(Q38326633)

2 September 2017

title

Lack of microRNA-101 causes E-cadherin functional deregulation through EZH2 up-regulation in intestinal gastric cancer (English)

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2 September 2017

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11

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13

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Heike Irmgard Grabsch

8

object named as

Heike Grabsch

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2 September 2017

Patricia M Pereira

3

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Joana Carvalho

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Joana Carvalho

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Gerrit Meijer

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object named as

Gerrit Meijer

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2 September 2017

Nicole C van Grieken

2

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2 September 2017

Sónia Sousa

4

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Marianne Tijssen

5

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Tineke E Buffart

6

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Begoña Diosdado

7

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Manuel A S Santos

9

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Beatriz Carvalho

12

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2 September 2017

publication date

23 May 2012

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2 September 2017

volume

228

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issue

1

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2 September 2017

page(s)

31-44

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Global cancer statistics, 2002

2 September 2017

cites work

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Molecular targets and biological modifiers in gastric cancer

21 January 2018

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E-cadherin germline mutations in familial gastric cancer.

21 January 2018

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Germline CDH1 deletions in hereditary diffuse gastric cancer families

21 January 2018

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Quantification of epigenetic and genetic 2nd hits in CDH1 during hereditary diffuse gastric cancer syndrome progression.

21 January 2018

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Mechanisms inactivating the gene for E-cadherin in sporadic gastric carcinomas

21 January 2018

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Mutations of the human E-cadherin (CDH1) gene.

21 January 2018

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E-cadherin regulates metastasis of pancreatic cancer in vivo and is suppressed by a SNAIL/HDAC1/HDAC2 repressor complex

21 January 2018

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The tumor suppressor gene rap1GAP is silenced by miR-101-mediated EZH2 overexpression in invasive squamous cell carcinoma

21 January 2018

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Role of histone H3 lysine 27 methylation in Polycomb-group silencing

21 January 2018

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Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein

21 January 2018

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The functions of E(Z)/EZH2-mediated methylation of lysine 27 in histone H3.

21 January 2018

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Repression of E-cadherin by the polycomb group protein EZH2 in cancer

21 January 2018

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Enhancer of zeste homolog 2 downregulates E-cadherin by mediating histone H3 methylation in gastric cancer cells

21 January 2018

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The polycomb group protein EZH2 is involved in progression of prostate cancer

21 January 2018

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EZH2 expression is associated with high proliferation rate and aggressive tumor subgroups in cutaneous melanoma and cancers of the endometrium, prostate, and breast

21 January 2018

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Expression of the enhancer of zeste homolog 2 is correlated with poor prognosis in human gastric cancer.

21 January 2018

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High expression of EZH2 is associated with tumor proliferation and prognosis in human oral squamous cell carcinomas

21 January 2018

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EZH2 supports ovarian carcinoma cell invasion and/or metastasis via regulation of TGF-beta1 and is a predictor of outcome in ovarian carcinoma patients.

21 January 2018

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Expression of enhancer of zeste homologue 2 is significantly associated with increased tumor cell proliferation and is a marker of aggressive breast cancer

21 January 2018

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The enhancer of zeste homolog 2 gene contributes to cell proliferation and apoptosis resistance in renal cell carcinoma cells

21 January 2018

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EZH2 depletion blocks the proliferation of colon cancer cells

21 January 2018

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Survival prediction of gastric cancer by a seven-microRNA signature

21 January 2018

1 reference

Relation between microRNA expression and progression and prognosis of gastric cancer: a microRNA expression analysis

21 January 2018

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miR-101 is down-regulated in glioblastoma resulting in EZH2-induced proliferation, migration, and angiogenesis

21 January 2018

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MiR-101 downregulation is involved in cyclooxygenase-2 overexpression in human colon cancer cells.

21 January 2018

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MicroRNA-101, down-regulated in hepatocellular carcinoma, promotes apoptosis and suppresses tumorigenicity

21 January 2018

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MicroRNA-101 is down-regulated in gastric cancer and involved in cell migration and invasion

21 January 2018

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Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer

21 January 2018

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The putative tumor suppressor microRNA-101 modulates the cancer epigenome by repressing the polycomb group protein EZH2.

21 January 2018

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MicroRNA-101 negatively regulates Ezh2 and its expression is modulated by androgen receptor and HIF-1alpha/HIF-1beta

21 January 2018

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Establishment and characterization of two cell lines derived from human diffuse gastric carcinomas xenografted in nude mice.

21 January 2018

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MicroRNA expression variability in human cervical tissues

21 January 2018

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

21 January 2018

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The NMD mRNA surveillance pathway downregulates aberrant E-cadherin transcripts in gastric cancer cells and in CDH1 mutation carriers

21 January 2018

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MicroRNA-101 regulates expression of the v-fos FBJ murine osteosarcoma viral oncogene homolog (FOS) oncogene in human hepatocellular carcinoma

21 January 2018

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Epigenetic regulation of microRNA-10b and targeting of oncogenic MAPRE1 in gastric cancer

21 January 2018

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miR-152 is a tumor suppressor microRNA that is silenced by DNA hypermethylation in endometrial cancer

21 January 2018

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FGF-2 regulates cell proliferation, migration, and angiogenesis through an NDY1/KDM2B-miR-101-EZH2 pathway

21 January 2018

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Enforced expression of miR-101 inhibits prostate cancer cell growth by modulating the COX-2 pathway in vivo

21 January 2018

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Tumour-suppressor microRNAs let-7 and mir-101 target the proto-oncogene MYCN and inhibit cell proliferation in MYCN-amplified neuroblastoma

21 January 2018

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PKCalpha mediated induction of miR-101 in human hepatoma HepG2 cells

21 January 2018

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Integrative genomics analysis reveals silencing of beta-adrenergic signaling by polycomb in prostate cancer

21 January 2018

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Enhancer of zeste homologue 2 (EZH2) down-regulates RUNX3 by increasing histone H3 methylation

21 January 2018

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Somatic mutations of the histone methyltransferase gene EZH2 in myelodysplastic syndromes

21 January 2018

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Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders

21 January 2018

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Gastric cancers in young and elderly patients show different genomic profiles.

21 January 2018

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Methylation of the CDH1 promoter as the second genetic hit in hereditary diffuse gastric cancer

21 January 2018

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Screening E-cadherin in gastric cancer families reveals germline mutations only in hereditary diffuse gastric cancer kindred

21 January 2018

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E-cadherin gene (CDH1) promoter methylation as the second hit in sporadic diffuse gastric carcinoma

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/PATH.4032

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2 September 2017

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