(Q38328861)

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Restoration of transcriptional activity of p53 mutants in human tumour cells by intracellular expression of anti-p53 single chain Fv fragments

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scholarly article

1 reference

Europe PubMed Central

2 September 2017

Restoration of transcriptional activity of p53 mutants in human tumour cells by intracellular expression of anti-p53 single chain Fv fragments (English)

1 reference

Europe PubMed Central

2 September 2017

author name string

Caron de Fromentel C

1

1 reference

Europe PubMed Central

2 September 2017

Gruel N

2

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Europe PubMed Central

2 September 2017

Venot C

3

1 reference

Europe PubMed Central

2 September 2017

Debussche L

4

1 reference

Europe PubMed Central

2 September 2017

Conseiller E

5

1 reference

Europe PubMed Central

2 September 2017

Dureuil C

6

1 reference

Europe PubMed Central

2 September 2017

Teillaud JL

7

1 reference

Europe PubMed Central

2 September 2017

Tocque B

8

1 reference

Europe PubMed Central

2 September 2017

Bracco L

9

1 reference

Europe PubMed Central

2 September 2017

language of work or name

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publication date

1 January 1999

1 reference

Europe PubMed Central

2 September 2017

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Europe PubMed Central

2 September 2017

18

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Europe PubMed Central

2 September 2017

551-557

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Europe PubMed Central

2 September 2017

2

1 reference

Europe PubMed Central

2 September 2017

https://scigraph.springernature.com/pub.10.1038/sj.onc.1202338

0 references

Suppression of human colorectal carcinoma cell growth by wild-type p53

1 reference

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The carboxyl-terminal domain of the p53 protein regulates sequence-specific DNA binding through its nonspecific nucleic acid-binding activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202338

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Induction of the growth inhibitor IGF-binding protein 3 by p53

1 reference

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p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202338

7 January 2021

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Thymocyte apoptosis induced by p53-dependent and independent pathways.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202338

7 January 2021

based on heuristic

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WAF1, a potential mediator of p53 tumor suppression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202338

7 January 2021

based on heuristic

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The p53 proto-oncogene can act as a suppressor of transformation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202338

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A transcriptionally active DNA-binding site for human p53 protein complexes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202338

7 January 2021

based on heuristic

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Database of p53 gene somatic mutations in human tumors and cell lines: updated compilation and future prospects

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202338

7 January 2021

based on heuristic

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Induction of apoptosis in HeLa cells by trans-activation-deficient p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202338

7 January 2021

based on heuristic

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Conformational shifts propagate from the oligomerization domain of p53 to its tetrameric DNA binding domain and restore DNA binding to select p53 mutants.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202338

7 January 2021

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inferred from DOI database lookup

Monoclonal antibodies specific for simian virus 40 tumor antigens

1 reference

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7 January 2021

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Regulation of the specific DNA binding function of p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202338

7 January 2021

based on heuristic

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Activation of the cryptic DNA binding function of mutant forms of p53.

1 reference

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7 January 2021

based on heuristic

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Allosteric activation of latent p53 tetramers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202338

7 January 2021

based on heuristic

inferred from DOI database lookup

Small peptides activate the latent sequence-specific DNA binding function of p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202338

7 January 2021

based on heuristic

inferred from DOI database lookup

Characterization of scFv-421, a single-chain antibody targeted to p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202338

7 January 2021

based on heuristic

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A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202338

7 January 2021

based on heuristic

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p53: puzzle and paradigm

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202338

7 January 2021

based on heuristic

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p53 and its 14 kDa C-terminal domain recognize primary DNA damage in the form of insertion/deletion mismatches

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202338

7 January 2021

based on heuristic

inferred from DOI database lookup

p53, the cellular gatekeeper for growth and division

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202338

7 January 2021

based on heuristic

inferred from DOI database lookup

Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202338

7 January 2021

based on heuristic

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p53 is required for radiation-induced apoptosis in mouse thymocytes

1 reference

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7 January 2021

based on heuristic

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Differential induction of transcriptionally active p53 following UV or ionizing radiation: defects in chromosome instability syndromes?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202338

7 January 2021

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Intrabodies: turning the humoral immune system outside in for intracellular immunization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202338

7 January 2021

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Negative growth regulation in a glioblastoma tumor cell line that conditionally expresses human wild-type p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202338

7 January 2021

based on heuristic

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Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202338

7 January 2021

based on heuristic

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Disrupting the hydrophobic patches at the antibody variable/constant domain interface: improved in vivo folding and physical characterization of an engineered scFv fragment.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202338

7 January 2021

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Cloning immunoglobulin variable domains for expression by the polymerase chain reaction

1 reference

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Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202338

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based on heuristic

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The DNA-binding domain of p53 contains the four conserved regions and the major mutation hot spots

1 reference

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7 January 2021

based on heuristic

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A model for p53-induced apoptosis

1 reference

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Phenotypic knockout of the high-affinity human interleukin 2 receptor by intracellular single-chain antibodies against the alpha subunit of the receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202338

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based on heuristic

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Restoration of the growth suppression function of mutant p53 by a synthetic peptide derived from the p53 C-terminal domain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202338

7 January 2021

based on heuristic

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Identification of a novel p53 functional domain that is necessary for efficient growth suppression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202338

7 January 2021

based on heuristic

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The dihedral symmetry of the p53 tetramerization domain mandates a conformational switch upon DNA binding

1 reference

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based on heuristic

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Induction of cellular p53 activity by DNA-damaging agents and growth arrest.

1 reference

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Identifiers

10.1038/SJ.ONC.1202338

1 reference

Europe PubMed Central

2 September 2017

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1 reference

Europe PubMed Central

2 September 2017

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