNA polymerase I.

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Rapid quench kinetic analysis of polymerases, adenosinetriphosphatases, and enzyme intermediates

21 January 2018

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DNA polymerase beta: structure-fidelity relationship from Pre-steady-state kinetic analyses of all possible correct and incorrect base pairs for wild type and R283A mutant

21 January 2018

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Fidelity mechanisms in DNA replication

21 January 2018

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Extension of mismatched 3' termini of DNA is a major determinant of the infidelity of human immunodeficiency virus type 1 reverse transcriptase.

21 January 2018

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Kinetic mechanism whereby DNA polymerase I (Klenow) replicates DNA with high fidelity

21 January 2018

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Crystal structures of human DNA polymerase beta complexed with gapped and nicked DNA: evidence for an induced fit mechanism

21 January 2018

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Crystal structures of human DNA polymerase beta complexed with DNA: implications for catalytic mechanism, processivity, and fidelity

21 January 2018

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Crystal structure at 3.5 A resolution of HIV-1 reverse transcriptase complexed with an inhibitor

21 January 2018

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Locations of anti-AIDS drug binding sites and resistance mutations in the three-dimensional structure of HIV-1 reverse transcriptase. Implications for mechanisms of drug inhibition and resistance

21 January 2018

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DNA polymerase beta conducts the gap-filling step in uracil-initiated base excision repair in a bovine testis nuclear extract.

21 January 2018

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Reconstitution of the DNA base excision-repair pathway

21 January 2018

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21 January 2018

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Involvement of phenylalanine 272 of DNA polymerase beta in discriminating between correct and incorrect deoxynucleoside triphosphates

21 January 2018

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The mutator form of polymerase beta with amino acid substitution at tyrosine 265 in the hinge region displays an increase in both base substitution and frame shift errors

21 January 2018

1 reference

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Structural insights into DNA polymerase beta fidelity: hold tight if you want it right

21 January 2018

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Sequence analysis of proviral HIV RT amplified directly by a semi-quantitative technique from AZT treated patients

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.274.50.35866

1 reference

2 September 2017

1 reference