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TPP1 OB-fold domain controls telomere maintenance by recruiting telomerase to chromosome ends
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Europe PubMed Central
PMC publication ID
3516183
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22863003%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
title
TPP1 OB-fold domain controls telomere maintenance by recruiting telomerase to chromosome ends
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
3516183
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22863003%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
main subject
OB-fold nucleic acid binding domain
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inferred from title
author
Luís F Z Batista
series ordinal
2
1 reference
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Europe PubMed Central
PMC publication ID
3516183
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22863003%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
Steven E Artandi
series ordinal
6
object named as
Steven E Artandi
1 reference
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Europe PubMed Central
PMC publication ID
3516183
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22863003%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
author name string
Franklin L Zhong
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
3516183
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22863003%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
Adam Freund
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3
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PMC publication ID
3516183
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22863003%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
Matthew F Pech
series ordinal
4
1 reference
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Europe PubMed Central
PMC publication ID
3516183
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22863003%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
Andrew S Venteicher
series ordinal
5
1 reference
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Europe PubMed Central
PMC publication ID
3516183
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22863003%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
language of work or name
English
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publication date
1 August 2012
1 reference
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Europe PubMed Central
PMC publication ID
3516183
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retrieved
9 February 2020
published in
Cell
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Europe PubMed Central
PMC publication ID
3516183
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22863003%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
volume
150
1 reference
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Europe PubMed Central
PMC publication ID
3516183
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22863003%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
issue
3
1 reference
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Europe PubMed Central
PMC publication ID
3516183
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22863003%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
page(s)
481-494
1 reference
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Europe PubMed Central
PMC publication ID
3516183
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22863003%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
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Europe PubMed Central
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11 June 2022
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https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3516183/fullTextXML
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cites work
Telomerase recruitment requires both TCAB1 and Cajal bodies independently
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516183
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6 September 2017
An enhanced H/ACA RNP assembly mechanism for human telomerase RNA
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516183
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6 September 2017
The E3 ubiquitin ligase Rnf8 stabilizes Tpp1 to promote telomere end protection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516183
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6 September 2017
Telomere protection by TPP1/POT1 requires tethering to TIN2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516183
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6 September 2017
It all comes together at the ends: telomerase structure, function, and biogenesis
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516183
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6 September 2017
Telomere shortening and loss of self-renewal in dyskeratosis congenita induced pluripotent stem cells
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516183
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6 September 2017
Hallmarks of Cancer: The Next Generation
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6 September 2017
Disruption of telomerase trafficking by TCAB1 mutation causes dyskeratosis congenita
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516183
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6 September 2017
TPP1 is required for TERT recruitment, telomere elongation during nuclear reprogramming, and normal skin development in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516183
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6 September 2017
TIN2-tethered TPP1 recruits human telomerase to telomeres in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516183
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6 September 2017
Functional interaction between telomere protein TPP1 and telomerase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516183
retrieved
6 September 2017
Telomeres: protecting chromosomes against genome instability
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516183
retrieved
6 September 2017
POT1-TPP1 enhances telomerase processivity by slowing primer dissociation and aiding translocation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516183
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6 September 2017
Telomere diseases
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stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516183
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6 September 2017
Telomere protection by TPP1 is mediated by POT1a and POT1b
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516183
retrieved
6 September 2017
Telomeres and telomerase in cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516183
retrieved
6 September 2017
A conserved WD40 protein binds the Cajal body localization signal of scaRNP particles
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516183
retrieved
6 September 2017
A human telomerase holoenzyme protein required for Cajal body localization and telomere synthesis
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516183
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6 September 2017
The Est3 protein associates with yeast telomerase through an OB-fold domain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516183
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6 September 2017
A proposed OB-fold with a protein-interaction surface in Candida albicans telomerase protein Est3
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516183
retrieved
6 September 2017
Two pathways recruit telomerase to Saccharomyces cerevisiae telomeres
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516183
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6 September 2017
The telosome/shelterin complex and its functions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516183
retrieved
6 September 2017
How shelterin protects mammalian telomeres
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516183
retrieved
6 September 2017
Telomerase reverse transcriptase is required for the localization of telomerase RNA to cajal bodies and telomeres in human cancer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516183
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6 September 2017
The role of telomere biology in bone marrow failure and other disorders
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516183
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6 September 2017
Physiological assembly and activity of human telomerase complexes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516183
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6 September 2017
Replication and protection of telomeres
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516183
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6 September 2017
Adult-onset pulmonary fibrosis caused by mutations in telomerase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516183
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6 September 2017
Telomerase mutations in families with idiopathic pulmonary fibrosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516183
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6 September 2017
RNA as a flexible scaffold for proteins: yeast telomerase and beyond.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516183
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6 September 2017
The POT1-TPP1 telomere complex is a telomerase processivity factor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516183
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6 September 2017
TPP1 is a homologue of ciliate TEBP-beta and interacts with POT1 to recruit telomerase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516183
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6 September 2017
Stepwise RNP assembly at the site of H/ACA RNA transcription in human cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516183
retrieved
6 September 2017
Telomere length homeostasis requires that telomerase levels are limiting
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516183
retrieved
6 September 2017
Shelterin: the protein complex that shapes and safeguards human telomeres
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516183
retrieved
6 September 2017
Mutations in TERT, the gene for telomerase reverse transcriptase, in aplastic anemia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516183
retrieved
6 September 2017
Human protection of telomeres 1 (POT1) is a negative regulator of telomerase activity in vitro
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516183
retrieved
6 September 2017
Structure of human POT1 bound to telomeric single-stranded DNA provides a model for chromosome end-protection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516183
retrieved
6 September 2017
A dynamic molecular link between the telomere length regulator TRF1 and the chromosome end protector TRF2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516183
retrieved
6 September 2017
POT1-interacting protein PIP1: a telomere length regulator that recruits POT1 to the TIN2/TRF1 complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516183
retrieved
6 September 2017
Regulation of telomerase by telomeric proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516183
retrieved
6 September 2017
PTOP interacts with POT1 and regulates its localization to telomeres
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516183
retrieved
6 September 2017
TIN2 is a tankyrase 1 PARP modulator in the TRF1 telomere length control complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516183
retrieved
6 September 2017
From silencing to gene expression: real-time analysis in single cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516183
retrieved
6 September 2017
Beginning to understand the end of the chromosome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516183
retrieved
6 September 2017
Telomerase RNA Accumulates in Cajal Bodies in Human Cancer Cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516183
retrieved
6 September 2017
DNA damage foci at dysfunctional telomeres
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516183
retrieved
6 September 2017
POT1 as a terminal transducer of TRF1 telomere length control
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516183
retrieved
6 September 2017
C-terminal regions of the human telomerase catalytic subunit essential for in vivo enzyme activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516183
retrieved
6 September 2017
Cdc13 delivers separate complexes to the telomere for end protection and replication
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516183
retrieved
6 September 2017
Cajal bodies: the first 100 years
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516183
retrieved
6 September 2017
Control of human telomere length by TRF1 and TRF2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516183
retrieved
6 September 2017
hTERT mutations associated with idiopathic pulmonary fibrosis affect telomerase activity, telomere length, and cell growth by distinct mechanisms
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516183
retrieved
6 September 2017
Putative Telomere-Recruiting Domain in the Catalytic Subunit of Human Telomerase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516183
retrieved
14 September 2017
Human telomerase RNA and box H/ACA scaRNAs share a common Cajal body-specific localization signal.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516183
retrieved
31 August 2018
Human telomerase RNA accumulation in Cajal bodies facilitates telomerase recruitment to telomeres and telomere elongation
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22863003
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Est1p as a cell cycle-regulated activator of telomere-bound telomerase
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22863003
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.CELL.2012.07.012
1 reference
stated in
Europe PubMed Central
PMC publication ID
3516183
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22863003%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
PMC publication ID
3516183
1 reference
stated in
Europe PubMed Central
PMC publication ID
3516183
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22863003%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
PubMed publication ID
22863003
1 reference
stated in
Europe PubMed Central
PMC publication ID
3516183
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22863003%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
ResearchGate publication ID
230618143
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